Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.

Xue-liang Du,D. Edelstein,L. Rossetti,I. Fantus,H. Goldberg,F. Ziyadeh,Jie Wu,M. Brownlee

Published 2000 in Proceedings of the National Academy of Sciences of the United States of America

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