Arabidopsis Basic Helix-Loop-Helix Transcription Factors MYC2, MYC3, and MYC4 Regulate Glucosinolate Biosynthesis, Insect Performance, and Feeding Behavior[W][OPEN]

A triple mutant of MYC2, MYC3, and MYC4 transcription factors is devoid of glucosinolates and more sensitive to attack by a generalist insect. These MYCs physically interact with six MYB transcription factors (MYB28, MYB29, MYB34, MYB51, MYB76, and MYB122) and regulate both basal and inducible glucosinolate levels by directly activating the expression of glucosinolate biosynthesis genes. Arabidopsis thaliana plants fend off insect attack by constitutive and inducible production of toxic metabolites, such as glucosinolates (GSs). A triple mutant lacking MYC2, MYC3, and MYC4, three basic helix-loop-helix transcription factors that are known to additively control jasmonate-related defense responses, was shown to have a highly reduced expression of GS biosynthesis genes. The myc2 myc3 myc4 (myc234) triple mutant was almost completely devoid of GS and was extremely susceptible to the generalist herbivore Spodoptera littoralis. On the contrary, the specialist Pieris brassicae was unaffected by the presence of GS and preferred to feed on wild-type plants. In addition, lack of GS in myc234 drastically modified S. littoralis feeding behavior. Surprisingly, the expression of MYB factors known to regulate GS biosynthesis genes was not altered in myc234, suggesting that MYC2/MYC3/MYC4 are necessary for direct transcriptional activation of GS biosynthesis genes. To support this, chromatin immunoprecipitation analysis showed that MYC2 binds directly to the promoter of several GS biosynthesis genes in vivo. Furthermore, yeast two-hybrid and pull-down experiments indicated that MYC2/MYC3/MYC4 interact directly with GS-related MYBs. This specific MYC–MYB interaction plays a crucial role in the regulation of defense secondary metabolite production and underlines the importance of GS in shaping plant interactions with adapted and nonadapted herbivores.

• Publication year

  2013

• Venue

  The Plant Cell

• Publication date

  2013-08-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1105/tpc.113.115139PMID 23943862PMCID PMC3784603
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MYC2: the master in action.

  2013cited by this paper
• Differential Contribution of Transcription Factors to Arabidopsis thaliana Defense Against Spodoptera littoralis

  2013cited by this paper
• TIME FOR COFFEE Represses Accumulation of the MYC2 Transcription Factor to Provide Time-of-Day Regulation of Jasmonate Signaling in Arabidopsis[C][W][OA]

  2012cited by this paper
• Fast gapped-read alignment with Bowtie 2

  2012cited by this paper
• Rapid profiling of intact glucosinolates in Arabidopsis leaves by UHPLC-QTOFMS using a charged surface hybrid column.

  2012cited by this paper
• Arabidopsis MYC2 Interacts with DELLA Proteins in Regulating Sesquiterpene Synthase Gene Expression[W][OA]

  2012cited by this paper
• NRT/PTR transporters are essential for translocation of glucosinolate defence compounds to seeds

  2012cited by this paper
• The Jasmonate-ZIM Domain Proteins Interact with the R2R3-MYB Transcription Factors MYB21 and MYB24 to Affect Jasmonate-Regulated Stamen Development in Arabidopsis[C][W]

  2011cited by this paper
• Characterization of JAZ-interacting bHLH transcription factors that regulate jasmonate responses in Arabidopsis

  2011cited by this paper
• Improved protein-binding microarrays for the identification of DNA-binding specificities of transcription factors.

  2011cited by this paper
• Evolutionary and comparative analysis of MYB and bHLH plant transcription factors.

  2011cited by this paper
• Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis

  2011cited by this paper
• The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis thaliana[C][W]

  2011cited by this paper
• FIMO: scanning for occurrences of a given motif

  2011cited by this paper
• The Arabidopsis bHLH Transcription Factors MYC3 and MYC4 Are Targets of JAZ Repressors and Act Additively with MYC2 in the Activation of Jasmonate Responses[C][W]

  2011cited by this paper
• DELLAs modulate jasmonate signaling via competitive binding to JAZs.

