A crystal structure reveals an elegant mechanistic switch whereby helical bending and catalytic domain rotation allow self-activation of a histidine kinase during a bacterial stress response.
Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains
Chen Wang,J. Sang,Jiawei Wang,Mingyan Su,J. S. Downey,Qinggan Wu,Shida Wang,Yongfei Cai,Xiaozheng Xu,Jun Wu,D. Senadheera,D. Cvitkovitch,Lin Chen,S. Goodman,A. Han
Published 2013 in PLoS Biology
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PUBLICATION RECORD
- Publication year
2013
- Venue
PLoS Biology
- Publication date
2013-02-01
- Fields of study
Biology, Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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