Impaired cortico-striatal functional connectivity in prodromal Huntington's Disease.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Neuroscience Letters

• Publication date

  2012-04-18

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/j.neulet.2012.02.095PMID 22425717PMCID PMC3331724
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease

  2012cited by this paper
• Connectivity-based segmentation of the striatum in Huntington's disease: vulnerability of motor pathways.

  2011cited by this paper
• On the relationship between seed‐based and ICA‐based measures of functional connectivity

  2011cited by this paper
• Huntington's disease: from molecular pathogenesis to clinical treatment

  2011influential reference
• Brain networks in Huntington disease.

  2011cited by this paper
• Analysis of the Striato-Thalamo-Cortical Connectivity on the Cortical Surface to Infer Biomarkers of Huntington's Disease

  2010cited by this paper
• Huntington disease

  2010cited by this paper
• Disease and the brain's dark energy

  2010cited by this paper
• Intrinsic functional connectivity as a tool for human connectomics: theory, properties, and optimization.

  2010cited by this paper
• Longitudinal change in regional brain volumes in prodromal Huntington disease

  2010cited by this paper
• Tongue force analysis assesses motor phenotype in premanifest and symptomatic Huntington's disease

  2010cited by this paper
• Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease.

  2010cited by this paper
• Two views of brain function.

  2010cited by this paper
• Functional imaging in Huntington's disease.

  2009cited by this paper
• Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease

  2009cited by this paper
• Functional compensation of motor function in pre-symptomatic Huntington's disease

  2009cited by this paper
• Aberrant connectivity of lateral prefrontal networks in presymptomatic Huntington's disease.

  2008cited by this paper
• Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity.

  2008cited by this paper
• Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging

  2007cited by this paper
• Topology-Preserving Tissue Classification of Magnetic Resonance Brain Images

  2007cited by this paper
• Huntington's disease

  2007cited by this paper
• The corticostriatal pathway in Huntington's disease.

  2007cited by this paper
• Huntington's disease.

  2007cited by this paper
• Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease.

  2007cited by this paper
• Brain structure in preclinical Huntington's disease.

  2006cited by this paper
• Consistent resting-state networks across healthy subjects

  2006cited by this paper
• The human brain is intrinsically organized into dynamic, anticorrelated functional networks.

  2005cited by this paper
• Functional brain changes in presymptomatic Huntington's disease

  2004cited by this paper
• A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length

  2004cited by this paper
• Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest

  2004cited by this paper
• Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study.

  2003cited by this paper
• Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment.

  2003cited by this paper
• Open interconnected model of basal ganglia‐thalamocortical circuitry and its relevance to the clinical syndrome of Huntington's disease

  2001cited by this paper
• Rate of functional decline in Huntington’s disease

  2000cited by this paper
• Huntington disease.

  1998cited by this paper
• CAG repeat number governs the development rate of pathology in Huntington's disease

  1997cited by this paper
• Longitudinal change in basal ganglia volume in patients with Huntington's disease

  1997cited by this paper
• Limbic-cortical dysregulation: a proposed model of depression.

  1997cited by this paper
• Trinucleotide repeat length and clinical progression in Huntington's disease

  1996cited by this paper
• Functional connectivity in the motor cortex of resting human brain using echo‐planar mri

  1995cited by this paper
• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

  1993cited by this paper
• Functional Connectivity: The Principal-Component Analysis of Large (PET) Data Sets

  1993cited by this paper
• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

  1993cited by this paper
• Paralimbic frontal lobe hypometabolism in depression associated with Huntington's disease

  1992cited by this paper
• Declaration of Helsinki.

  1991cited by this paper
• Declaration of Helsinki

  1990cited by this paper
• Parallel organization of functionally segregated circuits linking basal ganglia and cortex.

  1986cited by this paper
• Huntington's disease

  1984cited by this paper
• The measurement of abnormal movement: methods developed for Huntington's disease.

  1983cited by this paper
• Huntington's disease.

  1982cited by this paper
• A Simple Sequentially Rejective Multiple Test Procedure

  1979cited by this paper
• DECLARATION OF HELSINKI.

