The zebrafish klf gene family.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Blood

• Publication date

  2001-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD.V98.6.1792PMID 11535513
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria.

  2000cited by this paper
• Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

  2000cited by this paper
• Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid beta-spectrin structure, and function in red cell morphogenesis and membrane stability.

  2000cited by this paper
• Gene expression pattern Expression of the KruÈppel-like zinc ® nger gene biklf during zebra ® sh development

  2000cited by this paper
• A comparative map of the zebrafish genome.

  2000cited by this paper
• FKLF-2: a novel Krüppel-like transcriptional factor that activates globin and other erythroid lineage genes.

  2000cited by this paper
• Effective targeted gene ‘knockdown’ in zebrafish

  2000cited by this paper
• Genes dependent on zebrafish cyclops function identified by AFLP differential gene expression screen

  2000cited by this paper
• Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription.

  2000cited by this paper
• Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction.

  2000cited by this paper
• Mammalian Krüppel-like transcription factors: more than just a pretty finger.

  1999cited by this paper
• Klf4 is a transcription factor required for establishing the barrier function of the skin

  1999cited by this paper
• Zebrafish genetic map with 2000 microsatellite markers.

  1999cited by this paper
• Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis.

  1999cited by this paper
• A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences.

  1999cited by this paper
• A new beta-globin gene from the zebrafish, betaE1, and its pattern of transcription during embryogenesis.

  1999cited by this paper
• Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis.

  1999cited by this paper
• FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes

  1999cited by this paper
• Bricks and mortar of the epidermal barrier

  1999cited by this paper
• Zebrafish hox clusters and vertebrate genome evolution.

  1998cited by this paper
• Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes.

  1998cited by this paper
• The development of the paired fins in the zebrafish (Danio rerio).

  1998cited by this paper
• Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia

  1998cited by this paper
• Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates.

  1998cited by this paper
• Human EZF, a Krüppel-like Zinc Finger Protein, Is Expressed in Vascular Endothelial Cells and Contains Transcriptional Activation and Repression Domains*

  1998cited by this paper
• Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases.

  1998cited by this paper
• Vertebrate genome evolution and the zebrafish gene map

  1998cited by this paper
• A zebrafish model for hepatoerythropoietic porphyria

  1998cited by this paper
• SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish.

  1998cited by this paper
• Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis.

  1998cited by this paper
• The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.

  1998cited by this paper
• Cloning the cDNA for a New Human Zinc Finger Protein Defines a Group of Closely Related Krüppel-like Transcription Factors*

  1998cited by this paper
• Regulation of Erythroid Krüppel-like Factor (EKLF) Transcriptional Activity by Phosphorylation of a Protein Kinase Casein Kinase II Site within Its Interaction Domain*

  1998cited by this paper
• Identification of the DNA sequence that interacts with the gut-enriched Krüppel-like factor.

  1998cited by this paper
• Vertebrate genome evolution and the zebrafish gene map

  1998cited by this paper
• Cloning and characterization of mCtBP2, a co‐repressor that associates with basic Krüppel‐like factor and other mammalian transcriptional regulators

  1998cited by this paper
• Understanding gene and allele function with two-hybrid methods.

  1997cited by this paper
• The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation.

  1997cited by this paper
• The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis.

  1997cited by this paper
• LKLF: A transcriptional regulator of single-positive T cell quiescence and survival.

  1997cited by this paper
• GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene.

  1997cited by this paper
• Two Potent Nuclear Localization Signals in the Gut-enriched Krüppel-like Factor Define a Subfamily of Closely Related Krüppel Proteins*

  1997cited by this paper
• The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.

  1997cited by this paper
• Expression of the gut‐enriched Krüppel‐like factor gene during development and intestinal tumorigenesis

  1997cited by this paper
• Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

  1996cited by this paper
• Characterization of zebrafish mutants with defects in embryonic hematopoiesis.

  1996cited by this paper
• Hematopoietic mutations in the zebrafish.

  1996cited by this paper
• Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells

  1996cited by this paper
• Erythroid Krüppel‐like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter‐ and intramolecular interactions.

  1996cited by this paper
• Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest*

  1996cited by this paper
• A Gene for a Novel Zinc-finger Protein Expressed in Differentiated Epithelial Cells and Transiently in Certain Mesenchymal Cells*

  1996cited by this paper
• Centromere-linkage analysis and consolidation of the zebrafish genetic map.

  1996cited by this paper
• Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

  1995cited by this paper
• Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

  1995cited by this paper
• Intraembryonic hematopoietic cell migration during vertebrate development.

  1995cited by this paper
• Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages.

  1995cited by this paper
• Half-tetrad analysis in zebrafish: mapping the ros mutation and the centromere of linkage group I.

  1995cited by this paper
• Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family

  1995cited by this paper
• The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a beta-globin promoter

  1995cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

  1993cited by this paper
• The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo.

  1992cited by this paper
• Recognition of DNA by Cys2,His2 zinc fingers

  1991cited by this paper
• Retinoic acid modifies development of the midbrain-hindbrain border and affects cranial ganglion formation in zebrafish embryos.

