Abstract Pulmonary hypertension, defined as a mean pulmonary artery pressure (PAP) > 25 mmHg, is a serious condition that can lead to right heart failure and death. It can result from a wide variety of disease processes, many of which are highly prevalent in obese populations. The exact rates of pulmonary hypertension in patients with obesity remain unclear but appear high. Emerging data from animal models suggest some pathologic mechanisms by which obesity and the metabolic syndrome may contribute to the development of pulmonary vascular disease, but the roles of the majority of these mechanisms in the development of pulmonary hypertension in human subjects are yet to be elucidated.
Obesity and pulmonary hypertension
Published 2019 in Mechanisms and Manifestations of Obesity in Lung Disease
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2019
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Mechanisms and Manifestations of Obesity in Lung Disease
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Medicine, Environmental Science
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