Tumor Necrosis Factor- (cid:1) Supports the Survival of Osteoclasts through the Activation of Akt and ERK*

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• Research Progress on the Role and Intervention of the MAPK Signaling Pathway in the Imbalance of Bone Remodeling in Postmenopausal Osteoporosis

  2025cites this paper
• ST1936 stimulates osteoclastogenesis and suppresses osteoclastic apoptosis through the ERK1/2 signaling pathway in bone marrow-derived macrophages.

  2025cites this paper
• Impact of HCV cure on systemic inflammation and bone density, quality, and turnover

  2025cites this paper
• Abnormal Trabecular and Cortical Bone Microarchitecture in Chronic Hepatitis C Infection and Associations With Select Inflammatory Cytokines

  2025cites this paper
• Changes in Bone Microarchitecture and Inflammatory Cytokines After Cure of Chronic Hepatitis C Infection With Direct-Acting Antiviral Therapy

  2025cites this paper
• 4-Hydroxyphenylacetic Acid, a microbial-derived metabolite of Polyphenols, inhibits osteoclastogenesis by inhibiting ROS production.

  2024cites this paper
• Mechanism of action of Salvia miltiorrhiza on avascular necrosis of the femoral head determined by integrated network pharmacology and molecular dynamics simulation

  2024cites this paper
• Reduction of osteoclast formation and survival following suppression of cytokines by diacerein in periodontitis.

  2024cites this paper
• Isoimperatorin attenuates bone loss by inhibiting the binding of RANKL to RANK.

  2023cites this paper
• Extracellular Signal-Regulated Kinases Play Essential but Contrasting Roles in Osteoclast Differentiation

  2023cites this paper
• TNFR1 signaling is positively regulated by Jak-2 and c-Src via tyrosine phosphorylation

  2023cites this paper
• Extracellular Prdx1 mediates bacterial infection and inflammatory bone diseases.

  2023cites this paper
• Lonafarnib Inhibits Farnesyltransferase via Suppressing ERK Signaling Pathway to Prevent Osteoclastogenesis in Titanium Particle-Induced Osteolysis

  2022cites this paper
• The Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Pathway in Osteoblasts

  2022cites this paper
• Role of the Interaction of Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors 1 and 2 in Bone-Related Cells

  2022cites this paper
• Network-Based Pharmacology and Bioinformatics Study on the Mechanism of Action of Gujiansan in the Treatment of Steroid-Induced Avascular Necrosis of the Femoral Head

  2022cites this paper
• Lipopolysaccharide-Preconditioned Dental Follicle Stem Cells Derived Small Extracellular Vesicles Treating Periodontitis via Reactive Oxygen Species/Mitogen-Activated Protein Kinase Signaling-Mediated Antioxidant Effect

  2022cites this paper
• Leukemia/lymphoma-related factor (LRF) or osteoclast zinc finger protein (OCZF) overexpression promotes osteoclast survival by increasing Bcl-xl mRNA: A novel regulatory mechanism mediated by the RNA binding protein SAM68

  2022cites this paper
• 12-Deoxyphorbol-13-Hexadecanoate Abrogates OVX-Induced Bone Loss in Mice and Osteoclastogenesis via Inhibiting ROS Level and Regulating RANKL-Mediated NFATc1 Activation

  2022cites this paper
• DDDT_A_328238 4811..4825

  2021cites this paper
• Effect of TNF inhibitors with bisphosphonates vs bisphosphonates alone on bone mineral density and bone and cartilage biomarkers at 1 year in patients with rheumatoid arthritis: A prospective study.

  2021cites this paper
• Notopterol Attenuates Estrogen Deficiency-Induced Osteoporosis via Repressing RANKL Signaling and Reactive Oxygen Species

  2021cites this paper
• Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis

  2021cites this paper
• Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity

  2021cites this paper
• Multiple versus Solitary Giant Cell Lesions of the Jaw: Similar or Distinct Entities?

  2021cites this paper
• New Insights Into Osteoclast Biology

  2021cites this paper
• Suppression of osteoclastogenesis signalling pathways and attenuation of ameloblastic osteolysis induced by local administration of CaP-bisphosphonate and CaP-doxycycline cements: Review of the literature and therapeutic hypothesis

  2021cites this paper
• TNF is a homoeostatic regulator of distinct epigenetically primed human osteoclast precursors

  2021cites this paper
• SIS3 Suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species.

