The staphylococcal alpha-toxin and leukotoxins

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/B978-0-12-800188-2.00025-2
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Internalization of staphylococcal leukotoxins that bind and divert the C5a receptor is required for intracellular Ca2+ mobilization by human neutrophils

  2015cited by this paper
• Basis of virulence in a Panton-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain.

  2015cited by this paper
• Nanopore sequencing: from imagination to reality.

  2015cited by this paper
• Panton-Valentine leukocidin osteomyelitis in children: a growing threat.

  2015cited by this paper
• Delta-toxin production deficiency in Staphylococcus aureus: a diagnostic marker of bone and joint infection chronicity linked with osteoblast invasion and biofilm formation.

  2015cited by this paper
• A droplet microfluidic system for sequential generation of lipid bilayers and transmembrane electrical recordings.

  2015cited by this paper
• Phenol-soluble modulins--critical determinants of staphylococcal virulence.

  2014cited by this paper
• Panton-Valentine Leukocidin (PVL)-Positive Health Care-Associated Methicillin-Resistant Staphylococcus aureus Isolates Are Associated with Skin and Soft Tissue Infections and Colonized Mainly by Infective PVL-Encoding Bacteriophages

  2014cited by this paper
• Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis.

  2014cited by this paper
• Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody

  2014cited by this paper
• Residues Essential for Panton-Valentine Leukocidin S Component Binding to Its Cell Receptor Suggest Both Plasticity and Adaptability in Its Interaction Surface

  2014cited by this paper
• α-Hemolysin, not Panton-Valentine leukocidin, impacts rabbit mortality from severe sepsis with methicillin-resistant Staphylococcus aureus osteomyelitis.

  2014cited by this paper
• Where does a Staphylococcus aureus vaccine stand?

  2014cited by this paper
• The Staphylococcal Toxins γ-Hemolysin AB and CB Differentially Target Phagocytes by Employing Specific Chemokine Receptors

  2014cited by this paper
• Levels of Alpha-Toxin Correlate with Distinct Phenotypic Response Profiles of Blood Mononuclear Cells and with agr Background of Community-Associated Staphylococcus aureus Isolates

  2014cited by this paper
• The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus

  2014cited by this paper
• Staphylococcus aureus mobile genetic elements

  2014cited by this paper
• Phenol-soluble modulins.

  2014cited by this paper
• Phenotypic and genotypic characterisation of Staphylococcus aureus causing musculoskeletal infections.

  2014cited by this paper
• Tissue-Specific Patterning of Host Innate Immune Responses by Staphylococcus aureus α-Toxin

  2014cited by this paper
• Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH*

  2014cited by this paper
• Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection.

  2014cited by this paper
• Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol‐soluble modulin α

  2014cited by this paper
• Kineret®/IL-1ra Blocks the IL-1/IL-8 Inflammatory Cascade during Recombinant Panton Valentine Leukocidin-Triggered Pneumonia but Not during S. aureus Infection

  2014cited by this paper
• Staphylococcus aureus Leukotoxin GH Promotes Formation of Neutrophil Extracellular Traps

  2013cited by this paper
• Activation of neutrophils by the two-component leukotoxin LukE/D from Staphylococcus aureus: proteomic analysis of the secretions.

  2013cited by this paper
• Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

  2013cited by this paper
• Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils

  2013cited by this paper
• Characterization of a Novel Panton-Valentine Leukocidin (PVL)-Encoding Staphylococcal Phage and Its Naturally PVL-Lacking Variant

  2013cited by this paper
• Variability of antibiotic susceptibility and toxin production of Staphylococcus aureus strains isolated from skin, soft tissue, and bone related infections

  2013cited by this paper
• Structural Insights into Clostridium perfringens Delta Toxin Pore Formation

  2013cited by this paper
• Staphylococcus aureus corneal infections: effect of the Panton-Valentine leukocidin (PVL) and antibody to PVL on virulence and pathology.

  2013cited by this paper
• Phenol-soluble modulins and staphylococcal infection

  2013cited by this paper
• The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors.

  2013cited by this paper
• γ-Hemolysin oligomeric structure and effect of its formation on supported lipid bilayers: an AFM investigation.

  2013cited by this paper
• Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

  2013cited by this paper
• Staphylococcal Protein A, Panton-Valentine Leukocidin and Coagulase Aggravate the Bone Loss and Bone Destruction in Osteomyelitis

  2013cited by this paper
• Staphylococcus aureus Phenol-Soluble Modulin Peptides Modulate Dendritic Cell Functions and Increase In Vitro Priming of Regulatory T Cells

  2013cited by this paper
• Environmental Microbiology: Control of Foodborne and Waterborne Diseases Course — January 6–11, 2014

  2013cited by this paper
• Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

  2013cited by this paper
• p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions.

  2013cited by this paper
• Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection.

  2013cited by this paper
• Staphylococcus aureus Causing Tropical Pyomyositis, Amazon Basin, Peru

  2013cited by this paper
• Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis.

  2012cited by this paper
• Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens*

  2012cited by this paper
• Host Response Signature to Staphylococcus aureus Alpha-Hemolysin Implicates Pulmonary Th17 Response

  2012cited by this paper
• Crystallization and preliminary crystallographic studies of both components of the staphylococcal LukE-LukD leukotoxin.

