Impact of genetic diversity of European-type porcine reproductive and respiratory syndrome virus strains on vaccine efficacy.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Vaccine

• Publication date

  2004-10-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.VACCINE.2004.05.008PMID 15474708
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Respiratory tract protection upon challenge of pigs vaccinated with attenuated porcine reproductive and respiratory syndrome virus vaccines.

  2003cited by this paper
• Interaction between Porcine Reproductive-Respiratory Syndrome Virus and Bacterial Endotoxin in the Lungs of Pigs: Potentiation of Cytokine Production and Respiratory Disease

  2003cited by this paper
• Strain specificity of the immune response of pigs following vaccination with various strains of porcine reproductive and respiratory syndrome virus.

  2003influential reference
• Genetic diversity and phylogenetic analysis of glycoprotein 5 of European-type porcine reproductive and respiratory virus strains in Spain.

  2003cited by this paper
• PRRSV infection increases CD14 expression and LPS-binding protein in the lungs: possible mechanism of PRRSV-LPS clinical synergy

  2003cited by this paper
• Short Communication Genetic diversity and phylogenetic analysis of glycoprotein 5 of European-type porcine reproductive and respiratory virus strains in Spain

  2003cited by this paper
• Comparative safety and efficacy of attenuated single-strain and multi-strain vaccines for porcine reproductive and respiratory syndrome.

  2003cited by this paper
• Leptospirose hos svin

  2002cited by this paper
• Porcine reproductive–respiratory syndrome virus infection predisposes pigs for respiratory signs upon exposure to bacterial lipopolysaccharide

  2002cited by this paper
• Identification of radically different variants of porcine reproductive and respiratory syndrome virus in Eastern Europe: towards a common ancestor for European and American viruses.

  2002cited by this paper
• The genetic diversity of European type PRRSV is similar to that of the North American type but is geographically skewed within Europe.

  2002cited by this paper
• A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease.

  2001cited by this paper
• Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs.

  2000cited by this paper
• Genetic variations among PRRSV strains isolated in Italy and in Russia

  2000cited by this paper
• Variations in the major envelope glycoprotein GP5 of Czech strains of porcine reproductive and respiratory syndrome virus.

  2000cited by this paper
• Diagnostic implications of concurrent inoculation with attenuated and virulent strains of porcine reproductive and respiratory syndrome virus.

  1999cited by this paper
• Heterologous challenge with porcine reproductive and respiratory syndrome (PRRS) vaccine virus: no evidence of reactivation of previous European-type PRRS virus infection.

  1999cited by this paper
• Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: correlations with pathogenicity

  1999cited by this paper
• Efficacy of an American and a European serotype PRRSV vaccine after challenge with American and European wild-type strains of the virus.

  1999cited by this paper
• Genomic and antigenic variations of porcine reproductive and respiratory syndrome virus major envelope GP5 glycoprotein.

  1998cited by this paper
• Molecular variation in the nucleoprotein gene (ORF7) of the porcine reproductive and respiratory syndrome virus (PRRSV).

  1998cited by this paper
• Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans?

  1998cited by this paper
• Variation in open reading frames 3, 4 and 7 among porcine reproductive and respiratory syndrome virus isolates in the UK.

  1997cited by this paper
• In vivo replication of porcine reproductive and respiratory syndrome virus in swine alveolar macrophages and change in the cell population in bronchoalveolar lavage fluid after infection.

  1997cited by this paper
• Phylogenetic relationships of european strains of porcine reproductive and respiratory syndrome virus (PRRSV) inferred from DNA sequences of putative ORF-5 and ORF-7 genes.

  1996cited by this paper
• Dual infections of feeder pigs with porcine reproductive and respiratory syndrome virus followed by porcine respiratory coronavirus or swine influenza virus: a clinical and virological study

  1996cited by this paper
• Diagnosis of porcine reproductive and respiratory syndrome using infected alveolar macrophages collected from live pigs.

  1996influential reference
• Porcine reproductive and respiratory syndrome virus (PRRSV): monoclonal antibodies detect common epitopes on two viral proteins of European and U.S. isolates.

  1996cited by this paper
• Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States.

  1996cited by this paper
• Antigenic comparison of Canadian and US isolates of porcine reproductive and respiratory syndrome virus using monoclonal antibodies to the nucleocapsid protein.

  1995cited by this paper
• Failure to Consider the Antigenic Diversity of Porcine Reproductive and Respiratory Syndrome (PRRS) Virus Isolates May Lead to Misdiagnosis

  1995cited by this paper
• Identification of major differences in the nucleocapsid protein genes of a Québec strain and European strains of porcine reproductive and respiratory syndrome virus.