  2010influential reference
• Jasmonate perception by inositol phosphate-potentiated COI1-JAZ co-receptor

  2010cited by this paper
• EuroDia: a beta-cell gene expression resource

  2010cited by this paper
• NINJA connects the co-repressor TOPLESS to jasmonate signalling

  2010cited by this paper
• Biosynthesis of glucosinolates--gene discovery and beyond.

  2010influential reference
• Differential Effects of Indole and Aliphatic Glucosinolates on Lepidopteran Herbivores

  2010influential reference
• Genes of primary sulfate assimilation are part of the glucosinolate biosynthetic network in Arabidopsis thaliana.

  2010cited by this paper
• A Complex Interplay of Three R2R3 MYB Transcription Factors Determines the Profile of Aliphatic Glucosinolates in Arabidopsis1[C][W][OA]

  2010influential reference
• Non-Volatile Intact Indole Glucosinolates are Host Recognition Cues for Ovipositing Plutella xylostella

  2009cited by this paper
• (+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate.

  2009cited by this paper
• Origin and Diversification of Basic-Helix-Loop-Helix Proteins in Plants

  2009cited by this paper
• The ZIM domain mediates homo- and heteromeric interactions between Arabidopsis JAZ proteins.

  2009influential reference
• Jasmonate passes muster: a receptor and targets for the defense hormone.

  2009cited by this paper
• The Impact of the Absence of Aliphatic Glucosinolates on Insect Herbivory in Arabidopsis

  2008cited by this paper
• HAG2/MYB76 and HAG3/MYB29 exert a specific and coordinated control on the regulation of aliphatic glucosinolate biosynthesis in Arabidopsis thaliana.

  2008influential reference
• Plant immunity to insect herbivores.

  2008cited by this paper
• Comparative transcriptome analysis of Arabidopsis thaliana infested by diamond back moth (Plutella xylostella) larvae reveals signatures of stress response, secondary metabolism, and signalling

  2008cited by this paper
• Nonuniform distribution of glucosinolates in Arabidopsis thaliana leaves has important consequences for plant defense

  2008influential reference
• Indole-3-Acetonitrile Production from Indole Glucosinolates Deters Oviposition by Pieris rapae1[W][OA]

  2008cited by this paper
• COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine

  2008cited by this paper
• The glutathione-deficient mutant pad2-1 accumulates lower amounts of glucosinolates and is more susceptible to the insect herbivore Spodoptera littoralis.

  2008influential reference
• Model-based Analysis of ChIP-Seq (MACS)

  2008influential reference
• CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes

  2007cited by this paper
• The JAZ family of repressors is the missing link in jasmonate signalling

  2007influential reference
• MYC2 Differentially Modulates Diverse Jasmonate-Dependent Functions in Arabidopsis[W]

  2007cited by this paper
• Signaling pathways controlling induced resistance to insect herbivores in Arabidopsis.

  2007influential reference
• Co(i)-ordinating defenses: NaCOI1 mediates herbivore- induced resistance in Nicotiana attenuata and reveals the role of herbivore movement in avoiding defenses.

  2007cited by this paper
• The transcription factor HIG1/MYB51 regulates indolic glucosinolate biosynthesis in Arabidopsis thaliana.

  2007influential reference
• A Downstream Mediator in the Growth Repression Limb of the Jasmonate Pathway[W][OA]

  2007cited by this paper
• A Systems Biology Approach Identifies a R2R3 MYB Gene Subfamily with Distinct and Overlapping Functions in Regulation of Aliphatic Glucosinolates

  2007cited by this paper
• JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling

  2007cited by this paper
• Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis

  2007cited by this paper
• The R2R3-MYB transcription factor HAG1/MYB28 is a regulator of methionine-derived glucosinolate biosynthesis in Arabidopsis thaliana.

  2007influential reference
• Gene expression and glucosinolate accumulation in Arabidopsis thaliana in response to generalist and specialist herbivores of different feeding guilds and the role of defense signaling pathways.

  2006cited by this paper
• Arabidopsis myrosinases TGG1 and TGG2 have redundant function in glucosinolate breakdown and insect defense.