  1991cited by this paper
• Drosophila Krüppel protein is a transcriptional represser

  1990cited by this paper
• The Human Genome Contains Hundreds of Genes Coding for Finger Proteins of the Krüppel Type

  1989cited by this paper
• Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

  1989cited by this paper
• The GLI-Kruppel family of human genes

  1988cited by this paper
• A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene.

  1986cited by this paper
• ONTOGENESIS OF HAEMATOPOIETIC SITES IN BRACHYDANIO RERIO (HAMILTON‐BUCHANAN) (TELEOSTEI) *

  1977cited by this paper

• Comparative toxicological impacts of tire wear and latex particle leachates on zebrafish embryos: Chemical characterization, oxidative stress, and transcriptomic disruption.

  2025cites this paper
• Transcriptomic Analysis of the Rainbow Trout Response to Single and Co-Infections with Myxobolus cerebralis and Tetracapsuloides bryosalmonae at Sites of Parasite Entry

  2025influential citation
• KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7

  2025cites this paper
• Adaptation of Diqing Tibetan pigs to hypoxic and cold environments through extramedullary hematopoiesis and uncoupled thermogenesis in the liver

  2025cites this paper
• Avermectin disrupted hematopoietic development and lipid metabolism in zebrafish larvae.

  2025cites this paper
• Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis

  2024cites this paper
• Plxnd1-mediated mechanosensing of blood flow controls the caliber of the Dorsal Aorta via the transcription factor Klf2

  2024cites this paper
• Developmental regulation of primitive erythropoiesis

  2024cites this paper
• Cooperative contributions of the klf1 and klf17 genes in zebrafish primitive erythropoiesis

  2023cites this paper
• Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial-mesenchymal transition

  2022cites this paper
• MiR-144 Regulates Hemoglobin Expression in Human Erythroid Cell Line

  2020cites this paper
• Primary cilia mediate Klf2-dependant Notch activation in regenerating heart

  2020cites this paper
• Impact of short-term starvation and refeeding on the expression of KLF15 and regulatory mechanism of branched-chain amino acids metabolism in muscle of Chinese soft-shelled turtle (Pelodiscus sinensis).

  2020cites this paper
• MiR-125a-3p-KLF15-BCAA Regulates the Skeletal Muscle Branched-Chain Amino Acid Metabolism in Nile Tilapia (Oreochromis niloticus) During Starvation

  2020cites this paper
• Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

  2020cites this paper
• Optogenetic investigation of BMP target gene expression diversity

  2020cites this paper
• Transkriptionelle Regulation des microRNA Clusters 144-451 während der Hämatopoese sowie Leukämogenese

  2019influential citation
• RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio

  2019cites this paper
• The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation

  2019cites this paper
• Klf4 could be activated by Pou5f3/Stat3 to induce the expression of Nanog in Japanese flounder.

  2019cites this paper
• miR-141-3p affects apoptosis and migration of endometrial stromal cells by targeting KLF-12

  2019cites this paper
• The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

  2018cites this paper
• The zebrafish: A fintastic model for hematopoietic development and disease

  2018cites this paper
• Adriamycin inhibits embryonic development in zebrafish through downregulation of Kruppel‐like factor4

  2018cites this paper
• Gene expression profile during proliferation and differentiation of rainbow trout adipocyte precursor cells

  2017cites this paper
• Molecular identification and functional analysis of KLF2 in Plecoglossus altivelis (ayu): It's regulatory role in monocyte/macrophage activation

  2017cites this paper
• New insights into lipid and carbohydrate metabolism in teleost fish: transcriptional and functional characterization of adipocytes

  2016cites this paper
• Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis)

  2016cites this paper
• Generation of Transparent Zebrafish with Fluorescent Ovaries: A Living Visible Model for Reproductive Biology

  2016cites this paper
• SNP (rs1570360) in Transcriptional Factor Binding Sites of the VEGFA Promoter is Associated with Hypertensive Nephropathy and Diabetic Retinopathy

  2016cites this paper
• Zebrafish as a model for leukemia and other hematopoietic disorders

  2015cites this paper
• Fibroblast Growth Factor 21 Suppresses Adipogenesis in Pig Intramuscular Fat Cells

  2015cites this paper
• Kruppel‐like factor family genes are expressed during Xenopus embryogenesis and involved in germ layer formation and body axis patterning

  2015cites this paper
• Myocardium and BMP signaling are required for endocardial differentiation

  2015influential citation
• Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain.

  2015cites this paper
• Myocardium and BMP signaling are required for endocardial differentiation

  2015influential citation
• klf2a sh317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes

  2015influential citation
• Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation.

  2015cites this paper
• Krüppel-like factors, chromatin, and epigenetics: new frontiers in understanding the regulation of complex diseases

  2014cites this paper
• Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo

  2014cites this paper
• The role of the transcription factor KLF2 in vascular development and disease.

  2014cites this paper
• A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis.

  2014cites this paper
• Use of the Zebrafish Larvae as a Model to Study Cigarette Smoke Condensate Toxicity

  2014cites this paper
• Regulators of hemoglobin switching in zebrafish and human models

  2014cites this paper
• The role of the transcription factor klf2a in vascular biology

  2014cites this paper
• Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity.

