Pharmacological models of ADHD

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of neural transmission

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1007/s00702-007-0826-1PMID 17994186
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure

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• Serotoninergics attenuate hyperlocomotor activity in rats. Potential new therapeutic strategy for hyperactivity

  2009cited by this paper
• Glutamate and GABA receptor dysfunction in the fetal alcohol syndrome

  2009cited by this paper
• D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD.

  2007cited by this paper
• Amphetamine and mCPP Effects on Dopamine and Serotonin Striatalin vivo Microdialysates in an Animal Model of Hyperactivity

  2007influential reference
• Maternal Lead Exposure Produces Long-Term Enhancement of Dopaminergic Reactivity in Rat Offspring

  2007cited by this paper
• Disrupting effects of hydroxy-polychlorinated biphenyl (PCB) congeners on neuronal development of cerebellar Purkinje cells: a possible causal factor for developmental brain disorders?

  2007cited by this paper
• Effect of ketanserin and amphetamine on nigrostriatal neurotransmission and reactive oxygen species in Parkinsonian rats. In vivo microdialysis study.

  2006influential reference
• Dose-related effect of methylphenidate on stopping and changing in children with attention-deficit/hyperactivity disorder

  2006cited by this paper
• Prenatal cadmium and ethanol increase amphetamine-evoked dopamine release in rat striatum.

  2006influential reference
• The alpha(2C)-adrenergic receptor mediates hyperactivity of coloboma mice, a model of attention deficit hyperactivity disorder.

  2006cited by this paper
• The α2C-adrenergic receptor mediates hyperactivity of coloboma mice, a model of attention deficit hyperactivity disorder

  2006cited by this paper
• Atomoxetine blocks motor hyperactivity in neonatal 6-hydroxydopamine-lesioned rats: implications for treatment of attention-deficit hyperactivity disorder.

  2005cited by this paper
• The neonate-6-hydroxydopamine-lesioned rat: a model for clinical neuroscience and neurobiological principles.

  2005cited by this paper
• Prenatal alcohol exposure causes attention deficits in male rats.

  2005cited by this paper
• The neuropsychopharmacology of attention-deficit/hyperactivity disorder.

  2005cited by this paper
• Effects of neonatal administration of 5,7-dihydroxytryptamine on locomotor activity

  2004cited by this paper
• Neonatal dopamine lesion in the rat results in enhanced adenylate cyclase activity without altering dopamine receptor binding or dopamine- and adenosine 3′∶5′-monophosphate-regulated phosphoprotein (DARPP-32) immunoreactivity

  2004cited by this paper
• 5-Hydroxytryptamine involvement in the locomotor activity suppressant effects of amphetamine in the mouse

  2004cited by this paper
• 5‐HT2A and α1b‐adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants

  2004cited by this paper
• The effect of low doses of d-amphetamine on drug-induced hyperactivity in the mouse

  2004cited by this paper
• Central noradrenaline depletion antagonizes aspects ofd-amphetamine-induced hyperactivity in the rat

  2004cited by this paper
• Effects ofd-amphetamine and methylphenidate on hyperactivity produced by neonatal 6-hydroxydopamine treatment

  2004cited by this paper
• Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder.

  2003cited by this paper
• Behavioural, pharmacological, morpho-functional molecular studies reveal a hyperfunctioning mesocortical dopamine system in an animal model of attention deficit and hyperactivity disorder.

  2003cited by this paper
• Animal models of attention-deficit hyperactivity disorder.

  2003cited by this paper
• Childhood attention deficit/hyperactivity disorder and alcohol dependence: a 1-year follow-up.

  2003cited by this paper
• Atomoxetine Increases Extracellular Levels of Norepinephrine and Dopamine in Prefrontal Cortex of Rat: A Potential Mechanism for Efficacy in Attention Deficit/Hyperactivity Disorder

  2002cited by this paper
• Effects of dopamine D4 receptor-selective antagonists on motor hyperactivity in rats with neonatal 6-hydroxydopamine lesions

  2002influential reference
• Effects of norepinephrine and serotonin transporter inhibitors on hyperactivity induced by neonatal 6-hydroxydopamine lesioning in rats.

  2002influential reference
• A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyperactivity disorder.

  2002cited by this paper
• In Harm’s Way: Toxic Threats to Child Development

  2002cited by this paper
• Exposure of Pregnant Rats to Manganese: Effect on Levels, Turnover and Release of Biogenic Amines in Brains of Their Offspring

  2002cited by this paper
• Plasticity of Dopamine D4 Receptors in Rat Forebrain: Temporal Association with Motor Hyperactivity Following Neonatal 6-Hydroxydopamine Lesioning

  2002influential reference
• Dopamine may be 'hyper' with respect to noradrenaline metabolism, but 'hypo' with respect to serotonin metabolism in children with attention-deficit hyperactivity disorder.

  2002cited by this paper
• Deviations in brain early serotonergic development as a result of fetal alcohol exposure

  2002cited by this paper
• Amphetamine-induced enhancement of neostriatal in vivo microdialysate dopamine content in rats, quinpirole-primed as neonates.

  2001cited by this paper
• Role of Dopamine D4 Receptors in Motor Hyperactivity Induced by Neonatal 6-Hydroxydopamine Lesions in Rats

  2001influential reference
• Parallels between attention deficit hyperactivity disorder and behavioral deficits produced by neurotoxic exposure in monkeys.

  2000cited by this paper
• Attention deficit/hyperactivity disorder: characteristics, interventions and models.

  2000influential reference
• Pharmacological Alternatives to Psychostimulants for the Treatment of Attention-Deficit/Hyperactivity Disorder

  2000cited by this paper
• Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin2C/2B receptor agonists: a combined in vivo electrophysiological and microdialysis study

  2000cited by this paper
• Clinical psychopharmacology of AD/HD: implications for animal models.