  2006cited by this paper
• Isothiocyanates Stimulating Oviposition by the Diamondback Moth, Plutella xylostella

  2006cited by this paper
• The enzymic and chemically induced decomposition of glucosinolates.

  2006cited by this paper
• The Arabidopsis ATR1 Myb Transcription Factor Controls Indolic Glucosinolate Homeostasis1

  2005cited by this paper
• The glucosinolate-myrosinase system in an ecological and evolutionary context.

  2005cited by this paper
• Signal signature and transcriptome changes of Arabidopsis during pathogen and insect attack.

  2005cited by this paper
• Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

  2004cited by this paper
• A Conserved Transcript Pattern in Response to a Specialist and a Generalist Herbivorew⃞

  2004influential reference
• Successful herbivore attack due to metabolic diversion of a plant chemical defense.

  2004cited by this paper
• The Tomato Homolog of CORONATINE-INSENSITIVE1 Is Required for the Maternal Control of Seed Maturation, Jasmonate-Signaled Defense Responses, and Glandular Trichome Development Online version contains Web-only data. Article, publication date, and citation information can be found at www.plantcell.org

  2004cited by this paper
• A Link between circadian-controlled bHLH factors and the APRR1/TOC1 quintet in Arabidopsis thaliana.

  2003cited by this paper
• Statistical significance for genomewide studies

  2003cited by this paper
• Modulation of CYP79 Genes and Glucosinolate Profiles in Arabidopsis by Defense Signaling Pathways1

  2003influential reference
• Glucosinolate research in the Arabidopsis era.

  2002cited by this paper
• Constitutive plant toxins and their role in defense against herbivores and pathogens.

  2002cited by this paper
• Rapid screening for improved solubility of small human proteins produced as fusion proteins in Escherichia coli

  2002cited by this paper
• Dependence of Heterochromatic Histone H3 Methylation Patterns on the Arabidopsis Gene DDM1

  2002cited by this paper
• The roles of nicotine and natural enemies in determining larval feeding site distributions of Manduca sexta L. and Manduca quinquemaculata (Haworth) on tobacco

  2002cited by this paper
• Genetic architecture of plastic methyl jasmonate responses in Arabidopsis thaliana.

  2002cited by this paper
• Disarming the mustard oil bomb

  2002cited by this paper
• Differential Gene Expression in Response to Mechanical Wounding and Insect Feeding in Arabidopsis

  2000cited by this paper
• COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility.

  1998cited by this paper
• Insect-plant biology

  1998cited by this paper

• Enzymatic innovations in Angelica pubescens reveal dual coumarin biosynthetic pathways driving metabolic diversification.

  2026cites this paper
• The effect of salicylic acid on the morpho-physio and yield traits of Brassica juncea and expression pattern of MYC gene family under drought stress

  2026cites this paper
• Vernalization attenuates age-dependent decline of glucosinolates in cabbage (Brassica oleracea ssp. capitata) through coordinated transcriptomic and metabolomic reprogramming.

  2026cites this paper
• TgMYC2-TgPAL module regulated by jasmonic acid mediates the dehiscence of Torreya grandis staminate strobilus

  2026cites this paper
• Role of SlJAIB14 in tomato defense against cotton bollworm (Helicoverpa armigera).

  2026cites this paper
• Regulatory mechanisms of amino acid metabolic pathways in Rhododendron chrysanthum Pall. Under UV-B stress.

  2026cites this paper
• Creating a new oilseed crop, pennycress, by combining key domestication traits using CRISPR genome editing

  2026cites this paper
• Genome-wide identification of MYC transcription factors in Chrysanthemum morifolium and CmMYC25 promotes petal anthocyanin accumulation

  2026cites this paper
• Deciphering Defense Mechanisms and Genetic Determinants of Insect Resistance in Brassica Species

  2026cites this paper
• Glucosinolate variation, heterosis, and prediction of hybrid performance from parental values in white cabbage (Brassica oleracea var. capitata).