  2021cites this paper
• The Role of MCU Expression Regulation in Pathogenesis

  2020cites this paper
• Kirenol inhibits RANKL-induced osteoclastogenesis and prevents ovariectomized-induced osteoporosis via suppressing the Ca2+-NFATc1 and Cav-1 signaling pathways.

  2020cites this paper
• Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis

  2020cites this paper
• Vitamin C Deficiency and the Risk of Osteoporosis in Patients with an Inflammatory Bowel Disease

  2020cites this paper
• Overexpression of c‐Fos reverses osteoprotegerin‐mediated suppression of osteoclastogenesis by increasing the Beclin1‐induced autophagy

  2020cites this paper
• Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis Clinical Interventions in Aging

  2020cites this paper
• The Tumor Microenvironment and Immunotherapy in Prostate and Bladder Cancer.

  2020cites this paper
• Inhibitory effects of biochanin A on titanium particle‐induced osteoclast activation and inflammatory bone resorption via NF‐κB and MAPK pathways

  2020cites this paper
• Mucosal Vaccination with UV-Inactivated Chlamydia suis in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ+ Effector Memory Cells

  2020cites this paper
• CIA_A_254885 1201..1212

  2020cites this paper
• The alarmin S100A9 hampers osteoclast differentiation from human circulating precursors by reducing the expression of RANK

  2019cites this paper
• Protease-Activated Receptor 1 Deletion Causes Enhanced Osteoclastogenesis in Response to Inflammatory Signals through a Notch2-Dependent Mechanism

  2019cites this paper
• Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

  2019cites this paper
• Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption

  2019cites this paper
• RANKL-induced osteoclastogenesis in bone marrow-derived macrophages is suppressed by cisapride.

  2019cites this paper
• Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species

  2019cites this paper
• MicroRNA‐1225 activates Keap1‐Nrf2‐HO‐1 signalling to inhibit TNFα‐induced osteoclastogenesis by mediating ROS generation

  2019cites this paper
• Sirtuin 1 inhibits TNF-α-mediated osteoclastogenesis of bone marrow-derived macrophages through both ROS generation and TRPV1 activation

  2018cites this paper
• Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR

  2018cites this paper
• Pentosan polysulfate : an effective treatment for model of rheumatoid arthritis and a novel candidate for inhibition of cytokines-induced osteoclastogenesis

  2018cites this paper
• Roles of Mitogen-Activated Protein Kinases in Osteoclast Biology

  2018cites this paper
• BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway.

  2018cites this paper
• A Novel Synthesized Sulfonamido-Based Gallate-JEZTC Blocks Cartilage Degradation on Rabbit Model of Osteoarthritis: An in Vitro and in Vivo Study

  2018cites this paper
• Boldine Ameliorates Estrogen Deficiency-Induced Bone Loss via Inhibiting Bone Resorption

  2018cites this paper
• RANKL regulates RAW 264 . 7 cell osteoclastogenesis in a manner

  2017cites this paper
• Meclizine Prevents Ovariectomy-Induced Bone Loss and Inhibits Osteoclastogenesis Partially by Upregulating PXR

  2017cites this paper
• Macrolactin F inhibits RANKL‐mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP‐2/smad/Akt/Runx2 signaling pathway

  2017cites this paper
• Chronological differential effects of pro-inflammatory cytokines on RANKL-induced osteoclast differentiation of canine bone marrow-derived macrophages

  2017cites this paper
• Tumor Necrosis Factor Alpha Promotes Osteoclast Formation Via PI3K/Akt Pathway‐Mediated Blimp1 Expression Upregulation

  2017cites this paper
• Matrix Metalloproteinases in Bone Resorption, Remodeling, and Repair.

  2017cites this paper
• Hepatitis C virus coinfection as a risk factor for osteoporosis and fracture

  2016cites this paper
• Tumor necrosis factor alpha promotes osteoclast formation via PI 3 K / Akt pathway-mediated Blimp 1 expression upregulation † Running head : Role of Blimp 1 in TNF-α-induced OCs formation

  2016cites this paper
• A 1-year prospective study of the effect of infliximab on bone metabolism in inflammatory bowel disease patients

  2016cites this paper
• Alteration of Homeostasis in Pre-osteoclasts Induced by Aggregatibacter actinomycetemcomitans CDT

  2016cites this paper
• A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response

  2016cites this paper
• Biologics in Staphylococcus aureus arthritis

  2016cites this paper
• Alexidine dihydrochloride and Thonzonium bromide: Novel Modulators of Osteoclast Formation & Function

  2016cites this paper
• Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling

  2016cites this paper
• Structural Bone Deficits in HIV/HCV-Coinfected, HCV-Monoinfected, and HIV-Monoinfected Women.

