Association of the heat shock protein hsp90 with steroid hormone receptors and tyrosine kinase oncogene products.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1986-08-14

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0006-291X(86)80424-7PMID 3530253
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molybdate-stabilized nonactivated glucocorticoid-receptor complexes contain a 90-kDa non-steroid-binding phosphoprotein that is lost on activation.

  1986cited by this paper
• Characterization of the monomeric and complex-associated forms of the gag-onc fusion proteins of three isolates of feline sarcoma virus: phosphorylation, kinase activity, acylation, and kinetics of complex formation.

  1986cited by this paper
• Cloning of the chick hsp 90 cDNA in expression vector.

  1985cited by this paper
• Chick oviduct glucocorticosteroid receptor. Specific binding of the synthetic steroid RU 486 and immunological studies with antibodies to chick oviduct progesterone receptor.

  1985cited by this paper
• Double‐stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat‐shock protein in animal cell extracts.

  1985cited by this paper
• The common 90‐kd protein component of non‐transformed ‘8S’ steroid receptors is a heat‐shock protein.

  1985cited by this paper
• Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

  1985cited by this paper
• Isolation of steroid receptor binding protein from chicken oviduct and production of monoclonal antibodies.

  1985cited by this paper
• A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

  1985cited by this paper
• Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

  1984cited by this paper
• Progesterone receptor subunits are high-affinity substrates for phosphorylation by epidermal growth factor receptor.

  1984cited by this paper
• Progesterone receptor in the chick oviduct: an immunohistochemical study with antibodies to distinct receptor components

  1984cited by this paper
• Polypeptide components of two 8 S forms of chicken oviduct progesterone receptor.

  1984cited by this paper
• Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein

  1984cited by this paper
• Biological and biochemical characterization of a new isolate of feline sarcoma virus: Theilen-Pedersen (TP1-FeSV).

  1984cited by this paper
• Purification by affinity chromatography and immunological characterization of a 110kDa component of the chick oviduct progesterone receptor.

  1984cited by this paper
• Association of the transforming proteins of Rous, Fujinami, and Y73 avian sarcoma viruses with the same two cellular proteins

  1982cited by this paper
• Transit of pp60v-src to the plasma membrane.

  1982cited by this paper
• The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins

  1982cited by this paper
• "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

  1981cited by this paper
• A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein.

  1981cited by this paper
• The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins.

  1981cited by this paper
• Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus.

  1981cited by this paper
• Simultaneous injection of newborn rabbits with the Schmidt-Ruppin and prague strains of Rous sarcoma virus induces antibodies which recognize the pp60src of both strains.

  1980cited by this paper
• Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

  1980cited by this paper
• Molybdate inhibition of glucocorticoid receptor inactivation and transformation.

  1979cited by this paper
• ATP-dependent activation of L cell glucocorticoid receptors to the steroid binding form.

  1979cited by this paper
• Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo

  1978cited by this paper
• Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

  1977cited by this paper
• A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

  1974cited by this paper
• The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant.

  1971cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Glucocorticoid receptor complexes form cooperatively with the Hsp90 co-chaperones Pp5 and FKBPs

  2020cites this paper
• HSP90: A Key Player in Metal-Induced Carcinogenesis?

  2019cites this paper
• Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress

  2019cites this paper
• Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α

  2018cites this paper
• The stress response paradox: fighting degeneration at the cost of cancer

  2016cites this paper
• Hsp90: Friends, clients and natural foes.

  2016cites this paper
• Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer Treatment

  2015cites this paper
• Heat shock protein 90β stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells.

  2014cites this paper
• Mouse monoclonal antibodies against estrogen receptor.

  2014cites this paper
• The Pivotal Role of CK2 in the Kinome‐Targeting Hsp90 Chaperone Machinery

  2013cites this paper
• The therapeutic target Hsp90 and cancer hallmarks.

  2012cites this paper
• The universe of Hsp 90

  2012cites this paper
• The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones.

  2012cites this paper
• The universe of Hsp90

  2012cites this paper
• Regulation of the Apoptosome in Cancer

  2012cites this paper
• Role of Hsp105 in CFTR biogenesis

  2010cites this paper
• Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program.

