Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting

Highlights • –1PRF occurs when ribosomes move over a slippery sequence.• A frameshifting pseudoknot/stem-loop element stalls ribosomes in a metastable state.• –1PRF may contribute to the quality-control machinery in eukaryotes.• Trans-acting factors (proteins, miRNAs, or antibiotics) can modulate –1PRF.

• Publication year

  2015

• Venue

  TIBS -Trends in Biochemical Sciences. Regular ed

• Publication date

  2015-04-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.tibs.2015.03.006PMID 25850333PMCID 7126180
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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