Opiate receptor binding sites in human spinal cord.

No abstract is available for this paper.

• Publication year

  1983

• Venue

  Brain Research

• Publication date

  1983-05-16

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0006-8993(83)90897-1PMID 6307472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization and localization of immunoreactive dynorphin, alpha-neo-endorphin, Met-enkephalin and substance P in human spinal cord.

  1983cited by this paper
• Dynorphin1–8 and dynorphin1–9 are ligands for the κ-subtype of opiate    receptor

  1982cited by this paper
• Benzomorphan binding sites in rat lumbo-sacral spinal cord.

  1982cited by this paper
• Dynorphin and dynorphin are ligands for the kappa-subtype of opiate receptor.

  1982cited by this paper
• Dynorphin is a specific endogenous ligand of the kappa opioid receptor.

  1982cited by this paper
• In vivo evidence for multiple opiate receptors mediating analgesia in the rat spinal cord.

  1982cited by this paper
• Opiate receptor binding sites in human brain.

  1982cited by this paper
• Immunoreactive dynorphin in human brain and pituitary.

  1982cited by this paper
• OPIATE BINDING SITES IN THE LUMBO-SACRAL SPINAL CORD FROM VARIOUS SPECIES

  1981cited by this paper
• Novel opiate binding sites selective for benzomorphan drugs

  1981cited by this paper
• Analogues of beta-LPH61-64 possessing selective agonist activity at mu-opiate receptors.

  1981cited by this paper
• Novel opiate binding sites selective for benzomorphan drugs.

  1981cited by this paper
• The influence of foot-shock stress upon brain, pituitary and spinal cord pools of immunoreactive dynorphin in rats.

  1981cited by this paper
• Human spinal neurons: Innervation by both substance p and enkephalin

  1981cited by this paper
• Immunoreactive dynorphin in mammalian spinal cord and dorsal root ganglia.

  1981cited by this paper
• Human spinal neurons: innervation by both substance P and enkephalin.

  1981cited by this paper
• A subclassification of κ-sites in human brain by use of dynorphin 1–17

  1981cited by this paper
• Analogues of β-LPH61–64 posessing selective agonist activity at μ-opiate receptors

  1981cited by this paper
• Highly specific opiate receptors for dynorphin-(1-13) in the mouse vas deferens.

  1980cited by this paper
• Multiple opiate receptor sites on primary afferent fibres

  1980cited by this paper
• Ligand: a versatile computerized approach for characterization of ligand-binding systems.

  1980cited by this paper
• Opiate receptors in rat spinal cord

  1980cited by this paper
• Regional distribution of methionine-enkephalin- and beta-endorphin-like immunoreactivity in human brain and pituitary.

  1979cited by this paper
• Immunohistochemical localization of enkephalin in rat brain and spinal cord

  1978cited by this paper
• Interaction of enkephalin with opiate receptors in intact cultured cells.

  1978cited by this paper
• Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

  1977cited by this paper
• Structural, electrophysiological, biochemical, and pharmacological properties of neuroblastoma-glioma cell hybrids in cell culture.

  1977cited by this paper
• Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla.

  1977cited by this paper
• The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat.

  1976cited by this paper

• [11C]Carfentanil PET Whole-Body Imaging of μ-Opioid Receptors: A First in-Human Study

  2025cites this paper
• The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord.

  2018cites this paper
• The effect of µ-opioid receptor activation on GABAergic neurons in the spinal dorsal horn

  2018cites this paper
• Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research

  2015cites this paper
• Neuropeptide Receptors in Pain Circuitries: Useful Targets for CNS Imaging with Non-Peptide Ligands Suitable for PET?

  2014cites this paper
• UMB-3, a novel rabbit monoclonal antibody, for assessing μ-opioid receptor expression in mouse, rat and human formalin-fixed and paraffin-embedded tissues.

  2011cites this paper
• Opioidnachweis durch Bedsidetests order Sticks

  2010cites this paper
• Evidence for the involvement of MC4 receptors in the central mechanisms of opioid antinociception

  2005cites this paper
• Der opiatabhängige Patient

  2004cites this paper
• Functional Organization of Dorsal Horn Interneurons

  2004cites this paper
• Opiatentzug in Narkose

  2004cites this paper
• Is the cutaneous silent period an opiate‐sensitive nociceptive reflex?

  2002cites this paper
• Endogene Opioide (Endorphine, Enkephaline)

  2002cites this paper
• Exorphine (exogene Opioidpeptide) und β-Casomorphine

  2002cites this paper
• A novel acetylated analogue of dynorphin A-(1-11) amide as a κ-opioid receptor antagonist

  1999cites this paper
• A novel acetylated analogue of dynorphin A-(1-11) amide as a kappa-opioid receptor antagonist.

  1999cites this paper
• [Pain therapy in tumor patients and in palliative medicine. 2: Invasive measures].

  1998cites this paper
• Synergistic antinociceptive interaction between sevoflurane and intrathecal fentanyl in dogs.

