Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Annals of the Rheumatic Diseases

• Publication date

  2002-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1136/ard.61.8.704PMID 12117676PMCID PMC1754191
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Modulating the Th1/Th2 balance in inflammatory arthritis

  2004cited by this paper
• The inhibition of metalloproteinases as a therapeutic target in rheumatoid arthritis and osteoarthritis.

  2001cited by this paper
• Insulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1alpha.

  2001cited by this paper
• Modulation of the expression of matrix metalloproteinase and tissue inhibitors of metalloproteinases by TGF-beta1 and IGF-1 in primary human articular and bovine nasal chondrocytes stimulated with TNF-alpha.

  2001cited by this paper
• The combination of tumor necrosis factor alpha blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model.

  2001cited by this paper
• IL-1-Independent Role of IL-17 in Synovial Inflammation and Joint Destruction During Collagen-Induced Arthritis1

  2001cited by this paper
• TUMOR NECROSIS FACTOR-α BLOCKADE IN THE TREATMENT OF RHEUMATOID ARTHRITIS

  2001cited by this paper
• Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown.

  2001cited by this paper
• Cytokine expression and synovial pathology in the initiation and spontaneous resolution phases of adjuvant arthritis: Interleukin‐17 expression is upregulated in early disease

  2001cited by this paper
• IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

  2001cited by this paper
• Tumor necrosis factor-alpha blockade in the treatment of rheumatoid arthritis.

  2001cited by this paper
• Insulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1α

  2001cited by this paper
• Interleukin 13 blocks the release of collagen from bovine nasal cartilage treated with proinflammatory cytokines

  2001cited by this paper
• Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis.

  2000cited by this paper
• Reduction of interleukin-17-induced inhibition of chondrocyte proteoglycan synthesis in intact murine articular cartilage by interleukin-4.

  2000cited by this paper
• TRANSFORMING GROWTH FACTOR-β1 BLOCKS THE RELEASE OF COLLAGEN FRAGMENTS FROM BOVINE NASAL CARTILAGE STIMULATED BY ONCOSTATIN M IN COMBINATION WITH IL-1α

  2000cited by this paper
• High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism1

  2000cited by this paper
• Retinoic acid combines with interleukin‐1 to promote the degradation of collagen from bovine nasal cartilage: Matrix metalloproteinases‐1 and ‐13 are involved in cartilage collagen breakdown

  2000cited by this paper
• Transforming growth factor beta1 blocks the release of collagen fragments from boving nasal cartilage stimulated by oncostatin M in combination with IL-1alpha.

  2000cited by this paper
• Effect of interleukin 17 on proteoglycan degradation in murine knee joints

  2000cited by this paper
• Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium.

  1999cited by this paper
• Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways.

  1999cited by this paper
• 96-Well plate assays for measuring collagenase activity using (3)H-acetylated collagen.

  1999cited by this paper
• Oncostatin M production and regulation by human polymorphonuclear neutrophils.

  1999cited by this paper
• IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

  1998cited by this paper
• Preparation of recombinant tissue inhibitor of metalloproteinases-1 (TIMP-1) in high yield and identification of a hydrophobic surface feature.

  1998cited by this paper
• Comparative immunolocalization studies of collagenase 1 and collagenase 3 production in the rheumatoid lesion, and by human chondrocytes and synoviocytes in vitro.

  1998cited by this paper
• Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines.

  1998cited by this paper
• Interleukin-17-induced Gene Expression in Articular Chondrocytes Is Associated with Activation of Mitogen-activated Protein Kinases and NF-κB*

  1998cited by this paper
• IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

  1998cited by this paper
• The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint.

  1998cited by this paper
• The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis.

  1997cited by this paper
• Gp130 and the interleukin-6 family of cytokines.

  1997cited by this paper
• Biochemical Characterization of Human Collagenase-3 (*)

  1996cited by this paper
• Metalloproteinase inhibitors and the prevention of connective tissue breakdown.

  1996cited by this paper
• Interleukin‐6 and soluble interleukin‐6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast‐like cell formation

  1996cited by this paper
• Enrichment of differentiated CD45RBdim,CD27- memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis.

  1996cited by this paper
• Human IL-17: a novel cytokine derived from T cells.

