Cytokines and antibodies in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Research in Immunology

• Publication date

  1998-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0923-2494(99)80007-8PMID 9923635
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions

  2004cited by this paper
• Tumor Necrosis Factor (cid:2) and Lymphotoxin (cid:2) Are Not Required for Induction of Acute Experimental Autoimmune Encephalomyelitis

  2002cited by this paper
• Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis

  1998cited by this paper
• Acute and relapsing experimental autoimmune encephalomyelitis in IL-4- and alpha/beta T cell-deficient C57BL/6 mice.

  1998cited by this paper
• B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization.

  1998cited by this paper
• IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein.

  1998cited by this paper
• A Molecular Model of Myelin Oligodendrocyte Glycoprotein

  1998cited by this paper
• B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice

  1998cited by this paper
• TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination

  1998cited by this paper
• Challenging Cytokine Redundancy: Inflammatory Cell Movement and Clinical Course of Experimental Autoimmune Encephalomyelitis Are Normal in Lymphotoxin-deficient, but Not Tumor Necrosis Factor–deficient, Mice

  1998cited by this paper
• IL‐6‐deficient mice resist myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis

  1998cited by this paper
• The effect of B cell deficiency on the immune response to acetylcholine receptor and the development of experimental autoimmune myasthenia gravis.

  1998cited by this paper
• The Development of Autoimmune Encephalomyelitis Provoked by Myelin Oligodendrocyte Glycoprotein Is Associated with an Upregulation of Both Proinflammatory and Immunoregulatory Cytokines in the Central Nervous System

  1998cited by this paper
• Acute and relapsing experimental autoimmune encephalomyelitis in IL-4- and α/β T cell-deficient C57BL/6 mice

  1998cited by this paper
• A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice.

  1998cited by this paper
• Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein‐induced experimental autoimmune encephalomyelitis and antibody isotype pattern

  1998cited by this paper
• Interleukin‐6 functions in autoimmune encephalomyelitis: a study in gene‐targeted mice

  1998cited by this paper
• Binding of complement component C1q to myelin oligodendrocyte glycoprotein: A novel mechanism for regulating CNS inflammation

  1998cited by this paper
• Binding of complement component Clq to myelin oligodendrocyte glycoprotein: A novel mechanism for regulating CNS inflammation

  1997cited by this paper
• Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

  1997cited by this paper
• Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

  1997cited by this paper
• Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting

  1997cited by this paper
• A Critical Role for Lymphotoxin in Experimental Allergic Encephalomyelitis

  1997cited by this paper
• Experimental autoimmune encephalomyelitis in IL-4-deficient mice.

  1997cited by this paper
• Interferon γ (IFN-γ) Is Necessary for the Genesis of Acetylcholine Receptor–induced Clinical Experimental Autoimmune Myasthenia gravis in Mice

  1997cited by this paper
• Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis

  1997cited by this paper
• IL-6: insights into novel biological activities.

  1997cited by this paper
• Differential regulation of chemokines by leukemia inhibitory factor, interleukin-6 and oncostatin M.

  1997cited by this paper
• Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor‐α in the central nervous system

  1997cited by this paper
• Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

  1997cited by this paper
• Myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas‐ and Fas ligand‐deficient lpr and gld mice

  1997cited by this paper
• Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.

  1997cited by this paper
• Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice.

  1997cited by this paper
• Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

  1997cited by this paper
• Interferon‐γ confers resistance to experimental allergic encephalomyelitis

  1996cited by this paper
• Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

  1996cited by this paper
• IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.

  1996cited by this paper
• Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice.

  1996cited by this paper
• Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55.

  1996cited by this paper
• Late Complications of Immune Deviation Therapy in a Nonhuman Primate

  1996cited by this paper
• Production of Monocyte Chemotactic Protein‐1 By Rat Brain Macrophages

  1996cited by this paper
• Chronic inflammation caused by lymphotoxin is lymphoid neogenesis

  1996cited by this paper
• Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

  1996cited by this paper
• Inheritance of susceptibility to experimental autoimmune encephalomyelitis

  1996cited by this paper
• Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha.

  1995cited by this paper
• Transcriptional activation by tetracyclines in mammalian cells.

