TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts

K. Helmke,R. Heald

Published 2014 in Journal of Cell Biology

ABSTRACT

TPX2 levels modulate spindle architecture through Eg5, partitioning microtubules between a tiled, antiparallel array that promotes spindle expansion and a cross-linked, parallel architecture that concentrates microtubules at spindle poles.

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