Aquaporins 1, 3 and 5 in Different Tumors, their Expression, Prognosis Value and Role as New Therapeutic Targets

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Pathology and Oncology Research

• Publication date

  2019-03-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s12253-019-00646-9PMID 30927206
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA-MB-231 breast cancer cell line

  2018cited by this paper
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• Expression of AQP3 and AQP5 as a prognostic marker in triple-negative breast cancer.

  2018cited by this paper
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  2017cited by this paper
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  2017cited by this paper
• The association between aquaporin-1 expression, microvessel density and the clinicopathological features of hepatocellular carcinoma

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• Role of Aquaporin 1 Signalling in Cancer Development and Progression

  2017influential reference
• Prognostic implication of aquaporin 1 overexpression in resected lung adenocarcinoma.

  2017cited by this paper
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  2017cited by this paper
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  2017influential reference
• Differential expression of aquaporin‐3 and aquaporin‐5 in pancreatic ductal adenocarcinoma

  2017influential reference
• Knockdown of AQP1 inhibits growth and invasion of human ovarian cancer cells.

  2017cited by this paper
• AQP5 promotes hepatocellular carcinoma metastasis via NF-κB-regulated epithelial-mesenchymal transition.

  2017cited by this paper
• The role of aquaporin-5 in cancer cell migration: A potential active participant.

  2016cited by this paper
• Prognostic Significance of Aquaporin 5 Expression in Non-small Cell Lung Cancer

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• Aquaporin-5: from structure to function and dysfunction in cancer

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• Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3β/β-catenin pathway

  2016influential reference
• The proliferation impairment induced by AQP3 deficiency is the result of glycerol uptake and metabolism inhibition in gastric cancer cells

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• Aquaporin 1 protein expression is associated with BRAF V600 mutation and adverse prognosis in cutaneous melanoma

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• Aquaporins

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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
• Expression of Aquaporin-1, Aquaporin-3, and Aquaporin-5 Correlates with Nodal Metastasis in Colon Cancer

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  2015cited by this paper
• Hyperglycemia Promotes Human Gastric Carcinoma Progression via Aquaporin 3

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• AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinoma

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• Hypoxia Influence Aquaporin 3 (AQP3) and Migration in Oral Squamous Cell Carcinoma (OSCC)

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• Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer

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• Loss of AQP3 protein expression is associated with worse progression-free and cancer-specific survival in patients with muscle-invasive bladder cancer

  2015cited by this paper
• Effects of cetuximab combined with afatinib on the expression of KDR and AQP1 in lung cancer.

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• Aquaporin 3 promotes prostate cancer cell motility and invasion via extracellular signal-regulated kinase 1/2-mediated matrix metalloproteinase-3 secretion.

  2015cited by this paper
• Expression of aquaporin 5 in primary carcinoma and lymph node metastatic carcinoma of non-small cell lung cancer.

  2015cited by this paper
• Aquaporin 3 Expression Predicts Survival in Patients with HER2-positive Early Breast Cancer.

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• Key roles of aquaporins in tumor biology.

  2015influential reference
• Evaluation of Aquaporin-3 Role in Nonmelanoma Skin Cancer: An Immunohistochemical Study*

  2015cited by this paper
• Down-regulated aquaporin 5 inhibits proliferation and migration of human epithelial ovarian cancer 3AO cells

  2014cited by this paper
• Effects of aquaporins on chemosensitivity to cisplatin in ovarian cancer cells

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  2014influential reference
• AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells

  2014cited by this paper
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  2014influential reference
• AQP5 Expression Predicts Survival in Patients with Early Breast Cancer

  2014cited by this paper
• miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer

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• Aquaporins: important but elusive drug targets

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• Urinary concentrations of aquaporin-1 and perilipin-2 in patients with renal cell carcinoma correlate with tumor size and stage but not grade.

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• Critical role of aquaporin 3 on growth of human esophageal and oral squamous cell carcinoma

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• Aquaporins in tumor growth and angiogenesis.

  2010cited by this paper
• [Effect of topotecan on expression of aquaporin protein 5 and nuclear factor-kappaB in ovarian cancer SKOV3 cells].

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• Aquaporins: translating bench research to human disease

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• Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy

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• Aquaporin‐1 activity of plasma membrane affects HT20 colon cancer cell migration

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