Cell Signaling by Endothelin Peptides

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Handbook of experimental pharmacology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-3-642-56899-2_5
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular mechanisms of endothelin-1-induced cell-cycle progression: involvement of extracellular signal-regulated kinase, protein kinase C, and phosphatidylinositol 3-kinase at distinct points.

  1999cited by this paper
• Pathophysiology of endothelin in the cardiovascular system.

  1999cited by this paper
• Signal transduction through MAP kinase cascades.

  1998cited by this paper
• Endothelin-1 is a potent survival factor for c-Myc-dependent apoptosis.

  1998cited by this paper
• A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.

  1998cited by this paper
• c-Src Activation Plays a Role in Endothelin-dependent Hypertrophy of the Cardiac Myocyte*

  1998cited by this paper
• Differential activation of phosphoinositide 3-kinase by endothelin and ceramide in colonic smooth muscle cells.

  1998cited by this paper
• Cyclin D1, p16, and retinoblastoma gene regulate mitogenic signaling of endothelin in rat mesangial cells.

  1998cited by this paper
• Activation of two types of Ca2+‐permeable nonselective cation channel by endothelin‐1 in A7r5 cells

  1998cited by this paper
• Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy.

  1998cited by this paper
• Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice.

  1998cited by this paper
• Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.

  1998cited by this paper
• Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice.

  1998cited by this paper
• Mechanisms of Endothelin-Induced Mitogenesis and Activation of Stress Response Protein Kinases

  1998cited by this paper
• Endothelin Receptors and Signaling Mechanisms

  1998cited by this paper
• Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy?

  1998cited by this paper
• Atrial natriuretic peptide inhibits endothelin-1-induced activation of JNK in glomerular mesangial cells.

  1998cited by this paper
• Introduction to the Endothelin System

  1998cited by this paper
• Role of nonselective cation channels as Ca2+ entry pathway in endothelin-1-induced contraction and their suppression by nitric oxide.

  1998cited by this paper
• Biphasic activation of p21ras by endothelin‐1 sequentially activates the ERK cascade and phosphatidylinositol 3‐kinase

  1997cited by this paper
• Endothelin-1 activates c-Jun NH2-terminal kinase in mesangial cells.

  1997cited by this paper
• PI3K: downstream AKTion blocks apoptosis.

  1997cited by this paper
• Endothelins in the normal and diseased kidney.

  1997cited by this paper
• Apoptosis in aorta of deoxycorticosterone acetate‐salt hypertensive rats: effect of endothelin receptor antagonism

  1997cited by this paper
• Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells.

  1997cited by this paper
• Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation.

  1997cited by this paper
• Endothelin attenuates apoptosis in human smooth muscle cells.

  1997cited by this paper
• Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes.

  1997cited by this paper
• Specific repression of the preproendothelin-1 gene in intracranial arteriovenous malformations.

  1997cited by this paper
• Elementary and global aspects of calcium signalling.

  1997cited by this paper
• Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells.

  1997cited by this paper
• Regulation, substrates and functions of src.

  1996cited by this paper
• Blood vessel formation: what is its molecular basis?

  1996cited by this paper
• Characterization of the renal phenotype of transgenic rats expressing the human endothelin-2 gene.

  1996cited by this paper
• Ca2+ channels mediate protein tyrosine kinase activation by endothelin-1.

  1996cited by this paper
• A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK

  1996cited by this paper
• Endothelin-1-induced mitogenic responses of Chinese hamster ovary cells expressing human endothelinA: the role of a wortmannin-sensitive signaling pathway.

  1996cited by this paper
• Nuclear Signaling by Endothelin-1 Requires Src Protein-tyrosine Kinases (*)

  1996cited by this paper
• Blocking both type A and B endothelin receptors in the kidney attenuates renal injury and prolongs survival in rats with remnant kidney.

  1996cited by this paper
• Endothelin receptor-mediated signaling in hirschsprung disease.

  1996cited by this paper
• Transformation of Rat-1 fibroblasts with the v-src oncogene increases the tyrosine phosphorylation state and activity of the alpha subunit of Gq/G11.

  1996cited by this paper
• Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

  1996cited by this paper
• 1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes.

  1996cited by this paper
• Mitogenic signaling via G protein-coupled receptors.

  1996cited by this paper
• Endothelin 3 promotes neural crest cell proliferation and mediates a vast increase in melanocyte number in culture.

  1996cited by this paper
• Nuclear signaling by endothelin-1. A Ras pathway for activation of the c-fos serum response element

  1995cited by this paper
• Signal transduction through integrins: A central role for focal adhesion kinase?

