Mutation Induction in Mice

No abstract is available for this paper.

• Publication year

  1974

• Venue

  Advances in radiation biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/B978-0-12-035404-7.50010-3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Ionizing radiation: Levels and effects.

  1974cited by this paper
• X-ray-induced specific-locus mutation rate in newborn male mice.

  1973cited by this paper
• Determination of the radiation-induced mutation rate for sex-linked lethals and detrimentals in the mouse.

  1972cited by this paper
• Mutagenic effects of repeated small radiation doses to mouse spermatogonia. I. Specific-locus mutation rates.

  1972cited by this paper
• Studies of irradiated mouse populations. IV. Effects on productivity in the 7th-18th generations.

  1972cited by this paper
• The relative frequency of induced mutations recovered from Drosophila melanogaster gametogenic stages irradiated at different dose rates

  1972cited by this paper
• Dose-rate and mutation frequency after irradiation of mouse spermatogonia.

  1972cited by this paper
• The RBE for high-LET radiations with respect to mutagenesis

  1972cited by this paper
• Incidence of Epidermal Lesions in Fish of the North-East Irish Sea Area, 1971

  1972cited by this paper
• Meiotic disjunction in mouse translocations and the determination of centromere position.

  1971cited by this paper
• Testing for recessive lethals in mice.

  1971cited by this paper
• The spermatogonial stem cell population in adult rats. I. Their morphology, proliferation and maturation

  1971cited by this paper
• Lifetime reproductive capacity in offspring of an irradiated mouse population.

  1971cited by this paper
• Mutation in eukaryotes.

  1971cited by this paper
• Studies on the induction of translocations in mouse spermatogonia. IV. Effects of acute gamma-irradiation.

  1971cited by this paper
• Symposium on mammalian radiation genetics, July 7–9th, 1970 summary and synthesis

  1971cited by this paper
• Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations.

  1971cited by this paper
• Estimates of the genetic risks from ionizing irradiation.

  1971cited by this paper
• Spermatogonial stem‐cell renewal in the mouse

  1971cited by this paper
• Comparative aspects of the effects of radiation during oogenesis.

  1971cited by this paper
• Natural mutation rates in the house mouse. Estimates for five specific loci and dominant mutations.

  1971cited by this paper
• Changes in sex proportion--an unacceptable way to estimate sex-linked recessive lethals.

  1971cited by this paper
• Radiation-induced translocations in spermatogonia of mice.

  1971cited by this paper
• A Search for Radiation-Induced Recessive Sex-Linked Lethal and Detrimental Mutations in Immature Germ Cells of the House Mouse (MUS MUSCULUS ).

  1971cited by this paper
• Producing and detecting paracentric chromosomal inversions in mice.

  1971cited by this paper
• Fitness of heterozygotes of deleterious recessive mutations in the mouse.

  1971cited by this paper
• A new concept of spermatogonial stem-cell renewal in the mouse and its relationship to genetic effects.

  1971cited by this paper
• Is there a Viral Component in the Genetic Background?

  1970cited by this paper
• Dose-response curve for the yield of translocations in mouse spermatogonia after repeated small radiation doses.

  1970cited by this paper
• Gamma ray-induced mutations in Drosophila melanogaster oocytes: the phenomenon of dose rate.

  1970cited by this paper
• Chemical mutagenesis in mammals and man.

  1970cited by this paper
• Induction of translocations in mouse spermatogonia by X-ray doses divided into many small fractions.

  1970cited by this paper
• Gene and chromosome mutation after large fractionated or unfractionated radiation doses to mouse spermatogonia.

  1969cited by this paper
• Dominant effects of recessive lethals in mice. II. Viability and mating ability.

  1969cited by this paper
• Differential transmission of translocations induced in spermatogonia of mice by irradiation.

  1969cited by this paper
• The genetic structure of natural populations of Drosophila melanogaster. 8. Natural selection on the degree of dominance of viability polygenes.

  1969cited by this paper
• The ineffectiveness of chronic irradiation with neutrons and gamma rays in inducing mutations in female mice.

  1969cited by this paper
• Genetics of natural populations. XL. Heterotic and deleterious effects of recessive lethals in populations of Drosophila pseudoobscura.

  1968cited by this paper
• EXPERIMENTAL POPULATION GENETICS

  1968cited by this paper
• The effects of acute single or fractionated x-ray treatment on mouse spermatogonia.

  1968cited by this paper
• The frequency of x-ray induced recessive visible mutations in the rat.

