Bear Canyon Virus: An Arenavirus Naturally Associated with the California Mouse (Peromyscus californicus)

Thirty-four rodents captured in southern California were studied to increase our knowledge of the arenaviruses indigenous to the western United States. An infectious arenavirus was isolated from 5 of 27 California mice but none of the 7 other rodents. Analyses of viral nucleocapsid protein gene sequence data indicated that the isolates from the California mice are strains of a novel Tacaribe serocomplex virus (proposed name “Bear Canyon”) that is phylogenetically most closely related to Whitewater Arroyo and Tamiami viruses, the only other Tacaribe serocomplex viruses known to occur in North America. The discovery of Bear Canyon virus is the first unequivocal evidence that the virus family Arenaviridae is naturally associated with the rodent genus Peromyscus and that a Tacaribe serocomplex virus occurs in California.

• Publication year

  2002

• Venue

  Emerging Infectious Diseases

• Publication date

  2002-07-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.3201/eid0807.010281PMID 12095441PMCID 2730321
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PAUP*: Phylogenetic analysis using parsimony (*and other methods), Version 4.0b10

  2002cited by this paper
• Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.

  2001cited by this paper
• Arenaviridae: The viruses and their replication

  2001cited by this paper
• Experimental infection of Neotoma albigula (Muridae) with Whitewater Arroyo virus (Arenaviridae).

  2001cited by this paper
• Extreme genetic diversity among Pirital virus (Arenaviridae) isolates from western Venezuela.

  2001cited by this paper
• Arenavirus antibody in rodents indigenous to coastal southern California.

  2000influential reference
• Guanarito virus (Arenaviridae) isolates from endemic and outlying localities in Venezuela: sequence comparisons among and within strains isolated from Venezuelan hemorrhagic fever patients and rodents.

  2000cited by this paper
• Genetic Diversity among Lassa Virus Strains

  2000cited by this paper
• MODELTEST: testing the model of DNA substitution

  1998cited by this paper
• Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts.

  1997cited by this paper
• The phylogeny of New World (Tacaribe complex) arenaviruses.

  1996cited by this paper
• Isolation and characterization of Whitewater Arroyo virus, a novel North American arenavirus.

  1996cited by this paper
• Prevalence of antibodies to arenaviruses in rodents from the southern and western United States: evidence for an arenavirus associated with the genus Neotoma.

  1996cited by this paper
• Molecular phylogeny of Guanarito virus, an emerging arenavirus affecting humans.

  1995cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• Ecology and Epidemiology of Arenaviruses and Their Hosts

  1993cited by this paper
• CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP

  1985cited by this paper
• A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

  1980cited by this paper
• Tamiami virus, a new member of the TaCaribe group.

  1970cited by this paper
• Tamiami (TAM) strain. W-10777.

  1970cited by this paper
• Tamiami virus in the Tampa Bay area.

  1970cited by this paper

• Genetic characterization of the prion protein gene in camels (Camelus) with comments on the evolutionary history of prion disease in Cetartiodactyla

  2024cites this paper
• A Review of Mammarenaviruses and Rodent Reservoirs in the Americas

  2022cites this paper
• The Arenaviridae

  2020cites this paper
• A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover.

  2020cites this paper
• Species-level drivers of mammalian ectoparasite faunas.

  2020cites this paper
• REPTARENAVIRUSES IN CONSTRICTOR SNAKES: TISSUE TROPISM AND IMMUNE RESPONSES

  2020cites this paper
• Virus hébergés par les rongeurs en Guyane française.

  2017cites this paper
• Hemorrhagic Fever Viruses

  2016cites this paper
• Past, present, and future of arenavirus taxonomy

  2015cites this paper
• Gairo virus, a novel arenavirus of the widespread Mastomys natalensis: Genetically divergent, but ecologically similar to Lassa and Morogoro viruses.

  2015cites this paper
• Epizootiology of Tacaribe Serocomplex Viruses (Arenaviridae) Associated with Neotomine Rodents (Cricetidae, Neotominae) in Southern California

  2015cites this paper
• Human and Host Species Transferrin Receptor 1 Use by North American Arenaviruses

  2014cites this paper
• Arenavirus Variations Due to Host-Specific Adaptation

  2013cites this paper
• Ecology of Catarina Virus (family Arenaviridae) in Southern Texas, 2001–2004

  2013influential citation
• Complex patterns of host switching in New World arenaviruses

  2012cites this paper
• Diversity and phylogenetic relationships among the North American Tacaribe serocomplex viruses (family Arenaviridae).

  2011cites this paper
• Arenaviruses and Filoviruses

  2011cites this paper
• Genetic diversity in the transferrin receptor 1 (TfR1) among natural hosts of the North American arenaviruses

  2011influential citation
• The flexible C‐terminal arm of the Lassa arenavirus Z‐protein mediates interactions with multiple binding partners

  2010cites this paper
• Antibodies to Tacaribe Serocomplex Viruses (Family Arenaviridae, Genus Arenavirus) in Cricetid Rodents from New Mexico, Texas, and Mexico

  2010influential citation
• Genetic Evidence for a Tacaribe Serocomplex Virus, Mexico

  2010cites this paper
• Rodent-borne diseases and their risks for public health

  2009influential citation
• Receptor use by the Whitewater Arroyo virus glycoprotein.

  2008cites this paper
• Hantavirus and Arenavirus Antibodies in Persons with Occupational Rodent Exposure, North America

  2007cites this paper
• Toward a Molecular Phylogeny for Peromyscus: Evidence from Mitochondrial Cytochrome-b Sequences

  2007cites this paper
• Principal host relationships and evolutionary history of the North American arenaviruses.

  2007cites this paper
• Zoonoses and Other Human Health Hazards

  2007cites this paper
• Template for Taxonomic Proposal to the ICTV Executive Committee

  2007cites this paper
• Arenaviruses

  2007influential citation
• Tales of mice and men: Natural History of Arenaviruses

  2006cites this paper
• The Negative Sense Single Stranded RNA Viruses

  2005cites this paper
• History of U.S. military contributions to the study of viral hemorrhagic fevers.

  2005cites this paper
• The arenaviruses.

  2005cites this paper
• Phylogeny of the Venezuelan arenaviruses.

  2004cites this paper
• Generation of competent bone marrow-derived antigen presenting cells from the deer mouse (Peromyscus maniculatus)

  2004cites this paper
• Epizootiology of arenaviral infections in the white-throated woodrat (Muridae: Sigmodontinae) and other woodrats in Arizona.

  2004cites this paper
• The dynamics of two viral infections in a single host population with applications to hantavirus.

  2003cites this paper
• Phylogeny of New World arenaviruses based on the complete coding sequences of the small genomic segment identified an evolutionary lineage produced by intrasegmental recombination.

  2002cites this paper
• Viral hemorrhagic fevers of South America.

  2002influential citation