The COP9 Signalosome: Its Regulation of Cullin-Based E3 Ubiquitin Ligases and Role in Photomorphogenesis1

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Plant Physiology

• Publication date

  2012-06-19

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1104/pp.112.198879PMID 22715109PMCID PMC3440213
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Department of Biology

  2019cited by this paper
• The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6

  2012cited by this paper
• Neurospora COP9 Signalosome Integrity Plays Major Roles for Hyphal Growth, Conidial Development, and Circadian Function

  2012cited by this paper
• Structural basis of ultraviolet-B perception by UVR8

  2012cited by this paper
• Genomic basis for light control of plant development

  2012cited by this paper
• The photomorphogenic repressors COP1 and DET1: 20 years later.

  2012cited by this paper
• WD40 and CUL4-based E3 ligases: lubricating all aspects of life.

  2011cited by this paper
• Interaction of Arabidopsis DET1 with CCA1 and LHY in mediating transcriptional repression in the plant circadian clock.

  2011cited by this paper
• COP9 signalosome subunit 7 from Arabidopsis interacts with and regulates the small subunit of ribonucleotide reductase (RNR2)

  2011cited by this paper
• The cullin-RING ubiquitin-protein ligases.

  2011cited by this paper
• Photobodies in Light Signaling1

  2011cited by this paper
• Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.

  2011cited by this paper
• Ubiquitin ligase switch in plant photomorphogenesis: A hypothesis

  2011cited by this paper
• Phylogenetic Comparison of F-Box (FBX) Gene Superfamily within the Plant Kingdom Reveals Divergent Evolutionary Histories Indicative of Genomic Drift

  2011cited by this paper
• Perception of UV-B by the Arabidopsis UVR8 Protein

  2011cited by this paper
• COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ

  2011cited by this paper
• The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.

  2011cited by this paper
• The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

  2011influential reference
• Negative feedback regulation of UV-B–induced photomorphogenesis and stress acclimation in Arabidopsis

  2010cited by this paper
• Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.

  2010cited by this paper
• Arabidopsis PHYTOCHROME INTERACTING FACTOR Proteins Promote Phytochrome B Polyubiquitination by COP1 E3 Ligase in the Nucleus[C][W]

  2010cited by this paper
• Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.

  2010influential reference
• Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution

  2010cited by this paper
• Fungal development and the COP9 signalosome.

  2010cited by this paper
• Arabidopsis CULLIN4-Damaged DNA Binding Protein 1 Interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA Complexes to Regulate Photomorphogenesis and Flowering Time[C][W]

  2010cited by this paper
• SPA1 and DET1 act together to control photomorphogenesis throughout plant development

  2010cited by this paper
• Interaction of COP1 and UVR8 regulates UV‐B‐induced photomorphogenesis and stress acclimation in Arabidopsis

  2009cited by this paper
• Effect of Arabidopsis COP10 ubiquitin E2 enhancement activity across E2 families and functional conservation among its canonical homologues.

  2009cited by this paper
• The COP9 Signalosome Is Required for Light-Dependent Timeless Degradation and Drosophila Clock Resetting

  2009cited by this paper
• Regulation of COP1 nuclear localization by the COP9 signalosome via direct interaction with CSN1.

  2009cited by this paper
• An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

  2009cited by this paper
• Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality.

  2009cited by this paper
• F-box-directed CRL complex assembly and regulation by the CSN and CAND1.

  2009cited by this paper
• The COP9 signalosome: more than a protease.

  2008cited by this paper
• Biochemical Characterization of Arabidopsis Complexes Containing CONSTITUTIVELY PHOTOMORPHOGENIC1 and SUPPRESSOR OF PHYA Proteins in Light Control of Plant Development[W]

  2008cited by this paper
• Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

  2008cited by this paper
• Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 Forms a Nuclear E3 Ubiquitin Ligase with DDB1 and CUL4 That Is Involved in Multiple Plant Developmental Processes[W]

  2008cited by this paper
• The Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome Assembly[W]

  2008cited by this paper
• Characterization of Arabidopsis and Rice DWD Proteins and Their Roles as Substrate Receptors for CUL4-RING E3 Ubiquitin Ligases[W]

  2008cited by this paper
• Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.

  2008cited by this paper
• Novel substrates and functions for the ubiquitin-like molecule NEDD8.

  2008cited by this paper
• Regulation of cullin RING ligases.

  2008cited by this paper
• Auxin Responses in Mutants of the Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC9 Signalosome1[C][W][OA]

  2008cited by this paper
• Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation.

  2007cited by this paper
• Ubiquitin, hormones and biotic stress in plants.