  1968cited by this paper
• Genetic Effects of Radiation on Mammalian Populations

  1968cited by this paper
• Re-examination of spermatogonial renewal in the rat by means of seminiferous tubules mounted "in toto".

  1968cited by this paper
• RECENT STUDIES ON THE GENETIC EFFECTS OF RADIATION IN MICE

  1968cited by this paper
• The effect of pre-fertilization maternal irradiation on prenatal, perinatal and postnatal survival in the albino rat.

  1968cited by this paper
• Unusual incorporation of tritiated thymidine into early diplotene oocytes of mice.

  1968cited by this paper
• The frequency of recessive lethals in an irradiated mouse population.

  1968cited by this paper
• Studies on the induction of translocations in mouse spermatogonia. I. The effect of dose-rate.

  1968cited by this paper
• The dominant effects of a recessive lethal in the mouse.

  1968cited by this paper
• Dominant radiation effects in mouse populations.

  1968cited by this paper
• Genetic repair phenomena and dose-rate effects in animals.

  1968cited by this paper
• Fine structure analysis of a chromosome segment in Drosophila melanogaster. Analysis of x-ray-induced lethals.

  1968cited by this paper
• Genetical Aspects of Radiosensitivity: Mechanisms of Repair

  1967cited by this paper
• THE REVERSED DOSE-RATE EFFECT WITH FAST NEUTRON IRRADIATION OF MOUSE SPERMATOGONIA.

  1967cited by this paper
• Spontaneous mutations and mutation rates in the house mouse.

  1967cited by this paper
• Dominant mutations affecting the skeleton in offspring of x-irradiated male mice.

  1966cited by this paper
• Mutation rates at a new set of specific loci in the mouse.

  1966cited by this paper
• A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia.

  1966cited by this paper
• Chemically induced mutations in mice.

  1966cited by this paper
• Do recessive lethals have dominant deleterious effects in mice?

  1966cited by this paper
• Biology of the laboratory mouse

  1966cited by this paper
• HERITABLE HISTOCOMPATIBILITY CHANGES: LYSOGENY IN MICE?

  1966cited by this paper
• Effects of ionizing radiation on the reproductive system

  1965cited by this paper
• THE FREQUENCY OF X-RAY INDUCED DOMINANT MUTATIONS AFFECTING THE SKELETON OF MICE.

  1965cited by this paper
• Visible mutation frequencies in Dahlbominus oogonia produced by acute x-rays and chronic gamma-radiation.

  1965cited by this paper
• Effect of the interval between irradiation and conception on mutation frequency in female mice.

  1965cited by this paper
• Maturation in vitro of Mouse, Sheep, Cow, Pig, Rhesus Monkey and Human Ovarian Oocytes

  1965cited by this paper
• CONGENITAL DEFECTS AS INDICATORS OF LIFELONG ABNORMAL PROCESSES.

  1965cited by this paper
• Genetic effects of supra-lethal x-ray treatment of male mice.

  1965cited by this paper
• Inherited histocompatibility changes in progeny of irradiated and unirradiated inbred mice.

  1965cited by this paper
• GENETIC EFFECTS OF CHRONIC IRRADIATION GIVEN TO MICE THROUGH THREE SUCCESSIVE GENERATIONS.

  1964cited by this paper
• DOMINANT EFFECTS ON PRODUCTIVITY IN OFFSPRING OF IRRADIATED MOUSE POPULATIONS.

  1964cited by this paper
• EFFECT OF IRRADIATION IN INFANCY ON THE MOUSE OVARY; A QUANTITATIVE STUDY OF OOCYTE SENSITIVITY.

  1964cited by this paper
• GENETIC EFFECTS OF SPERMATOGONIAL X-IRRADIATION ON PRODUCTIVITY OF F1 FEMALE MICE.

  1964cited by this paper
• PERSISTENCE OF POPULATIONS OF MICE EXPOSED TO SUBSTERILIZING DOSES OF SPERMATOGONIAL X-IRRADIATION.

  1964cited by this paper
• STUDIES OF IRRADIATED MOUSE POPULATIONS. 3. ACCUMULATION OF RECESSIVE LETHALS.

  1964cited by this paper
• THE EFFECT OF DOSE-RATE ON THE YIELD OF TRANSLOCATIONS AND DOMINANT LETHALS FOLLOWING SPERMATOGONIAL IRRADIATION OF MICE

  1964cited by this paper
• The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice

  1964cited by this paper
• EMBRYONIC MORTALITY IN MOUSE POPULATIONS AFTER ELEVEN GENERATIONS OF SPERMATOGONIAL IRRADIATION.

