Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Current Obesity Reports

• Publication date

  2015-09-10

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s13679-015-0176-5PMID 26353882
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The vitamin D receptor.

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• Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-alcoholic fatty liver disease.

  2007cited by this paper
• Vitamin D deficiency.

  2007cited by this paper
• Low 25-hydroxyvitamin D concentrations in obese women: Their clinical significance and relationship with anthropometric and body composition variables

  2007influential reference
• Vitamin D decreases NFkappaB activity by increasing IkappaBalpha levels.

  2006cited by this paper
• Vitamin D decreases NFB activity by increasing IB levels

  2006cited by this paper
• Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells.

  2006cited by this paper
• Complex Role of the Vitamin D Receptor and Its Ligand in Adipogenesis in 3T3-L1 Cells*

  2006cited by this paper
• Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial.

  2006cited by this paper
• Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases.

  2006cited by this paper
• Inflammation and metabolic disorders

  2006cited by this paper

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• The impact of obesity on bone health: molecular pathways, metabolic interactions, and associated pathologies

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• Sex-Specific Association Between Serum VitaminD and Health Status Among Chinese Obesity People: A Cross-Sectional Study

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  2024cites this paper
• Efficacy of L-cysteine in increasing circulatory hydrogen sulfide, nitrite, and 25(OH)VD levels in ZDF rats and in vitro treatment of H2S and NO2 in upregulating VD hydroxylase genes in monocytes.

  2024cites this paper
• Advances in biomedical applications of vitamin D for VDR targeted management of obesity and cancer.

  2024cites this paper
• Untargeted metabolomics reveal signatures of a healthy lifestyle

  2024cites this paper
• Vitamin D levels in a population from Argentina with metabolic disorders

  2022cites this paper
• Alterations of liver enzymes and lipid profile in response to exhaustive eccentric exercise: vitamin D supplementation trial in overweight females with non-alcoholic fatty liver disease

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• Very low calorie ketogenic diet combined with physical interval training for preserving muscle mass during weight loss in sarcopenic obesity: A pilot study

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  2021cites this paper
• DMSO_A_285597 525..534

  2021cites this paper
• Vitamin D Deficiency Is Inversely Associated with Homeostatic Model Assessment of Insulin Resistance

  2021cites this paper
• Impact of Vitamin D Supplementation on Inflammatory Markers’ Levels in Obese Patients

  2021cites this paper
• Vitamin D supplementation and energy and metabolic homoeostasis in obese and overweight subjects: a protocol for a systematic review

  2021cites this paper
• To the question of the pathogenetic mechanisms of the influence of obesity on the level of vitamin D

  2021cites this paper
• Associations of physical activity with vitamin D status depends on obesity status in old adults.

  2020cites this paper
• Malnutrition in obesity before and after bariatric surgery.

  2020cites this paper
• Developing the Persian Version of Yale Food Addiction Scale and Assessing Its Psychometric Properties

  2020cites this paper
• Co-treatment with Vitamin D Supplementation and Aerobic Training in Elderly Women with Vit D Deficiency and NAFLD: A Single-blind Controlled Trial

  2020cites this paper
• Bone metabolism in Chinese patients after laparoscopic Roux-en-Y gastric bypass

  2020cites this paper
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  2020cites this paper
• Vitamin D in pregnancy and infancy : dietary sources and associations with pregnancy outcomes and infant growth

  2019cites this paper
• Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.

  2019cites this paper
• Vitamin D Is Inversely Related to Obesity: Cross-Sectional Study in a Small Cohort of Serbian Adults

  2019cites this paper
• A preliminary transcriptome analysis suggests a transitory effect of vitamin D on mitochondrial function in obese young Finnish subjects

  2019cites this paper
• Review of the potential health effects of light and environmental exposures in underground workplaces

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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