The conversion of catechol and protocatechuate to beta-ketoadipate by Pseudomonas putida.

SUMMARY Two new intermediates were identified in the protocatechuate pathway of Pseudomonas putida. The first of these, y - carboxymuconolactone (y -carboxy- y-carboxymethyl- A-butenolide), is the product of the enzymic lactonization of #-carboxy-cis, cis-muconate. Enzymic decarboxylation of y-carboxymuconolactone gives rise to -ketoadipate enol-lactone (y-carboxymethyl-A 5 -butenolide), the second newly discovered intermediate in the protocatechuate pathway. -Ketoadipate enol-lactone, which was isolated and physi-cally characterized, is also an intermediate in the catechol pathway; the catechol and protocatechuate pathways con-verge at this point. -Ketoadipate enol-lactone is hydrolyzed to P-ketoadipate an enzyme for utilization of either catechol or also degrades protocatechuate and catechol by the pathways characteristic of P. putida.

• Publication year

  1966

• Venue

  Journal of Biological Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/s0021-9258(18)99839-xPMID 5916391
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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