  2026cites this paper
• Impacts of Sulfur on Glucosinolate Metabolism: From Arabidopsis to Wild Brassicales

  2025cites this paper
• Research Advances and Perspectives on Early Flowering Traits in Cucumber

  2025cites this paper
• Transcriptional activation of BolBCAT4 genes enhanced aliphatic glucosinolate accumulation in cabbage

  2025cites this paper
• Global landscape of protein phosphorylation during plant regeneration initiation in cotton (Gossypium hirsutum L.)

  2025cites this paper
• A plant-specific cytochrome b5-like protein is essential for phytosterol biosynthesis.

  2025cites this paper
• Ectropis obliqua-Induced Secondary Metabolites Are Regulated by Methyl Jasmonate in a Threshold-Dependent Manner

  2025cites this paper
• Warm temperature and mild drought remodel transcriptome and alter Arabidopsis responses to mite herbivory

  2025cites this paper
• Arabidopsis MYB47 and MYB95 transcription factors regulate jasmonate-inducible ER-body formation

  2025influential citation
• Molecular interactions between plants and arthropod herbivores in the context of climate change.

  2025cites this paper
• Jasmonate and salicylate signaling in rice defense against brown planthopper nymphs.

  2025cites this paper
• MYC2a/b-regulated protease inhibitors in defense against Spodoptera litura in Nicotiana attenuata

  2025cites this paper
• Knocking out artificially selected gene GmAOC4H8 improves germination in soybean

  2025cites this paper
• Transcriptomic and Metabolomic Analyses Reveal Differing Phytohormone Regulation in Rhododendron Cultivars in Response to Azalea Lace Bug (Stephanitis pyrioides)

  2025cites this paper
• Genome-wide insights into the nomenclature, evolution and expression of tobacco TIFY/JAZ genes

  2025cites this paper
• ABC1K2 is involved in stress response and secondary metabolism during seed development in Arabidopsis thaliana

  2025cites this paper
• Enhanced accumulation of indole glucosinolate and resistance to insect and pathogen in flowering Chinese cabbage by overexpression of Arabidopsis CYP79B2 and CYP83B1

  2025cites this paper
• Deciphering the heterogeneous glucosinolates composition in leaves and seeds: strategies for developing Brassica napus genotypes with low seed glucosinolates content but high leaf glucosinolates content

  2025cites this paper
• A plant virus manipulates both its host plant and the insect that facilitates its transmission

  2025cites this paper
• Recent advances in the chemistry and biology of plant oxylipin hormones.

  2025cites this paper
• Nitrate reductase BoNIA2b responds to nitric oxide to positively regulate the accumulation of Glucoraphanin and Sulforaphane in broccoli hairy roots.

  2025cites this paper
• Control of Chloroplast Integrity by the Jasmonate Signaling Pathway is Linked to Growth-Defense Balance

  2025cites this paper
• ICE1 (Inducer of CBF Expression 1) Is Essential for the Jasmonate-Regulated Development of Stamen in Arabidopsis thaliana.

  2025cites this paper
• The MYC2-JAMYB transcriptional cascade regulates rice resistance to brown planthoppers.

  2025cites this paper
• Jasmonate signaling coordinates with the SOD7-KLU pathway to regulate seed size in Arabidopsis thaliana.

  2025cites this paper
• A natural variant of an MYC2 gene in soybean contributes to resistance against the common cutworm

  2025cites this paper
• Novel Regulators and Their Epistatic Networks in Arabidopsis' Defence Responses to Alternaria alternata Infection

  2025cites this paper
• The transcription factor BoMYC2 negatively regulates seed size by activating cytokinin dehydrogenase BoCKX5 in Broccoli

  2025cites this paper
• Deciphering the role of metabolites and phytohormones in plant resilience to drought and herbivory

  2025cites this paper
• Insect Production and Secretion of Phytohormones and Impacts on Host Plants.

  2025cites this paper
• CRISPR/Cas9-mediated mutation of GhCAD decreases the gossypol content of cottonseed

  2025cites this paper
• Flower jasmonates control fertility but largely disconnect from defense metabolites in reproductive tissues of rice (Oryza sativa L.).