  2007cited by this paper
• Role of the MPN Subunits in COP9 Signalosome Assembly and Activity, and Their Regulatory Interaction with Arabidopsis Cullin3-Based E3 Ligases[W]

  2007cited by this paper
• Mammalian DET1 Regulates Cul4A Activity and Forms Stable Complexes with E2 Ubiquitin-Conjugating Enzymes

  2007cited by this paper
• AXL and AXR1 have redundant functions in RUB conjugation and growth and development in Arabidopsis.

  2007cited by this paper
• Substrate-mediated Regulation of Cullin Neddylation*

  2007cited by this paper
• Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development

  2006cited by this paper
• CONSTITUTIVELY PHOTOMORPHOGENIC1 Is Required for the UV-B Response in Arabidopsis[W]

  2006cited by this paper
• eIF3: a versatile scaffold for translation initiation complexes.

  2006cited by this paper
• Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.

  2006cited by this paper
• Arabidopsis Has Two Redundant Cullin3 Proteins That Are Essential for Embryo Development and That Interact with RBX1 and BTB Proteins to Form Multisubunit E3 Ubiquitin Ligase Complexes in Vivow⃞

  2005cited by this paper
• Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 Signalosome Subunit 5 Is Sufficient to Cause the cop/det/fus Mutant Phenotype in Arabidopsis

  2005cited by this paper
• CSN facilitates Cullin–RING ubiquitin ligase function by counteracting autocatalytic adapter instability

  2005cited by this paper
• The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1.

  2005cited by this paper
• Arabidopsis AtCUL3a and AtCUL3b Form Complexes with Members of the BTB/POZ-MATH Protein Family1

  2005cited by this paper
• COP1 - from plant photomorphogenesis to mammalian tumorigenesis.

  2005cited by this paper
• Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes.

  2004cited by this paper
• The SPA Quartet: A Family of WD-Repeat Proteins with a Central Role in Suppression of Photomorphogenesis in Arabidopsis

  2004cited by this paper
• The ubiquitin 26S proteasome proteolytic pathway.

  2004cited by this paper
• Arabidopsis CAND1, an Unmodified CUL1-Interacting Protein, Is Involved in Multiple Developmental Pathways Controlled by Ubiquitin/Proteasome-Mediated Protein Degradation

  2004cited by this paper
• Related to Ubiquitin 1 and 2 Are Redundant and Essential and Regulate Vegetative Growth, Auxin Signaling, and Ethylene Production in Arabidopsis

  2004cited by this paper
• LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1

  2003cited by this paper
• Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

  2003cited by this paper
• Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo.

  2003cited by this paper
• Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis.

  2003cited by this paper
• The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?

  2003cited by this paper
• The COP9 signalosome.

  2003cited by this paper
• The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity.

  2003cited by this paper
• Structure of the Jab1/MPN domain and its implications for proteasome function.

  2003cited by this paper
• JAMM: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome

  2003cited by this paper
• The diverse roles of ubiquitin and the 26S proteasome in the life of plants

  2003cited by this paper
• NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.

  2002cited by this paper
• Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis.

  2002cited by this paper
• The photomorphogenesis regulator DET1 binds the amino-terminal tail of histone H2B in a nucleosome context.

  2002cited by this paper
• MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

  2002cited by this paper
• Role of Predicted Metalloprotease Motif of Jab1/Csn5 in Cleavage of Nedd8 from Cul1

  2002cited by this paper
• Role of the Arabidopsis RING-H2 Protein RBX1 in RUB Modification and SCF Function Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.003178.

  2002cited by this paper
• Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26S Proteasome

  2002cited by this paper
• CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.

  2002cited by this paper
• Association of the mammalian proto‐oncoprotein Int‐6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome

  2002cited by this paper
• Arabidopsis eIF3e (INT-6) Associates with Both eIF3c and the COP9 Signalosome Subunit CSN7*

  2001cited by this paper
• SKP1–SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase

  2001cited by this paper
• The subunit 1 of the COP9 signalosome suppresses gene expression through its N-terminal domain and incorporates into the complex through the PCI domain.

  2001cited by this paper
• Promotion of NEDD8-CUL1 Conjugate Cleavage by COP9 Signalosome

  2001cited by this paper
• Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

  2001cited by this paper
• Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome

  2001cited by this paper
• PCI complexes: pretty complex interactions in diverse signaling pathways.

  2001cited by this paper
• Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development

  2000cited by this paper
• Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development.

  2000cited by this paper
• Electron microscopy and subunit-subunit interaction studies reveal a first architecture of COP9 signalosome.

  2000cited by this paper
• Characterization of two subunits of Arabidopsis 19S proteasome regulatory complex and its possible interaction with the COP9 complex.

  1999cited by this paper
• The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1.

  1999cited by this paper
• The PCI domain: a common theme in three multiprotein complexes.

  1998cited by this paper
• The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.