  1994cited by this paper
• Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus.

  1994cited by this paper
• Mystery swine disease in The Netherlands: the isolation of Lelystad virus.

  1991cited by this paper
• Der "Seuchenhafte Spätabort beim Schwein" - ein Beitrag zur Ätiologie des "Porcinen Reproductive and Respiratory Syndrome (PRRS)"

  1991cited by this paper
• A method for bronchoalveolar lavage in live pigs.

  1989cited by this paper

• Experimental efficacy of vaccination of weaned piglets with a modified-live commercial PRRS virus vaccine against the challenge with a Spanish highly virulent PRRSV-1 strain

  2025cites this paper
• Concurrent but consecutive vaccination of modified live PRRSV-1 and PRRSV-2 provides better protection in nursery pigs.

  2025cites this paper
• Efficacy of an intranasally administered live attenuated PRRSV-2 vaccine against challenge with a highly virulent PRRSV-1 strain

  2025cites this paper
• Determination of the frequency of individuals with broadly cross-reactive neutralizing antibodies against PRRSV in the sow population under field conditions

  2024cites this paper
• Gene expression of peripheral blood mononuclear cells and CD8+ T cells from gilts after PRRSV infection

  2023cites this paper
• Infection dynamics, transmission, and evolution after an outbreak of porcine reproductive and respiratory syndrome virus

  2023cites this paper
• Application of codon pair deoptimization for ORF7-induced attenuation of type I porcine reproductive and respiratory syndrome virus without reduced immune responses.

  2023cites this paper
• Occurrence and Associated Risk Factors of Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus Type 2 Infections in Greece

  2022cites this paper
• Investigation of Fas (APO-1)-Related Apoptosis in Piglets Intradermally or Intramuscularly Vaccinated with a Commercial PRRSV MLV

  2022cites this paper
• Evaluation of Four Commercial Vaccines for the Protection of Piglets against the Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus (hp-PRRSV) QH-08 Strain

  2021cites this paper
• Temporal lineage dynamics of the ORF5 gene of porcine reproductive and respiratory syndrome virus in Korea in 2014–2019

  2021cites this paper
• The Ability of Porcine Reproductive and Respiratory Syndrome Virus Isolates to Induce Broadly Reactive Neutralizing Antibodies Correlates With In Vivo Protection

  2021cites this paper
• Analysis of ORF5 sequences of Porcine Reproductive and Respiratory Syndrome virus (PRRSV) circulating within swine farms in Costa Rica

  2021cites this paper
• Porcine Reproductive and Respiratory Syndrome Virus

  2020cites this paper
• Broad Protection of Pigs against Heterologous PRRSV Strains by a GP5-Mosaic DNA Vaccine Prime/GP5-Mosaic rVaccinia (VACV) Vaccine Boost

  2020cites this paper
• Comparison of four commercial PRRSV MLV vaccines in herds with co-circulation of PRRSV-1 and PRRSV-2.

  2019cites this paper
• An Escherichia coli-Expressed Porcine Reproductive and Respiratory Syndrome Virus Chimeric Protein Induces a Specific Immunoglobulin G Response in Immunized Piglets

  2019cites this paper
• Evaluation of PRRSv specific, maternally derived and induced immune response in Ingelvac PRRSFLEX EU vaccinated piglets in the presence of maternally transferred immunity

  2019cites this paper
• First-Time Detection of Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus 2 in an Albanian Farrow-to-Finish Herd

  2018cites this paper
• Geographic distribution and molecular analysis of porcine reproductive and respiratory syndrome viruses circulating in swine farms in the Republic of Korea between 2013 and 2016

  2018cites this paper
• Efficacy and safety of simultaneous vaccination with two modified live virus vaccines against porcine reproductive and respiratory syndrome virus types 1 and 2 in pigs.

  2018cites this paper
• Recent advances in veterinary applications of structural vaccinology

  2018cites this paper
• Design of genetic construction for creation DNA vaccine against porcine reproductive and respiratory syndrome

  2018cites this paper
• Efficacy of a type 2 PRRSV modified live vaccine (PrimePac™ PRRS) against a Thai HP-PRRSV challenge

  2018cites this paper
• Effector mechanisms of humoral immunity to porcine reproductive and respiratory syndrome virus.