  1995cited by this paper
• DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases

  1995cited by this paper
• Retinoid-dependent pathways suppress myocardial cell hypertrophy.

  1995cited by this paper
• Endothelin receptors and calcium signaling 1

  1995cited by this paper
• Possible role of endothelin in endothelial regulation of vascular tone.

  1995cited by this paper
• Endothelin-1 stimulates tyrosine phosphorylation of p125 focal adhesion kinase in mesangial cells.

  1995cited by this paper
• Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

  1995cited by this paper
• Endothelin-1 expression by human hepatocellular carcinoma.

  1995cited by this paper
• Orally Active Endothelin Receptor Antagonist BMS‐182874 Suppresses Neointimal Development in Balloon‐Injured Rat Carotid Arteries

  1995cited by this paper
• Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.

  1995cited by this paper
• The endothelin system. A new target for therapeutic intervention.

  1994cited by this paper
• Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells.

  1994cited by this paper
• Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice.

  1994cited by this paper
• A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670.

  1994cited by this paper
• Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanisms.

  1994cited by this paper
• Endothelin induces tyrosine phosphorylation and GRB2 association of Shc in astrocytes.

  1994cited by this paper
• Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.

  1994cited by this paper
• Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1

  1994cited by this paper
• Paracrine interactions between fibroblasts and endothelial cells in a serum-free coculture model. Modulation of angiogenesis and collagen gel contraction.

  1994cited by this paper
• Endothelins stimulate mitogen-activated protein kinase cascade through either ETA or ETB.

  1994cited by this paper
• A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease.

  1994cited by this paper
• Root development in Arabidopsis: four mutants with dramatically altered root morphogenesis.

  1993cited by this paper
• Endothelins: multifunctional renal peptides.

  1993cited by this paper
• Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1. Cross-talk between G protein-coupled receptors and pp60c-src.

  1993cited by this paper
• Endothelin 1 mediates endothelial cell-dependent proliferation of vascular pericytes.

  1993cited by this paper
• Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.

  1993cited by this paper
• Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

  1993cited by this paper
• A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression.

  1993cited by this paper
• Growth regulatory properties of endothelins.

  1993cited by this paper
• Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice.

  1993cited by this paper
• The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells.

  1993cited by this paper
• Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate.

  1992cited by this paper
• Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells.

  1992cited by this paper
• Endothelin in a model of acute ischemic renal dysfunction: modulating action of atrial natriuretic factor.

  1992cited by this paper
• Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation.

  1992cited by this paper
• Molecular cloning and expression of chicken C-terminal Src kinase: lack of stable association with c-Src protein.

  1992cited by this paper
• Stimulation of anchorage-independent cell growth by endothelin in NRK 49F cells.

  1992cited by this paper
• Selective amplification of endothelin-stimulated inositol 1,4,5-trisphosphate and calcium signaling by v-src transformation of rat-1 fibroblasts.

  1992cited by this paper
• Coupling of two endothelin receptor subtypes to differing signal transduction in transfected Chinese hamster ovary cells.

  1992cited by this paper
• The effect of endothelin 1 on the retinal microvascular pericyte.

  1992cited by this paper
• Calcium-dependent increase in tyrosine kinase activity stimulated by angiotensin II.

  1992cited by this paper
• Characterization of endothelin 1 receptor and signal transduction mechanisms in rat medullary interstitial cells.

  1991cited by this paper
• Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells.

  1991cited by this paper
• Endothelin- and oxytocin-induced calcium signaling in cultured human myometrial cells.

  1991cited by this paper
• Endothelin-1-induced vasoconstriction in humans. Reversal by calcium channel blockade but not by nitrovasodilators or endothelium-derived relaxing factor.

  1991cited by this paper
• Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells.

  1991cited by this paper
• Endothelins produced by endothelial cells promote collagen gel contraction by fibroblasts

  1991cited by this paper
• Ca2+ signaling by distinct endothelin peptides in glomerular mesangial cells.

  1991cited by this paper
• Oncogenes and signal transduction.

  1991cited by this paper
• SK&F 96365, a receptor-mediated calcium entry inhibitor, inhibits calcium responses to endothelin-1 in NG108-15 cells.

  1991cited by this paper
• Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis.

  1991cited by this paper
• Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells.

  1991cited by this paper
• Activation of multiple signal transduction pathways by endothelin in cultured human vascular smooth muscle cells.

  1990cited by this paper
• Endothelin augments unitary calcium channel currents on the smooth muscle cell membrane of guinea‐pig portal vein.

  1990cited by this paper

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