Retinal waves and their role in visual system development

Developing retinal ganglion cells fire periodic bursts of action potentials that propagate across the retina, thus providing a source of highly patterned activity prior to the onset of vision. This activity – termed retinal waves – occurs during a period of development when neural circuits within the retina and retinal projections to the brain undergo extensive refinement. This chapter describes the details of the spatiotemporal correlations of retinal waves and reviews the evidence that addresses which aspects of visual system development rely on patterned activity.

• Publication year

  2013

• Venue

  Synapse Development and Maturation

• Publication date

  2013-08-29

• Fields of study

  Biology

• Identifiers
  DOI 10.1016/B978-0-12-397266-8.00153-8
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Light Prior to Eye Opening Promotes Retinal Waves and Eye-Specific Segregation.

  2018cited by this paper
• Refinement of Spatial Receptive Fields in the Developing Mouse Lateral Geniculate Nucleus Is Coordinated with Excitatory and Inhibitory Remodeling

  2018cited by this paper
• Tbr1 instructs laminar patterning of retinal ganglion cell dendrites

  2018cited by this paper
• Satb1 Regulates Contactin 5 to Pattern Dendrites of a Mammalian Retinal Ganglion Cell.

  2017cited by this paper
• Architecture, Function, and Assembly of the Mouse Visual System.

  2017cited by this paper
• Activity-dependent development of visual receptive fields.

  2017cited by this paper
• Uncorrelated Neural Firing in Mouse Visual Cortex during Spontaneous Retinal Waves

  2017cited by this paper
• Cellular and Molecular Analysis of Dendritic Morphogenesis in a Retinal Cell Type That Senses Color Contrast and Ventral Motion

  2017cited by this paper
• Rules for Shaping Neural Connections in the Developing Brain

  2017cited by this paper
• Retinal Wave Patterns Are Governed by Mutual Excitation among Starburst Amacrine Cells and Drive the Refinement and Maintenance of Visual Circuits

  2016cited by this paper
• Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

  2016cited by this paper
• An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus

  2016cited by this paper
• Glutamatergic Retinal Waves

  2016cited by this paper
• Neuron-glia signaling in developing retina mediated by neurotransmitter spillover

  2015cited by this paper
• CaV3.2 KO mice have altered retinal waves but normal direction selectivity

  2015cited by this paper
• Spatial pattern of spontaneous retinal waves instructs retinotopic map refinement more than activity frequency

  2015cited by this paper
• Optic flow instructs retinotopic map formation through a spatial to temporal to spatial transformation of visual information

  2014cited by this paper
• Spontaneous Network Activity and Synaptic Development

  2014cited by this paper
• Interplay of cell-autonomous and nonautonomous mechanisms tailors synaptic connectivity of converging axons in vivo.

  2014cited by this paper
• Competition of Bipolar Cell Dendrites and Axons in the Developing Retina

  2014cited by this paper
• Type II cadherins guide assembly of a direction-selective retinal circuit.

  2014cited by this paper
• Retinal input directs the recruitment of inhibitory interneurons into thalamic visual circuits.

  2014cited by this paper
• Visual circuit development requires patterned activity mediated by retinal acetylcholine receptors.

  2014cited by this paper
• Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse

  2013cited by this paper
• Diverse Visual Features Encoded in Mouse Lateral Geniculate Nucleus

  2013cited by this paper
• A role for correlated spontaneous activity in the assembly of neural circuits.

  2013cited by this paper
• Tuned Thalamic Excitation is Amplified by Visual Cortical Circuits

  2013cited by this paper
• Intersecting circuits generate precisely patterned retinal waves.

  2013cited by this paper
• Intrinsically photosensitive ganglion cells contribute to plasticity in retinal wave circuits

  2013cited by this paper
• Extrasynaptic glutamate and inhibitory neurotransmission modulate ganglion cell participation during glutamatergic retinal waves.

  2013cited by this paper
• Developmental mechanisms of topographic map formation and alignment.

  2013cited by this paper
• Retinal Input Regulates the Timing of Corticogeniculate Innervation

  2013cited by this paper
• A data repository and analysis framework for spontaneous neural activity recordings in developing retina

  2013cited by this paper
• Synapse maturation is enhanced in the binocular region of the retinocollicular map prior to eye opening.

