Obtenção de extratos de própolis sob diferentes condições e avaliação de sua atividade antifúngica

Propolis is a resin collected by the bees Apis mellifera L., which contains several substances including the flavonoids. Due to a diversified chemical composition propolis presents some pharmacological actions, being distinguished the anti-inflammatory, healing, antitumoral and antimicrobial properties and, in particular, its antifungal action. This action has been tested against yeasts obtained from onychomycosis, which are infections of difficult and long treatment and they can manifest intolerable effects on the patient. The propolis appears as an efficient therapy option, as it has low toxicity and should be of dermal use. The aim of the present study was to evaluate the optimization of the propolis extractive process through physiochemical parameters and antifungal activity demonstration.

• Publication year

  2007

• Venue

  Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy

• Publication date

  2007-01-16

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1590/S0102-695X2007000300015
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• Antifungal activity was assessed for propolis extracts against yeasts obtained from onychomycosis.

  Confidence 0.96

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• Different propolis extractive conditions were evaluated using physicochemical parameters as part of process optimization.

  Confidence 0.97

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review

• antifungal activity

  biological activity

  The capacity of a propolis extract to inhibit fungal growth in the tested system.

  Aliases: antifungal action

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• onychomycosis

  condition

  A fungal infection of the nails that provides the clinical source of the yeast isolates discussed in the abstract.

  Aliases: nail fungal infection

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• physicochemical parameters

  measurement, parameter

  Physical and chemical measurements used to evaluate the extraction conditions and resulting extracts.

  Aliases: physiochemical parameters

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• propolis

  material

  A resin collected by Apis mellifera bees and investigated here as the source material for extract preparation.

  Aliases: bee propolis

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• propolis extract

  material, sample

  An extract prepared from propolis under the tested extraction conditions.

  Aliases: propolis extracts, extract of propolis

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• propolis extractive process optimization

  method

  The adjustment of propolis extraction conditions to improve or characterize the extraction process.

  Aliases: optimization of the propolis extractive process, extractive process optimization

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review
• yeasts from onychomycosis

  sample, organism

  Yeast isolates obtained from onychomycosis infections and used as the antifungal test organisms.

  Aliases: onychomycosis yeasts

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) reviewAK (4715169a40) review--------- ✂ Cut Here ✂ --------- (jqthcshryb) reviewmexicorea (qjvnbu8xg3) reviewAnonymous (12632b8b5f) review

• Reference method for broth dilution antifungal susceptibility testing of yeasts : Approved standard

  2008cited by this paper
• The frequency ofCandida species in onychomycosis

  2008cited by this paper
• Método para avaliação e pesquisa da atividade antimicrobiana de produtos de origem natural

  2007cited by this paper
• Antifungal activity of propolis extract against yeasts isolated from onychomycosis lesions.

  2006cited by this paper
• Estudo de toxicologia clínica de um fitoterápico a base de associações de plantas, mel e própolis

  2006cited by this paper
• Avaliação da segurança clínica de um fitoterápico contendo Mikania glomerata, Grindelia robusta, Copaifera officinalis, Myroxylon toluifera, Nasturtium officinale, própolis e mel em voluntários saudáveis

  2006cited by this paper
• The effect of bee propolis on oral pathogens and human gingival fibroblasts.

  2005cited by this paper
• Onychomycosis in Rome, Italy

  2004cited by this paper
• Application of an HPLC Method for Analysis of Propolis Extract

  2003cited by this paper
• Onicomicoses por fungos emergentes: anlise clnica, diagnstico laboratorial e reviso

  2003cited by this paper
• Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2‐year surveillance study

  2002cited by this paper
• Office practice-based confirmation of onychomycosis: a US nationwide prospective survey.

  2002cited by this paper
• Quality Control of Baccharis trimera (Less.) DC. (Asteraceae) Hydroalcoholic Extracts

  2000cited by this paper
• Avaliação farmacognóstica da própolis da região de Maringá

  2000cited by this paper
• OTIMIZAÇÃO DE PROCESSO EXTRATIVO DE PRÓPOLIS

  1999cited by this paper
• Antibacterial, antifungal and antiviral activity of propolis of different geographic origin.

  1999cited by this paper
• Review of the biological properties and toxicity of bee propolis (propolis).