  1964cited by this paper
• EFFECTS OF LOW-LEVEL IRRADIATION ON FITNESS AND SKELETAL VARIATION IN AN INBRED MOUSE STRAIN.

  1964cited by this paper
• Report of the United Nations Scientific Committee on the Effects of Atomic Radiation

  1963cited by this paper
• Effect of irradiation in infancy on the fertility of female mice.

  1963cited by this paper
• Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

  1963cited by this paper
• ReviewReport of the United Nations Scientific Committee on the Effects of Atomic Radiation. General Assembly: Official Records: 17th Session. Supplement No. 16(A/5216), 1962.

  1963cited by this paper
• Genetic Effects of Chronic Low-dose Irradiation on Mice

  1963cited by this paper
• A SEARCH FOR HISTOCOMPATIBILITY DIFFERENCES BETWEEN IRRADIATED SUBLINES OF INBRED MICE

  1963cited by this paper
• Test for sex-linked lethals in irradiated mice.

  1962cited by this paper
• The rate of genetic divergence of sublines in the c57bl strain of mice.

  1962cited by this paper
• AUTORADIOGRAPHIC STUDY OF DNA SYNTHESIS AND THE CELL CYCLE IN SPERMATOGONIA AND SPERMATOCYTES OF MOUSE TESTIS USING TRITIATED THYMIDINE

  1962cited by this paper
• Gamma-Ray Sensitivity of Oocytes of Immature Mice

  1962cited by this paper
• Quantitative gnetics of skeletal variations in the mouse. II. Crosses between four inbred strains (C3H, DBA, C57BL, BALB/c).

  1962cited by this paper
• THE PERIOD OF DNA SYNTHESIS PRIOR TO MEIOSIS IN THE MOUSE

  1962cited by this paper
• Skeletal Abnormalities in the F(1) Generation of Mice Exposed to Ionizing Radiations.

  1962cited by this paper
• The ultrastructure of oogonia and oocytes in the foetal and neonatal rat

  1962cited by this paper
• A quantitative and cytological study of oogonia and oocytes in the foetal and neonatal rat

  1962cited by this paper
• Relation between x-ray sensivity and stages of the cell cycle in spermatogogonia of the mouse.

  1962cited by this paper
• An augmenting effect of dose fractionation on radiation-induced mutation rate in mice.

  1962cited by this paper
• Meiosis in Ovarian Oocytes of Adult Mammals

  1962cited by this paper
• Deoxyribonucleic Acid Synthesis in Oocytes of Mouse Embryos

  1962cited by this paper
• A comparison of mutation induced by acute X and chronic gamma irradiation in mice.

  1961cited by this paper

• Radiation‑induced impacts on female fertility and fecundity: perspectives from the viewpoint of radiation protection

  2026cites this paper
• Overview and future studies of potential hereditary effects of parental exposure to atomic bomb radiation on their offspring

  2025cites this paper
• The Central Role of Cytogenetics in Radiation Biology

  2024cites this paper
• Modelling DNA Damage-Repair and Beyond.

  2024cites this paper
• Modelling Cellular Response to Ionizing Radiation: Mechanistic, Semi-Mechanistic, and Phenomenological Approaches – a Historical Perspective

  2024cites this paper
• Muller and mutations: mouse study of George Snell (a postdoc of Muller) fails to confirm Muller’s fruit fly findings, and Muller fails to cite Snell’s findings

  2024cites this paper
• Insights into radiation carcinogenesis based on dose-rate effects in tissue stem cells

  2023influential citation
• Three major reasons why transgenerational effects of radiation are difficult to detect in humans

  2023influential citation
• Mutation studies including those targeting the T/t-complex—a century long project

  2022cites this paper
• Destabilizing Effects of Ionizing Radiation on Chromosomes: Sizing up the Damage

  2021cites this paper
• Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes

  2020cites this paper
• Field Study of the Possible Effect of Parental Irradiation on the Germline of Children Born to Cleanup Workers and Evacuees of the Chornobyl Accident.

  2020cites this paper
• The Selby-Russell Dispute Regarding the Nonreporting of Critical Data in the Mega-Mouse Experiments of Drs William and Liane Russell That Spanned Many Decades: What Happened, Current Status, and Some Ramifications

  2020cites this paper
• Verification of a dose rate-responsive dynamic equilibrium model on radiation-induced mutation frequencies in mice

  2019cites this paper
• History of radiation genetics: light and darkness

  2019cites this paper
• A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation

  2017cites this paper
• Radiation-Induced Deletions in Mouse Spermatogonia are Usually Large (over 200 kb) and Contain Little Sequence Similarity at the Junctions

  2017cites this paper
• Why Genetic Effects of Radiation are Observed in Mice but not in Humans

  2017cites this paper
• Genome-Wide Deletion Screening with the Array CGH Method in Mouse Offspring Derived from Irradiated Spermatogonia Indicates that Mutagenic Responses are Highly Variable among Genes

  2016cites this paper
• Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots

  2016cites this paper
• Mutation induction in the mouse and human germline

  2016cites this paper
• The effects of extremely low frequency magnetic fields on mutation induction in mice.

