Uncovering Orthologous Genes of the Ciona Intestinalis Fanconi Anemia Pathway

Fanconi Anemia is a disease caused by any number of mutations in a collection of DNA double-strand repair genes. In silico tests were performed to determine whether any of these genes were conserved in Ciona, which split from humans over 500 million years ago. Among the 22 gene products tested, evidence for 10 orthologs were discovered. Possible orthologs were seen in all three of the major groups of FA proteins.

• Publication year

  2015

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.23860/thesis-stanley-edward-2015
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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