Chapter 12. Antimicrobial Drugs – Clinical Problems and Opportunities

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Annual Reports in Medicinal Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0065-7743(08)61122-7
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of norfloxacin on DNA metabolism in Pseudomonas aeruginosa

  1986cited by this paper
• New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.

  1986cited by this paper
• Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus

  1986cited by this paper
• In-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents.

  1985cited by this paper
• Chapter 14. Determinants of Microbial Resistance to Beta-lactam Antibiotics

  1985cited by this paper
• Changing etiology of nosocomial bacteremia and fungemia and other hospital-acquired infections.

  1985cited by this paper
• Antimicrobial chemotherapy of septicemia due to methicillin-resistant Staphylococcus aureus

  1985cited by this paper
• Activity of ciprofloxacin against methicillin-resistant Staphylococcus aureus

  1985cited by this paper
• Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus

  1985cited by this paper
• In-vitro susceptibility of mycobacteria to ciprofloxacin.

  1985cited by this paper
• Chapter 13. β-Lactam Antibiotics

  1985cited by this paper
• Regulation of penicillin-binding protein activity: description of a methicillin-inducible penicillin-binding protein in Staphylococcus aureus

  1985cited by this paper
• Cefmetazole: a broad spectrum cephem antibiotic effective on methicillin- and cephem-resistant Staphylococcus aureus.

  1985cited by this paper
• Occurrence of a beta-lactam-inducible penicillin-binding protein in methicillin-resistant staphylococci

  1985cited by this paper
• Antibiotic tolerance among clinical isolates of bacteria.

  1985cited by this paper
• The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro

  1985cited by this paper
• Empiric amphotericin B therapy in patients with acute leukemia.

  1985cited by this paper
• Penicillin‐binding proteins of β‐lactam‐resistant strains of Staphylococcus aureus

  1985cited by this paper
• Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA.

  1985cited by this paper
• In vitro activity of Sch 34343 against enterococci and other gram-positive bacteria

  1985cited by this paper
• Multicenter study of the clinical efficacy of imipenem/cilastatin for treatment of serious infections.

  1985cited by this paper
• Basis and current scope of rational anti-inflammatory therapy.

  1985cited by this paper
• Mechanisms of microbial synergy in polymicrobial surgical infections.

  1985cited by this paper
• Role of beta-lactam hydrolysis in the mechanism of resistance of a beta-lactamase-constitutive Enterobacter cloacae strain to expanded-spectrum beta-lactams

  1985cited by this paper
• Liposomal amphotericin B for the treatment of systemic fungal infections in patients with cancer: a preliminary study.

  1985cited by this paper
• Fungemia in a cancer hospital: changing frequency, earlier onset, and results of therapy.

  1985cited by this paper
• Hospital charges for antibiotics.

  1985cited by this paper
• Current needs in chemotherapy for bacterial and fungal infections.

  1985cited by this paper
• Penicillin-binging proteins and the intrinsic resistance to βlactams in Gram-positive cocci

  1985cited by this paper
• Bacterial pathogens of increasing significance in hospital-acquired infections.

  1985cited by this paper
• Transition from resistance to hypersusceptibility to beta-lactam antibiotics associated with loss of a low-affinity penicillin-binding protein in a Streptococcus faecium mutant highly resistant to penicillin

  1985cited by this paper
• Chapter 14. Quinolone Antibacterial Agents

  1985cited by this paper
• The in-vitro activity of a novel penem FCE 22101 compared to other beta-lactam antibiotics.

  1985cited by this paper
• Comparison of the activities of coumermycin, ciprofloxacin, teicoplanin, and other non-beta-lactam antibiotics against clinical isolates of methicillin-resistant Staphylococcus aureus from various geographical locations

  1985cited by this paper
• Efficacy and safety of imipenem/cilastatin: a review of worldwide clinical experience.

  1985cited by this paper
• Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus

  1985cited by this paper
• Epidemiology of infections due to Pseudomonas aeruginosa.

  1984cited by this paper
• Staphylococcus aureus. The persistent pathogen (first of two parts).

  1984cited by this paper
• Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria

  1984cited by this paper
• Mode of action and in-vitro activity of vancomycin.

  1984cited by this paper
• Biochemical and physiologic basis for susceptibility and resistance of Pseudomonas aeruginosa to antimicrobial agents.

  1984cited by this paper
• The clinical challenge of infections due to Pseudomonas aeruginosa.

  1984cited by this paper
• Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes

  1984cited by this paper
• The virulence of Pseudomonas aeruginosa.

  1984cited by this paper
• The structure and mode of action of glycopeptide antibiotics of the vancomycin group.

  1984cited by this paper
• Vancomycin in infants and children: a review of pharmacology and indications for therapy and prophylaxis.

  1984cited by this paper
• Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus

  1984cited by this paper
• Clinical pharmacology of 99mTc-labeled liposomes in patients with cancer.

  1984cited by this paper
• Activity of cefsulodin and other agents against Pseudomonas aeruginosa.

  1984cited by this paper
• Transfer of the chromosomal bla gene from Enterobacter cloacae to Escherichia coli by RP4::mini-Mu

  1984cited by this paper
• Vancomycin use--an historical review.