  1998cited by this paper
• IN VITRO ACTIVITY OF PROPOLIS AGAINST BACTERIAL AND YEAST PATHOGENS ISOLATED FROM HUMAN INFECTIONS

  1995cited by this paper

• Effect of Brazilian green propolis extracts on the properties of Andean potato starch-chitosan blended films and their use in preserving Parmesan cheese.

  2025cites this paper
• Análise da Metodologia de Aceleração Cicatricial MAC® com uso da própolis e azul de toluidina na cicatrização de úlceras de membros inferiores.

  2024cites this paper
• Development and characterization of bacterial cellulose membrane incorporated with Witch hazel extract

  2023cites this paper
• Antioxidant and pharmacological activity of Cucumis melo var. cantaloupe

  2022cites this paper
• EFEITOS DO EXTRATO DE PRÓPOLIS SOBRE A QUALIDADE SANITÁRIA E FISIOLÓGICA DE SEMENTES DE ARROZ (Oryza sativa L.) E SOJA (Glycine max (l.) Merril)

  2021cites this paper
• Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark.

  2021cites this paper
• Antimicrobial Efficacy of Propolis-Containing Varnish in Children: A Randomized and Double-Blind Clinical Trial

  2021cites this paper
• Dose-response evaluation of propolis dental varnish in children: A randomized study.

  2020cites this paper
• TECHNOLOGICAL DEVELOPMENT OF OINTMENT BASED ON ETHANOLIC EXTRACT OF LIBIDIBIA FERREA FOR ANTIMICROBIAL ACTIVITY

  2020cites this paper
• Atividade antioxidante de extratos de própolis em vários solventes

  2020cites this paper
• Efeito larvicida da própolis em Aedes aegypti Linnaeus (Diptera: Culicidae).

  2019cites this paper
• Phenolic Composition and Antifungal Effect of Costus cf. arabicus L Against Yeast of the Candida Genus

  2019cites this paper
• A Arte de criar Abelhas

  2019cites this paper
• Evaluation of propolis extract as a disinfectant of Japanese quail (Coturnix coturnix japonica) hatching eggs

  2018cites this paper
• Propolis increases neutrophils response against Candida albicans through the increase of reactive oxygen species.

  2018cites this paper
• Seasonality on the antifungal potential of green propolis collected in Campo Grande - MS, Brazil

  2017cites this paper
• Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial

  2017cites this paper
• Antimicrobial activity and phytochemical characterization of Carya illinoensis 1 2

  2017cites this paper
• Antioxidant and antifungal activity of Romanian propolis

  2017cites this paper
• Nanostructured Propolis as Therapeutic Systems With Antimicrobial Activity

  2017cites this paper
• EXTRATO DE PRÓPOLIS NO CONTROLE DO Penicillium sp. E NA QUALIDADE DE SEMENTES DE COUVE-FLOR / EXTRACT OF PROPOLIS IN CONTROL OF Penicillium sp. AND IN THE QUALITY OF CAULIFLOWER SEEDS

  2017cites this paper
• Antimicrobial activity and phytochemical characterization of Carya illinoensis.

  2017cites this paper
• The Effects of In-Ovo Injection of Propolis on Egg Hatchability and Starter Live Performance of Japanese Quails

  2016cites this paper
• Aplicação de extrato de própolis na agricultura

  2016cites this paper
• Propolis as an alternative in prevention and control of dental cavity

  2016cites this paper
• Fungitoxicity activity of homeopathic medicines on Alternaria solani

  2016cites this paper
• Physicochemical properties and antioxidant capacity of propolis of stingless bees (Meliponinae) and Apisfrom two regions of Tocantins, Brazil

  2016cites this paper
• ANTIMICROBIAL ACTIVITY IRRIGATING SOLUTIONS TO PREPARE CHANNELS BIOMECHANICAL ROOT FACE TO Enterococcus faecalis

  2016cites this paper
• Resíduo da extração de própolis como inibidor bacteriano in vitro

  2016cites this paper
• Potential Indication of Propolis in Treatment of Oral Infection for Denture Wearers

  2015cites this paper
• AVALIAÇÃO DO POTENCIAL CARIOGÊNICO DE ANTI-HISTAMÍNICOS DE USO PEDIÁTRICO

  2015cites this paper
• Vaginal Yeasts and the Antifungal Action of Red Propolis Extract

  2015cites this paper
• USO DA PRÓPOLIS E ÓLEO DE NIM NO CONTROLE DOS FUNGOS Lasiodiplodia theobromae E Colletotrichum gloesporioides: PRINCIPAIS PATÓGENOS QUE ACOMETEM OS FRUTOS DA MANGA

  2015cites this paper
• ATIVIDADE ANTIBACTERIANA DE EXTRATO ETANÓLICO DE PRÓPOLIS PRODUZIDO POR ABELHAS Apis Mellifera FRENTE A Staphylococcus aureus E Salmonella bongori

  2015cites this paper
• Atividade biológica in vitro de própolis e óleos essenciais sobre o fungo Colletotrichum musae isolado de bananeira (Musa spp.)

