Frailty, Inflammation, and Mortality Among Persons Aging With HIV Infection and Injection Drug Use.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  The journals of gerontology. Series A, Biological sciences and medical sciences

• Publication date

  2015-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/gerona/glv107PMID 26386010PMCID PMC4643614
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers.

  2015cited by this paper
• Oxidative stress markers and all-cause mortality at older age: a population-based cohort study.

  2015cited by this paper
• Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.

  2014cited by this paper
• Do changes in circulating biomarkers track with each other and with functional changes in older adults?

  2014cited by this paper
• Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men.

  2014cited by this paper
• Can early therapy reduce inflammation?

  2014cited by this paper
• The "cytokine for gerontologists" has some company.

  2014cited by this paper
• Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults.

  2014influential reference
• Inflammatory Co-morbidities in HIV+ Individuals: Learning Lessons from Healthy Ageing

  2014cited by this paper
• Is HIV a model of accelerated or accentuated aging?

  2014cited by this paper
• Biologic aging, frailty, and age-related disease in chronic HIV infection.

  2014cited by this paper
• Frailty as a Novel Predictor of Mortality and Hospitalization in Individuals of All Ages Undergoing Hemodialysis

  2013cited by this paper
• Longitudinal changes in engagement in care and viral suppression for HIV-infected injection drug users

  2013cited by this paper
• Correlates of Elevated Interleukin-6 and C-Reactive Protein in Persons With or at High Risk for HCV and HIV Infections

  2013cited by this paper
• Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada

  2013cited by this paper
• Frailty, HIV Infection, and Mortality in an Aging Cohort of Injection Drug Users

  2013influential reference
• Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy.

  2013cited by this paper
• Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy.

  2013cited by this paper
• Frailty in HIV-Infected Adults in South Africa

  2013cited by this paper
• Comparison of Functional Status Instruments in HIV-Infected Adults on Effective Antiretroviral Therapy

  2012cited by this paper
• HIV and aging--preparing for the challenges ahead.

  2012cited by this paper
• HIV and Aging: State of Knowledge and Areas of Critical Need for Research. A Report to the NIH Office of AIDS Research by the HIV and Aging Working Group

  2012cited by this paper
• Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.

  2012cited by this paper
• The influence of sex, race/ethnicity, and educational attainment on human immunodeficiency virus death rates among adults, 1993-2007.

  2012cited by this paper
• HIV infection, inflammation, immunosenescence, and aging.

  2011cited by this paper
• The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection.

  2011cited by this paper
• HIV infection, immune suppression, and uncontrolled viremia are associated with increased multimorbidity among aging injection drug users.

  2011cited by this paper
• Premature age-related comorbidities among HIV-infected persons compared with the general population.

  2011cited by this paper
• Inflammatory markers in population studies of aging.

  2011influential reference
• HIV infection in the etiology of lung cancer: confounding, causality, and consequences.

  2011cited by this paper
• The biology of aging and frailty.

  2011cited by this paper
• The frailty syndrome: definition and natural history.

  2011cited by this paper
• Nonstructured Treatment Interruptions Among Injection Drug Users in Baltimore, MD

  2009cited by this paper
• Frailty among HIV-infected persons in an urban outpatient care setting.

  2009cited by this paper
• Total and cause-specific mortality in the cardiovascular health study.

  2009cited by this paper
• Inflammation and frailty measures in older people

  2009cited by this paper
• Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

  2008cited by this paper
• HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty.

  2007cited by this paper
• Inflammation and Frailty in Older Women

  2007cited by this paper
• Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults

  2006cited by this paper
• Phenotype of frailty: characterization in the women's health and aging studies.

  2006cited by this paper
• Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care.

  2004cited by this paper
• Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study.

  2003cited by this paper
• Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study.

  2002cited by this paper
• Frailty in older adults: evidence for a phenotype.

  2001cited by this paper
• The Alive Study: A Longitudinal Study of HIV-1 Infection in Intravenous Drug Users: Description of Methods

  1991cited by this paper

• The Prevalence and Influencing Factors of Frailty Among Middle‐Aged and Older Adults With HIV/AIDS From a Global Perspective: A Systematic Review and Meta‐Analysis

  2026cites this paper
• Inflammation in frailty, cognitive impairment, clinical events, and mortality among older adults with HIV in the ACTG HAILO cohort

  2025cites this paper
• The association of methadone use with physical function and frailty among persons who inject drugs.

  2025cites this paper
• Cognitive function and mortality among persons aging with HIV and injection drug use.