  2012cited by this paper
• Retinal waves coordinate patterned activity throughout the developing visual system

  2012cited by this paper
• Peripheral and central inputs shape network dynamics in the developing visual cortex in vivo.

  2012cited by this paper
• Vision drives correlated activity without patterned spontaneous activity in developing Xenopus retina

  2012cited by this paper
• Spontaneous Activity Promotes Synapse Formation in a Cell-Type-Dependent Manner in the Developing Retina

  2012cited by this paper
• Cellular Mechanisms Underlying Spatiotemporal Features of Cholinergic Retinal Waves

  2012cited by this paper
• Eph and ephrin signaling in the formation of topographic maps.

  2012cited by this paper
• Supplemental Information Development of Cell Type-Specific Connectivity Patterns of Converging Excitatory Axons in the Retina

  2011cited by this paper
• Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit

  2011cited by this paper
• Development of asymmetric inhibition underlying direction selectivity in the retina

  2011cited by this paper
• Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

  2011cited by this paper
• Development of Single Retinofugal Axon Arbors in Normal and β2 Knock-Out Mice

  2011cited by this paper
• Control of neuronal morphology by the atypical cadherin Fat3.

  2011cited by this paper
• Visual Map Development Depends On The Temporal Pattern of Binocular Activity in Mice

  2011cited by this paper
• The Role of Neuronal Connexins 36 and 45 in Shaping Spontaneous Firing Patterns in the Developing Retina

  2011cited by this paper
• Laminar Restriction of Retinal Ganglion Cell Dendrites and Axons: Subtype-Specific Developmental Patterns Revealed with Transgenic Markers

  2010cited by this paper
• Transmembrane semaphorin signaling controls laminar stratification in the mammalian retina

  2010cited by this paper
• A novel null allele of mouse DSCAM survives to adulthood on an inbred C3H background with reduced phenotypic variability

  2010cited by this paper
• A conserved switch in sensory processing prepares developing neocortex for vision.

  2010cited by this paper
• Direction-Selective Ganglion Cells Show Symmetric Participation in Retinal Waves During Development

  2010cited by this paper
• “Slow Activity Transients” in Infant Rat Visual Cortex:A Spreading Synchronous Oscillation Patterned by Retinal Waves

  2010cited by this paper
• Mechanisms underlying spontaneous patterned activity in developing neural circuits

  2010cited by this paper
• Mouse Embryonic Retina Delivers Information Controlling Cortical Neurogenesis

  2010cited by this paper
• The immune protein CD3zeta is required for normal development of neural circuits in the retina.

  2010cited by this paper
• Visual map development: bidirectional signaling, bifunctional guidance molecules, and competition.

  2010cited by this paper
• Retinal waves are unlikely to instruct the formation of eye-specific retinogeniculate projections

  2009cited by this paper
• Neurotransmission selectively regulates synapse formation in parallel circuits in vivo

  2009cited by this paper
• Direction-Specific Disruption of Subcortical Visual Behavior and Receptive Fields in Mice Lacking the β2 Subunit of Nicotinic Acetylcholine Receptor

  2009cited by this paper
• Spatial-temporal patterns of retinal waves underlying activity-dependent refinement of retinofugal projections.

  2009cited by this paper
• Retinal waves are likely to instruct the formation of eye-specific retinogeniculate projections

  2009cited by this paper
• Making a visual map: mechanisms and molecules.

  2009cited by this paper
• A Multi-Component Model of the Developing Retinocollicular Pathway Incorporating Axonal and Synaptic Growth

  2009cited by this paper
• Switching Retinogeniculate Axon Laterality Leads to Normal Targeting but Abnormal Eye-Specific Segregation That Is Activity Dependent

  2009cited by this paper
• LTD and LTP at the developing retinogeniculate synapse.