  2015cites this paper
• EFEITO DE EXTRATOS DE Allamanda blanchetti NO CONTROLE DE Alternaria brassicicola EM MUDAS DE COUVE-MANTEIGA

  2015cites this paper
• VERIFICAÇÃO DA INTERFERÊNCIA DO SOLVENTE PROPILENOGLICOL SOBRE O EFEITO DA PRÓPOLIS NA PRODUÇÃO DE LAGARTAS DE Bombyx mori L. (LEPIDOPTERA: BOMBICIDAE) COMPARADO AO EXTRATO ALCOÓLICO DE PRÓPOLIS

  2015cites this paper
• Early State Research on Antifungal Natural Products

  2014cites this paper
• Avaliação da concentração e dos tipos de flavonoides na própolis, utilizando métodos quimiométricos de classificação e calibração

  2014cites this paper
• Aplicação de extrato etanólico de própolis no crescimento e produtividade do feijoeiro comum

  2014cites this paper
• 15576 - Indução de faseolina em feijão e na atividade antibacteriana sobre Xanthomonas axonopodis pv. phaseoli pelo extrato etanólico de própolis Phaseolin induction in bean and antibacterial activity against Xanthomonas axonopodis pv. phaseoli by propolis ethanol extract

  2014cites this paper
• UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO PROGRAMA DE PÓS-GRADUAÇÃO EM BIOCIÊNCIA ANIMAL

  2013cites this paper
• Erosive and cariogenicity potential of pediatric drugs: study of physicochemical parameters

  2013cites this paper
• Update on therapy for superficial mycoses: review article part I

  2013cites this paper
• Effects of prestorage application of propolis and storage time on eggshell microbial activity, hatchability, and chick performance in Japanese quail (Coturnix coturnix japonica) eggs.

  2013cites this paper
• Potencialidades fitoquímicas do melão (Cucumis melo L.) na região Noroeste do Rio Grande do Sul - Brasil

  2013cites this paper
• Potencialidades fitoquímicas do melão ( Cucumis melo L.) na região Noroeste do Rio Grande do Sul - Brasil.

  2013cites this paper
• Qualidade de ovos de codorna submetidos ou não a tratamento superficial da casca armazenados em diferentes ambientes Quality of quail eggs submitted or no to surface tr eatment of the shell stored in different environments

  2013cites this paper
• SUSTENTABILIDADE DA MELIPONICULTURA, ABELHA JANDAÍRA (Melipona subnitida DUCKE, 1910) E CONTROLE DE QUALIDADE DO MEL NO SEMIÁRIDO PARAIBANO.

  2013cites this paper
• Evaluation of Mucoadhesive Gels with Propolis (EPP-AF) in Preclinical Treatment of Candidiasis Vulvovaginal Infection

  2013cites this paper
• IDENTIFICAÇÃO DE FATORES ASSOCIADOS À OCORRÊNCIA DE DOENÇAS DE ABELHAS AFRICANIZADAS (Apis mellifera L.) EM APIÁRIOS DO ESTADO DO RIO DE JANEIRO

  2013cites this paper
• Qualidade de ovos de codorna submetidos ou não a tratamento superficial da casca armazenados em diferentes ambientes

  2013cites this paper
• Uso de biofilme de amido à base de própolis vermelha para a conservação de folhas de alface (Lactuca sativa)

  2013cites this paper
• MASTITE BOVINA POR Staphylococcus aureus: SENSIBILIDADE ÀS DROGAS ANTIMICROBIANAS E AO EXTRATO ALCOÓLICO DE PRÓPOLIS

  2012cites this paper
• Effects of propolis on eggshell microbial activity, hatchability, and chick performance in Japanese quail (Coturnix coturnix japonica) eggs.

