Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Molecular biology and evolution

• Publication date

  2015-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/molbev/msv195PMID 26358402
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Overexpression of an Outer Membrane Protein Associated with Decreased Susceptibility to Carbapenems in Proteus mirabilis

  2015cited by this paper
• Interplay of transcriptional and small RNA‐dependent control mechanisms regulates chitosugar uptake in Escherichia coli and Salmonella

  2014cited by this paper
• Selection of a Multidrug Resistance Plasmid by Sublethal Levels of Antibiotics and Heavy Metals

  2014cited by this paper
• The binding of antibiotics in OmpF porin.

  2013cited by this paper
• Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets.

  2013cited by this paper
• Conserved arginines on the rim of Hfq catalyze base pair formation and exchange

  2013cited by this paper
• Carbapenem and cefoxitin resistance of Klebsiella pneumoniae strains associated with porin OmpK36 loss and DHA-1 β-lactamase production

  2013cited by this paper
• Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance

  2012cited by this paper
• Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

  2011cited by this paper
• The RpoS-mediated general stress response in Escherichia coli.

  2011cited by this paper
• Persistence of antibiotic resistance in bacterial populations.

  2011cited by this paper
• The uncertain consequences of transferring bacterial strains between laboratories - rpoS instability as an example

  2011cited by this paper
• Antibiotic resistance and its cost: is it possible to reverse resistance?

  2010cited by this paper
• The evolution of antibiotic resistance: insight into the roles of molecular mechanisms of resistance and treatment context.

  2010cited by this paper
• Bridging timescales and length scales: from macroscopic flux to the molecular mechanism of antibiotic diffusion through porins.

  2010cited by this paper
• Global regulation by the seven-component Pi signaling system.

  2010cited by this paper
• Compensation of Fitness Costs and Reversibility of Antibiotic Resistance Mutations

  2010cited by this paper
• Impact of the RNA chaperone Hfq on multidrug resistance in Escherichia coli.

  2010cited by this paper
• A genetic approach for finding small RNAs regulators of genes of interest identifies RybC as regulating the DpiA/DpiB two‐component system

  2009cited by this paper
• The Fitness Cost of Streptomycin Resistance Depends on rpsL Mutation, Carbon Source and RpoS (σS)

  2009cited by this paper
• Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target.

  2009cited by this paper
• Outer membrane permeability and antibiotic resistance.

  2009cited by this paper
• Switching off small RNA regulation with trap‐mRNA

  2009cited by this paper
• A conserved small RNA promotes silencing of the outer membrane protein YbfM

  2009cited by this paper
• The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis.

  2008cited by this paper
• Small RNAs controlling outer membrane porins.

  2007cited by this paper
• Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli

  2006cited by this paper
• Two-Component Systems of Corynebacterium glutamicum: Deletion Analysis and Involvement of the PhoS-PhoR System in the Phosphate Starvation Response

  2006cited by this paper
• Novel gene members in the Pho regulon of Escherichia coli.

  2006cited by this paper
• Modulating the outer membrane with small RNAs.

  2006cited by this paper
• High-Level Carbapenem Resistance in a Klebsiella pneumoniae Clinical Isolate Is Due to the Combination of blaACT-1 β-Lactamase Production, Porin OmpK35/36 Insertional Inactivation, and Down-Regulation of the Phosphate Transport Porin PhoE

  2006cited by this paper
• Crystal structure of osmoporin OmpC from E. coli at 2.0 A.

  2006cited by this paper
• Crystal structure of the monomeric porin OmpG.

  2006cited by this paper
• Co-selection of antibiotic and metal resistance.

  2006cited by this paper
• Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation.

  2006cited by this paper
• Small non-coding RNAs and the bacterial outer membrane.

  2006cited by this paper
• Mutations Conferring Aminoglycoside and Spectinomycin Resistance in Borrelia burgdorferi

  2006cited by this paper
• Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research.