  2015cites this paper
• Dose and dose-rate effects of ionizing radiation: a discussion in the light of radiological protection

  2015influential citation
• Dose and dose-rate effects of ionizing radiation: a discussion in the light of radiological protection

  2015influential citation
• The genome-wide effects of ionizing radiation on mutation induction in the mammalian germline

  2015cites this paper
• Mutagenic Effects of Ionizing Radiation on Immature Rat Oocytes

  2014cites this paper
• 7.09 – Genetic Effects and Risk Estimation

  2014cites this paper
• The Transgenerational Effects of Parental Exposure to Mutagens in Mammals

  2013cites this paper
• Ionizing radiation and genetic risks. XVII. Formation mechanisms underlying naturally occurring DNA deletions in the human genome and their potential relevance for bridging the gap between induced DNA double-strand breaks and deletions in irradiated germ cells.

  2013cites this paper
• Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents.

  2013cites this paper
• Radiation effects on human heredity.

  2013cites this paper
• The Genetic Risk in Mice from Radiation: An Estimate of the Mutation Induction Rate per Genome

  2013cites this paper
• The effects of methyl-donor deficiency on mutation induction and transgenerational instability in mice.

  2012cites this paper
• The Effect of Dose Rate on the Frequency of Specific-Locus Mutations Induced in Mouse Spermatogonia is Restricted to Larger Lesions; a Retrospective Analysis of Historical Data

  2012cites this paper
• The Dose and Dose-Rate Effects of Paternal Irradiation on Transgenerational Instability in Mice: A Radiotherapy Connection

  2012cites this paper
• Genetic Susceptibility: Radiation Effects Relevant to Space Travel

  2012cites this paper
• The effects of maternal irradiation during adulthood on mutation induction and transgenerational instability in mice.

  2012cites this paper
• Genomic Instability in the Offspring of Irradiated Parents

  2012cites this paper
• Comparison of Data on Mutation Frequencies of Mice Caused by Radiation with Low Dose Model

  2012cites this paper
• Issues and Reviews in Teratology

  2012cites this paper
• Easy detection of GFP-positive mutants following forward mutations at specific gene locus in cultured human cells.

  2011cites this paper
• Roles of Stem Cells in Tissue Turnover and Radiation Carcinogenesis

  2010cites this paper
• The effects of in utero irradiation on mutation induction and transgenerational instability in mice.

  2009cites this paper
• Germline mutation induction at tandem repeat DNA loci January 2002

  2009cites this paper
• Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice

  2008cites this paper
• Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis.

  2008cites this paper
• The effects of Atm haploinsufficiency on mutation rate in the mouse germ line and somatic tissue.

  2008cites this paper
• Prevalence of Adult-Onset Multifactorial Disease among Offspring of Atomic Bomb Survivors

  2008cites this paper
• Segmental Copy‐Number Variation Observed in Japanese by Array‐CGH

  2008cites this paper
• Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice.

  2008cites this paper
• The effects of MSH2 deficiency on spontaneous and radiation-induced mutation rates in the mouse germline.

  2007cites this paper
• Estimation of Mutation Induction Rates in AT-Rich Sequences Using a Genome Scanning Approach after X Irradiation of Mouse Spermatogonia

  2007cites this paper
• Chromosome Aberrations do not Persist in the Lymphocytes or Bone Marrow Cells of Mice Irradiated In Utero or Soon after Birth

  2007cites this paper
• Mechanisms of mutation at mouse expanded simple tandem repeat (ESTR) loci

  2007cites this paper
• New approaches to assessing the effects of mutagenic agents on the integrity of the human genome.

  2007cites this paper
• The combined effects of xeroderma pigmentosum C deficiency and mutagens on mutation rates in the mouse germ line.

  2007cites this paper
• Maternal effects of the scid mutation on radiation-induced transgenerational instability in mice

  2007cites this paper
• Special Submission 70 YEARS OF RADIATION GENETICS: FRUIT FLIES, MICE AND HUMANS

  2006cites this paper
• Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays.