  2012cites this paper
• Análise clínica e citológica do efeito do gel de própolis no tratamento da estomatite protética em pessoas idosas: Ensaio clínico randomizado controlado simples cego

  2012cites this paper
• The in vitro antifungal evaluation of a commercial extract of Chilean propolis against six fungi of agricultural importance

  2012cites this paper
• AÇÃO ANTIBACTERIANA DA PRÓPOLIS MARROM BRASILEIRA EM DIFERENTES SOLVENTES CONTRA Staphylococcus spp. ISOLADOS DE CASOS DE MASTITE CAPRINA

  2012cites this paper
• Caraterização química e biológica do própolis da “serra de Bornes” por TLC

  2012cites this paper
• Efeito da combinação de amiodarona com fluconazol, in vitro, frente a isolados de C. tropicalis resistentes ao fluconazol : novos olhares para antigos fármacos

  2012cites this paper
• Atividade antibacteriana de Brassica oleracea var. Capitata em modelos experimentais in vitro

  2012cites this paper
• PRÓPOLIS NO CONTROLE DA MASTITE BOVINA

  2012cites this paper
• Atividade antifúngica in vitro dos óleos essenciais de Coriandrum sativum L. (coentro) e Foeniculum vulgare Mill. (funcho) sobre cepas de Cryptococcus neoformans

  2012cites this paper
• A própolis no combate a tripanossomatídeos de importância médica: uma perspectiva terapêutica para doença de Chagas e Leishmaniose

  2011cites this paper
• Atividade Antimicrobiana de Produtos Naturais Frente a Bactérias Formadoras do Biofi lme Dentário Antimicrobial Activity of Herbal Products against Dental Biofi lm Forming Bacteria

  2011cites this paper
• Effect of the Thymus vulgaris essential oil on the growth of Streptococcus mutans

  2011cites this paper
• Caracterização e avaliação in vitro da atividade antibacteriana de vidro bioativo dopado com própolis verde de apis mellifera

  2011cites this paper
• PR Antibacterial Activity of Aqueous Extract of Appis mellifera Propolis from the City of Ibaiti , PR

  2011cites this paper
• Antimicrobial activity of propolis extract against Staphylococcus coagulase positive and Malassezia pachydermatis of canine otitis.

  2010cites this paper
• How do bees prevent hive infections? The antimicrobial properties of propolis

  2010cites this paper
• Development of a new propolis microemulsion system for topical applications

  2010cites this paper
• Avaliação clínica e laboratorial do gel da Uncaria tomentosa (Unha de Gato) sobre candidose oral

  2009cites this paper
• Therapeutic properties of propolis for treatment of skin lesions

  2009cites this paper
• Acción propóleos en el tratamiento de lesiones en la piel: estudio de la revisión de la literatura

  2009cites this paper
• Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts.

  2009cites this paper
• Brown propolis extract in feed as a growth promoter of Nile tilapia (Oreochromis niloticus, Linnaeus 1758) fingerlings.

  2009cites this paper
• STANDARDIZATION OF EXTRACTIVES OF GEOPROPOLIS OF Melipona f ascicula t a SMITH (TIUBA)

  2009cites this paper
• Variabilidade sazonal dos constituintes da própolis vermelha e bioatividade em Artermia salina

  2009cites this paper
• Ação terapêutica da própolis em lesões cutâneas

  2009cites this paper
• Ação de extratos aquoso e alcoólico de própolis sobre Malassezia spp isoladas do conduto auditivo de cães

  2008cites this paper
• Um marcador químico de fácil detecção para a própolis de Alecrim-do-Campo (Baccharis dracunculifolia)

  2008cites this paper
• Estudo in vitro e ex vivo da ação de diferentes concentrações de extratos de própolis frente aos microrganismos presentes na saliva de humanos

  2008cites this paper
• Própolis: atualizações sobre a química e a farmacologia

  2008cites this paper
• Avaliação farmacognóstica de geoprópolis de Melipona fasciculata Smith da Baixada maranhense, Brasil

  2008cites this paper
• Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities

  2008cites this paper
• Analysis of a Brazilian green propolis from Baccharis dracunculifolia by HPLC-APCI-MS and GC-MS

  2008cites this paper
• Analysis of the MAC ® healing acceleration methodology with the use of propolis and toluidine blue in the healing of lower limb ulcers

  year unknowncites this paper