  2006cited by this paper
• Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

  2006cited by this paper
• Inactivation of the Pst System Reduces the Virulence of an Avian Pathogenic Escherichia coli O78 Strain

  2005cited by this paper
• Survivability of vancomycin resistant enterococci and fitness cost of vancomycin resistance acquisition

  2005cited by this paper
• Maintaining a healthy SPANC balance through regulatory and mutational adaptation

  2005cited by this paper
• A differential effect of σS on the expression of the PHO regulon genes of Escherichia coli

  2004cited by this paper
• Microscopic Mechanism of Antibiotics Translocation through a Porin.

  2004cited by this paper
• A differential effect of sigmaS on the expression of the PHO regulon genes of Escherichia coli.

  2004cited by this paper
• Global analysis of small RNA and mRNA targets of Hfq

  2003cited by this paper
• Constitutive Activation of the Escherichia coli Pho Regulon Upregulates rpoS Translation in an Hfq-Dependent Fashion

  2003cited by this paper
• Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.

  2002cited by this paper
• The Pho Regulons of Bacteria

  2002cited by this paper
• Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction.

  2001cited by this paper
• Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria.

  2000cited by this paper
• One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.

  2000cited by this paper
• De Novo peptide sequencing by nanoelectrospray tandem mass spectrometry using triple quadrupole and quadrupole/time-of-flight instruments.

  2000cited by this paper
• Substitutions in the Eyelet Region Disrupt Cefepime Diffusion through the Escherichia coli OmpF Channel

  2000cited by this paper
• PhoB-dependent transcriptional activation of the iciA gene during starvation for phosphate in Escherichia coli

  1999cited by this paper
• The Acid-Inducible asr Gene inEscherichia coli: Transcriptional Control by thephoBR Operon

  1999cited by this paper
• The biological cost of antibiotic resistance.

  1999cited by this paper
• Bacterial evolution and the cost of antibiotic resistance.

  1998cited by this paper
• Biochemistry and Regulation of a NovelEscherichia coli K-12 Porin Protein, OmpG, Which Produces Unusually Large Channels

  1998cited by this paper
• Identification and characterization of two quiescent porin genes, nmpC and ompN, in Escherichia coli BE.

  1998cited by this paper
• Identification and Characterization of Two Quiescent Porin Genes, nmpC and ompN, inEscherichia coli BE

  1998cited by this paper
• Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin.

  1997cited by this paper
• Global analysis of proteins synthesized during phosphorus restriction in Escherichia coli

  1996cited by this paper
• Prevalence of outer membrane porin alteration in beta-lactam-antibiotic-resistant Enterobacter aerogenes

  1996cited by this paper
• Identification of a mutation in the pst-phoU operon that reduces pathogenicity of an Escherichia coli strain causing septicemia in pigs

  1995cited by this paper
• The structure of OmpF porin in a tetragonal crystal form.

  1995cited by this paper
• The chromosomal response regulatory gene chvI of Agrobacterium tumefaciens complements an Escherichia coli phoB mutation and is required for virulence

  1993cited by this paper
• Crystal structures explain functional properties of two E. coli porins

  1992cited by this paper
• Isolation and characterization of adhesin-defective TnphoA mutants of septicaemic porcine Escherichia coli of serotype O115:K-:F165.

  1992cited by this paper
• Characterization of a polysaccharide capsular antigen of septicemic Escherichia coli O115:K "V165" :F165 and evaluation of its role in pathogenicity

  1992cited by this paper
• Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo

  1991cited by this paper
• A novel mutation, cog, which results in production of a new porin protein (OmpG) of Escherichia coli K-12

  1989cited by this paper
• Existence and purification of porin heterotrimers of Escherichia coli K12 OmpC, OmpF, and PhoE proteins.

  1989cited by this paper
• Isolation and characterization of deletion mutants of ompR and envZ, regulatory genes for expression of the outer membrane proteins OmpC and OmpF in Escherichia coli.

  1987cited by this paper
• Porin channels in Escherichia coli: studies with liposomes reconstituted from purified proteins

  1983cited by this paper
• Genetic analysis of the major outer membrane proteins of Escherichia coli.

  1981cited by this paper
• Genetic locus (ompB) affecting a major outer-membrane protein in Escherichia coli K-12

  1977cited by this paper

• Variations in carbapenem resistance associated with the VIM-1 metallo-β-lactamase across the Enterobacterales

  2026cites this paper
• Neisseria meningitidis serogroup W ST-4821 clonal complex shares a highly conserved capsular switching pattern with ST-11 clonal complex strains.