  2006cites this paper
• Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci.

  2006cites this paper
• Genomic instability in the offspring of irradiated parents: Facts and interpretations

  2006cites this paper
• Genetic effects of radiation in atomic-bomb survivors and their children: past, present and future.

  2006cites this paper
• Presented at an NIEHS Conference on DNA Repair and Mutagenesis in Eukaryotes, June 25-23, 1979, in Atlanta, Georgia Radiation- and Drug-Induced DNA Repair in Mammalian Oocytes and Embryos

  2005cites this paper
• Analysis of germline mutation rates in DNA-repair deficient mice.

  2005influential citation
• p53 deficiency does not affect mutation rate in the mouse germline

  2005cites this paper
• Radiation-Induced Mutation at Tandem Repeat DNA Loci in the Mouse Germline: Spectra and Doubling Doses

  2005cites this paper
• Discovery of numerous clusters of spontaneous mutations in the specific-locus test in mice necessitates major increases in estimates of doubling doses

  2004cites this paper
• Test systems for mutagenicity screening of environmental chemicals and their relevance for the evaluation of genetic hazards to man

  2004cites this paper
• A Genome Scanning Approach to Assess the Genetic Effects of Radiation in Mice and Humans

  2004influential citation
• No Evidence of Radiation Effect on Mutation Rates at Hypervariable Minisatellite Loci in the Germ Cells of Atomic Bomb Survivors

  2004cites this paper
• Germline mutation rates at tandem repeat loci in DNA-repair deficient mice.

  2004cites this paper
• Molecular biology methods in assessing radiation-induced hereditary risks in humans

  2004cites this paper
• Major impacts of gonadal mosaicism on hereditary risk estimation, origin of hereditary diseases, and evolution

  2004influential citation
• Effects of Ionising Radiation in the Low-Dose Range — Radiobiological Basis

  2004cites this paper
• Germline mutation induction at mouse repeat DNA loci by chemical mutagens.

  2003cites this paper
• Germline mutation induction at mouse and human tandem repeat DNA loci.

  2003influential citation
• Environmental biodosimetry: a biologically relevant tool for ecological risk assessment and biomonitoring.

  2003cites this paper
• Random ENU mutagenesis.

  2003cites this paper
• CHILDHOOD LEUKAEMIA AND RADIATION: THE SELLAFIELD JUDGMENT

  2002cites this paper
• Ionising radiation and mutation induction at mouse minisatellite loci. The story of the two generations.

  2002cites this paper
• Analysis of germline mutations induced by chemicals

  2002influential citation
• Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice

  2002cites this paper
• A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus.

  2002cites this paper
• Historical and Current Highlights in Radiation Biology: Has Anything Important Been Learned by Irradiating Cells?

  2002cites this paper
• Radiation-induced instability at mouse expanded simple tandem repeat (ESTR) loci.

  2002influential citation
• Candidate genes required for embryonic development: a comparative analysis of distal mouse chromosome 14 and human chromosome 13q22.

  2002cites this paper
• Chromosome Translocations in T. scripta: The Dose-Rate Effect and In Vivo Lymphocyte Radiation Response

  2001cites this paper
• ENU mutagenesis: analyzing gene function in mice.

  2001cites this paper
• Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates.

  2000cites this paper
• Ionizing radiation and genetic risks. XIII. Summary and synthesis of papers VI to XII and estimates of genetic risks in the year 2000.

  2000cites this paper
• Induction of minisatellite mutations in the mouse germline by low-dose chronic exposure to gamma-radiation and fission neutrons.

  2000cites this paper
• IARC MONOGRAPHS ON THE EVALUATION OF CARCINOGENIC RISKS TO HUMANS

  2000cites this paper
• No correlation between germline mutation at repeat DNA and meiotic crossover in male mice exposed to X-rays or cisplatin.

  2000cites this paper
• Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus

  2000cites this paper
• sources and effects of ionizing radiation

  2000cites this paper
• Changing perspectives on the genetic doubling dose of ionizing radiation for humans, mice, and Drosophila.

  1999cites this paper
• Life cycle of the mammalian germ cell: implication for spontaneous mutation frequencies.

  1999cites this paper
• Ionizing radiation and genetic risks. X. The potential "disease phenotypes" of radiation-induced genetic damage in humans: perspectives from human molecular biology and radiation genetics.

  1999cites this paper
• Significance of the perigametic interval as a major source of spontaneous mutations that result in mosaics

  1999cites this paper
• Differential response of mouse male germ-cell stages to radiation-induced specific-locus and dominant mutations.

  1998cites this paper