  1964cited by this paper
• FREQUENCY DISTRIBUTION OF THE VALUES OF THE CORRELATION COEFFIENTS IN SAMPLES FROM AN INDEFINITELY LARGE POPU;ATION

  1915cited by this paper
• See Blockindiscussions, Blockinstats, Blockinand Blockinauthor Blockinprofiles Blockinfor Blockinthis Blockinpublication

  year unknowncited by this paper

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  2026cites this paper
• Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease

  2025cites this paper
• Large Scale Functional and Effective Connectivity Alterations cross the Huntington’s Disease Integrated Staging System

  2025cites this paper
• Optogenetics and Its Application in Nervous System Diseases

  2025cites this paper
• Striato-cortical connectivity patterns predict clinical profiles in Huntington’s disease

  2025cites this paper
• Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

  2025cites this paper
• Neural Mechanisms of Object Location Memory in Huntington's Disease

  2025cites this paper
• Photoactivated adenylyl cyclase in cortical astrocytes promotes synaptic potentiation and reveals alterations in Huntington’s disease

  2025cites this paper
• The contribution of preclinical magnetic resonance imaging and spectroscopy to Huntington’s disease

  2024cites this paper
• Postmortem neuropathology in early Huntington disease

  2024cites this paper
• Neuroimaging to Facilitate Clinical Trials in Huntington’s Disease: Current Opinion from the EHDN Imaging Working Group

  2024cites this paper
• Methylphenidate differentially alters corticostriatal connectivity after traumatic brain injury

  2024cites this paper
• Selective vulnerability of layer 5a corticostriatal neurons in Huntington's disease.

  2024cites this paper
• Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

  2023influential citation
• Multiple neuron clusters on Micro-Electrode Arrays as an in vitro model of brain network

  2023cites this paper
• Disrupted functional connectivity of the striatum in patients with diffuse axonal injury: a resting-state functional MRI study

  2023cites this paper
• Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington’s disease

  2023cites this paper
• Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington’s Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain

  2023cites this paper
• Local synchronicity in dopamine-rich caudate nucleus influences Huntington's disease motor phenotype.

  2023cites this paper
• Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease.

  2023cites this paper
• M2 Cortex Circuitry and Sensory-Induced Behavioral Alterations in Huntington's Disease: Role of Superior Colliculus

  2023influential citation
• Resting-State fMRI reveals Longitudinal Alterations in Brain Network Connectivity in a Mouse Model of Huntington’s Disease

  2022cites this paper
• Ex vivo 100 μm isotropic diffusion MRI‐based tractography of connectivity changes in the end‐stage R6/2 mouse model of Huntington's disease

  2022cites this paper
• Hunting for the cause: Evidence for prion-like mechanisms in Huntington’s disease

  2022cites this paper
• Cerebellar and basal ganglia motor network predicts trait depression and hyperactivity

  2022cites this paper
• Neurochemical correlates of synapse density in a Huntington's disease mouse model

  2022cites this paper
• Microglia Mediate Early Corticostriatal Synapse Loss and Cognitive Dysfunction in Huntington’s Disease Through Complement-Dependent Mechanisms

  2021cites this paper
• In vivo MR spectroscopy reflects synapse density in a Huntington’s disease mouse model

  2021cites this paper
• Synaptic Damage and Its Clinical Correlates in People With Early Huntington Disease

  2021cites this paper
• Altered Cortical-Striatal Network in Patients With Hemifacial Spasm

  2021cites this paper
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  2021cites this paper
• Bayesian random projection-based signal detection for Gaussian scale space random fields

  2021cites this paper
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  2021cites this paper
• Cortico‐striatal functional connectivity and cerebral small vessel disease: Contribution to mild Parkinsonian signs

  2021cites this paper
• M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease

  2020cites this paper
• Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.

  2020cites this paper
• Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate

  2020cites this paper
• Cortical and Striatal Circuits in Huntington’s Disease

  2020cites this paper
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  2020cites this paper
• Cerebellar-cortical function and connectivity during sensorimotor behavior in aging FMR1 gene premutation carriers

  2020cites this paper
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  2019cites this paper
• Differential Changes in Functional Connectivity of Striatum-Prefrontal and Striatum-Motor Circuits in Premanifest Huntington’s Disease

  2019cites this paper
• Aberrant brain network connectivity in presymptomatic and manifest Huntington's disease: A systematic review

  2019cites this paper
• Genetics of brain networks and connectivity

  2019cites this paper
• Cortical circuit alterations precede motor impairments in Huntington’s disease mice

  2019cites this paper
• Huntington's disease: Brain imaging in Huntington's disease.

  2019cites this paper
• Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation.

  2018cites this paper
• Whole-Brain Connectivity in a Large Study of Huntington's Disease Gene Mutation Carriers and Healthy Controls

  2018cites this paper
• Cognition and anatomy of adult Niemann–Pick disease type C: Insights for the Alzheimer field

  2018cites this paper
• Cortical circuit alterations precede disease onset in Huntington’s disease mice

  2018cites this paper
• Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors

  2018cites this paper
• Connectomic imaging reveals Huntington‐related pathological and pharmaceutical effects in a mouse model

  2018cites this paper
• Sleep-related modifications of EEG connectivity in the sensory-motor networks in Huntington Disease: An eLORETA study and review of the literature.