  1995cited by this paper
• Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.

  1995cited by this paper
• In vivo studies of cartilage regeneration after damage induced by catabolin/interleukin-1.

  1991cited by this paper
• Synovial fluid concentration of five different cytokines in rheumatic diseases.

  1990cited by this paper
• Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

  1986cited by this paper
• The effect of serum on biosynthesis of proteoglycans by bovine articular cartilage in culture.

  1983cited by this paper
• The breakdown of collagen by chondrocytes

  1980cited by this paper
• Two Improved and Simplified Methods for the Spectrophotometric Determination of Hydroxyproline.

  1963cited by this paper

• Rethinking Bacterial Osteolysis: Translational Evidence From a Porcine Model and Fracture‐Related Infections

  2026cites this paper
• The Effect of IL-17A and Combined Mechanical Injury on Meniscal Tissue Integrity In Vitro

  2025cites this paper
• Evaluating the inhibition of IL-17A and TNFα in a cartilage explant model cultured with Th17-derived cytokines

  2024cites this paper
• Loss of collagen content is localized near cartilage lesions on the day of injurious loading and intensified on day 12

  2024cites this paper
• Therapeutic Potential of Hyaluronic acid hydrogel /Bone marrow stem cell-conditioned medium on Articulating Surfaces Associated with Induced Arthritis in Rabbit’s TMJ

  2024cites this paper
• The role of ixekizumab in the treatment of nonradiographic axial spondyloarthritis.

  2024cites this paper
• Single‐cell RNA‐seq in diabetic foot ulcer wound healing

  2024cites this paper
• Arthrofibrosis After Total Knee Arthroplasty: A Critical Analysis Review.

  2023cites this paper
• Network-based cytokine inference implicates Oncostatin M as a driver of knee osteoarthritis

  2023cites this paper
• The sodium does not affect joint pain and functional activity of knee osteoarthritis patients

  2023cites this paper
• Network-based cytokine inference implicates Oncostatin M as a driver for inflammation phenotype of knee osteoarthritis

  2023cites this paper
• Molecular Basic of Pharmacotherapy of Cytokine Imbalance as a Component of Intervertebral Disc Degeneration Treatment

  2023cites this paper
• Self-education Program for Osteoarthritis Reduces Sodium Intake, Knee Joint pain, and Serum Interleukin-17A level in Osteoarthritis Patients

  2022cites this paper
• Integrin Regulated Autoimmune Disorders: Understanding the Role of Mechanical Force in Autoimmunity

  2022cites this paper
• IL-17A and TNF synergistically drive expression of proinflammatory mediators in synovial fibroblasts via IκBζ-dependent induction of ELF3

  2022cites this paper
• Recent Update on Immunopathogenesis of Psoriasis

  2022cites this paper
• Bromelain Extract Exerts Antiarthritic Effects via Chondroprotection and the Suppression of TNF-α–Induced NF-κB and MAPK Signaling

  2021cites this paper
• Distinct roles of interleukin-17 and T helper 17 cells among autoimmune diseases

  2021cites this paper
• Exploring IL-17 in spondyloarthritis for development of novel treatments and biomarkers.

  2021cites this paper
• Research Online Research Online Pathological mechanisms and therapeutic outlooks for Pathological mechanisms and therapeutic outlooks for arthrofibrosis arthrofibrosis

  2020cites this paper
• Oxidative stress and immunological biomarkers in Ankylosing spondylitis patients

  2020cites this paper
• IL-17 regulates expression of cytokines in human osteoblasts rather than bone-specific genes

  2020influential citation
• Receptor Activator of Nuclear Factor kappa-B Ligand is Not Regulated During Chronic Osteomyelitis in Pigs.

  2020cites this paper
• CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

  2020cites this paper
• Anthocyanins and metabolites from purple rice inhibit IL-1β-induced matrix metalloproteinases expression in human articular chondrocytes through the NF-κB and ERK/MAPK pathway.