  2015cites this paper
• Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside—a Comprehensive Review

  2015cites this paper
• articleInhibitory effects of ZSTK 474 , a novel phosphoinositide 3-kinase inhibitor , on osteoclasts and collagen-induced arthritis in mice

  2015influential citation
• Overexpression of prohibitin-1 inhibits RANKL-induced activation of p38-Elk-1-SRE signaling axis blocking MKK6 activity.

  2015cites this paper
• Role of AZI 2 in osteoclastogenesis 1 5-azacytidine-induced protein 2 ( AZI 2 ) regulates bone mass by fine-tuning osteoclast survival

  2015cites this paper
• 5-Azacytidine-induced Protein 2 (AZI2) Regulates Bone Mass by Fine-tuning Osteoclast Survival*

  2015cites this paper
• : the effects of antitumour necrosis factor-α on bone metabolism in inflammatory bowel disease

  2015cites this paper
• Mutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function*

  2015cites this paper
• TNF-α Suppressed FSH-Induced LH Receptor Expression Through Transcriptional Regulation in Rat Granulosa Cells.

  2015cites this paper
• Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways.

  2015cites this paper
• Smoking Modulates Gene Expression of Type I Collagen, Bone Sialoprotein, and Osteocalcin in Human Alveolar Bone.

  2015cites this paper
• Epoxyeicosanoids suppress osteoclastogenesis and prevent ovariectomy‐induced bone loss

  2015cites this paper
• "This is the pre-peer reviewed version of the following article: Review article: the effects of antitumour necrosis factor-α on bone metabolism in inflammatory bowel

  2015cites this paper
• Sphingolipid metabolism and its role in the skeletal tissues

  2015cites this paper
• Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survival.

  2014cites this paper
• Apigenin inhibits TGF‐β‐induced VEGF expression in human prostate carcinoma cells via a Smad2/3‐ and Src‐dependent mechanism

  2014cites this paper
• SH3BP2 Cherubism Mutation Potentiates TNF‐α–Induced Osteoclastogenesis via NFATc1 and TNF‐α–Mediated Inflammatory Bone Loss

  2014cites this paper
• Nrf2 is a novel regulator of bone acquisition.

  2014cites this paper
• Relationship between Serum Levels of Tau Fragments and Clinical Progression of Alzheimer's Disease

  2014cites this paper
• Tartrate‐resistant acid phosphatase 5b is a potential biomarker for rheumatoid arthritis: a pilot study in Han Chinese

  2014cites this paper
• HSP27 phosphorylation modulates TRAIL-induced activation of Src-Akt/ERK signaling through interaction with β-arrestin2.

  2014cites this paper
• Modulation of osteoclast differentiation and bone resorption by Rho GTPases

  2014cites this paper
• Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells

  2014cites this paper
• Prostaglandin D(2) induces apoptosis of human osteoclasts through ERK1/2 and Akt signaling pathways.

  2014influential citation
• Spica Prunella extract inhibits phosphorylation of JNK, ERK and IκBα signals during osteoclastogenesis

  2013cites this paper
• Effect of therapeutic interventions on skeletal growth & development in paediatric inflammatory bowel disease

  2013cites this paper
• Osteoclasts: New Insights

  2013cites this paper
• Targeting Tumor Angiogenesis

  2013cites this paper
• Changes in Vitamin D and Parathyroid Hormone Metabolism in Incident Pediatric Crohn's Disease

  2013cites this paper
• Dependent on High Levels of Acid and Akt in Human Alveolar Macrophages is Cooperative Prosurvival Activity by ERK

  2013cites this paper
• Bone Health in Pediatric Inflammatory Bowel Disease

  2013cites this paper
• Fibrinogen promotes resorption of chitosan by human osteoclasts.

  2013cites this paper
• Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management

  2013cites this paper