Brain neuropeptides in central ventilatory and cardiovascular regulation in trout

Many neuropeptides and their G-protein coupled receptors (GPCRs) are present within the brain area involved in ventilatory and cardiovascular regulation but only a few mammalian studies have focused on the integrative physiological actions of neuropeptides on these vital cardio-respiratory regulations. Because both the central neuroanatomical substrates that govern motor ventilatory and cardiovascular output and the primary sequence of regulatory peptides and their receptors have been mostly conserved through evolution, we have developed a trout model to study the central action of native neuropeptides on cardio-ventilatory regulation. In the present review, we summarize the most recent results obtained using this non-mammalian model with a focus on PACAP, VIP, tachykinins, CRF, urotensin-1, CGRP, angiotensin-related peptides, urotensin-II, NPY, and PYY. We propose hypotheses regarding the physiological relevance of the results obtained.

• Publication year

  2012

• Venue

  Front. Endocrin.

• Publication date

  2012-09-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3389/fendo.2012.00124PMID 23115556PMCID 3483629
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of the true ortholog of the urotensin II-related peptide (URP) gene in teleosts.

  2012cited by this paper
• Central ventilatory and cardiovascular actions of calcitonin gene-related peptide in unanesthetized trout

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• Changes in plasma angiotensin subtypes in Japanese eel acclimated to various salinities from deionized water to double-strength seawater.

  2012cited by this paper
• Central ventilatory and cardiovascular actions of angiotensin peptides in trout.

  2012cited by this paper
• Central pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) decrease the baroreflex sensitivity in trout.

  2011influential reference
• Occurrence of two distinct urotensin II-related peptides in zebrafish provides new insight into the evolutionary history of the urotensin II gene family.

  2011cited by this paper
• Autonomic control of circulation in fish: a comparative view.

  2011cited by this paper
• Function and Pharmacology of Spinally-Projecting Sympathetic Pre-Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus

  2011cited by this paper
• Characterization of a native angiotensin from an anciently diverged serine protease inhibitor in lamprey.

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• Potent cardiovascular effects of homologous urotensin II (UII)-related peptide and UII in unanesthetized eels after peripheral and central injections.

  2011influential reference
• Time domains of the hypoxic ventilatory response in ectothermic vertebrates

  2011cited by this paper
• Control of respiration in fish, amphibians and reptiles.

  2010cited by this paper
• Involvement of non-NMDA receptors in central mediation of chemoreflexes in the shorthorn sculpin, Myoxocephalus scorpius.

  2010cited by this paper
• Predicted Functions of MdmX in Fine-Tuning the Response of p53 to DNA Damage

  2010cited by this paper
• Urotensin II, from fish to human

  2010influential reference
• Autonomic control of cardiorespiratory interactions in fish, amphibians and reptiles.

  2010cited by this paper
• Chapter 8 The Neuroendocrine Regulation of Fluid Intake and Fluid Balance

  2009cited by this paper
• Central hyperventilatory action of the stress-related neurohormonal peptides, corticotropin-releasing factor and urotensin-I in the trout Oncorhynchus mykiss.

  2009influential reference
• Central control of cardiorespiratory interactions in fish.

  2009cited by this paper
• Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

  2009cited by this paper
• Central Effects of Trout Tachykinins on Heart Rate Variability in Trout

  2009cited by this paper
• Differential regulation of the central neural cardiorespiratory system by metabotropic neurotransmitters

  2009cited by this paper
• Effect of calcitonin gene-related peptide (CGRP), adrenomedullin and adrenomedullin-2/intermedin on food intake in goldfish (Carassius auratus).

  2009cited by this paper
• Ventilatory and cardiovascular actions of centrally and peripherally administered trout pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) in the unanaesthetized trout

  2009influential reference
• Comparative distribution of the mRNAs encoding urotensin I and urotensin II in zebrafish.

  2008cited by this paper
• Pituitary adenylate cyclase-activating polypeptide is vital for neonatal survival and the neuronal control of breathing

  2008cited by this paper
• Liberation of urotensin II from the teleost urophysis: an historical overview.

  2008cited by this paper
• Birth and death of neuropeptide Y receptor genes in relation to the teleost fish tetraploidization.

  2008cited by this paper
• Molecular characterization of calcitonin gene-related peptide (CGRP) related peptides (CGRP, amylin, adrenomedullin and adrenomedullin-2/intermedin) in goldfish (Carassius auratus): cloning and distribution.

  2008cited by this paper
• Hypothalamic mechanisms coordinating cardiorespiratory function during exercise and defensive behaviour.

  2008cited by this paper
• Variability in Cardiovascular Control: The Baroreflex Reconsidered

  2008cited by this paper
• Potent osmoregulatory actions of homologous adrenomedullins administered peripherally and centrally in eels.

