The Role of Isoflavones in Menopausal Health: Consensus Opinion of The North American Menopause Society

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Menopause

• Publication date

  2000-07-20

• Fields of study

  Medicine

• Identifiers
  PMID 10914614
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat.

  2008cited by this paper
• Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women.

  1999cited by this paper
• Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women.

  1999cited by this paper
• Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women.

  1999cited by this paper
• The effect of Promensil, an isoflavone extract, on menopausal symptoms.

  1999cited by this paper
• Phytoestrogens inhibit growth and MAP kinase activity in human aortic smooth muscle cells.

  1999cited by this paper
• Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage.

  1999cited by this paper
• Soy isoflavones exert modest hormonal effects in premenopausal women.

  1999cited by this paper
• Soybean isoflavones reduce experimental metastasis in mice.

  1999cited by this paper
• Isoflavones and postmenopausal bone health: a viable alternative to estrogen therapy?

  1999cited by this paper
• Dietary isoflavones: biological effects and relevance to human health.

  1999cited by this paper
• Expression and Localization of Estrogen Receptor‐β in Murine and Human Bone

  1999cited by this paper
• Intact dietary soy protein, but not adding an isoflavone-rich soy extract to casein, improves plasma lipids in ovariectomized cynomolgus monkeys.

  1999cited by this paper
• Effect of estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth factor mRNAs in the frontal cortex and hippocampus of female rats.

  1999cited by this paper
• Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast.

  1999cited by this paper
• Usual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in Shanghai.

  1999cited by this paper
• Effects of isoflavonoids on blood pressure in subjects with high-normal ambulatory blood pressure levels: a randomized controlled trial.

  1999cited by this paper
• Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta.

  1999cited by this paper
• Effects of dietary phytoestrogens in postmenopausal women.

  1998cited by this paper
• Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.

  1998cited by this paper
• In vivo toxicity, pharmacokinetics, and anticancer activity of Genistein linked to recombinant human epidermal growth factor.

  1998cited by this paper
• The Effect of Dietary Soy Supplementation on Hot Flushes

  1998cited by this paper
• Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice.

  1998cited by this paper
• Chemoprevention of N‐Nitroso‐N‐methylurea‐induced Rat Mammary Cancer by Miso and Tamoxifen, Alone and in Combination

  1998cited by this paper
• Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones.

  1998cited by this paper
• Age-related deterioration in arterial structure and function in postmenopausal women: impact of hormone replacement therapy.

  1998cited by this paper
• Reproductive actions of phytoestrogens.

  1998cited by this paper
• Inhibition of murine bladder tumorigenesis by soy isoflavones via alterations in the cell cycle, apoptosis, and angiogenesis.

  1998cited by this paper
• Soy intake and risk of breast cancer in Asians and Asian Americans.

  1998cited by this paper
• Increased expression of estrogen receptor-beta mRNA in male blood vessels after vascular injury.

  1998cited by this paper
• Coronary artery and cultured aortic smooth muscle cells express mRNA for both the classical estrogen receptor and the newly described estrogen receptor beta.

  1998cited by this paper
• Japanese intake of flavonoids and isoflavonoids from foods.

  1998cited by this paper
• Bone-sparing effect of soy protein in ovarian hormone-deficient rats is related to its isoflavone content.

  1998cited by this paper
• Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

  1998cited by this paper
• Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance.

  1998cited by this paper
• Inhibition of human bladder cancer cell motility by genistein is dependent on epidermal growth factor receptor but not p21ras gene expression

  1998cited by this paper
• Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat.

  1998cited by this paper
• The North American Menopause Society develops consensus opinions.

  1998cited by this paper
• Evolution of the Health Benefits of Soy Isoflavones

  1998cited by this paper
• Genistein Alters the Ontogeny of Mammary Gland Development and Protects Against Chemically-Induced Mammary Cancer in Rats

  1998cited by this paper
• Phyto-oestrogens and breast cancer.

  1998cited by this paper
• Effect of isoflavones genistein and daidzein in the inhibition of lung metastasis in mice induced by B16F-10 melanoma cells.

  1998cited by this paper
• Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast.

  1998cited by this paper
• Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence.

  1998cited by this paper
• Effects of mammalian and plant estrogens on mammary glands and uteri of macaques.

  1998cited by this paper
• Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women.

  1998cited by this paper
• Biphasic Effects of Genistein on Bone Tissue in the Ovariectomized, Lactating Rat Model

  1998cited by this paper
• Soy Protein Isolate Diet Does Not Prevent Increased Cortical Bone Turnover in Ovariectomized Macaques

  1998cited by this paper
• Preventive effects of the plant isoflavones, daidzin and genistin, on bone loss in ovariectomized rats fed a calcium-deficient diet.

  1998cited by this paper
• The North American Menopause Society develops consensus opinions.