  2026cites this paper
• “Global divide in carbapenem resistance and hypervirulence of Klebsiella pneumonia: comparing trends in India and developed nations”- a comprehensive review

  2025cites this paper
• Drug delivery dynamics dictate evolution of bacterial antibiotic responses

  2025cites this paper
• The Role of the Hfq Protein in Bacterial Resistance to Antibiotics: A Narrative Review

  2025cites this paper
• Profile of outer membrane proteins of carbapenem-resistant Gram-negative bacilli in Ghana

  2025cites this paper
• Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae

  2025cites this paper
• Variations in carbapenem resistance associated with the VIM-1 metallo-β-lactamase across the Enterobacterales

  2025influential citation
• Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

  2024cites this paper
• Membrane anchoring of New Delhi metallo‐β‐lactamase‐1 alters the fitness of Escherichia coli and increases its susceptibility to colistin by inducing outer membrane destabilization

  2024cites this paper
• Gut microbiota-derived butyrate selectively interferes with growth of carbapenem-resistant Escherichia coli based on their resistance mechanism

  2024cites this paper
• Compensatory evolution of chromosomes and plasmids counteracts the plasmid fitness cost

  2024cites this paper
• Investigation of the impact of widely used pesticides on conjugative transfer of multidrug resistance plasmids.

  2024cites this paper
• Gene knockout studies of Dps protein reveals a novel role for DNA-binding protein in maintaining outer membrane permeability

  2024cites this paper
• The Effect of the Stringent Response and Oxidative Stress Response on Fitness Costs of De Novo Acquisition of Antibiotic Resistance

  2024cites this paper
• Comprehensive analysis of disinfectants on the horizontal transfer of antibiotic resistance genes.

  2023cites this paper
• Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteria

  2023cites this paper
• Chance Favors the Prepared Genomes: Horizontal Transfer Shapes the Emergence of Antibiotic Resistance Mutations in Core Genes

  2023cites this paper
• Perturbation and mechanism of non-antibiotic drug in regulating resistome and metabolome of anammox consortia: An overlooked and underrated cause of multiresistance

  2023cites this paper
• Horizontal transfer and driving factors of extended-spectrum β-lactamase-producing resistance genes in mice intestine after the ingestion of contaminated water

  2023cites this paper
• Identification of combinatorial mutations associated with colistin resistance in Shewanella algae.

  2023cites this paper
• Predicting MmpR-based bedaquiline resistance using sequence- and structure-based features

  2022cites this paper
• Transmembrane β-barrel proteins of bacteria: From structure to function.

  2022cites this paper
• The Resistance Mechanism Governs Physiological Adaptation of Escherichia coli to Growth With Sublethal Concentrations of Carbapenem

  2022cites this paper
• Liquid Chromatography-Tandem Mass Spectrometry Analysis Demonstrates a Decrease in Porins and Increase in CMY-2 β-Lactamases in Escherichia coli Exposed to Increasing Concentrations of Meropenem

  2022cites this paper
• Systematic Analysis of Mobile Genetic Elements Mediating β-Lactamase Gene Amplification in Noncarbapenemase-Producing Carbapenem-Resistant Enterobacterales Bloodstream Infections

  2022cites this paper
• A Snapshot of Antibiotic Resistances in Air Particulate of a Provincial Capital City, Indonesia

  2022cites this paper
• High Osmotic Stress Increases OmpK36 Expression through the Regulation of KbvR to Decrease the Antimicrobial Resistance of Klebsiella pneumoniae

  2022cites this paper
• Effect of sulfamethazine on the horizontal transfer of plasmid-mediated antibiotic resistance genes and its mechanism of action.

  2022cites this paper
• Proteomics profiling of ertapenem challenged major porin deficient carbapenem-resistant Klebsiella pneumoniae.