  2013cites this paper
• Regulation of germ layer formation by pluripotency factors during embryogenesis

  2013cites this paper
• Krüppel-like factor 12 negatively regulates human endometrial stromal cell decidualization.

  2013cites this paper
• A New Family of Predicted Krüppel-Like Factor Genes and Pseudogenes in Placental Mammals

  2013influential citation
• Oxidative stress modulates KLF6Full and its splice variants.

  2012cites this paper
• Zebrafish embryos sequester and retain petrochemical combustion products: developmental and transcriptome consequences.

  2012cites this paper
• Zebrafish erythropoiesis and the utility of fish as models of anemia

  2012influential citation
• Zinc finger protein HZF1 promotes K562 cell proliferation by interacting with and inhibiting INCA1.

  2011cites this paper
• Zebrafish bloodthirsty: developmental expression and identification of the mammalian ortholog.

  2011cites this paper
• embryos stabilization of hematopoietic stem cell programming in zebrafish-NO signaling cascade is required for klf 2 a dependent −

  2011cites this paper
• A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos.

  2011cites this paper
• TIEG1-null tenocytes display age-dependent differences in their gene expression, adhesion, spreading and proliferation properties.

  2011cites this paper
• Fishing Pluripotency Mechanisms In Vivo

  2011cites this paper
• Regulation of KLFs on Globin Expression and Erythroid Differentiation

  2011cites this paper
• Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish.

  2011cites this paper
• Regulation of the human HBA genes by KLF4 in erythroid cell lines

  2010cites this paper
• Embryonic expression of the chicken krüppel‐like (KLF) transcription factor gene family

  2010cites this paper
• Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells.

  2010cites this paper
• Krüppel-like factor 2 cooperates with the ETS family protein ERG to activate Flk1 expression during vascular development

  2009cites this paper
• Prostate-specific Klf6 Inactivation Impairs Anterior Prostate Branching Morphogenesis through Increased Activation of the Shh Pathway*

  2009cites this paper
• The role of KLF6 and its splice variants in cancer therapy.

  2009cites this paper
• Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis.

  2009cites this paper
• Identification of novel genes involved in the development of the sword and gonopodium in swordtail fish

  2009cites this paper
• Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

  2009cites this paper
• Involvement of AP-2rep in morphogenesis of the axial mesoderm in Xenopus embryo

  2009influential citation
• Kruppel like factor 4 (KLF4): a transcription factor with diverse context-dependent functions

  2009cites this paper
• The Krüppel traffic report: Cooperative signals direct KLF8 nuclear transport

  2009cites this paper
• Krüppel-like Factors and the Liver

  2009cites this paper
• Krüppel-like factors in the vascular endothelium

  2009cites this paper
• during primitive erythropoiesis Mir-144 selectively regulates embryonic {alpha}-hemoglobin synthesis

  2009cites this paper
• Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation.

  2009influential citation
• Zebrafish in hematology: sushi or science?

  2008cites this paper
• Regulation of stem cells in the zebra fish hematopoietic system.

  2008cites this paper
• Zinc fingers in the pizza pie aorta.

  2008cites this paper
• Mir-144 selectively regulates embryonic -hemoglobin synthesis during primitive erythropoiesis

  2008influential citation
• Combinatorial regulation of novel erythroid gene expression in zebrafish.

  2008cites this paper
• A Krüppel-Like Factor in Caenorhabditis elegans with Essential Roles in Fat Regulation, Cell Death, and Phagocytosis

  2008cites this paper
• Cardiovascular proteomic analysis.

  2007cites this paper
• A global role for zebrafish klf4 in embryonic erythropoiesis.

  2007influential citation
• CONTROL DE L'EXPRESSIÓ DEL GEN GLUCOQUINASA EN FETGE D'SPARUS AURATA

  2007cites this paper
• Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

  2006cites this paper
• Identification, characterization, and expression pattern of the chicken EKLF gene

  2006influential citation
• Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6.

  2006cites this paper
• Transcriptional regulation of FKLF-2 (KLF13) gene in erythroid cells.

  2005cites this paper
• A novel C. elegans zinc finger transcription factor, lsy-2, required for the cell type-specific expression of the lsy-6 microRNA

  2005cites this paper
• Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos.

  2005cites this paper
• bloodthirsty, an RBCC/TRIM gene required for erythropoiesis in zebrafish.

  2005cites this paper
• 15-zinc finger protein Bloody Fingers is required for zebrafish morphogenetic movements during neurulation.

  2005cites this paper
• Transcription Factor KLF7 Is Important for Neuronal Morphogenesis in Selected Regions of the Nervous System

  2005cites this paper
• Zebrafish KLF4 is essential for anterior mesendoderm/pre‐polster differentiation and hatching

  2005cites this paper
• Regulation of Sp2 DNA-Binding Activity and trans-Activation

  2005cites this paper
• Mutant-specific gene programs in the zebrafish.

  2005cites this paper
• A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element.

  2005cites this paper
• Vascular implications of the Krüppel-like family of transcription factors.

  2005cites this paper
• Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.

  2005cites this paper