  1998cited by this paper
• Phytoestrogens and breast cancer.

  1998cited by this paper
• Comparative distribution of estrogen receptor‐α and ‐β mRNA in the rat central nervous system

  1997cited by this paper
• Soy isoflavones improve systemic arterial compliance but not plasma lipids in menopausal and perimenopausal women.

  1997cited by this paper
• Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.

  1997cited by this paper
• Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system.

  1997cited by this paper
• Soy protein versus soy phytoestrogens in the prevention of diet-induced coronary artery atherosclerosis of male cynomolgus monkeys.

  1997cited by this paper
• Association of soy and fiber consumption with the risk of endometrial cancer.

  1997cited by this paper
• Genistein, the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL.

  1997cited by this paper
• Case-control study of phyto-oestrogens and breast cancer.

  1997cited by this paper
• Short‐term Effects of Phytoestrogen‐rich Diet on Postmenopausal Women

  1997cited by this paper
• Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones.

  1996cited by this paper
• Molecular effects of genistein on estrogen receptor mediated pathways.

  1996cited by this paper
• Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats.

  1996cited by this paper
• Effects of hormone therapy on bone mineral density: results from the postmenopausal estrogen/progestin interventions (PEPI) trial. The Writing Group for the PEPI.

  1996cited by this paper
• Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women.

  1996cited by this paper
• Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats

  1996cited by this paper
• Tofu and risk of breast cancer in Asian-Americans.

  1996cited by this paper
• Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.

  1996cited by this paper
• Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial.

  1995cited by this paper
• Soy and experimental cancer: animal studies.

  1995cited by this paper
• Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women.

  1995cited by this paper
• Meta-analysis of the effects of soy protein intake on serum lipids.

  1995cited by this paper
• Phytoestrogen Content and Estrogenic Effect of Legume Fodder

  1995cited by this paper
• Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases

  1995cited by this paper
• Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial

  1995cited by this paper
• Formation of polyhydroxylated isoflavones from the soybean seed isoflavones daidzein and glycitein by bacteria isolated from tempe

  1995cited by this paper
• Differential effects of estrogen treatment on bone mineral density of the spine, hip, wrist and total body in late postmenopausal women

  1995cited by this paper
• Racial differences in hip axis lengths might explain racial differences in rates of hip fracture

  1994cited by this paper
• The climacteric of Chinese factory workers.

  1994cited by this paper
• Intake of 25 g of soybean protein with or without soybean fiber alters plasma lipids in men with elevated cholesterol concentrations.

  1994cited by this paper
• Isoflavone content in commercial soybean foods

  1994cited by this paper
• Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women.

  1994cited by this paper
• Tofu and soy drinks contain phytoestrogens.

  1994cited by this paper
• Isoflavones and their conjugates in soy foods: extraction conditions and analysis by HPLC-mass spectrometry

  1994cited by this paper
• Potential role of dietary isoflavones in the prevention of cancer.

  1994cited by this paper
• Depression of plasma cholesterol in men by consumption of baked products containing soy protein.

  1993cited by this paper
• Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

  1993cited by this paper
• The role of soy products in reducing risk of cancer.

  1991cited by this paper
• Dietary effects on breast-cancer risk in Singapore.

  1991cited by this paper
• Dietary soybean isolate and methionine supplementation affect mammary tumor progression in rats.

  1991cited by this paper
• Soybeans inhibit mammary tumors in models of breast cancer.

  1990cited by this paper
• Western diet and Western diseases: some hormonal and biochemical mechanisms and associations.

  1990cited by this paper
• Cancers of the breast, endometrium and ovary: geographic correlations.

  1989cited by this paper
• Metabolism of ipriflavone (TC-80) in rats.

  1985cited by this paper
• Soybean isoflavones: effect of environment and variety on composition.

  1983cited by this paper
• Phytoestrogen content of processed soybean products

  1982cited by this paper
• Binding of phyto-oestrogen and oestradiol-17 beta by cytoplasmic receptors in the pituitary gland and hypothalamus of the ewe.

  1980cited by this paper
• Phytoestrogen interaction with estrogen receptors in human breast cancer cells.

  1978cited by this paper
• Variation of the human menstrual cycle through reproductive life.