  1998cites this paper
• SCHMERZTHERAPIE BEI TUMORPATIENTEN UND IN DER PALLIATIVMEDIZIN. TEIL 2: INVASIVE VERFAHREN

  1998cites this paper
• Differential antinociceptive effects of spinal opioids on foot withdrawal responses evoked by C fibre or A delta nociceptor activation.

  1997cites this paper
• Differential antinociceptive effects of spinal opioids on foot withdrawal responses evoked by C fibre or Aδ nociceptor activation

  1997cites this paper
• Antinociceptive effects of the kappa-opioid receptor agonist RP 60180 compared with pentazocine in an experimental human pain model.

  1997cites this paper
• Changes of opioid binding density in the rat spinal cord following unilateral dorsal rhizotomy.

  1995cites this paper
• Opioid receptors in the superficial layers of the rat spinal cord: functional implications in pain processing.

  1995cites this paper
• Signal Transduction of Opiate Receptors in Spinal Cord Cells

  1994cites this paper
• Mu-, delta-, kappa-opioid receptors and their subtypes. A critical review with emphasis on radioligand binding experiments.

  1994cites this paper
• Autoradiographic localization of receptors for neuropeptide FF, FLFQPQRFamide, in human spinal sensory system.

  1994cites this paper
• 3H-naloxone binding in brain regions of normotensive Wistar, spontaneously hypertensive and renal hypertensive rats.

  1994cites this paper
• Pharmacological characterization of dynorphin A (1-17)-induced effects on spinal cord-evoked potentials.

  1994cites this paper
• Effect of ICI197067, a κ-opioid receptor agonist, spinally on Aδ and C reflexes and intracerebrally on respiration

  1993cites this paper
• Effect of ICI197067, a kappa-opioid receptor agonist, spinally on A delta and C reflexes and intracerebrally on respiration.

  1993cites this paper
• Differential effects of alfentanil, fentanyl, pethidine and lignocaine administered intrathecally on nociceptive responses evoked by low and high frequency stimulation of somatic nerves.

  1993cites this paper
• Role of Endogenous Opioids and Opioid Receptors in Central Nervous System Injury

  1993cites this paper
• Involvement of supraspinal epsilon and mu opioid receptors in inhibition of the tail-flick response induced by etorphine in the mouse.

  1992cites this paper
• Morphine blocks descending pain inhibitory controls in humans

  1992cites this paper
• The presence and actions of opioid receptors in bovine pineal gland

  1992influential citation
• Characterization of opioid binding sites in rat spinal cord.

  1992cites this paper
• N-methyl-D-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies.

  1992cites this paper
• Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides.

  1992cites this paper
• Influence of opioids on substance P release evoked by antidromic stimulation of primary afferent fibers in the hind instep of rats.

  1992cites this paper
• Biochemical characterization and regional quantification of mu, delta and kappa opioid binding sites in rat spinal cord.

  1991cites this paper
• Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord

  1991cites this paper
• Effects of commonly used analgesics and Antiinflammatory drugs, in acute and chronic Pain in the naked mole-rat (heterocephalus Glaber) using the formalin test

  1991cites this paper
• Receptors in the Human Spinal Cord

  1991cites this paper
• Pharmacology of spinal peptides affecting sensory and motor functions: dynorphins, somatostatins and tachykinins.

  1991cites this paper
• Central analgesic mechanisms: a review of opioid receptor physiopharmacology and related antinociceptive systems.

  1991cites this paper
• High resolution radioautographic localization of [125I]FK-33-824-labelled mu opioid receptors in the spinal cord of normal and deafferented rats.

  1991cites this paper
• Autoradiographic distribution of mu, delta and kappa opioid binding sites in the superficial dorsal horn, over the rostrocaudal axis of the rat spinal cord.

  1991cites this paper
• Dynorphin-induced depression of the dorsal root potential in rat spinal cord: a possible mechanism for potentiation of the C-fiber reflex.

  1991cites this paper
• Autoradiographic distribution of μ, δ and κ opioid binding sites in the superficial dorsal horn, over the rostrocaudal axis of the rat spinal cord

  1991cites this paper
• Pre- and postsynaptic distribution of μ, δ and κ opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord

  1990cites this paper
• δ‐Opioid receptor binding sites in rodent spinal cord

  1990cites this paper
• Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord.

  1990cites this paper
• Pre- and postnatal development of opiate receptor subtypes in rat spinal cord.

  1990cites this paper
• Characterization of κ opiate receptors in rat spinal cord—dorsal root ganglion cocultures and their regulation by chronic opiate treatment

  1990cites this paper
• Dynorphin A-(1-17) induces alterations in free fatty acids, excitatory amino acids, and motor function through an opiate-receptor-mediated mechanism

  1990cites this paper
• Opioids and opioid receptors mediating antinociception at various levels of the neuraxis.

  1990cites this paper
• Pharmacology of spinal opioids.