  2019cites this paper
• Proinflammatory Effects of IL-1β Combined with IL-17A Promoted Cartilage Degradation and Suppressed Genes Associated with Cartilage Matrix Synthesis In Vitro

  2019cites this paper
• Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study

  2019cites this paper
• Serum interleukin-23 level in rheumatoid arthritis patients: Relation to disease activity and severity

  2019cites this paper
• Recent advances in understanding the regulation of metalloproteinases

  2019cites this paper
• Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis

  2019cites this paper
• Association of rs763780 variation in interleukin 17F gene with the risk of knee osteoarthritis

  2019cites this paper
• Interleukin-17: Potential Target for Chronic Wounds

  2019cites this paper
• In vitro chondroprotective potential of Senna alata and Senna tora in porcine cartilage explants and their species differentiation by DNA barcoding-high resolution melting (Bar-HRM) analysis

  2019cites this paper
• Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

  2019cites this paper
• Detection and phenotypic characterization of drug (metabolite)-specific t-cells from patients with drug-induced skin and liver injury and healthy donors

  2019cites this paper
• Pathological mechanisms and therapeutic outlooks for arthrofibrosis

  2019cites this paper
• Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases

  2019cites this paper
• CUX1 and IκBζ mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

  2019cites this paper
• Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes

  2018cites this paper
• Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes

  2018cites this paper
• A review of ustekinumab in the treatment of psoriatic arthritis.

  2018cites this paper
• Roles of matrix metalloproteinases (MMPs) in SM-induced pathologies

  2018cites this paper
• Effect of bone marrow mesenchymal stem cells on healing of temporomandibular joints in rats with induced rheumatoid arthritis

  2018cites this paper
• Co-expression of CD21L and IL17A defines a subset of rheumatoid synovia, characterised by large lymphoid aggregates and high inflammation

  2018cites this paper
• Sensitivity of serum concentration of cartilage biomarkers to 21‐days of bed rest

  2018cites this paper
• Pro- and Anti-inflammatory Cytokine Profiles in Osteoarthritis

  2017cites this paper
• IL-22 expression is increased variedly in the initial phase, onset and chronic phase of a pristane-induced arthritis rat model

  2017cites this paper
• Rôle des MAPK dans la migration des lymphocytes Th17 à travers le collagène tridimensionnel (3D)

  2017cites this paper
• Exploiting the helminth-derived immunomodulator, ES-62 and its small molecule analogues to dissect the mechanisms underpinning the development of the pathogenic phenotype of synovial fibroblasts in autoimmune arthritis.

  2017cites this paper
• Interleukin-17 Can Induce Osteoarthritis in Rabbit Knee Joints Similar to Hulth's Method

  2017cites this paper
• Effects of β-d-mannuronic acid, as a novel non-steroidal anti-inflammatory medication within immunosuppressive properties, on IL17, RORγt, IL4 and GATA3 gene expressions in rheumatoid arthritis patients

  2017cites this paper
• Immunomodulatory Effect of Cytokines in the Differentiation of Mesenchymal Stem Cells: A Review.

  2017cites this paper
• MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease

  2017cites this paper
• Expression of IL-1β Receptor Antagonist in Patients with Severe Osteoarthritis of the Knee–The Mechanism Limiting the Inflammation in Osteoarthritis

  2017cites this paper
• Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype

  2017cites this paper
• Spotlight on ixekizumab for the treatment of moderate-to-severe plaque psoriasis: design, development, and use in therapy

  2017cites this paper
• Cytokine Pathways in Psoriasis and Psoriatic Arthritis

  2016cites this paper
• Rheumatoid arthritis onset in postmenopausal women: Does the ACPA seropositive subset result from genetic effects, estrogen deficiency, skewed profile of CD4(+) T-cells, and their interactions?

  2016cites this paper
• Comparable Immune Function Inhibition by the Infliximab Biosimilar CT-P13: Implications for Treatment of Inflammatory Bowel Disease

  2016cites this paper
• Secukinumab for rheumatology: development and its potential place in therapy

  2016cites this paper
• In the perspective of cartilage degradation in inflammatory joint diseases

  2016cites this paper
• The role of inflammatory factors in pathogenesis of postmenopausal osteoporosis

  2016cites this paper
• New insights into the role of T cells in pathogenesis of psoriasis and psoriatic arthritis

  2016cites this paper
• Low-Level Laser Therapy as an Alternative Treatment for Snake Envenomation

  2016cites this paper
• Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation*

  2016cites this paper
• Th-17 cells and serum IL-17 in rheumatoid arthritis patients: Correlation with disease activity and severity

  2016cites this paper
• IL-17 and Its Receptor System: a New Target for Psoriatic

  2015cites this paper
• Targeting the IL-23/IL-17 axis for the treatment of psoriasis and psoriatic arthritis

  2015cites this paper
• Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis.

