BACKGROUND Despite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysm subarachnoid haemorrhage (aSAH). OBJECTIVE To define the scope of the problem and review key treatment strategies that have shaped the way cerebral vasospasm is managed in the contemporary era. METHODS A literature search of cerebral vasospasm management after aneurysmal subarachnoid haemorrhage was performed. RESULTS Recent advances in neuroimaging have led to an improved detection of vasospasm, but established treatment guidelines including haemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centres. Experimental research in SAH continues to identify novel targets for therapy. CONCLUSIONS Proactive and preventative strategies such as oral nimodipine and endovascular rescue therapies can reduce the morbidity and mortality associated with CV.
A review on the management of cerebral vasospasm following aneurysmal subarachnoid haemorrhage.
Kenny Li,C. Barras,R. Chandra,H. Kok,J. Maingard,N. Carter,Jeremy Russell,L. Lai,M. Brooks,H. Asadi
Published 2019 in World Neurosurgery
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
World Neurosurgery
- Publication date
2019-06-01
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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