One of the principles underpinning our understanding of ageing is that DNA damage induces a stress response that shifts cellular resources from growth towards maintenance. A contrasting and seemingly irreconcilable view is that prompting growth of, for example, skeletal muscle confers systemic benefit.
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling
Khalid Alyodawi,W. Vermeij,S. Omairi,O. Kretz,M. Hopkinson,Francesca Solagna,Barbara Joch,Renata M. C. Brandt,S. Barnhoorn,Nicole van Vliet,Y. Ridwan,J. Essers,R. Mitchell,Taryn Morash,A. Pasternack,O. Ritvos,A. Matsakas,H. Collins‐Hooper,T. Huber,J. Hoeijmakers,K. Patel
Published 2019 in Journal of Cachexia, Sarcopenia and Muscle
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
Journal of Cachexia, Sarcopenia and Muscle
- Publication date
2019-03-27
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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