Acute respiratory distress syndrome (ARDS) remains to pose a high morbidity and mortality without any targeted therapies. Sedation, usually given intravenously, is an important part of clinical practice in intensive care unit (ICU), and the effect of sedatives on patients’ outcomes has been studied intensively. Although volatile anesthetics are not routine sedatives in ICU, preclinical and clinical studies suggested their potential benefit in pulmonary pathophysiology. This review will summarize the current knowledge of ARDS and the role of volatile anesthetic sedation in this setting from both clinical and mechanistic standpoints. In addition, we will review the infrastructure to use volatile anesthetics.
The Use of Volatile Anesthetics as Sedatives for Acute Respiratory Distress Syndrome
S. Koutsogiannaki,M. Shimaoka,Koichi Yuki
Published 2019 in Translational Perioperative and Pain Medicine
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- Publication year
2019
- Venue
Translational Perioperative and Pain Medicine
- Publication date
2019-02-21
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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