Signaling Cascades and Enzymes as Cryptococcus Virulence Factors

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/9781555816858.CH17
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Sec6‐dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans

  2009cited by this paper
• Vesicular transport across the fungal cell wall.

  2009cited by this paper
• Identification of ENA1 as a Virulence Gene of the Human Pathogenic Fungus Cryptococcus neoformans through Signature-Tagged Insertional Mutagenesis

  2009cited by this paper
• Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report.

  2009cited by this paper
• Signalling pathways in the pathogenesis of Cryptococcus

  2009cited by this paper
• Fungal-derived immune modulating molecules.

  2009cited by this paper
• Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.

  2008cited by this paper
• Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans

  2008cited by this paper
• Saccharomyces cerevisiae Phospholipase C Regulates Transcription of Msn2p-Dependent Stress-Responsive Genes

  2008cited by this paper
• Role and mechanism of phosphatidylinositol‐specific phospholipase C in survival and virulence of Cryptococcus neoformans

  2008cited by this paper
• PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans.

  2008cited by this paper
• Calcineurin Inhibition or Mutation Enhances Cell Wall Inhibitors against Aspergillus fumigatus

  2007cited by this paper
• Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans.

  2007cited by this paper
• Cell Wall-linked Cryptococcal Phospholipase B1 Is a Source of Secreted Enzyme and a Determinant of Cell Wall Integrity*

  2007cited by this paper
• Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.

  2007cited by this paper
• Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence.

  2007cited by this paper
• Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence

  2007cited by this paper
• MAP kinase pathways as regulators of fungal virulence.

  2007cited by this paper
• Sensing the environment: lessons from fungi

  2007cited by this paper
• Immune response to Candida albicans is preserved despite defect in O-mannosylation of secretory proteins.

  2007cited by this paper
• Transcriptional Regulation by Protein Kinase A in Cryptococcus neoformans

  2007cited by this paper
• Eca1, a Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase, Is Involved in Stress Tolerance and Virulence in Cryptococcus neoformans

  2007cited by this paper
• Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections

  2007cited by this paper
• Calcineurin Regulation in Fungi and Beyond

  2007cited by this paper
• Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1

  2006cited by this paper
• Caspofungin Susceptibility in Aspergillus and Non-Aspergillus Molds: Inhibition of Glucan Synthase and Reduction of β-d-1,3 Glucan Levels in Culture

  2006cited by this paper
• Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport

  2006cited by this paper
• Cryptococcal Lipid Metabolism: Phospholipase B1 Is Implicated in Transcellular Metabolism of Macrophage-Derived Lipids

  2006cited by this paper
• Cell Wall Assembly in Saccharomyces cerevisiae

  2006cited by this paper
• N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring.

  2006cited by this paper
• Miltefosine--discovery of the antileishmanial activity of phospholipid derivatives.

  2006cited by this paper
• Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome.

  2006cited by this paper
• Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line.

  2006cited by this paper
• Cch1 Mediates Calcium Entry in Cryptococcus neoformans and Is Essential in Low-Calcium Environments

  2006cited by this paper
• Hexadecylphosphocholine (Miltefosine) Has Broad-Spectrum Fungicidal Activity and Is Efficacious in a Mouse Model of Cryptococcosis

  2006cited by this paper
• Lipid Rafts in Cryptococcus neoformans Concentrate the Virulence Determinants Phospholipase B1 and Cu/Zn Superoxide Dismutase

  2006cited by this paper
• The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins.

  2006cited by this paper
• Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts.

  2006cited by this paper
• A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis.

  2006cited by this paper
• Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence.

  2006cited by this paper
• Report Expulsion of Live Pathogenic Yeast by Macrophages

  2006cited by this paper
• Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade

  2005cited by this paper
• The Role and Mechanism of Diacylglycerol-Protein Kinase C1 Signaling in Melanogenesis by Cryptococcus neoformans*

  2005cited by this paper
• Calcineurin-Binding Protein Cbp1 Directs the Specificity of Calcineurin-Dependent Hyphal Elongation during Mating in Cryptococcus neoformans

  2005cited by this paper
• The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans

  2005cited by this paper
• Cryptococcus neoformans Resistance to Echinocandins: (1,3)β-Glucan Synthase Activity Is Sensitive to Echinocandins

  2005cited by this paper
• Attenuation of the Activity of Caspofungin at High Concentrations against Candida albicans: Possible Role of Cell Wall Integrity and Calcineurin Pathways

  2005cited by this paper
• Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

  2005cited by this paper
• Microstructure of cell wall-associated melanin in the human pathogenic fungus Cryptococcus neoformans.

  2005cited by this paper
• Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor.

  2005cited by this paper
• Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans

  2005cited by this paper
• Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans.

  2005cited by this paper
• Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA).