  1984cited by this paper
• Prophylaxis of Candida albicans infection in neutropenic mice with liposome-encapsulated amphotericin B

  1984cited by this paper
• Chapter 13. Antifungal Chemotherapy

  1984cited by this paper
• Identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin

  1983cited by this paper
• Burn units as a source of methicillin-resistant Staphylococcus aureus infections.

  1983cited by this paper
• Occurrence and expression of imipemide (N-formimidoyl thienamycin) resistance in clinical isolates of coagulase-negative staphylococci

  1983cited by this paper
• Determination of minimum bactericidal concentrations of oxacillin for Staphylococcus aureus: influence and significance of technical factors

  1983cited by this paper
• Chapter 13. Bacterial Penicillin-Binding Proteins

  1983cited by this paper
• Resistance to Aminoglycosides: Mechanisms and Frequency

  1983cited by this paper
• Early results of a comparative trial of ceftazidime versus cephalothin, carbenicillin and gentamicin in the treatment of febrile granulocytopenic patients.

  1983cited by this paper
• Characterization of beta-lactamase induction in Enterobacter cloacae

  1983cited by this paper
• Thienamycin: development of imipenem-cilastatin

  1983cited by this paper
• Comparison of in vitro activity of FCE 22101, a new penem, with those of other beta-lactam antibiotics

  1983cited by this paper
• Ceftazidime therapy for serious infections.

  1983cited by this paper
• The emergence of bacterial resistance and its influence on empiric therapy.

  1983cited by this paper
• In-vitro and in-vivo antibacterial activity of imipenem against clinical isolates of bacteria.

  1983cited by this paper
• Spectrum of disease due to rapidly growing mycobacteria.

  1983cited by this paper
• Impact of methicillin-resistant Staphylococcus aureus on the incidence of nosocomial staphylococcal infections.

  1983cited by this paper
• Infection due to organisms of the Mycobacterium fortuitum complex after augmentation mammaplasty: clinical and epidemiologic features.

  1983cited by this paper
• Infections caused by Pseudomonas aeruginosa.

  1983cited by this paper
• Treatment and prophylaxis of disseminated infection due to Candida albicans in mice with liposome-encapsulated amphotericin B.

  1983cited by this paper
• In vitro activity of ciprofloxacin (Bay o 9867)

  1983cited by this paper
• The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations.

  1983cited by this paper
• Activity of imipenem on aerobic bacteria.

  1983cited by this paper
• Antimicrobial resistance in hospital organisms and its relation to antibiotic use.

  1983cited by this paper
• Streptococcus faecium ATCC 9790 penicillin-binding proteins and penicillin sensitivity are heavily influenced by growth conditions: proposal for an indirect mechanism of growth inhibition by beta-lactams

  1983cited by this paper
• Temperature-sensitive autolysis-defective mutants of Escherichia coli

  1983cited by this paper
• Imipenem versus moxalactam in the treatment of serious infections

  1983cited by this paper
• In vitro activity of N-formimidoyl thienamycin and other beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus

  1982cited by this paper
• Resistance to cefamandole: derepression of beta-lactamases by cefoxitin and mutation in Enterobacter cloacae.

  1982cited by this paper
• Mutational Enzymatic Resistance of Enterobacter Species to Beta-Lactam Antibiotics

  1982cited by this paper
• Coagulase-negative staphylococcal septicemia: experience in a newborn intensive care unit.

  1982cited by this paper
• In vitro synergistic activity of ethambutol, isoniazid, kanamycin, rifampin, and streptomycin against Mycobacterium avium-intracellulare complex

  1982cited by this paper
• Penicillin-binding proteins in a Staphylococcus aureus strain resistant to specific beta-lactam antibiotics

  1982cited by this paper
• Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia.

  1982cited by this paper
• Epidemiology of nosocomial infections caused by methicillin-resistant Staphylococcus aureus.

  1982cited by this paper
• The Future of β-Lactam Antibiotics

  1982cited by this paper
• Variables in demonstrating methicillin tolerance in Staphylococcus aureus strains

  1982cited by this paper
• Absence of β-Lactamase-Inducing Effect of Moxalactam

  1982cited by this paper
• Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa

  1982cited by this paper
• Methicillin-resistant Staphylococcus aureus: experience in a general hospital over four years.

  1982cited by this paper
• Resistance to cephalosporins among gentamicin-resistant klebsiellae.

  1982cited by this paper
• Disseminated Mycobacterium avium-intracellulare infection in homosexual men dying of acquired immunodeficiency.

  1982cited by this paper
• In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins

  1982cited by this paper
• pH-dependent penicillin tolerance of group B streptococci

  1981cited by this paper
• Monobactams—monocyclic β -lactam antibiotics produced by bacteria

  1981cited by this paper
• beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment

  1981cited by this paper
• Altered penicillin-binding proteins in methicillin-resistant strains of Staphylococcus aureus

  1981cited by this paper
• The in-vitro properties of ceftazidime.

  1981cited by this paper
• Decreased affinity of a penicillin-binding protein for β-lactam antibiotics in a clinical isolate of Staphylococcus aureus resistant to methicillin

  1981cited by this paper

• Detection of novel secondary metabolites.

  1991cites this paper
• Discovery and development of new antimicrobial agents

  1990cites this paper
• Chapter 15. Novel Approaches Toward Discovery of Antibacterial Agents

  1988cites this paper