BAFF-driven autoimmunity requires CD19 expression.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Autoimmunity

• Publication date

  2015-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.jaut.2015.06.001PMID 26103922
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CD19 differentially regulates BCR signalling through the recruitment of PI3K

  2014cited by this paper
• The BAFF/APRIL system in SLE pathogenesis

  2014cited by this paper
• The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

  2013cited by this paper
• Interleukin-6 trans-signaling exacerbates inflammation and renal pathology in lupus-prone mice.

  2013cited by this paper
• Context-specific BAFF-R signaling by the NF-κB and PI3K pathways.

  2013cited by this paper
• FcγRIIb and BAFF Differentially Regulate Peritoneal B1 Cell Survival

  2012cited by this paper
• BAFF/BLyS inhibitors: A new prospect for treatment of systemic lupus erythematosus

  2012cited by this paper
• Genetic Interdependence of Lyn and Negative Regulators of B Cell Receptor Signaling in Autoimmune Disease Development

  2012cited by this paper
• The Capsular Polysaccharide Vi from Salmonella Typhi Is a B1b Antigen

  2012cited by this paper
• Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice.

  2011cited by this paper
• The SLAM family member CD48 (Slamf2) protects lupus-prone mice from autoimmune nephritis.

  2011cited by this paper
• Signaling Pathways in T Follicular Helper Cells

  2010cited by this paper
• CD22 × Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity

  2010cited by this paper
• This information is current as Signaling Transitional B Cells following Tonic BCR Differentiation of Immature B Cells into BAFF Receptor Signaling Aids the

  2010cited by this paper
• Signalling crosstalk in B cells: managing worth and need

  2009cited by this paper
• High Sensitive Detection of Double‐Stranded DNA Autoantibodies by a Modified Crithidia luciliae Immunofluorescence Test

  2009cited by this paper
• From the fetal liver to spleen and gut: the highway to natural antibody

  2009cited by this paper
• Plasma cell development: from B-cell subsets to long-term survival niches.

  2008cited by this paper
• B‐cell responses to B‐cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta

  2008cited by this paper
• Different Kinetics of Blimp-1 Induction in B Cell Subsets Revealed by Reporter Gene1

  2007cited by this paper
• BAFF and MyD88 signals promote a lupuslike disease independent of T cells

  2007cited by this paper
• B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

  2007cited by this paper
• Siglec-G is a B1 cell–inhibitory receptor that controls expansion and calcium signaling of the B1 cell population

  2007cited by this paper
• Development of autoimmunity in IL-14alpha-transgenic mice.

  2006cited by this paper
• BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanism

  2006cited by this paper
• Identification of a B-1 B cell–specified progenitor

  2006cited by this paper
• Development of nephritis but not sialadenitis in autoimmune‐prone BAFF transgenic mice lacking marginal zone B cells

  2006cited by this paper
• Rap1 signal controls B cell receptor repertoire and generation of self-reactive B1a cells.

  2006cited by this paper
• Development of Autoimmunity in IL-14α-Transgenic Mice1

  2006cited by this paper
• B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae.

  2005cited by this paper
• A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

  2005cited by this paper
• B1b lymphocytes confer T cell-independent long-lasting immunity.

  2004cited by this paper
• Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression

  2004cited by this paper
• Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

  2004cited by this paper
• CD19 Function in Early and Late B Cell Development: I. Maintenance of Follicular and Marginal Zone B Cells Requires CD19-Dependent Survival Signals1

  2003cited by this paper
• Expansion of marginal zone B cells is not sufficient for the development of renal disease in NZB×NZW F1 mice

  2002cited by this paper
• CD19-dependent Activation of Akt Kinase in B-lymphocytes*

  2001cited by this paper
• B cell development pathways.

  2001cited by this paper
• B1 cells: similarities and differences with other B cell subsets.

  2001cited by this paper
• Maturation of Marginal Zone and Follicular B Cells Requires B Cell Activating Factor of the Tumor Necrosis Factor Family and Is Independent of B Cell Maturation Antigen

  2001cited by this paper
• Baff Mediates Survival of Peripheral Immature B Lymphocytes

  2000cited by this paper
• Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

  2000cited by this paper
• B‐1 cells: the lineage question revisited

  2000cited by this paper
• CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation.

  1999cited by this paper
• Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

  1999cited by this paper
• Antiviral Protection and Germinal Center Formation, But Impaired B Cell Memory in the Absence of CD19

  1998cited by this paper
• Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice.