  2012cited by this paper
• Staphylococcal Panton-Valentine Leukocidin Induces Pro-Inflammatory Cytokine Production and Nuclear Factor-Kappa B Activation in Neutrophils

  2012cited by this paper
• CCR5 is a receptor for Staphylococcus aureus leukotoxin ED

  2012cited by this paper
• Distinct Roles of Phenol-Soluble Modulins in Spreading of Staphylococcus aureus on Wet Surfaces

  2012cited by this paper
• Staphylococcal leukotoxins trigger free intracellular Ca2+ rise in neurones, signalling through acidic stores and activation of store-operated channels

  2012cited by this paper
• Staphylococcus aureus Panton‐Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

  2012cited by this paper
• Cross‐talk between Staphylococcus aureus leukocidins‐intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome‐dependent manner

  2012cited by this paper
• Spontaneous tibiotalar arthrodesis as a complication of acute tibial osteomyelitis due to Panton-Valentine leukocidin-producing Staphylococcus aureus: a case report

  2012cited by this paper
• Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo

  2012cited by this paper
• Essential Staphylococcus aureus toxin export system

  2012cited by this paper
• How Staphylococcus aureus biofilms develop their characteristic structure

  2012cited by this paper
• Purified Staphylococcus aureus leukotoxin LukM/F' does not trigger inflammation in the bovine mammary gland.

  2011cited by this paper
• Panton-Valentine Leukocidin Does Play a Role in the Early Stage of Staphylococcus aureus Skin Infections: A Rabbit Model

  2011cited by this paper
• Coagulase-positive Staphylococcus pseudintermedius from animals causing human endocarditis.

  2011cited by this paper
• Genetic Requirement for ADAM10 in Severe Staphylococcus aureus Skin Infection

  2011cited by this paper
• Crystal structure of the octameric pore of staphylococcal γ-hemolysin reveals the β-barrel pore formation mechanism by two components

  2011cited by this paper
• Staphylococcal Panton-Valentine Leucocidin as a Major Virulence Factor Associated to Furuncles

  2011cited by this paper
• Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis

  2011cited by this paper
• A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection

  2011cited by this paper
• Genetic relatedness of methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolated from a dog and the dog owner.

  2011cited by this paper
• Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins

  2011cited by this paper
• Prompt and Successful Toxin-Targeting Treatment of Three Patients with Necrotizing Pneumonia Due to Staphylococcus aureus Strains Carrying the Panton-Valentine Leukocidin Genes

  2010cited by this paper
• Immunogenicity of toxins during Staphylococcus aureus infection.

  2010cited by this paper
• Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus α-hemolysin–mediated cellular injury

  2010cited by this paper
• Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils

  2010cited by this paper
• Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

  2010cited by this paper
• Binding of the Staphylococcus aureus leucotoxin LukM to its leucocyte targets.

  2010cited by this paper
• Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus.

  2010cited by this paper
• Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury

  2010cited by this paper
• Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

  2009cited by this paper
• The Influence of Membrane Lipids in Staphylococcus aureus Gamma-Hemolysins Pore Formation

  2008cited by this paper
• Analysis of the Specificity of Panton-Valentine Leucocidin and Gamma-Hemolysin F Component Binding

  2008cited by this paper
• RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.

  2008cited by this paper
• A covalent S‐F heterodimer of leucotoxin reveals molecular plasticity of β‐barrel pore‐forming toxins

  2008cited by this paper
• A molecular pin to study the dynamics of β-barrel formation in pore-forming toxins on erythrocytes: a sliding model

  2007cited by this paper
• Severe pyomyositis caused by Panton–Valentine leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst

  2007cited by this paper
• Distinction between Pore Assembly by Staphylococcal α-Toxin versus Leukotoxins

  2007cited by this paper
• Pathogenomic Sequence Analysis of Bacillus cereus and Bacillus thuringiensis Isolates Closely Related to Bacillus anthracis

  2006cited by this paper
• Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions.

  2006cited by this paper
• Homologous versus heterologous interactions in the bicomponent staphylococcal γ-haemolysin pore1

  2006cited by this paper
• Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils.

  2005cited by this paper
• Modification of lysine residues ofStaphylococcus aureus α-toxin: Effects on its channel-forming properties

  2005cited by this paper
• Staphylococcus aureus Bicomponent gamma-Hemolysins, HlgA, HlgB, and HlgC, Can Form Mixed Pores Containing All Components

  2005cited by this paper
• Ionic channels formed byStaphylococcus aureus alpha-toxin: Voltage-dependent inhibition by divalent and trivalent cations

  2005cited by this paper
• Community-Acquired Methicillin-Resistant Staphylococcus aureus Isolated in Switzerland Contains the Panton-Valentine Leukocidin or Exfoliative Toxin Genes

  2004cited by this paper
• Single DNA rotaxanes of a transmembrane pore protein.

  2004cited by this paper
• Crystal Structure of Leucotoxin S Component

  2004cited by this paper
• Caveolin-1 binding motif of α-hemolysin: its role in stability and pore formation

  2004cited by this paper
• The Identification and Structure of the Membrane-spanning Domain of the Clostridium septicum Alpha Toxin*

  2004cited by this paper
• Crystallization and preliminary crystallographic data of a leucotoxin S component from Staphylococcus aureus.

  2004cited by this paper
• Neutralization of Staphylococcus aureus Panton Valentine leukocidin by intravenous immunoglobulin in vitro.

  2004cited by this paper
• Nanopores: flossing with DNA.

  2004cited by this paper
• Polymer translocation through a nanopore. II. Excluded volume effect.

  2004cited by this paper
• Staphylococcus aureus alpha-toxin-induced pores: Channel-like behavior in lipid bilayers and patch clamped cells

  2004cited by this paper

• Overview of Bacterial Protein Toxins from Pathogenic Bacteria: Mode of Action and Insights into Evolution

  2024cites this paper
• MINIREVIEW Inhibiting bacterial toxins by channel blockage

  2016cites this paper
• Inhibiting bacterial toxins by channel blockage.

  2016cites this paper