  2025cites this paper
• Epigenetic Regulation of Glucosinolate Biosynthesis: Mechanistic Insights and Breeding Prospects in Brassicaceae

  2025cites this paper
• Modulating Fatty Acid Metabolism to Counteract Cucumber Green Mottle Mosaic Virus Infection in Cucumber.

  2025cites this paper
• A jasmonate‐mediated MAPK cascade regulates rice structural defense against brown planthoppers

  2025cites this paper
• Transcriptome and small RNA sequencings reveal the response of tobacco to aphid infestation

  2025cites this paper
• Salvia miltiorrhiza-derived carbon dots confer resistance to Sclerotinia sclerotiorum in Brassica napus L

  2025cites this paper
• The Roles of MYC2 Transcription Factor in JA-Signaling Pathway in Plants

  2025cites this paper
• BolANT3 Positively Regulates Indolic Glucosinolate Accumulation by Transcriptionally Activating BolCYP83B1 in Cabbage

  2025cites this paper
• Low concentration of sodium chloride combined with melatonin improved the nutritional quality of Chinese kale sprouts

  2025cites this paper
• Impact of Lepidopteran Oral Secretions on the Transcriptome of Arabidopsis thaliana

  2025cites this paper
• A transcription factor module mediating C2 photosynthesis in the Brassicaceae

  2025cites this paper
• Genome-wide identification, expression analysis of the MYC gene family in Stevia rebaudiana and the functional identification of SrMYC8 in SGs biosynthesis

  2025cites this paper
• Integration of transcriptome and phytohormone analyses reveals antagonistic interactions between jasmonate and auxin signaling pathways in rice (Oryza sativa L.)

  2025cites this paper
• Unveiling the basis of metabolite accumulation and stress adaptation in Chinese kale: Metabolic divergence and environmental regulation of glucosinolates and anthocyanins.

  2025cites this paper
• Regulatory mechanisms of ER body formation and its function in Brassicaceae plants.

  2025cites this paper
• Jasmonate signaling: integrating stress responses with developmental regulation in plants.

  2025cites this paper
• Marchantia polymorpha Defense Against Snail Herbivory

  2025cites this paper
• A Review of Transcriptomics and Metabolomics in Plant Quality and Environmental Response: From Bibliometric Analysis to Science Mapping and Future Trends

  2024cites this paper
• The SmMYC2-SmMYB36 complex is involved in methyl jasmonate-mediated tanshinones biosynthesis in Salvia miltiorrhiza.

  2024cites this paper
• Defense strategies and associated phytohormonal regulation in Brassica plants in response to chewing and sap-sucking insects

  2024cites this paper
• Salicylic acid positively regulates maize defenses against lepidopteran insects

  2024cites this paper
• Harnessing Phytohormones: Advancing Plant Growth and Defence Strategies for Sustainable Agriculture.

  2024cites this paper
• Enzyme-mediated adaptation of herbivorous insects to host phytochemicals

  2024cites this paper
• Genome-wide identification of the walnut MYC gene family and functional characterization of Xinjiang wild walnut under low-temperature stress

  2024cites this paper
• Rice responds to Spodoptera frugiperda infestation via epigenetic regulation of H3K9ac in the jasmonic acid signaling and phenylpropanoid biosynthesis pathways

  2024cites this paper
• Populus MYC2 orchestrates root transcriptional reprogramming of defence pathway to impair Laccaria bicolor ectomycorrhizal development.

  2024cites this paper
• Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis.

  2024cites this paper
• The MYC2-PUB22-JAZ4 module plays a crucial role in jasmonate signaling in tomato.

  2024cites this paper
• Chromosome-scale reference genome of broccoli (Brassica oleracea var. italica Plenck) provides insights into glucosinolate biosynthesis

  2024cites this paper
• Decreased cadmium content in Solanum melongena induced by grafting was related to glucosinolates synthesis.

  2024cites this paper
• Integrated transcriptome sequencing and iTRAQ quantitative proteomics analysis reveal the roles of PpJAZ1 and PpMYC2-2 in sand pear black spot disease resistance

  2024cites this paper
• SlCYP94B18 and SlCYP94B19 monooxygenases for the catabolic turnover of jasmonates in tomato leaves.

