Amprolium exposure alters mice behavior and metabolism in vivo

Thiamine deficiency (TD) models have been developed, mainly using the thiamine analog pyrithiamine. Other analogs have not been used in rodents. We aimed to evaluate the effects and mechanisms of intraperitoneal (ip) amprolium‐induced TD in mice. We also evaluated the associated pathogenesis using antioxidant and anti‐inflammatory compounds (Trolox, dimethyl sulfoxide).

• Publication year

  2018

• Venue

  Animal Models and Experimental Medicine

• Publication date

  2018-11-21

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1002/ame2.12040PMID 30891577PMCID 6388078
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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