  2005cited by this paper
• Analysis of β-1,3-Glucan Assembly in Saccharomyces cerevisiae Using a Synthetic Interaction Network and Altered Sensitivity to Caspofungin

  2004cited by this paper
• In Vitro Interactions between Antifungals and Immunosuppressants against Aspergillus fumigatus

  2004cited by this paper
• The cell wall sensor Wsc1p is involved in reorganization of actin cytoskeleton in response to hypo‐osmotic shock in Saccharomyces cerevisiae

  2004cited by this paper
• Caspofungin Uptake Is Mediated by a High-Affinity Transporter in Candida albicans

  2004cited by this paper
• Paradoxical Effect of Caspofungin: Reduced Activity against Candida albicans at High Drug Concentrations

  2004cited by this paper
• Genomic Approach to Identification of Mutations Affecting Caspofungin Susceptibility in Saccharomyces cerevisiae

  2004cited by this paper
• The Sphingolipid Pathway Regulates Pkc1 through the Formation of Diacylglycerol in Cryptococcus neoformans*

  2004cited by this paper
• Dual Mechanisms for Shedding of the Cellular Prion Protein*

  2004cited by this paper
• In Vitro Antifungal Activities of Inhibitors of Phospholipases from the Fungal Pathogen Cryptococcus neoformans

  2004cited by this paper
• Characterisation and expression of phospholipases B from the opportunistic fungus Aspergillus fumigatus.

  2004cited by this paper
• Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii.

  2004cited by this paper
• Incorporation of Sed1p into the cell wall of Saccharomyces cerevisiae involves KRE6.

  2004cited by this paper
• Role of Extracellular Phospholipases and Mononuclear Phagocytes in Dissemination of Cryptococcosis in a Murine Model

  2004cited by this paper
• Role of PLB1 in Pulmonary Inflammation and Cryptococcal Eicosanoid Production

  2003cited by this paper
• Identification of metabolites of importance in the pathogenesis of pulmonary cryptococcoma using nuclear magnetic resonance spectroscopy.

  2003cited by this paper
• The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function

  2003cited by this paper
• Cell wall α‐1,3‐glucan is required to anchor the Cryptococcus neoformans capsule

  2003cited by this paper
• Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans.

  2003cited by this paper
• Effects of Melanin upon Susceptibility of Cryptococcus to Antifungals

  2003cited by this paper
• Neurospora crassa FKS Protein Binds to the (1,3)β-Glucan Synthase Substrate, UDP-Glucose

  2003cited by this paper
• Phospholipid-Binding Protein Cts1 Controls Septation and Functions Coordinately with Calcineurin in Cryptococcus neoformans

  2003cited by this paper
• Isozymes delta of phosphoinositide-specific phospholipase C and their role in signal transduction in the cell.

  2003cited by this paper
• Dynamics of cell wall structure in Saccharomyces cerevisiae.

  2002cited by this paper
• Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)‐anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae

  2002cited by this paper
• Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase

  2002cited by this paper
• Good fungi gone bad: The corruption of calcineurin

  2002cited by this paper
• Phospholipase C is required for glucose‐induced calcium influx in budding yeast

  2002cited by this paper
• Actin patch assembly proteins Las17p and Sla1p restrict cell wall growth to daughter cells and interact with cis‐Golgi protein Kre6p

  2002cited by this paper
• Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wall

  2002cited by this paper
• GLUT4-containing vesicles are released from membranes by phospholipase D cleavage of a GPI anchor.

  2002cited by this paper
• Overexpression of Sbe2p, a Golgi Protein, Results in Resistance to Caspofungin in Saccharomyces cerevisiae

  2002cited by this paper
• Mutations in Fks1p affect the cell wall content of β‐1,3‐ and β‐1,6‐glucan in Saccharomyces cerevisiae

  2002cited by this paper
• Production of Prostaglandins and Leukotrienes by Pathogenic Fungi

  2002cited by this paper
• Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm

  2002cited by this paper
• Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae.

  2002cited by this paper
• Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

  2002cited by this paper
• Melanization of Cryptococcus neoformans and Histoplasma capsulatum Reduces Their Susceptibilities to Amphotericin B and Caspofungin

  2002cited by this paper
• An expanded view of inositol signaling.

  2001cited by this paper
• Arundifungin, a novel antifungal compound produced by fungi: biological activity and taxonomy of the producing organisms

  2001cited by this paper
• Caspofungin acetate: an antifungal agent.

  2001cited by this paper
• Molecular organization of the cell wall of Candida albicans.

  2001cited by this paper
• Regulation of phosphoinositide-specific phospholipase C.

  2001cited by this paper
• Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans

  2001cited by this paper
• Reintroduction of the PLB1 gene into Candida albicans restores virulence in vivo.

  2001cited by this paper
• Cryptococcomas distinguished from gliomas with MR spectroscopy: an experimental rat and cell culture study.

  2001cited by this paper
• Caspofungin: pharmacology, safety and therapeutic potential in superficial and invasive fungal infections

  2001cited by this paper
• Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans

  2001cited by this paper

• Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen

  2017cites this paper
• CHARACTERIZATION OF PUTATIVE ACETATE KINASE IN THE PATHOGENIC YEAST, CRYPTOCOCCUS NEOFORMANS

  2013cites this paper
• Cryptococcus–Neutrophil Interaction

  2012cites this paper
• Unravelling Secretion in Cryptococcus neoformans: More than One Way to Skin a Cat

  2011cites this paper
• Cryptococcus Neoformans Modulates Extracellular Killing by Neutrophils

  2011cites this paper