  2009cited by this paper
• Burst-Time-Dependent Plasticity Robustly Guides ON/OFF Segregation in the Lateral Geniculate Nucleus

  2009cited by this paper
• Calcium-Dependent Increases in Protein Kinase-A Activity in Mouse Retinal Ganglion Cells Are Mediated by Multiple Adenylate Cyclases

  2009cited by this paper
• Retinal input instructs alignment of visual topographic maps.

  2009cited by this paper
• Synaptic and extrasynaptic factors governing glutamatergic retinal waves.

  2009cited by this paper
• Intrinsic patterning and experience-dependent mechanisms that generate eye-specific projections and binocular circuits in the visual pathway.

  2009cited by this paper
• On and off domains of geniculate afferents in cat primary visual cortex

  2008cited by this paper
• Roles of Ephrin-As and Structured Activity in the Development of Functional Maps in the Superior Colliculus

  2008cited by this paper
• Mechanisms of response homeostasis during retinocollicular map formation

  2008cited by this paper
• A precisely timed asynchronous pattern of ON and OFF retinal ganglion cell activity during propagation of retinal waves.

  2008cited by this paper
• Refinement of the retinogeniculate pathway

  2008cited by this paper
• Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

  2008cited by this paper
• Dscam and Sidekick proteins direct lamina-specific synaptic connections in vertebrate retina

  2008cited by this paper
• Retinal waves in mice lacking the β2 subunit of the nicotinic acetylcholine receptor

  2008cited by this paper
• Epibatidine application in vitro blocks retinal waves without silencing all retinal ganglion cell action potentials in developing retina of the mouse and ferret.

  2008cited by this paper
• Selective disruption of one Cartesian axis of cortical maps and receptive fields by deficiency in ephrin-As and structured activity.

  2008cited by this paper
• Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves

  2008cited by this paper
• Mechanisms underlying development of visual maps and receptive fields.

  2008cited by this paper
• Morphological properties of mouse retinal ganglion cells during postnatal development

  2007cited by this paper
• Vision and cortical map development.

  2007cited by this paper
• Critical periods in the visual system: changing views for a model of experience-dependent plasticity.

  2007cited by this paper
• Developmental Homeostasis of Mouse Retinocollicular Synapses

  2007cited by this paper
• A Burst-Based “Hebbian” Learning Rule at Retinogeniculate Synapses Links Retinal Waves to Activity-Dependent Refinement

  2007cited by this paper
• cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map

  2007cited by this paper
• Role of the calcium modulated cyclases in the development of the retinal projections

  2006cited by this paper
• Retinal Waves Trigger Spindle Bursts in the Neonatal Rat Visual Cortex

  2006cited by this paper
• Spontaneous retinal activity mediates development of ocular dominance columns and binocular receptive fields in v1.

  2006cited by this paper
• Failure to maintain eye-specific segregation in nob, a mutant with abnormally patterned retinal activity.

  2006cited by this paper
• A transient network of intrinsically bursting starburst cells underlies the generation of retinal waves

  2006cited by this paper
• In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells.

  2006cited by this paper
• Dynamics of Spontaneous Activity in the Fetal Macaque Retina during Development of Retinogeniculate Pathways

  2006cited by this paper
• Imaging of cAMP Levels and Protein Kinase A Activity Reveals That Retinal Waves Drive Oscillations in Second-Messenger Cascades

  2006cited by this paper
• Development of precise maps in visual cortex requires patterned spontaneous activity in the retina.

  2005cited by this paper
• Evidence for an Instructive Role of Retinal Activity in Retinotopic Map Refinement in the Superior Colliculus of the Mouse

  2005cited by this paper

• Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement.

  2026cites this paper
• OscNet: Machine Learning on CMOS Oscillator Networks

  2025cites this paper
• Molecular mechanism establishing the OFF pathway in vision

  2025cites this paper
• Predation without direction selectivity

  2024cites this paper
• Ocular Necessities: A Neuroethological Perspective on Vertebrate Visual Development

  2024cites this paper
• Unsupervised learning on spontaneous retinal activity leads to efficient neural representation geometry

  2023cites this paper
• Vision-dependent and -independent molecular maturation of mouse retinal ganglion cells

  2022cites this paper
• Cellular Mechanisms Underlying Embryonic Retinal Waves

  2022cites this paper