  1995cited by this paper
• A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H‐2b mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells

  1995cited by this paper
• IL‐6 Expression in Neurons of Transgenic Mice Causes Reactive Astrocytosis and Increase in Ramified Microglial Cells but no Neuronal Damage

  1995cited by this paper
• Neuropathogenic actions of cytokines assessed in transgenic mice

  1995cited by this paper
• Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.

  1995cited by this paper
• Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia

  1994cited by this paper
• Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice.

  1994cited by this paper
• Regulation of an oligodendrocyte progenitor cell line by the interleukin‐6 family of cytokines

  1994cited by this paper
• Monoclonal autoantibodies promote central nervous system repair in an animal model of multiple sclerosis

  1994cited by this paper
• Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin.

  1994cited by this paper
• Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis.

  1994cited by this paper
• Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

  1993cited by this paper
• Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

  1993cited by this paper
• The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

  1993cited by this paper
• Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor.

  1993cited by this paper
• Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis.

  1993cited by this paper
• Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily

  1992cited by this paper
• Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody.

  1992cited by this paper
• Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis.

  1992cited by this paper
• Effect of anti-interferon-γ and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse

  1992cited by this paper
• A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

  1991cited by this paper
• Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.

  1991cited by this paper
• Antibodies to myelin-oligodendrocyte glycoprotein in cerebrospinal fluid from patients with multiple sclerosis and controls.

  1991cited by this paper
• T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis.

  1991cited by this paper
• Anti—tumor necrosis factor therapy abrogates autoimmune demyelination

  1991cited by this paper
• Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity.

  1990cited by this paper
• Demyelination Induced in Aggregating Brain Cell Cultures by a Monoclonal Antibody Against Myelin/Oligodendrocyte Glycoprotein

  1990cited by this paper
• An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

  1990cited by this paper
• Differential Ultrastructural Localization of Myelin Basic Protein, Myelin/Oligodendroglial Glycoprotein, and 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase in the CNS of Adult Rats

  1989cited by this paper
• The role of complement in the pathogenesis of experimental allergic encephalomyelitis.

  1989cited by this paper
• Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.

  1989cited by this paper
• Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.

  1988cited by this paper
• Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG).

  1987cited by this paper
• A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease.

  1987cited by this paper
• Immunoglobulin-deficient rats fail to develop experimental allergic encephalomyelitis.

  1983cited by this paper
• Intact B-cell activity is essential for complete expression of experimental allergic encephalomyelitis in Lewis rats.

  1982cited by this paper
• CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY

  1968cited by this paper

• Chronic experimental autoimmune encephalomyelitis is an excellent model to study neuroaxonal degeneration in multiple sclerosis

  2022cites this paper
• Pharmacotherapy with 17β-estradiol and progesterone prevents development of mouse experimental autoimmune encephalomyelitis

  2010cites this paper
• Chemokine receptor expression and function in experimental autoimmune neuroinflammation

  2007cites this paper
• Multiple sclerosis: a battle between destruction and repair

  2007cites this paper
• EXPRESSION AND FUNCTION IN EXPERIMENTAL AUTOIMMUNE NEUROINFLAMMATION

  2007cites this paper
• Astroglial‐derived lymphotoxin‐α exacerbates inflammation and demyelination, but not remyelination

  2005cites this paper
• Schistosomiasis protects against multiple sclerosis.

  2004cites this paper
• Schistosomiasis Decreases Central Nervous System Inflammation and Alters the Progression of Experimental Autoimmune Encephalomyelitis

  2003cites this paper
• The EAE-associated behavioral syndrome: I. Temporal correlation with inflammatory mediators.

  2003cites this paper
• The EAE-associated behavioral syndrome: II. Modulation by anti-inflammatory treatments.

  2003cites this paper
• Genetic models for CNS inflammation

  2001cites this paper
• Tumor necrosis factor: a master-regulator of leukocyte movement.

  2000cites this paper
• Inflammatory Processes:

  2000cites this paper
• Kinetics and Cellular Origin of Cytokines in the Central Nervous System: Insight into Mechanisms of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis1

  2000cites this paper
• Autoimmune Encephalomyelitis Glycoprotein-Induced Experimental Mechanisms of Myelin Oligodendrocyte the Central Nervous System : Insight into Kinetics and Cellular Origin of Cytokines in

  1999cites this paper
• Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.

  1999cites this paper
• Experimental Allergic Encephalomyelitis of the Complement Inhibitor sCrry Prevents Central Nervous System-Targeted Expression

  1999cites this paper