Top‐down or bottom up: decreased stimulus salience increases responses to predictable stimuli of auditory thalamic neurons

Temporal imprecision leads to deficits in the comprehension of signals in cluttered acoustic environments, and the elderly are shown to use cognitive resources to disambiguate these signals. To mimic ageing in young rats, we delivered sound signals that are temporally degraded, which led to temporally imprecise neural codes. Instead of adaptation to repeated stimuli, with degraded signals, there was a relative increase in firing rates, similar to that seen in aged rats. We interpret this increase with repetition as a repair mechanism for strengthening the internal representations of degraded signals by the higher‐order structures.

• Publication year

  2019

• Venue

  Journal of Physiology

• Publication date

  2019-04-21

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1113/JP277450PMID 30924931PMCID PMC6826238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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