  1997cited by this paper
• Defective B cell development and function in Btk-deficient mice.

  1995cited by this paper
• The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation.

  1995cited by this paper
• Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

  1995cited by this paper
• Impairment of T-cell-dependent B-cell responses and B-l cell development in CD19-deficient mice

  1995cited by this paper
• CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.

  1992cited by this paper
• Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.

  1989cited by this paper
• The effect of thymectomy on lupus-prone mice.

  1984cited by this paper
• The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice

  1983cited by this paper
• ROLE OF GAMMA GLOBULINS IN PATHOGENESIS OF RENAL LESIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND CHRONIC MEMBRANOUS GLOMERULONEPHRITIS, WITH AN OBSERVATION ON THE LUPUS ERYTHEMATOSUS CELL REACTION

  1957cited by this paper

• Intracellular Flow Cytometry ("Phosphoflow") to Assess Signal Transduction in Rare Populations Such As Memory B Cell Subsets and Plasma Cells.

  2024cites this paper
• B Cell Tolerance and Targeted Therapies in SLE

  2023cites this paper
• A quinazoline derivative suppresses B cell hyper-activation and ameliorates the severity of systemic lupus erythematosus in mice

  2023cites this paper
• Aberrant B-Cell Activation in Systemic Lupus Erythematosus

  2022cites this paper
• TGF-β1 Signaling: Immune Dynamics of Chronic Kidney Diseases

  2021cites this paper
• Hallmark of Systemic Lupus Erythematosus: Role of B Cell Hyperactivity

  2021cites this paper
• Homeostasis and regulation of autoreactive B cells

  2020cites this paper
• BST-2/Tetherin is involved in BAFF-enhanced proliferation and survival via canonical NF-κB signaling in neoplastic B-lymphoid cells.

  2020cites this paper
• Overview of anti‐BCMA CAR‐T immunotherapy for multiple myeloma and relapsed/refractory multiple myeloma

  2020cites this paper
• Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease

  2020cites this paper
• Efficacy and safety of iguratimod plus corticosteroid as bridge therapy in treating mild IgG4‐related diseases: A prospective clinical trial

  2019cites this paper
• BAFF inhibits autophagy promoting cell proliferation and survival by activating Ca2+-CaMKII-dependent Akt/mTOR signaling pathway in normal and neoplastic B-lymphoid cells.

  2019cites this paper
• Animal Models in Lupus

  2019cites this paper
• Editor’s Pick: Systemic Sclerosis: The Role of YAP/TAZ in Disease Pathogenesis

  2019cites this paper
• BAFF inhibition in SLE—Is tolerance restored?

  2019cites this paper
• Systemic Sclerosis : The Role of YAP / TAZ in Disease Pathogenesis

  2019cites this paper
• Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.

  2018cites this paper
• Belimumab promotes negative selection of activated autoreactive B cells in systemic lupus erythematosus patients.

  2018cites this paper
• Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells

  2018cites this paper
• The long and the short of it: insights into the cellular source of autoantibodies as revealed by B cell depletion therapy.

  2018cites this paper
• Development of specific nanobodies (VHH) for CD19 immuno-targeting of human B-lymphocytes

  2018cites this paper
• Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity

  2017cites this paper
• CD19, from bench to bedside.

  2017cites this paper
• A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia.

  2017cites this paper
• Defective Suppressor of Cytokine Signaling 1 Signaling Contributes to the Pathogenesis of Systemic Lupus Erythematosus

  2017cites this paper
• The Geoepidemiology and Clinical Aspects of IgG4-Related Disease

  2016cites this paper
• A Review of Clinical Trials of Belimumab in the Management of Systemic Lupus Erythematosus.

  2016cites this paper
• Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells

  2016cites this paper
• This information is current as of Transitional B Cells Production via TACI-Dependent Activation Cutting Edge : BAFF Promotes Autoantibody

  2016cites this paper
• Blood and salivary-gland BAFF-driven B-cell hyperactivity is associated to rituximab inefficacy in primary Sjögren's syndrome.

  2016cites this paper
• Serum BAFF and peripheral blood CD19+ B-lymphocytes in generalized vitiligo and relation to disease activity

  2016cites this paper
• BCR and co-receptor crosstalk facilitate the positive selection of self-reactive transitional B cells.

  2015influential citation