  2022cites this paper
• Identification of combinatorial colistin resistance mutations in Shewanella algae

  2022cites this paper
• Structural Diversity, Fitness Cost, and Stability of a BlaNDM-1-Bearing Cointegrate Plasmid in Klebsiella pneumoniae and Escherichia coli

  2021cites this paper
• Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics

  2021cites this paper
• Efflux Transporters' Engineering and Their Application in Microbial Production of Heterologous Metabolites.

  2021cites this paper
• Molecular Mechanisms of Genetic Interaction (Epistasis) in the Evolution and Management of Antibiotic Resistance Tuberculosis: Current Consequence and Future Perspectives

  2021cites this paper
• Differential Expression of Yersinia pseudotuberculosis General Porin Genes during Short- and Long-Term Antibiotic Stresses

  2021cites this paper
• Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

  2021cites this paper
• Paclitaxel and its derivative facilitate the transmission of plasmid-mediated antibiotic resistance genes through conjugative transfer.

  2021cites this paper
• Piperacillin-Tazobactam-Resistant/Third-Generation Cephalosporin-Susceptible Escherichia coli and Klebsiella pneumoniae Isolates: Resistance Mechanisms and In vitro-In vivo Discordance.

  2020cites this paper
• An Intertwined Network of Regulation Controls Membrane Permeability Including Drug Influx and Efflux in Enterobacteriaceae

  2020cites this paper
• Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli

  2020cites this paper
• Stress responses, outer membrane permeability control and antimicrobial resistance in Enterobacteriaceae 2 3

  2020cites this paper
• Antibiotic resistance: turning evolutionary principles into clinical reality.

  2020cites this paper
• Glyphosate escalates horizontal transfer of conjugative plasmid harboring antibiotic resistance genes

  2020cites this paper
• Le rôle des porines dans la résistance aux antibiotiques

  2020cites this paper
• Preservatives accelerate the horizontal transfer of plasmid-mediated antimicrobial resistance genes via differential mechanisms.

  2020cites this paper
• Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

  2019cites this paper
• Outer Membrane Porins.

  2019cites this paper
• Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

  2019cites this paper
• Characterizing and exploiting genetic trajectories towards antibiotic resistance

  2019cites this paper
• Genetic Adaptation to Growth Under Laboratory Conditions in Escherichia coli and Salmonella enterica

  2018cites this paper
• Stress responses, outer membrane permeability control and antimicrobial resistance in Enterobacteriaceae.

  2018cites this paper
• Chromosomal barcoding as a tool for multiplexed phenotypic characterization of laboratory evolved lineages

  2018cites this paper
• Evolution Underway in Prokaryotes

  2018cites this paper
• Host adaptation and convergent evolution increases antibiotic resistance without loss of virulence in a major human pathogen

  2018cites this paper
• Epidemiology of Bloodstream Infections Caused by Escherichia coli and Klebsiella pneumoniae That Are Piperacillin-Tazobactam-Nonsusceptible but Ceftriaxone-Susceptible

  2018cites this paper
• Carbapenem Resistance Caused by High-Level Expression of OXA-663 β-Lactamase in an OmpK36-Deficient Klebsiella pneumoniae Clinical Isolate

  2018cites this paper
• Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1477 Mechanisms of Antibiotic Resistance Evolution

  2018cites this paper
• A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

  2018cites this paper
• Genomic and functional characterisation of IncX3 plasmids encoding blaSHV-12 in Escherichia coli from human and animal origin

  2018cites this paper
• Predictable Phenotypes of Antibiotic Resistance Mutations

  2018cites this paper
• Potential and use of bacterial small RNAs to combat drug resistance: a systematic review

  2017cites this paper
• Epistasis and the Evolution of Antimicrobial Resistance

  2017cites this paper
• Altered Outer Membrane Transcriptome Balance with AmpC Overexpression in Carbapenem-Resistant Enterobacter cloacae

  2016cites this paper
• Short-term evolution of antibiotic responses in highly dynamic environments favors loss of regulation.

  year unknowncites this paper
• Rapid decline of bacterial drug-resistance in an antibiotic-1 free environment through phenotypic reversion 2 3

  year unknowncites this paper
• Acta Universitatis Upsaliensis Uppsala 2016

  year unknowncites this paper