  2008cited by this paper
• Renin‐angiotensin system revisited

  2008cited by this paper
• Neuromodulation and the orchestration of the respiratory rhythm.

  2008cited by this paper
• Distribution and Regional Stressor‐Induced Regulation of Corticotrophin‐Releasing Factor Binding Protein in Rainbow Trout (Oncorhynchus mykiss)

  2008cited by this paper
• Central and peripheral cardiovascular, ventilatory, and motor effects of trout urotensin-II in the trout.

  2008cited by this paper
• Central cardiovascular actions of angiotensin II in trout.

  2008cited by this paper
• Class II G protein-coupled receptors for VIP and PACAP: structure, models of activation and pharmacology.

  2007cited by this paper
• Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions.

  2007influential reference
• Ventilatory and cardiovascular actions of centrally administered trout tachykinins in the unanesthetized trout

  2007cited by this paper
• Central respiratory modulation of barosensitive neurones in rat caudal ventrolateral medulla

  2006cited by this paper
• Overview of the primary structure, tissue-distribution, and functions of tachykinins and their receptors.

  2006cited by this paper
• Molecular characterization and expression of urotensin II and its receptor in the flounder (Platichthys flesus): a hormone system supporting body fluid homeostasis in euryhaline fish.

  2006cited by this paper
• The corticotropin-releasing factor system as a mediator of the appetite-suppressing effects of stress in fish.

  2006cited by this paper
• Effects of Pituitary Adenylate Cyclase‐Activating Polypeptide and Vasoactive Intestinal Polypeptide on Food Intake and Locomotor Activity in the Goldfish, Carassius auratus

  2006cited by this paper
• Cardiovascular actions of the stress-related neurohormonal peptides, corticotropin-releasing factor and urotensin-I in the trout Oncorhynchus mykiss.

  2006cited by this paper
• Central effects of calcitonin receptor-stimulating peptide-1 on energy homeostasis in rats.

  2006cited by this paper
• Branchial Chemoreceptor Regulation of Cardiorespiratory Function

  2006cited by this paper
• Physiology of local renin-angiotensin systems.

  2006cited by this paper
• Urotensin II and Urotensin II–Related Peptide

  2006cited by this paper
• Central actions of angiotensin II on spontaneous baroreflex sensitivity in the trout Onc orhynchus mykiss.

  2006cited by this paper
• Calcitonin Gene-Related Peptides

  2006cited by this paper
• Evolutionary history of the calcitonin gene-related peptide family in vertebrates revealed by comparative genomic analyses.

  2006cited by this paper
• LONG‐TERM REGULATION OF ARTERIAL BLOOD PRESSURE BY HYPOTHALAMIC NUCLEI: SOME CRITICAL QUESTIONS

  2005cited by this paper
• CRF-related peptides contribute to stress response and regulation of appetite in hypoxic rainbow trout.

  2005influential reference
• CRF and CRF receptors: role in stress responsivity and other behaviors.

  2004influential reference
• Functional organization of preoptic vasotocin and isotocin neurons in the brain of rainbow trout: central and neurohypophysial projections of single neurons.

  2004cited by this paper
• Central effects of native urotensin II on motor activity, ventilatory movements, and heart rate in the trout Oncorhynchus mykiss.

  2004cited by this paper
• Ancient evolution of stress-regulating peptides in vertebrates.

  2004cited by this paper
• Angiotensin II binding to tissues of the rainbow trout, Oncorhynchus mykiss, studied by autoradiography

  2004cited by this paper
• Identification of Angiotensin I in a Cyclostome, Lampetra fluviatilis

  2004cited by this paper
• Captopril blocks the cardiac actions of centrally administered angiotensin I in the trout Oncorhynchus mykiss.

  2004cited by this paper
• Intracerebroventricular administration of the angiotensin II receptor antagonist saralasin reduces respiratory rate and tidal volume variability in freely moving Wistar rats.

  2004cited by this paper
• The Tachykinin Peptide Family, with Particular Emphasis on Mammalian Tachykinins and Tachykinin Receptor Agonists

  2004influential reference
• N-methyl-D-aspartate receptors mediate chemoreflexes in the shorthorn sculpin Myoxocephalus scorpius

  2003cited by this paper
• Evidence for glutamatergic mechanisms in the vagal sensory pathway initiating cardiorespiratory reflexes in the shorthorn sculpin Myoxocephalus scorpius

  2003cited by this paper
• Central effects of various ligands on drinking behavior in eels acclimated to seawater

  2003cited by this paper
• Neuropeptide Y

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• Identification of central mechanisms vital for breathing in the channel catfish, Ictalurus punctatus.

  2003cited by this paper
• Central administration of corticotropin-releasing hormone stimulates locomotor activity in juvenile chinook salmon (Oncorhynchus tshawytscha).

  2002cited by this paper
• Branchial innervation.