  2017cites this paper
• Polychlorinated dibenzo‐p‐dioxins and dibenzofurans levels in piglet liver with various diseases

  2017cites this paper
• Strategies to broaden the cross-protective efficacy of vaccines against porcine reproductive and respiratory syndrome virus.

  2017cites this paper
• Inactivated porcine reproductive and respiratory syndrome virus vaccine adjuvanted with Montanide™ Gel 01 ST elicits virus-specific cross-protective inter-genotypic response in piglets

  2016cites this paper
• Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena

  2016cites this paper
• Efficacy of Fostera PRRS modified live virus vaccine against a Canadian heterologous virulent field strain of porcine reproductive and respiratory syndrome virus.

  2016cites this paper
• Detection of porcine reproductive and respiratory syndrome virus (PRRSV) and influenza A virus (IAV) in oral fluid of pigs.

  2016cites this paper
• Virus replicon particles expressing porcine reproductive and respiratory syndrome virus proteins elicit immune priming but do not confer protection from viremia in pigs

  2016cites this paper
• Safety and efficacy of a novel European vaccine for porcine reproductive and respiratory virus in bred gilts.

  2016influential citation
• Vaccination of piglets at 2 and 3 weeks of age with Ingelvac PRRSFLEX® EU provides protection against heterologous field challenge in the face of homologous maternally derived antibodies

  2016influential citation
• Emergence of a virulent porcine reproductive and respiratory syndrome virus (PRRSV) 1 strain in Lower Austria

  2016cites this paper
• Safety and early onset of immunity with a novel European porcine reproductive and respiratory syndrome virus vaccine in young piglets.

  2016cites this paper
• Genetic diversity of the Korean field strains of porcine reproductive and respiratory syndrome virus.

  2016cites this paper
• Assessment of safety and reproductive performance after vaccination with a modified live-virus PRRS genotype 1 vaccine in pregnant sows at various stages of gestation.

  2016cites this paper
• Characterization of two novel porcine reproductive and respiratory syndrome virus isolates with deletions in the GP2 gene.

  2015cites this paper
• Efficacy of a combined inactivated porcine reproductive and respiratory syndrome virus vaccine using North American and European strains in specific pathogen free pigs.

  2015cites this paper
• A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection

  2015cites this paper
• Short report Open Access

  2015cites this paper
• Molecular epidemiology of porcine reproductive and respiratory syndrome viruses isolated from 1991 to 2013 in Taiwan

  2015cites this paper
• Immune Response of Multiparous Hyper-Immunized Sows against Peptides from Non-Structural and Structural Proteins of PRRSV

  2015cites this paper
• Cross-protection of a new type 2 porcine reproductive and respiratory syndrome virus (PRRSV) modified live vaccine (Fostera PRRS) against heterologous type 1 PRRSV challenge in growing pigs.

  2015cites this paper
• Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virus.

  2015cites this paper
• Inhibition of porcine reproductive and respiratory syndrome virus by Cecropin D in vitro.

  2015cites this paper
• Live porcine reproductive and respiratory syndrome virus vaccines: Current status and future direction.

  2015cites this paper
• Characterisation of the T cell response to the porcine reproductive and respiratory syndrome virus and its application towards the development of improved vaccines

  2015cites this paper
• Novel approaches towards vaccine developments against porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus

  2015cites this paper
• Transmission of porcine reproductive and respiratory syndrome virus (PRRSV): assessment of the reproduction rate (R) in different conditions

  2015cites this paper
• Porcine reproductive and respiratory syndrome (PRRS) in metapopulations : a mathematical model of persistence and control

  2014cites this paper
• Porcine reproductive and respiratory syndrome virus vaccines: current status and strategies to a universal vaccine.

  2014cites this paper
• Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity.

  2014cites this paper
• [The PRRSV-serumneutralization test detects gaps in herd immunity].

  2014cites this paper
• Evaluation of the efficacy of a new modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (Fostera PRRS) against heterologous PRRSV challenge.

  2014cites this paper
• Effects of zinc supplementation on virus infection in pigs

  2014cites this paper
• Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs

  2014cites this paper
• Reproductive, productivity, and mortality outcomes in late-gestation gilts and their litters following simulation of inadvertent exposure to a modified-live vaccine strain of porcine reproductive and respiratory syndrome (PRRS) virus.