  1998cited by this paper
• A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

  1998cited by this paper
• LIGHT CONTROL OF SEEDLING DEVELOPMENT.

  1996cited by this paper
• The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch.

  1996cited by this paper

• CSN2 of COP9 signalosome underpins high temperature adaptation of the diatom Phaeodactylum tricornutum through regulating protein ubiquitination

  2025cites this paper
• CsCIPK20 Improves Tea Plant Cold Tolerance by Modulating Ascorbic Acid Synthesis Through Attenuation of CsCSN5-CsVTC1 Interaction.

  2024cites this paper
• Ascorbate, as a versatile regulator of plant development: practical implications for enhancing crop productivity, quality, and postharvest storage

  2024cites this paper
• Functional role of geminivirus encoded proteins in the host: Past and present

  2024cites this paper
• Role of plastids and mitochondria in the early development of seedlings in dark growth conditions

  2023cites this paper
• The Functions of Chloroplastic Ascorbate in Vascular Plants and Algae

  2023cites this paper
• Haploid induction by nanobody targeted ubiquitin-proteasome-based degradation of EYFP-tagged CENH3 in Arabidopsis thaliana.

  2022cites this paper
• Geminiviruses and their interaction with host proteins

  2021cites this paper
• UBC19 is a new interacting protein of ORANGE for its nuclear localization in Arabidopsis thaliana

  2021cites this paper
• Regulation of micoRNA2111 and its target IbFBK in sweet potato on wounding.

  2020cites this paper
• The COP9 signalosome mediates the Spt23 regulated fatty acid desaturation and ergosterol biosynthesis

  2020cites this paper
• The Proteasome Lid Triggers COP9 Signalosome Activity during the Transition of Saccharomyces cerevisiae Cells into Quiescence

  2019cites this paper
• The Blue-Light Photoreceptor Sfwc-1 Gene Regulates the Phototropic Response and Fruiting-Body Development in the Homothallic Ascomycete Sordaria fimicola

  2019cites this paper
• SNX1-mediated protein recycling: Piecing together the tissue-specific regulation of arabidopsis iron acquisition

  2018cites this paper
• Dancing in the dark: darkness as a signal in plants.

  2017cites this paper
• Cloning and expression analysis of three genes encoding ubiquitins in papaya (Carica papaya L.)

  2016cites this paper
• Elucidation of the genetic basis of variation for stem strength characteristics in bread wheat by Associative Transcriptomics

  2016cites this paper
• Immunodepletion and Immunopurification as Approaches for CSN Research.

  2016cites this paper
• Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology

  2016cites this paper
• The COP 9 signalosome is vital for timely repair of DNA double-strand breaks

  2015cites this paper
• Differential Activation of Inflammatory Pathways in Testicular Macrophages Provides a Rationale for Their Subdued Inflammatory Capacity

  2015influential citation
• The COP9 signalosome is vital for timely repair of DNA double-strand breaks

  2015cites this paper
• Exploring potential new floral organ morphogenesis genes of Arabidopsis thaliana using systems biology approach

  2015cites this paper
• This information is current as Inflammatory Capacity Provides a Rationale for Their Subdued Pathways in Testicular Macrophages Differential Activation of Inflammatory

  2015influential citation
• Pathogen and Circadian Controlled 1 (PCC1) Protein Is Anchored to the Plasma Membrane and Interacts with Subunit 5 of COP9 Signalosome in Arabidopsis

  2014cites this paper
• Signaling: COP9 Signalosome

  2014cites this paper
• COP9 Signalosome Network

  2014cites this paper
• Ectopic Expression of the RING Domain of the Arabidopsis PEROXIN2 Protein Partially Suppresses the Phenotype of the Photomorphogenic Mutant De-Etiolated1

  2014cites this paper
• Effect of Aluminum Treatment on Proteomes of Radicles of Seeds Derived from Al-Treated Tomato Plants

  2014cites this paper
• Screening of cellular proteins that interact with the classical swine fever virus non-structural protein 5A by yeast two-hybrid analysis

  2014cites this paper
• Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.

  2014cites this paper
• Plant Immune Responses Against Viruses: How Does a Virus Cause Disease?[OA]

  2013cites this paper
• Invited Expert Review Cullin-RING Ubiquitin Ligase Family in Plant Abiotic Stress Pathways

  2013cites this paper
• Peroxisomes and photomorphogenesis.

  2013cites this paper
• Arabidopsis CSN5B Interacts with VTC1 and Modulates Ascorbic Acid Synthesis[W]

  2013cites this paper
• Populus euphratica: the transcriptomic response to drought stress

  2013cites this paper
• Cullin-RING ubiquitin ligase family in plant abiotic stress pathways(F).

  2013cites this paper
• Formation of alternative proteasomes: Same lady, different cap?

  2013cites this paper