Neonatal screening for cystic fibrosis, using immunoreactive trypsin assay in dried blood spots.

No abstract is available for this paper.

• Publication year

  1981

• Venue

  Clinica chimica acta; international journal of clinical chemistry

• Publication date

  1981-06-18

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0009-8981(81)90145-5PMID 7249357
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Units for immunoreactive trypsin.

  1979cited by this paper
• Dried-blood spot screening for cystic fibrosis in the newborn.

  1979cited by this paper
• Determination of human pancreatic cationic trypsinogen in serum by radioimmunoassay.

  1979cited by this paper
• Sensitive trypsin assay for dried-blood specimens as a screening procedure for early detection of cystic fibrosis.

  1979cited by this paper
• Classification at time of diagnosis and subsequent survival in children with cystic fibrosis.

  1977cited by this paper
• The effect of early diagnosis and treatment in cystic fibrosis: a seven-year study of 16 sibling pairs.

  1977cited by this paper
• Cystic-fibrosis screening in the newborn.

  1977cited by this paper
• Human pancreatic proteolytic enzymes and protein inhibitors. Isolation and molecular properties.

  1974cited by this paper
• Human Pancreatic Proteolytic Enzymes and Protein Inhibitors

  1974cited by this paper

• An Explorative Qualitative Study of the Role of a Genetic Counsellor to Parents Receiving a Diagnosis After a Positive Newborn Bloodspot Screening

  2025cites this paper
• Serum trypsin is a reliable biomarker of pancreas function.

  2024cites this paper
• Fibrose cística: quando a triagem neonatal é insatisfatória para o diagnóstico precoce

  2024cites this paper
• Improved detection of cystic fibrosis by the California Newborn Screening Program for all races and ethnicities

  2024cites this paper
• IRT/IRT as a newborn cystic fibrosis screening method: optimal cutoff points for a mixed population

  2024cites this paper
• Newborn Screening Program for Cystic Fibrosis in Cuba: Three Years’ Experience

  2023cites this paper
• Update Mukoviszidose

  2022cites this paper
• The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models

  2022cites this paper
• Exocrine Pancreatic Insufficiency

  2021cites this paper
• Addressing Uncertainty: The Emergence of the CRMS/CFSPID Diagnostic Category Following Newborn Screening for Cystic Fibrosis

  2021cites this paper
• Cystic Fibrosis

  2021cites this paper
• Cystic Fibrosis—Diagnosis, Genetics and Lifelong Effects

  2021cites this paper
• Sweat chloride assay by inductively coupled plasma mass spectrometry: a confirmation test for cystic fibrosis diagnosis

  2020cites this paper
• The Evolution of Precision Medicine in Cystic Fibrosis

  2020cites this paper
• Cystic Fibrosis Diagnosis in Newborns, Children, and Adults

  2019cites this paper
• Equity in genetic newborn screening

  2019cites this paper
• Diagnosis and Presentation of Cystic Fibrosis

  2019cites this paper
• Diagnosis, Prognosis and Personalized Treatment of Cystic Fibrosis

  2018cites this paper
• Cystic fibrosis in the era of precision medicine.

  2017cites this paper
• Cystic Fibrosis Diagnosis and Newborn Screening.

  2016cites this paper
• A product of immunoreactive trypsinogen and pancreatitis-associated protein as second-tier strategy in cystic fibrosis newborn screening.

  2016cites this paper
• Improving the Sensitivity and Positive Predictive Value in a Cystic Fibrosis Newborn Screening Program Using a Repeat Immunoreactive Trypsinogen and Genetic Analysis.

  2016cites this paper
• Clinical approach to the diagnosis and treatment of cystic fibrosis and CFTR-related disorders

  2016cites this paper
• Implementation of newborn screening for cystic fibrosis in Norway. Results from the first three years.

  2016cites this paper
• Uncertain diagnosis after newborn screening for cystic fibrosis: An ethics‐based approach to a clinical dilemma

  2014cites this paper
• One-year evaluation of a neonatal screening program for cystic fibrosis in Switzerland.