  1967cited by this paper

• Estradiol metabolism by gut microbiota in women’s depression pathogenesis: inspiration from nature

  2025cites this paper
• Mechanism of action of genistein on breast cancer and differential effects of different age stages

  2025cites this paper
• Osteoprotective Effect of the Phytonutraceutical Ormona® on Ovariectomy-Induced Osteoporosis in Wistar Rats

  2024cites this paper
• Optimizing menopausal hormone therapy: for treatment and prevention, menstrual regulation, and reduction of possible risks

  2022cites this paper
• Utilization of Isoflavones in Soybeans for Women with Menopausal Syndrome: An Overview

  2021cites this paper
• Trifolium Species

  2020cites this paper
• Isoflavones in gynecology, non-conventional therapy

  2020cites this paper
• Isoflavone Supplements for Menopausal Women: A Systematic Review

  2019cites this paper
• The history and basic science development of soy isoflavones

  2017cites this paper
• Revisión de conjunto Fitoestrógenos: conocimientos básicos y utilidad clínica

  2016cites this paper
• Soybean Isoflavones Warrant Greater Consideration as a Treatment for the Alleviation of Menopausal Hot Flashes

  2014cites this paper
• Endometrial, breast and liver safety of soy isoflavones plus Lactobacillus sporogenes in post-menopausal women

  2013cites this paper
• AVALIAÇÃO DO POTENCIAL DOS FUNGOS DO GÊNERO Rhizopus spp NA PRODUÇÃO DE SUBSTÂNCIAS BIOATIVAS COM AÇÃO ANTIOXIDANTE UTILIZANDO DIFERENTES SUBSTRATOS

  2013cites this paper
• Do extracts of oral soybean augment the trophic effect of estrogen on the rat uterus?

  2012cites this paper
• Medikamentöse Therapiemöglichkeiten in der Menopause

  2011cites this paper
• Effect of methanolic soy extract on serum levels of lipid and lipoproteins in ovariectomized rats

  2011cites this paper
• Optimizing soy isoflavones effect in postmenopausal women: the impact of timing on climacteric symptoms

  2011cites this paper
• [Effects of high doses of genistein on mammary gland of female rat].

  2011cites this paper
• Effects of high-dose isoflavones on rat uterus.

  2011cites this paper
• Efeitos das isoflavonas em altas doses sobre o útero da rata

  2011cites this paper
• Phytotherapy as alternative to hormone replacement therapy.

  2011cites this paper
• Soy Isoflavones as Bioactive Ingredients of Functional Foods

  2011cites this paper
• Menopausale vasomotorische Symptome

  2010cites this paper
• Fermented Soy Product Isoflavone Composition, and Role in Gene Responses in C57BL/6 Mice

  2010cites this paper
• Roundoc Rx: Phytoestrogens

  2010cites this paper
• Avaliação do potencial antifúngico de própolis de Apis mellifera contra leveduras do gênero Candida

  2010cites this paper
• Abordaje, diagnstico y enfoques teraputicos de los sntomas vasomotores. Estudio LADIES

  2010cites this paper
• Isoflavone regulates vascular endothelial growth factor expression in urinary tract of castrated rats.

  2009cites this paper
• Alimentos fermentados à base de soja (Glycine max (Merrill) L.): importância econômica, impacto na saúde e efeitos associados às isoflavonas e seus açúcares

  2009cites this paper
• Guía para el manejo de los síntomas menopáusicos en mujeres con cáncer de mama

  2009cites this paper
• Phytoestrogens in peri-and postmenopause 184

  2009influential citation
• Effects of soy isoflavones on the uterus and urethra of ovariectomized rats

  2009cites this paper
• Position of the American Dietetic Association: Functional foods.

  2009cites this paper
• Natural Medications (Herbs, Vitamins, and Supplements) for Menopausal Symptoms

  2008cites this paper
• Posicionamiento de la Asociación Española para el Estudio de la Menopausia sobre el uso clínico de las isoflavonas en el climaterio

  2008cites this paper
• 1-(5-Chloro-2,4-dihydroxyphenyl)-2-(4-ethoxyphenyl)ethanone

  2008cites this paper
• Human Nutrition Value of Soybean Oil and Soy Protein

  2008cites this paper
• Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary

  2008cites this paper
• Nutrient Intake and Effects of Isoflavone Supplementation on Bone Mineral Density in Female College Students with Osteopenia

  2008cites this paper
• Nahrungsergänzungsmittel im Klimakterium

  2008cites this paper
• In vitro estrogenic activity of Achillea millefolium L.

  2007cites this paper
• Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women

  2007cites this paper
• Alternative Therapiemöglichkeiten zur Hormontherapie in der Postmenopause

  2007cites this paper
• Efficacy and safety of a soy isoflavone extract in postmenopausal women: a randomized, double-blind, and placebo-controlled study.

  2007cites this paper
• zur Hormontherapie in der Postmenopause

  2007cites this paper
• Effect of a compound containing isoflavones, primrose oil and vitamin E in two different doses on climacteric symptoms

  2006cites this paper
• Management of osteoporosis in postmenopausal women: 2006 position statement of The North American Menopause Society

  2006cites this paper
• The Effects of a Multimodal Intervention Trial to Promote Lifestyle Factors Associated With the Prevention of Cardiovascular Disease in Menopausal and Postmenopausal Australian Women

  2006cites this paper
• Psychological well-being improves in women with breast cancer after treatment with applied relaxation or electro-acupuncturefor vasomotor symptom

  2006cites this paper
• THE BENEFITS OF SOY IS SOY SAFE ?