  2015cites this paper
• Long-term ustekinumab therapy of psoriasis in patients with coexisting rheumatoid arthritis and Sjögren syndrome. Report of two cases and review of literature.

  2015cites this paper
• The genomic landscape of human immune-mediated diseases

  2015cites this paper
• Иммунопатогенети ческие мех а низмы действия устекинумаба - нового лекарственного средства для лечения псориатического артрита и псориаза

  2015cites this paper
• Role of IL-17 in the pathogenesis of psoriatic arthritis and axial spondyloarthritis

  2015cites this paper
• Stem cells in degenerative orthopaedic pathologies: effects of aging on therapeutic potential

  2015cites this paper
• Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases

  2015cites this paper
• Inhibition of G-Protein βγ Signaling Decreases Levels of Messenger RNAs Encoding Proinflammatory Cytokines in T Cell Receptor-Stimulated CD4+ T Helper Cells

  2015cites this paper
• IL-17 and Its Receptor System: a New Target for Psoriatic Arthritis

  2015cites this paper
• Kavanaugh, A. et al. (2014) Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT

  2014cites this paper
• The new era for the treatment of psoriasis and psoriatic arthritis: perspectives and validated strategies.

  2014cites this paper
• Polymorphism of interleukin-17 and its relation to mineral density of bones in perimenopausal women

  2014cites this paper
• Distinct Cytokine Profiles in Patients with Oligoarticular Juvenile Idiopathic Arthritis after in Vitro Blockade of T Cells by Cyclosporine and Abatacept

  2014cites this paper
• 20 – Tissue destruction and repair

  2014cites this paper
• IL-17 and IL-17R: an auspicious therapeutic target for psoriatic disease.

  2014cites this paper
• Effects of Interleukin-17A on Osteogenic Differentiation of Isolated Human Mesenchymal Stem Cells

  2014cites this paper
• Peran Alpha-S2 kasein Susu Kambing PE Terhadap Perbaikan Morfologi dan Histologi Membran Synovial Tikus Rheumatoid Arthritis

  2014cites this paper
• Association of IL-17A and IL-17F single nucleotide polymorphisms with susceptibility to osteoarthritis in a Korean population.

  2014cites this paper
• Effects and mechanisms of Geniposide on rats with adjuvant arthritis.

  2014cites this paper
• Influence of age on osteoarthritis progression after anterior cruciate ligament transection in rats.

  2014cites this paper
• Acquiring Chondrocyte Phenotype from Human Mesenchymal Stem Cells under Inflammatory Conditions

  2014cites this paper
• Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT-1 and PSUMMIT-2 trials

  2014cites this paper
• Rôle des neutrophiles inflammatoires exprimant RANK dans la résorption osseuse locale pathologique de la polyarthrite rhumatoïde : démonstration à partir du modèle murin d'arthrite K/BxN

  2014cites this paper
• The Role of Tumour Necrosis Factor in the Pathogenesis of Immune-Mediated Diseases

  2014cites this paper
• Diagnosing and treating psoriatic arthritis: an update

  2014cites this paper
• Role of IL-17 in Psoriasis and Psoriatic Arthritis

  2013cites this paper
• The Effects of CD20 inhibitors therapy in comparison to TNF α inhibitors therapy on IL-17 in patients with active Rheumatoid Arthritis .

  2013cites this paper
• Synergistic transcriptional regulation of collagenase gene expression in chondrocytes

  2013influential citation
• The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-κB in collagen-induced arthritis and bone marrow-derived macrophages.

  2013cites this paper
• α2β1 Integrin Regulates Th17 Cell Activity and Its Neutralization Decreases the Severity of Collagen-Induced Arthritis

  2013cites this paper
• Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells

  2013cites this paper
• Grape Seed Proanthocyanidin Extract Protects Against Carrageenan-Induced Lung Inflammation in Mice Through Reduction of Pro-inflammatory Markers and Chemokine Expressions

  2013cites this paper