  2008cites this paper
• The Hsp90 Family of Molecular Chaperones

  2008cites this paper
• Cdc 37 is a molecular chaperone with specific functions in signal transductlon

  2007cites this paper
• HSP90 Co-Chaperones in Saccharomyces Cerevisiae

  2007cites this paper
• Targeting Hsp90: The Cancer Super-Chaperone

  2007cites this paper
• Heat shock protein 90: a unique chemotherapeutic target.

  2006cites this paper
• Using natural product inhibitors to validate Hsp90 as a molecular target in cancer.

  2006cites this paper
• The Mr ~ 90,000 Heat Shock Protein: An Important Modulator of Ligand and DNA-binding Properties of the Glucocorticoid Receptor1

  2006cites this paper
• Assays for pharmacodynamic analysis of histone deacetylase inhibitors

  2006cites this paper
• Down-Regulation of a MT 90,000 Heat Shock Cognate Protein during Granulocytic Differentiation in HL-60 Human Leukemia Cells1

  2006cites this paper
• The Role of Molecular Chaperones in the ER Associated Degradation of the Cystic Fibrosis Transmembrane Conductance Regulator in the Budding Yeast S. cerevisiae

  2006cites this paper
• REDOX PROTEOMICS IDENTIFICATION OF OXIDATIVELY MODIFIED PROTEINS AND THEIR PHARMACOLOGICAL MODULATION: INSIGHT INTO OXIDATIVE STRESS IN BRAIN AGING, AGE-RELATED COGNITIVE IMPAIRMENT

  2005cites this paper
• Hsp70 and Hsp90--a relay team for protein folding.

  2004cites this paper
• Heat-inducible rice hsp82 and hsp70 are not always co-regulated

  2004cites this paper
• Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain.

  2004cites this paper
• Development of small molecule Hsp90 inhibitors: utilizing both forward and reverse chemical genomics for drug identification.

  2003cites this paper
• Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1

  2003cites this paper
• Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation.

  2002cites this paper
• Heat Shock Response: Cellular and Molecular Responses to Stress, Misfolded Proteins, and Diseases Associated with Protein Aggregation

  2002cites this paper
• Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents

  2002cites this paper
• Phosphatidic Acid Regulates Tyrosine Phosphorylating Activity in Human Neutrophils

  2001cites this paper
• Gene expression during heat-shock in embryogenic carrot cell lines

  2001cites this paper
• Linkage of Rapid Estrogen Action to MAPK Activation by ER-Shc Association and Shc Pathway Activation

  2001cites this paper
• Substrate-binding characteristics of proteins in the 90 kDa heat shock protein family.

  2001cites this paper
• Hsp90: Chaperoning signal transduction

  2001cites this paper
• Role of the heat shock response and molecular chaperones in oncogenesis and cell death.

  2000cites this paper
• Chaperones in cell cycle regulation and mitogenic signal transduction: a review

  2000cites this paper
• Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).

  2000influential citation
• A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37.

  1999cites this paper
• Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.

  1998cites this paper
• The hsp90-based Chaperone System: Involvement in Signal Transduction from a Variety of Hormone and Growth Factor Receptors

  1998cites this paper
• Associate Editor: D. Shugar The 90-kDa Molecular Chaperone Family: Structure, Function, and Clinical Applications. A Comprehensive Review

  1998cites this paper
• Interaction of Vault Particles with Estrogen Receptor in the MCF-7 Breast Cancer Cell

  1998cites this paper
• Constitutive expression of heat shock proteins hsp90, hsc70, hsp70 and hsp60 in the rat during postnatal development

  1998cites this paper
• Murine 86-kDa heat shock protein gene and promoter.

  1997cites this paper
• Cdc37 is a molecular chaperone with specific functions in signal transduction.

  1997cites this paper
• Genomic organization of hsp90 gene family in Arabidopsis

  1997cites this paper
• Analysis of the transcriptional activity of amplified genes in tumour cells by fluorescence in situ hybridization

  1997cites this paper
• Steroid receptor interactions with heat shock protein and immunophilin chaperones.

  1997cites this paper
• A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37.