  2006cites this paper
• Randomized clinical trial comparing conjugated equine estrogens and isoflavones in postmenopausal women: a pilot study.

  2006cites this paper
• Isoflavone und das Endometrium

  2006cites this paper
• Herbal Medicines in Pregnancy and Lactation: An Evidence-Based Approach

  2006cites this paper
• Dermoscopic patterns as predictors of sentinel lymph node metastasization in cutaneous melanoma

  2006cites this paper
• Phytoestrogens and the menopause – do they really help?

  2005cites this paper
• Phytoestrogens: End of a tale?

  2005cites this paper
• Title: The effects of a multi-modal intervention trial to promote lifestyle factors associated with the prevention of cardio-vascular disease in menopausal and post menopausal Australian women.

  2005cites this paper
• Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?

  2005cites this paper
• Soy and health 2004: clinical evidence, dietetic applications

  2005cites this paper
• The effect of red clover isoflavones on menopausal symptoms, lipids and vaginal cytology in menopausal women: A randomized, double-blind, placebo-controlled study

  2005cites this paper
• Isoflavones, protein, and bone 1,2

  2005cites this paper
• Isoflavones, protein, and bone.

  2005cites this paper
• The acceptability of isoflavones as a treatment of menopausal symptoms: a European survey among postmenopausal women

  2005cites this paper
• Red clover isoflavones and menopausal health.

  2004cites this paper
• Perimenopause: an update.

  2004cites this paper
• Hormone Therapy after Endometrial Cancer

  2004cites this paper
• Isoflavonas en ginecología, terapia no convencional

  2004cites this paper
• Synthesis of [3,4,8-13C3]daidzein

  2004cites this paper
• The role of complementary and alternative medicine in management of menopausal symptoms.

  2004cites this paper
• Hormone therapy after endometrial cancer.

  2004cites this paper
• Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society.

  2004cites this paper
• Hormone Therapy after Endometrial Cancer

  2004cites this paper
• Phytoestrogens for osteoporosis

  2004cites this paper
• Dietary Supplements for Health Maintenance and Risk Factor Reduction

  2004cites this paper
• The Role of Phytoestrogens as Cancer Prevention Agents

  2004cites this paper
• Isoflavones and bone health.

  2004cites this paper
• Risks and benefits of soy isoflavones for breast cancer survivors.

  2004cites this paper
• [Peri-menopausal and post-menopausal experience among women with and without hormone replacement therapy].

  2004cites this paper
• Influence of marketed herbal menopause preparations on MCF-7 cell proliferation

  2004cites this paper
• The effect of a soy rich diet on the vaginal epithelium in postmenopause: a randomized double blind trial.

  2003cites this paper
• Hormone therapy after endometrial cancer

  2003cites this paper
• Isoflavone Supplements Do Not Affect Thyroid Function in Iodine-Replete Postmenopausal Women

  2003cites this paper
• Estrogen--no matter how delivered--relieves postmenopausal vasomotor symptoms.

  2003cites this paper
• Morning/Evening Menopausal Formula Relieves Menopausal Symptoms: A Pilot Study

  2003cites this paper
• Phytoestrogens: Potential Benefits and Implications for Breast Cancer Survivors

  2003cites this paper
• What we know about managing menopausal hot flashes: navigating without a compass.

  2003cites this paper
• The menopause and HRT. Prevention and management of osteoporosis.

  2003cites this paper
• Nutrition and Lifestyle Factors on the Risk of Developing Breast Cancer

  2003cites this paper
• Investigating the role of natural phyto-oestrogens on bone health in postmenopausal women

  2003cites this paper
• Der Stellenwert von Phytoestrogenen in der Therapie des klimakterischen Syndroms

  2003cites this paper
• The Use of Complementary and Alternative Therapies in Older Women

  2003cites this paper
• Managing Menopause Naturally

  2003cites this paper
• Prevention and management of osteoporosis

  2003cites this paper
• Persönlicher Lebensstil und Brustkrebsrisiko

  2003cites this paper
• Dietary soy protein maintains some indices of bone mineral density and bone formation in aged ovariectomized rats.

  2003cites this paper
• Avaliação do teor de isoflavonas de "suplementos nutricionais à base de soja"

  2003cites this paper
• Efficacy of Soyfoods and Soybean Isoflavone Supplements for Alleviating Menopausal Symptoms Is Positively Related to Initial Hot Flush Frequency

  2003cites this paper
• Isoflavones and skeletal health: are these molecules ready for clinical application?

  2003cites this paper
• Senkung des Brustkrebsrisikos

  2003cites this paper
• Effect of Soy Supplementation on Endogenous Hormones in Postmenopausal Women

  2003cites this paper