  2025cites this paper
• Long-term smoking contributes to aging frailty and inflammatory response

  2025cites this paper
• Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment

  2024cites this paper
• Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study

  2024cites this paper
• Changes to inflammatory markers during 5 years of viral suppression and during viral blips in people with HIV initiating different integrase inhibitor based regimens

  2024cites this paper
• Biomarkers of microbial translocation and generalized inflammation are associated with frailty among people with HIV

  2024cites this paper
• Accelerated aging in people living with HIV: The neuroimmune feedback model

  2024cites this paper
• Muscle Quality And Physical Function In Men With And Without Hiv.

  2024cites this paper
• Inflammatory markers and physical frailty: towards clinical application

  2024cites this paper
• Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV

  2023cites this paper
• Accumulation of immune-suppressive CD4 + T cells in aging - tempering inflammaging at the expense of immunity.

  2023cites this paper
• Geriatric syndromes, chronic inflammation, and advances in the management of frailty: A review with new insights.

  2023cites this paper
• Frailty and prefrailty phenotypes increase the odds of abnormal cognitive impairment screens in people with HIV

  2023cites this paper
• Inflammatory biomarkers in older adults with frailty: a systematic review and meta-analysis of cross-sectional studies

  2022cites this paper
• Interaction between sleep quality and dietary inflammation on frailty: NHANES 2005-2008.

  2022cites this paper
• Frailty in older people living with HIV: current status and clinical management

  2022cites this paper
• Heroin use is associated with vascular inflammation in HIV.

  2022cites this paper
• Frailty and Cytokines in Preclinical Models: Comparisons With Humans.

  2022cites this paper
• Physiological Systems in Promoting Frailty.

  2022cites this paper
• SHBG, bone mineral density and physical function among injection drug users with and without HIV and HCV.

  2022cites this paper
• Ageing and older people who use illicit opioids, cocaine or methamphetamine: a scoping review and literature map

  2022cites this paper
• Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases

  2022cites this paper
• Impact of Heroin and HIV on Gut Integrity and Immune Activation

  2022cites this paper
• Frailty and HIV: Moving from Characterization to Intervention

  2021cites this paper
• Mortality among persons who inject drugs: A prospective cohort followed over three decades in Baltimore, Maryland, USA.

  2021cites this paper
• Muscle, endocrine, and immunological markers of frailty in older people.

  2021cites this paper
• Measuring frailty in younger populations: a rapid review of evidence

  2021cites this paper
• Clinical consequences of asymptomatic cytomegalovirus in treated human immunodeficency virus infection

  2021cites this paper
• Incorporating Frailty Into the Pooled Cohort Equations to Predict Cardiovascular Disease Among Persons With HIV

  2021cites this paper
• Association of inflammatory mediators with frailty status in older adults: results from a systematic review and meta-analysis

  2020cites this paper
• Inflammation, Frailty and Cardiovascular Disease.

  2020cites this paper
• Frailty - A promising concept to evaluate disease vulnerability.

  2020cites this paper
• Frailty transitions, inflammation and mortality among persons aging with HIV infection and injection drug use.

  2020cites this paper
• Senotherapeutics and HIV-1 Persistence

  2020cites this paper
• The Gut Microbiome and Frailty.

  2020cites this paper
• Frailty Significantly Associated with a Risk for Mid-term Outcomes in Elderly Chronic Coronary Syndrome Patients: a Prospective Study

  2020cites this paper
• Circulating biomarkers characterizing physical frailty: CRP, hemoglobin, albumin, 25OHD and free testosterone as best biomarkers. Results of a meta-analysis.

  2020cites this paper
• Physical Function Impairment and Frailty in Middle-Aged People Living With Human Immunodeficiency Virus in the REPRIEVE Trial Ancillary Study PREPARE.

  2020cites this paper
• Frequency, Risk Factors, and Mediators of Frailty Transitions During Long-Term Follow-Up Among People With HIV and HIV-Negative AGEhIV Cohort Participants

  2020cites this paper
• Retinol‐binding protein 4 (RBP4), a potential biomarker of frailty in HIV‐infected people on stable antiretroviral therapy

  2019cites this paper
• Association of Fibroblast Growth Factor-23 (FGF-23) With Incident Frailty in HIV-Infected and HIV-Uninfected Individuals

  2019cites this paper
• Frailty is an independent risk factor for mortality, cardiovascular disease, bone disease and diabetes among aging adults with HIV.

  2019cites this paper
• The dynamic association between Frailty, CD4 and CD4/CD8 ratio in people aging with HIV

  2019cites this paper
• Frailty biomarkers in humans and rodents: Current approaches and future advances.

  2019cites this paper
• Frailty phenotype in older people living with HIV: concepts, prevention and issues.