  2017cites this paper
• Cognition sociale dans la maladie de Huntington : etude cognitive et par imagerie cérébrale morphologique et fonctionnelle

  2017cites this paper
• Resting State Functional Connectivity of the Supplementary Motor Area and the Caudate Nucleus in Prodromal Huntington's Disease

  2017cites this paper
• Disrupted functional connectivity of striatal sub-regions in Bell's palsy patients

  2017cites this paper
• Resting‐state connectivity and modulated somatomotor and default‐mode networks in Huntington disease

  2017cites this paper
• Functional imaging in Huntington disease.

  2017cites this paper
• Computational psychiatry: Advancing predictive modeling of neurodegeneration with neuroimaging of Huntington's disease

  2017cites this paper
• Alterations of functional connectivity of the motor cortex in Fabry disease

  2017cites this paper
• Etude de la connectivité fonctionnelle dans les pathologies de mouvement de Parkinson et de Huntington en utilisant l’approche par graine et la théorie des graphes

  2017cites this paper
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  2017influential citation
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  2017cites this paper
• Striatal morphology correlates with frontostriatal electrophysiological motor processing in Huntington's disease: an IMAGE‐HD study

  2016influential citation
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  2016cites this paper
• Defining the distinction: neural and cognitive correlates of apathy & depression in prodromal huntington’s disease

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Induced Pluripotent Stem Cells in Huntington’s Disease Research: Progress and Opportunity

  2016cites this paper
• Longitudinal changes in functional connectivity of cortico‐basal ganglia networks in manifests and premanifest huntington's disease

  2016cites this paper
• Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF

  2016cites this paper
• Age-dependent alterations in the cortical entrainment of subthalamic nucleus neurons in the YAC128 mouse model of Huntington's disease.

  2015cites this paper
• Huntington's Disease for Brain Mapping: An Encyclopedic Reference

  2015cites this paper
• The role of the amygdala during emotional processing in Huntington's disease: From pre-manifest to late stage disease

  2015cites this paper
• Longitudinal resting state fMRI analysis in healthy controls and premanifest Huntington's disease gene carriers: A three‐year follow‐up study

  2015cites this paper
• Recent imaging advances in neurology

  2015cites this paper
• Effects of Pharmacological De-prenylation of Rhes on Motor Behavior in a Beta-Nitropropionic Acid Animal Model of Huntington's Disease

  2015influential citation
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  2015cites this paper
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  2015cites this paper
• Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease

  2015cites this paper
• Frontal cortex BOLD signal changes in premanifest Huntington disease

  2014cites this paper
• C9ORF72 hexanucleotide repeats in behavioral and motor neuron disease: clinical heterogeneity and pathological diversity.

  2014cites this paper
• Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects

  2014cites this paper
• Abnormal synchrony of resting state networks in premanifest and symptomatic Huntington disease: the IMAGE-HD study.

  2014cites this paper
• Neuroimaging in Huntington's disease.

  2014cites this paper
• Biomarker development for Huntington's disease.

  2014cites this paper
• Huntingtin Is Required for Normal Excitatory Synapse Development in Cortical and Striatal Circuits

  2014cites this paper
• Huntington disease: natural history, biomarkers and prospects for therapeutics

  2014cites this paper
• Functional Connectivity of Primary Motor Cortex Is Dependent on Genetic Burden in Prodromal Huntington Disease

  2014cites this paper
• Stimulation Therapies and the Relevance of Fractal Dynamics to the Treatment of Diseases

  2014cites this paper
• Brain connectivity in neurodegenerative diseases—from phenotype to proteinopathy

  2014cites this paper
• Abnormal resting-state connectivity of motor and cognitive networks in early manifest Huntington's disease

  2014influential citation
• Altered resting‐state connectivity in Huntington's Disease

  2014cites this paper
• Resting-state functional MR imaging: a new window to the brain.

  2014cites this paper
• Resting-state Functional mR imaging : A New Window to the Brain 1

  2014cites this paper
• eview ranscranial magnetic stimulation as a tool for understanding neurophysiology n Huntington ’ s disease : A review pril

  2013cites this paper
• Recent advances in imaging the onset and progression of Huntington’s disease

  2013cites this paper
• Functional and connectivity changes during working memory in Huntington's disease: 18 month longitudinal data from the IMAGE-HD study.

  2013cites this paper
• Basal ganglia function in genetic mouse models of Huntington's disease: a circuit-level approach

  2013cites this paper