  1997cites this paper
• UVB Irradiation Induces Changes in Cellular Localization and Phosphorylation of Mouse HSP27

  1997cites this paper
• Protein phosphorylation and dephosphorylation in physiologic and oncologic processes.

  1996cites this paper
• Expression and crystallization of the yeast Hsp82 chaperone, and preliminary x‐ray diffraction studies of the amino‐terminal domain

  1996cites this paper
• Human HSP90 isoforms

  1996cites this paper
• Developmental expression of heat shock protein 60 (HSP60) in the rat testis and ovary.

  1996cites this paper
• Identification and Characterization of Novel Genes Modulated in the Thyroid of Dogs Treated with Methimazole and Propylthiouracil*

  1996cites this paper
• Molecular chaperoning of steroid hormone receptors.

  1996cites this paper
• Mechanism of dimer formation of the 90-kDa heat-shock protein.

  1995cites this paper
• Transcription factors 3: nuclear receptors.

  1995cites this paper
• Evidence for a 90 kDa heat-shock protein gene expression in the amphibian oocyte.

  1995cites this paper
• Steroid Receptor Associated Proteins: Heat Shock Protein 90 and P59 Immunophilin

  1994cites this paper
• Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90.

  1994cites this paper
• Paracrine mechanisms of gonadotrophin action on the ovary

  1994cites this paper
• Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function.

  1994cites this paper
• ATP induces a conformational change of the 90-kDa heat shock protein (hsp90).

  1993cites this paper
• Stress-induced heat-shock protein synthesis in peripheral leukocytes of turkeys, Meleagris gallopavo☆☆☆

  1993cites this paper
• Analysis of the resistance to heat and hydrogen peroxide stresses in COS cells transiently expressing wild type or deletion mutants of the Drosophila 27-kDa heat-shock protein.

  1993cites this paper
• Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells.

  1993cites this paper
• Translational Regulation in Reticulocytes

  1993cites this paper
• Heat-induced unresponsiveness of heat shock gene expression is regulated at the transcriptional level.

  1993cites this paper
• Autoregulation of the Heat-Shock Response

  1993cites this paper
• HSP86 and HSP84 exhibit cellular specificity of expression and co-precipitate with an HSP70 family member in the murine testis.

  1993cites this paper
• Widespread constitutive expression of HSP90 messenger RNA in rat brain

  1993cites this paper
• Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84)

  1992cites this paper
• A model for the determination of the 3D-spatial distribution of the functions of the hormone-binding domain of receptors that bind 3-keto-4-ene steroids.

  1992cites this paper
• High constitutive expression of heat shock protein 90α in human acute leukemia cells

  1992cites this paper
• Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells

  1992cites this paper
• High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells.

  1992cites this paper
• Mapping of the gene family for human heat-shock protein 90α to chromosomes 1, 4, 11, and 14

  1992cites this paper
• Relationship of heat shock proteins and induced thermal resistance

  1992cites this paper
• Role of membrane components in thermal injury of cells and development of thermotolerance.

  1992cites this paper
• Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates.

  1992cites this paper
• Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.

  1992cites this paper
• Unsaturable dihydrotestosterone binding suppressed by testosterone in cytosol from C57BL/6 female mice

  1991cites this paper
• Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000.

  1991cites this paper
• The 90-kDa heat shock protein (hsp-90) possesses an ATP binding site and autophosphorylating activity.

  1991cites this paper
• Stress Proteins

  1991cites this paper
• Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11.

  1991cites this paper
• Constitutive overexpression of a 89 kDa heat shock protein gene in the HBL100 human mammary cell line converted to a tumorigenic phenotype by the EJ/T24 Harvey-ras oncogene.

  1991cites this paper
• Diverse groups of plant RNA and DNA viruses share related movement proteins that may possess chaperone-like activity.

  1991cites this paper
• Estradiol increases phosphorylation of the 90 kDa heat shock protein not associated with estradiol receptor in MCF-7 cells in culture.

  1990cites this paper
• Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family.

  1990cites this paper
• Purification of Drosophila hsp 83 and immunoelectron microscopic localization.

  1990cites this paper
• Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer.

  1990cites this paper