  2013cites this paper
• Chapter 58 – Cystic Fibrosis

  2013cites this paper
• The retina in cystic fibrosis

  2013cites this paper
• Newborn screening for cystic fibrosis

  2012cites this paper
• Prevalência de baixa densidade mineral óssea e fatores associados em pacientes adolescentes e adultos com fibrose cística

  2012cites this paper
• Prospective and parallel assessments of cystic fibrosis newborn screening protocols in the Czech Republic: IRT/DNA/IRT versus IRT/PAP and IRT/PAP/DNA

  2012cites this paper
• Immunoreactive Trypsinogen (IRT) as a Biomarker for Cystic Fibrosis: challenges in newborn dried blood spot screening.

  2012cites this paper
• Retrospective analysis of stored dried blood spots from children with cystic fibrosis and matched controls to assess the performance of a proposed newborn screening protocol in Switzerland.

  2012cites this paper
• Biochemical and Molecular Genetic Testing Used in the Diagnosis and Assessment of Cystic Fibrosis

  2012influential citation
• Neugeborenenscreening auf Mukoviszidose

  2009cites this paper
• algorithmsfibrosis: terminology and diagnostic

  2008cites this paper
• Zinc and essential fatty acid status and supplementation in cystic fibrosis patients

  2008cites this paper
• Pancreatic phenotype in infants with cystic fibrosis identified by mutation screening

  2007cites this paper
• Biochemistry and Clinical Role of Trypsinogens and Pancreatic Secretory Trypsin Inhibitor

  2006cites this paper
• Klinika za pedijatriju Medicinskog fakulteta i KBC-a u Zagrebu,* Imunolo{ki zavod** i Zavod za za{titu zdravlja grada Zagreba*** ZNA^ENJE NOVORO\ENA^KOG PROBIRA NA CISTI^NU FIBROZU SIGNIFICANCE OF NEONATAL SCREENING FOR CYSTIC FIBROSIS

  2006cites this paper
• ZNAČENJE NOVOROĐENAČKOG PROBIRA NA CISTIČNU FIBROZU

  2006cites this paper
• Two-tiered immunoreactive trypsinogen-based newborn screening for cystic fibrosis in Colorado: screening efficacy and diagnostic outcomes.

  2005cites this paper
• Cystic fibrosis: terminology and diagnostic algorithms

  2005cites this paper
• Evidence on improved outcomes with early diagnosis of cystic fibrosis through neonatal screening: enough is enough!

  2005cites this paper
• Update on newborn screening for cystic fibrosis

  2004cites this paper
• Neonatale screening voor mucoviscidose

  2004cites this paper
• Conclusionsfroma Pilot ImmunoreactlveTrypainNewborn Screen for CystIcFibrosis

  2004cites this paper
• Newborn screening programmes for cystic fibrosis.

  2003cites this paper
• Newborn screening for cystic fibrosis: ensuring more good than harm.

  2003cites this paper
• Monoclonal Antibody against Human Trypsin: Production, Characterization, and Use for Diagnosis

  2002cites this paper
• Neonatal biochemical screening for disease.

  2002cites this paper
• Specific Monoclonal Antibody Against Human Trypsin

  2002cites this paper
• Negative sweat test in hypertrypsinaemic infants with cystic fibrosis carrying rare CFTR mutations

  2002cites this paper
• IRT-Bestimmung in Vollblutproben getrocknet auf Filterpapier als Suchtest auf Cystische Fibrose

  2001cites this paper
• Prevalence of CFTR mutations in hypertrypsinaemia detected through neonatal screening for cystic fibrosis

  2001cites this paper
• Apport de la biologie moléculaire au dépistage néonatal de la mucoviscidose

  2000cites this paper
• Neonatal screening for cystic fibrosis: present and future

  1999cites this paper
• Structure-Function Relationships

  1998influential citation
• Cystic fibrosis: molecular approaches to diagnosis.

  1998cites this paper
• Exocrine Disorders of the Pancreas

  1997cites this paper
• Pankreasinsuffizienz bei Mukoviszidose und metabolische Komplikationen — ein diagnostisch vielschichtiges Problem

  1996cites this paper
• Neonatal screening for cystic fibrosis using blood trypsin with complementary meconium lactase: an advisable strategy for the population of southern Europe

  1995cites this paper
• A specific immunoradiometric assay of cationic trypsin(ogen) that does not recognize trypsin-alpha-1-proteinase inhibitor complex.

