epic2 efficiently finds diffuse domains in ChIP-seq data

SUMMARY Data from chromatin immunoprecipitation (ChIP) followed by high throughput sequencing (ChIP-seq) generally contain either narrow peaks or broad and diffusely enriched domains. The SICER ChIP-seq caller has proven adept at finding diffuse domains in ChIP-seq data, but it is slow, requires much memory, needs manual installation steps and is hard to use. epic2 is a complete rewrite of SICER that is focused on speed, low memory overhead and ease-of-use. AVAILABILITY The MIT-licensed code is available at https://github.com/biocore-ntnu/epic2.

• Publication year

  2019

• Venue

  Bioinform.

• Publication date

  2019-11-01

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1093/bioinformatics/btz232PMID 30923821
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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