  1990cites this paper
• Quantitative analysis of multiple kappa-opioid receptors by selective and nonselective ligand binding in guinea pig spinal cord: resolution of high and low affinity states of the kappa 2 receptors by a computerized model-fitting technique.

  1990cites this paper
• Opioid and nonopioid mechanisms may contribute to dynorphin's pathophysiological actions in spinal cord injury

  1990cites this paper
• Monoclonal antibodies against the S2‐serotonin receptor from rat brain that cross‐react with dopamine and opiate receptors

  1989cites this paper
• Endorphins in male impotence: evidence for naltrexone stimulation of erectile activity in patient therapy.

  1989cites this paper
• Regulation of Calcium Channels and Adenylate Cyclase by Opiates

  1989cites this paper
• Induction of the gene encoding pro-dynorphin by experimentally induced arthritis enhances staining for dynorphin in the spinal cord of rats.

  1989cites this paper
• Spinal antinociceptive actions and naloxone reversibility of intravenous μ‐ and κ‐opioids in spinalized rats: potency mismatch with values reported for spinal administration

  1989cites this paper
• Effects of cervical spinal hemisection on dihydromorphine binding in brainstem and spinal cord in cat.

  1989cites this paper
• Opioid Receptors in the Dorsal Horn of Intact and Deafferented Rats: Autoradiographic and Electrophysiological Studies

  1989cites this paper
• [Participation of opioids and opioid receptors in antinociception at various levels of the nervous system].

  1989cites this paper
• On the Influence of Anaesthesia, Stimulus Intensity and Drug Access in Pharmacological Tests of Sensory Processing in the Superficial Dorsal Horn

  1989cites this paper
• Ontogeny of mu and delta opioid receptors and of neutral endopeptidase in human spinal cord: an autoradiographic study.

  1989cites this paper
• Kappa opiate agonists inhibit Ca2+ influx in rat spinal cord-dorsal root ganglion cocultures. Involvement of a GTP-binding protein.

  1989cites this paper
• Characterisation of κ-opioid binding sites in rat and guinea-pig spinal cord

  1989cites this paper
• Effect of repeated administration of U-50,488H, a kappa opioid receptor agonist, on central 5-HT1 and 5-HT2 receptors in the rat.

  1989cites this paper
• Characterisation of kappa-opioid binding sites in rat and guinea-pig spinal cord.

  1989cites this paper
• Spinal Pharmacology of Agents which Alter Pain Transmission and Muscle Tone

  1988cites this paper
• Local-spinal Therapy of Spasticity

  1988cites this paper
• Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat.

  1988cites this paper
• CSF morphine levels after lumbar intrathecal administration of isobaric and hyperbaric solutions for cancer pain

  1988cites this paper
• Influence of dynorphin (1-13) on spinal reflexes in the rat.

  1988cites this paper
• Central Actions of Opiates and Opioid Peptides

  1988cites this paper
• Opioid antinociception in amphibians.

  1988cites this paper
• Modulation of adenylate cyclase activity of mouse spinal cord-ganglion explants by opioids, serotonin and pertussis toxin.

  1988cites this paper
• Effects of opioids on the heat stimulus-evoked substance P release and thermal edema in the rat hind paw.

  1988cites this paper
• Response

  1987cites this paper
• Distribution of opioid binding sites in spinal cord.

  1987cites this paper
• Opiate receptors in the human spinal cord: a detailed anatomical study comparing the autoradiographic localization of [3H]diprenorphine binding sites with the laminar pattern of substance P, myelin and nissl staining.

  1987cites this paper
• Distinct distribution of opioid receptor types in rat lumbar spinal cord

  1987cites this paper
• Subtraction autoradiography of opiate receptor subtypes in human brain.

  1987cites this paper
• Opiates, opioids and their receptors in the modulation of pain.

  1987cites this paper
• Spinal opiates: a review of their effect on spinal function with emphasis on pain processing

  1987cites this paper
• Opioid receptor binding in rat spinal cord

  1987influential citation
• κ-Selective Opiate Antagonist Nor-Binaltorphimine Improves Outcome After Traumatic Spinal Cord Injury in Rats

  1987cites this paper
• Morphine- and ketocyclazocine-induced analgesia in the developing rat: differences due to type of noxious stimulus and body topography.

  1987cites this paper
• Opioid ligand binding sites in the spinal cord of the guinea-pig.

  1986cites this paper
• Effects of opioids and opioid peptide on the release of substance P-like material induced by tooth pulp stimulation in the trigeminal nucleus caudalis of the rabbit.

  1986cites this paper
• Pharmacology of delta-opioid receptors in the hamster vas deferens.

  1986cites this paper
• In vivo evidence for spinal delta-opiate receptor operated antinociception.

  1986cites this paper
• Kappa opioid receptors in human lumbo-sacral spinal cord.

  1986cites this paper
• Pharmacology of δ-opioid receptor in the hamster vas deferens

  1986cites this paper
• A model of chronic pain in the rat: response of multiple opioid systems to adjuvant-induced arthritis

  1986influential citation