  2002cited by this paper
• Heart rate variability, a target for the effects of angiotensin II in the brain of the trout Oncorhynchus mykiss.

  2002cited by this paper
• Paraventricular oxytocin neurons are involved in neural modulation of breathing.

  2002cited by this paper
• Calcitonin: characterisation and expression in a teleost fish, Fugu rubripes.

  2002influential reference
• Neuropeptide Y effects on vasorelaxation and intestinal contraction in the Atlantic cod Gadus morhua.

  2002cited by this paper
• Respiratory and metabolic effects of decreased osmolality in conscious rats.

  2001cited by this paper
• Relationship between pulse interval and respiratory sinus arrhythmia: a time- and frequency-domain analysis of the effects of atropine

  2001cited by this paper
• Evolution of vertebrate neuropeptides.

  2001cited by this paper
• Characterization of three corticotropin-releasing factor receptors in catfish: a novel third receptor is predominantly expressed in pituitary and urophysis.

  2001cited by this paper
• Cloning and functional pharmacology of two corticotropin-releasing factor receptors from a teleost fish.

  2001cited by this paper
• Angiotensin signaling and receptor types in teleost fish.

  2001cited by this paper
• Cardiovascular actions of CRH and urocortin: an update.

  2001cited by this paper
• Do existing measures of Poincare plot geometry reflect nonlinear features of heart rate variability?

  2001cited by this paper
• Fish as model in pharmacological and biological research.

  2001cited by this paper
• Angiotensin receptors--evolutionary overview and perspectives.

  2001cited by this paper
• Characterization of Three Corticotropin-Releasing Factor Receptors in Catfish: A Novel Third Receptor Is Predominantly Expressed in Pituitary and Urophysis*† * The nucleotide sequences reported in this paper have been submitted to the GenBank database with accession numbers cfCRF-R1, AF229359; cfCRF

  2001influential reference
• The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily.

  2000cited by this paper
• Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions.

  2000cited by this paper
• How to measure baroreflex sensitivity: from the cardiovascular laboratory to daily life

  2000cited by this paper
• Cloning of a calcitonin gene-related peptide receptor and a novel calcitonin receptor-like receptor from the gill of flounder, Paralichthys olivaceus.

  2000cited by this paper
• A role for corticotropin releasing factor and urocortin in behavioral responses to stressors.

  1999cited by this paper
• Differential expression of corticotropin-releasing factor (CRF) and urotensin I precursor genes, and evidence of CRF gene expression regulated by cortisol in goldfish brain.

  1999cited by this paper
• Cardiorespiratory responses to intracerebroventricular injection of neuropeptide Y in anaesthetised dogs.

  1999cited by this paper
• Differential expression of

  1999cited by this paper
• Modulation of respiratory frequency by peptidergic input to rhythmogenic neurons in the preBötzinger complex.

  1999cited by this paper
• Central control of the cardiovascular and respiratory systems and their interactions in vertebrates.

  1999influential reference
• Central adrenomedullin augments the baroreceptor reflex in conscious rabbits.

  1999cited by this paper
• Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates.

  1999cited by this paper
• Blood pressure regulation during hypotension in two teleost species: differential involvement of the renin-angiotensin and adrenergic systems

  1999cited by this paper

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  2018cites this paper
• Central and Peripheral Effects of Urotensin II and Urotensin II-Related Peptides on Cardiac Baroreflex Sensitivity in Trout

  2017cites this paper
• Effects of peripherally administered urotensin II and arginine vasotocin on the QT interval of the electrocardiogram in trout.

  2016cites this paper
• International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, Urotensin II–Related Peptide, and Their Receptor: From Structure to Function

  2015cites this paper
• Comparative Distribution and In Vitro Activities of the Urotensin II-Related Peptides URP1 and URP2 in Zebrafish: Evidence for Their Colocalization in Spinal Cerebrospinal Fluid-Contacting Neurons

  2015cites this paper
• Divergent cardio-ventilatory and locomotor effects of centrally and peripherally administered urotensin II and urotensin II-related peptides in trout

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  2015cites this paper
• Central ventilatory and cardiovascular actions of serotonin in trout.

  2014cites this paper
• Brainstem mechanisms controlling cardiovascular reflexes in channel catfish.

  2014cites this paper
• Effects of intracerebroventricular administered fluoxetine on cardio-ventilatory functions in rainbow trout (Oncorhynchus mykiss).

  2014cites this paper
• Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in heart of Atlantic salmon (Salmo salar L).

  2013cites this paper
• Neuropeptide Y – an early biomarker for cerebral vasospasm after aneurysmal subarachnoid hemorrhage

  2013cites this paper
• Central ventilatory and cardiovascular actions of trout gastrin-releasing peptide (GRP) in the unanesthetized trout

  2013influential citation