  2024cites this paper
• Transcriptome analysis reveals the potential mechanism of the response to scale insects in Camellia sasanqua Thunb

  2024cites this paper
• Transcriptome and metabolome analyses reveal the regulation effect of ultraviolet-B irradiation on secondary metabolites in pakchoi

  2024cites this paper
• Combined miRNA and mRNA sequencing reveals the defensive strategies of resistant YHY15 rice against differentially virulent brown planthoppers

  2024cites this paper
• The AMS/DYT1-MYB module interacts with the MED25-MYC-MYB complexes to inhibit jasmonate-regulated floral defense in Arabidopsis.

  2024cites this paper
• Advanced Nanostrategies for Biomolecule Delivery in Plant Disease Management.

  2024cites this paper
• Integrated analysis of miRNA-mRNA regulatory networks in Anoectochilus roxburghii in response to blue laser light.

  2024cites this paper
• A frameshift mutation in JAZ10 resolves the growth versus defense dilemma in rice

  2024cites this paper
• bHLH19 and bHLH20 repress jasmonate-mediated plant defense against insect herbivores in Arabidopsis.

  2024cites this paper
• MYB transcription factors in plants: A comprehensive review of their discovery, structure, classification, functional diversity and regulatory mechanism.

  2024cites this paper
• Different multicellular trichome types coordinate herbivore mechanosensing and defense in tomato.

  2024cites this paper
• Comprehensive Transcriptomic Analysis Reveals Defense-Related Genes and Pathways of Rice Plants in Response to Fall Armyworm (Spodoptera frugiperda) Infestation

  2024cites this paper
• Jasmonate-mediated polyamine oxidase 6 drives herbivore-induced polyamine catabolism in rice.

  2024cites this paper
• Jasmonate induces translation of the Arabidopsis tRNA-binding protein YUELAO1, which activates MYC2 in jasmonate signaling.

  2024cites this paper
• Evolution of thaumatin-like proteins in rosaceae and rapid response to cold stimulation coordinated with PmEOBⅡ in the floral scent formation process of Prunus mume

  2024cites this paper
• From trade-off to synergy: how nutrient status modulates plant resistance to herbivorous insects?

  2024cites this paper
• Advances in functional studies of plant MYC transcription factors

  2024cites this paper
• Chickpea defense against dual stresses of salt and Fusarium wilt is enhanced through selected bHLH transcription factors carrying the bHLH-MYC_N domain.

  2024cites this paper
• Evolution and comparative transcriptome analysis of glucosinolate pathway genes in Brassica napus L.

  2024cites this paper
• AaMYC3 bridges the regulation of glandular trichome density and artemisinin biosynthesis in Artemisia annua

  2024cites this paper
• Expression Pattern and Functional Analysis of MebHLH149 Gene in Response to Cassava Bacterial Blight

  2024cites this paper
• Arabidopsis thaliana MYC2 and MYC3 Are Involved in Ethylene-Regulated Hypocotyl Growth as Negative Regulators

  2024cites this paper
• The Arabidopsis ARID-HMG DNA-BINDING PROTEIN 15 modulates JA signaling by regulating MYC2 during pollen development.

  2024cites this paper
• A structure-redesigned intrinsically disordered peptide that selectively inhibits a plant transcription factor in jasmonate signaling

  2024cites this paper
• Differential induction of JA/SA determines plant defense against successive leaf-chewing and phloem-feeding insects

  2024cites this paper
• Metabolites-induced co-evolutionary warfare between plants, viruses, and their associated vectors: So close yet so far away.

  2024cites this paper
• Transcriptomic and coexpression network analyses revealed the regulatory mechanism of Cydia pomonella infestation on the synthesis of phytohormones in walnut husks

  2024cites this paper
• Transcription factor ABF3 modulates salinity stress-enhanced jasmonate signaling in Arabidopsis

  2024cites this paper
• CRISPR/Cas9-mediated knockout of NtMYC2a gene involved in resistance to bacterial wilt in tobacco.

  2024cites this paper