  2019cites this paper
• Interleukin-6 is associated with mortality and neuropsychiatric outcomes in antiretroviral-naïve adults in Rakai, Uganda

  2019cites this paper
• Toll-Like Receptors 2 and 4 Modulate Pulmonary Inflammation and Host Factors Mediated by Outer Membrane Vesicles Derived from Acinetobacter baumannii

  2019cites this paper
• The Opioid Epidemic: Impact on Inflammation and Cardiovascular Disease Risk in HIV

  2019cites this paper
• Tyrosine Kinase Inhibition: a New Perspective in the Fight against HIV

  2019cites this paper
• Senotherapeutics for HIV and aging.

  2019cites this paper
• Aging, sex, inflammation, frailty, and CMV and HIV infections.

  2019cites this paper
• Aging, Health, and Quality of Life for Older People Living With HIV in Sub-Saharan Africa: A Review and Proposed Conceptual Framework

  2019cites this paper
• Envejecimiento y Fragilidad en el paciente con infección por VIH

  2019cites this paper
• Inflammatory Markers and Frailty

  2018cites this paper
• [HIV infection as a cause of accelerated aging and frailty].

  2018cites this paper
• Frailty significantly impairs the short term prognosis in elderly patients with heart failure

  2018cites this paper
• The Relationship Between the Dietary Inflammatory Index and Incident Frailty: A Longitudinal Cohort Study.

  2018cites this paper
• Can Biomarkers Advance HIV Research and Care in the Antiretroviral Therapy Era?

  2018cites this paper
• Association between the Dietary Inflammatory Index and Risk of Frailty in Older Individuals with Poor Nutritional Status

  2018cites this paper
• Derivation and internal validation of a mortality risk index for aged people living with HIV: The Dat'AIDS score

  2018cites this paper
• Frailty, Inflammatory Markers, and Waitlist Mortality Among Patients With End-stage Renal Disease in a Prospective Cohort Study

  2018cites this paper
• Abdominal obesity, sarcopenia, and osteoporosis are associated with frailty in men living with and without HIV

  2018cites this paper
• Frailty Screening and Interventions: Considerations for Clinical Practice.

  2018cites this paper
• The Role of Mitochondrial DNA Variation in Age-Related Decline in Gait Speed Among Older Men Living With Human Immunodeficiency Virus

  2018cites this paper
• Geriatric-HIV Medicine: the geriatrician’s role

  2018cites this paper
• Inflammation Strikes Again: Frailty and HIV

  2018cites this paper
• Frailty prevalence and predictors in older adults with HIV

  2017influential citation
• Learning to Age Successfully with HIV

  2017cites this paper
• Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users

  2017cites this paper
• HIV/AIDS in Rural Communities

  2017cites this paper
• Correlates of frailty phenotype and frailty index and their associations with clinical outcomes

  2017cites this paper
• Multimorbidity and Burden of Disease.

  2017cites this paper
• In fl ammation , Immune Activation , Immunosenescence , and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection

  2017cites this paper
• Predictors of transitions in frailty severity and mortality among people aging with HIV

  2017cites this paper
• Inflammation and frailty in the elderly: A systematic review and meta-analysis (vol 31, pg 1, 2016)

  2017cites this paper
• Frailty and Circulating Markers of Inflammation in HIV+ and HIV− Men in the Multicenter AIDS Cohort Study

  2017cites this paper
• Antiretroviral initiation is associated with increased skeletal muscle area and fat content

  2017cites this paper
• Frailty and physical function in older HIV-infected adults

  2017cites this paper
• Redefining Aging in HIV Infection Using Phenotypes

  2017cites this paper
• Systematic Review of Prevalence and Predictors of Frailty in Individuals with Human Immunodeficiency Virus

  2016influential citation
• Frailty has a stronger association with inflammation than age in older veterans

  2016cites this paper
• Inflammation and frailty in the elderly: A systematic review and meta-analysis

  2016influential citation
• Frailty in HIV: Epidemiology, Biology, Measurement, Interventions, and Research Needs

  2016cites this paper
• Inflammation and frailty in the elderly: A systematic review and meta-analysis.

  2016influential citation
• Energetic interventions for healthspan and resiliency with aging.

  2016cites this paper
• Frailty and Cause-Specific Hospitalization Among Persons Aging With HIV Infection and Injection Drug Use

  2016cites this paper
• Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men with or at Risk for HIV

  2016cites this paper
• [Treating HIV disease: back to the patient?]

  2016cites this paper
• F r a i l t y S c r e e n i n g a n d I n t e r v e n t i o n s Considerations for Clinical Practice

  year unknowncites this paper