Correlation between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of some Medicinal Plants

Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing the skin problems. Skin protection is a suitable method against ultraviolet radiation-induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they have limited usage. Natural substances have been recently considered as potential sunscreen resources due to their absorption in the UV region and their antioxidant activity. In the present study, the UV protective effects of 20 extracts from four common medicinal plants were evaluated. Their phenol and flavonoid contents and antioxidant activities were determined and correlation between SPF and these contents were evaluated. SPFs were between 0.102 and 24.470. The highest value was reached with ultrasonic extract of Crataegus pentagyna (SPF = 24.47) followed by methanolic extract of Feijoa sellowiana (SPF = 1.30). Good correlation was found between SPF and phenolic contents (Correlation Coefficient = 0.55 and p = 0.01) but no correlations were found between SPF and flavonoid contents or antioxidant activity. These extracts can be used alone or as additives in other sun screen formulations to enhance their SPF.

• Publication year

  2014

• Venue

  Iranian journal of pharmaceutical research

• Publication date

  2014-07-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.22037/IJPR.2014.1554PMID 25276206PMCID 4177626
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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