  2014cites this paper
• Vaccination of sows against type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) before artificial insemination protects against type 2 PRRSV challenge but does not protect against type 1 PRRSV challenge in late gestation

  2014cites this paper
• Isotyping of porcine reproductive and respiratory syndrome (PRRS) virus antibody response and its diagnostic use

  2014cites this paper
• Medidas más relevantes para el control y la erradicación del PRRS

  2014cites this paper
• Prevention of heterologous Porcine Reproductive and Respiratory Syndrome Virus (PRRSv) infection using an antibody-virus complex vaccine

  2014cites this paper
• Preparation of North American Type II PRRSV Infectious Clone Expressing Green Fluorescent Protein

  2014cites this paper
• Efficacy of a Spanish modified live virus vaccine against homologous porcine reproductive and respiratory syndrome virus infection.

  2014cites this paper
• Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena.

  2014cites this paper
• Porcine reproductive and respiratory syndrome virus detection in Thailand during 2005–2010 in relation to clinical problems, pig types, regions, and seasons

  2013cites this paper
• Expression and Antibody Preparation of GP5a Gene of Porcine Reproductive and Respiratory Syndrome Virus

  2013cites this paper
• Comparison of different vaccination schedules for sustaining the immune response against porcine reproductive and respiratory syndrome virus.

  2013cites this paper
• Concurrent vaccinations against PCV2 and PRRSV: study on the specific immunity and clinical protection in naturally infected pigs.

  2013cites this paper
• Immunization with DNA Vaccines Containing Porcine Reproductive and Respiratory Syndrome Virus Open Reading Frames 5, 6, and 7 May Be Related to the Exacerbation of Clinical Disease after an Experimental Challenge

  2013cites this paper
• A study to assess the compatibility of simultaneous use of porcine reproductive and respiratory syndrome virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions.

  2013cites this paper
• Immune responses in mice vaccinated with virus-like particles composed of the GP5 and M proteins of porcine reproductive and respiratory syndrome virus

  2013cites this paper
• Genetic diversity of porcine reproductive and respiratory syndrome virus in Korea

  2013cites this paper
• Significance of genetic variation of PRRSV ORF5 in virus neutralization and molecular determinants corresponding to cross neutralization among PRRS viruses.

  2013cites this paper
• Porcine reproductive and respiratory syndrome virus: genetic diversity of recent British isolates.

  2013cites this paper
• Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines.

  2013cites this paper
• Risk factors for porcine reproductive and respiratory syndrome virus infection and resulting challenges for effective disease surveillance

  2012cites this paper
• Pig production in subtropical agriculture.

  2012cites this paper
• Cell-Mediated Immunity in Porcine Reproductive and Respiratory Syndrome Virus

  2012influential citation
• Épidémiologie du syndrome reproducteur et respiratoire porcin dans deux régions de densités porcines différentes au Québec

  2012cites this paper
• Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges

  2012cites this paper
• Impact of a killed PRRSV vaccine on sow longevity in a PRRSV infected swine herd

  2012cites this paper
• Tracing the genetic history of porcine reproductive and respiratory syndrome viruses derived from the complete ORF 5-7 sequences: a Bayesian coalescent approach

  2012cites this paper
• Microbial ecology of swine farms and PRRS vaccine vaccination strategies.

  2012cites this paper
• Novel insights in the physiological function of sialoadhesin as a downregulator of macrophage phagocytosis and its implications for viral infection

  2012cites this paper
• Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRSV vaccines.

  2012cites this paper
• Porcine Herd Health Management Practices for the Control of PRRSV Infection

  2012cites this paper
• Dissociation of porcine reproductive and respiratory syndrome virus neutralization from antibodies specific to major envelope protein surface epitopes.

  2012cites this paper
• Porcine reproductive and respiratory syndrome virus: antigenic and molecular diversity of British isolates and implications for diagnosis.

  2012cites this paper
• Porcine Respiratory and Reproductive Syndrome Virus Vaccinology: A Review for Commercial Vaccines

  2012cites this paper
• Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence

  2012cites this paper
• Emergence of novel European genotype porcine reproductive and respiratory syndrome virus in mainland China.

  2011cites this paper
• Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus.

  2011cites this paper
• Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS).

  2011cites this paper
• Genetic analysis of ORF5 in porcine reproductive and respiratory syndrome virus in Japan

  2011cites this paper
• Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus.

  2011cites this paper
• Characterization of a circulating PRRSV strain by means of random PCR cloning and full genome sequencing

  2011cites this paper
• Effect of compounds on the purification and antibody preparation of the extracellular domain fragment of the receptor CD163

  2011cites this paper
• Effect of the infection with porcine reproductive and respiratory syndrome virus on the regulation of cytokines - tumor necrosis factor-alpha and interleukin-10

  2011cites this paper