Advances in mRNA Vaccines for Infectious Diseases

Cuiling Zhang,Giulietta Maruggi,H. Shan,Junwei Li

Published 2019 in Frontiers in Immunology

ABSTRACT

During the last two decades, there has been broad interest in RNA-based technologies for the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have shown that mRNA vaccines provide a safe and long-lasting immune response in animal models and humans. In this review, we summarize current research progress on mRNA vaccines, which have the potential to be quick-manufactured and to become powerful tools against infectious disease and we highlight the bright future of their design and applications.

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