  1995cites this paper
• The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis.

  1994cites this paper
• The Assessment of Gastrointestinal Function

  1994cites this paper
• Lipid levels in adults with cystic fibrosis.

  1994cites this paper
• Newborn screening for cystic fibrosis: Its evolution and a review of the current situation

  1993cites this paper
• Biochemical tests in the diagnosis of chronic pancreatitis and in the evaluation of pancreatic insufficiency.

  1993cites this paper
• The Neonatal Detection of Cystic Fibrosis by Measurement of Immunoreactive Trypsin in Blood

  1992cites this paper
• Screening for cystic fibrosis.

  1992cites this paper
• Assessment of pancreatic function in screened infants with cystic fibrosis

  1991cites this paper
• Advances in Human Genetics

  1991cites this paper
• Epidemiology of cystic fibrosis in latin america: Preliminary communication

  1991cites this paper
• Evaluation of Growth and Changes in Body Composition Following Neonatal Diagnosis of Cystic Fibrosis

  1991cites this paper
• Biochemical and molecular genetics of cystic fibrosis.

  1991cites this paper
• Newborn screening for cystic fibrosis: A historical perspective

  1991cites this paper
• Neonatal screening for cystic fibrosis in Wales and the West Midlands: clinical assessment after five years of screening.

  1991cites this paper
• Efficacy of statewide neonatal screening for cystic fibrosis by assay of trypsinogen concentrations.

  1991cites this paper
• Attitudes of parents of cystic fibrosis children towards neonatal screening and antenatal diagnosis

  1990cites this paper
• Attitudes of parents of cystic fibrosis children towards neonatal screening and antenatal diagnosis.

  1990cites this paper
• Pancreatic function in infants identified as having cystic fibrosis in a neonatal screening program.

  1990cites this paper
• Serum Mucin-Associated Antigen Levels of Cystic Fibrosis Patients Are Related to Their Ages and Clinical Statuses

  1989cites this paper
• Immunoreactive trypsinogen screening for cystic fibrosis: Characterization of infants with a false‐positive screening test

  1989cites this paper
• ELISA for human pancreatic elastase 1.

  1989cites this paper
• Neonatal screening for cystic fibrosis.

  1988cites this paper
• Screening for cystic fibrosis: a four year regional experience.

  1988cites this paper
• Screening for cystic fibrosis among newborns in Norway by measurement of serum/plasma trypsin-like immunoreactivity. Results of a 2 1/2-year pilot project.

  1988cites this paper
• Newborn screening for cystic fibrosis using an enzyme linked immunoabsorbent assay (ELISA) technique.

  1988cites this paper
• Cognitive development in transposition of the great vessels.

  1988cites this paper
• [Screening for hereditary diseases. What other screening?].

  1988cites this paper
• Monoclonal antibody-based enzyme immunoassay for trypsinogen in neonatal screening for cystic fibrosis.

  1987cites this paper
• Age-Related Alterations of Immunoreactive Pancreatic Cationic Trypsinogen in Sera from Cystic Fibrosis Patients with and without Pancreatic Insufficiency

  1986cites this paper
• Rat trypsin: purification, radioimmunoassay and age-related serum levels in normal and spontaneously diabetic BB Wistar rats.

  1985cites this paper
• Reduced morbidity in patients with cystic fibrosis detected by neonatal screening.

  1985cites this paper
• Advances in nonisotopic immunoassay.

  1985cites this paper
• Prenatal diagnosis of cystic fibrosis

  1985cites this paper
• SERUM LIPASE AND TRYPSIN IN NEONATAI DETECTION OF CYSTIC FIBROSIS

  1984cites this paper
• Immunoreactive pancreatic lipase test for neonatal detection of cystic fibrosis.

  1984cites this paper
• [Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases].

  1984cites this paper
• Mukoviszidose-Screening durch Bestimmung des immunreaktiven Trypsins

  1984cites this paper