  2000cited by this paper
• Pharmacologic alternatives to psychostimulants for the treatment of attention-deficit/hyperactivity disorder.

  2000cited by this paper
• Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder

  1999cited by this paper
• Attention-deficit/hyperactivity disorder (adhd) as a noradrenergic disorder

  1999cited by this paper
• Reversal of a postnatal alcohol-induced deficit in learned persistence in the rat by d-amphetamine.

  1999cited by this paper
• The Use of Neurotoxins to Lesion Catecholamine-Containing Neurons to Model Clinical Disorders

  1998cited by this paper
• Behavioural hyperactivity in rats following postnatal exposure to sub-toxic doses of polychlorinated biphenyl congeners 153 and 126.

  1998cited by this paper
• Highly selective neurotoxins : basic and clinical applications

  1998cited by this paper
• Serotonin Neural Adaptations to Ontogenetic Loss of Dopamine Neurons in Rat Brain

  1998cited by this paper
• Alleviation of x-irradiation-based deficit in memory-based learning by D-amphetamine: suggestions for attention deficit-hyperactivity disorder.

  1998cited by this paper
• Behavioral effects of low-dose gestational day 11-13 retinoic acid exposure.

  1997cited by this paper
• The Use of Neurotoxins to Lesion Catecholamine-Containing Neurons to Model Clinical Disorders: Approach for Defining Adaptive Neural Mechanisms and Role of Neurotrophic Factors in Brain

  1997cited by this paper
• Severe spatial navigation deficit in the Morris water maze after single high dose of neonatal x-ray irradiation in the rat.

  1997cited by this paper
• Epinephrine and Norepinephrine Act as Potent Agonists at the Recombinant Human Dopamine D4 Receptor

  1997cited by this paper
• Attention deficit hyperactivity disorder, infantile autism, and elevated blood-lead: a possible relationship.

  1996cited by this paper
• The Contribution of α2-Noradrenergic Mechanisms to Prefrontal Cortical Cognitive Function: Potential Significance for Attention-Deficit Hyperactivity Disorder

  1996cited by this paper
• Catecholamines in attention-deficit hyperactivity disorder: current perspectives.

  1996cited by this paper
• Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking

  1996cited by this paper
• Changes in striatal immediate early gene expression following neonatal dopaminergic lesion and effects of intrastriatal dopaminergic transplants.

  1996cited by this paper
• Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

  1996cited by this paper
• Attention deficit hyperactivity disorder, infantile autism, and elevated blood-lead: a possible relationship.

  1996cited by this paper
• Neuroanatomical and functional alterations resulting from early postnatal cerebellar insults in rodents.

  1996cited by this paper
• Functional effects of methylazoxymethanol-induced cerebellar hypoplasia in rats.

  1996cited by this paper
• The contribution of alpha 2-noradrenergic mechanisms of prefrontal cortical cognitive function. Potential significance for attention-deficit hyperactivity disorder.

  1996cited by this paper
• Urinary Catecholamine Excretion and Behavioral Differences in ADHD and Normal Boys

  1996cited by this paper
• Dopamine receptor supersensitivity.

  1995influential reference
• Evaluation of three transporter ligands as quantitative markers of serotonin innervation density in rat brain

  1995cited by this paper
• Enhanced oral activity responses to intrastriatal SKF 38393 andm-CPP are attenuated by intrastriatal mianserin in neonatal 6-OHDA-lesioned rats

  1995cited by this paper
• Transient changes in Fos and GFAP immunoreactivity precede neuronal loss in the rat hippocampus following neonatal anoxia.

  1995cited by this paper
• Behavioral effects of pre‐ and postnatal exposure to individual polychlorinated biphenyl congeners in rats

  1995cited by this paper
• Quantification of the serotonin hyperinnervation in adult rat neostriatum after neonatal 6-hydroxydopamine lesion of nigral dopamine neurons.

  1995cited by this paper
• Validation of the transporter ligand cyanoimipramine as a marker of serotonin innervation density in brain.

  1994cited by this paper
• Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder.

  1994cited by this paper
• Neonatal 6‐Hydroxydopamine and Adult SKF 38393 Treatments Alter Dopamine D1 Receptor mRNA Levels: Absence of Other Neurochemical Associations with the Enhanced Behavioral Responses of Lesioned Rats

  1994influential reference
• Altered dopamine and serotonin metabolism in the dopamine-denervated and serotonin-hyperinnervated neostriatum of adult rat after neonatal 6-hydroxydopamine.

  1994cited by this paper
• Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation.

  1994cited by this paper
• Selective activity enhancement and persistence in weanling rats after hippocampal X-irradiation in infancy: possible relevance for ADHD.

  1994cited by this paper
• Supersensitization of the oral response to SKF 38393 in neonatal 6-hydroxydopamine-lesioned rats is eliminated by neonatal 5,7-dihydroxytryptamine treatment.

  1994cited by this paper
• Blockade of Striatal 5‐Hydroxytryptmine2 Receptors Reduces the Increase in Extracellullar Concentrations of Dopamine Produced by the Amphhetamine analogue 3,4‐Methylenedioxymethamphetamine

  1994cited by this paper
• Proposed animal model of attention deficit hyperactivity disorder.

  1994influential reference
• Comparative evaluation of three ligands of the serotonin transporter as markers of 5-HT innervation density in brain

  1994cited by this paper
• Dose-related effects of a neonatal 6-OHDA lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.

  1993influential reference
• A proposed new nomenclature for 5-HT receptors.

  1993cited by this paper
• c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat.

  1993cited by this paper
• Age-dependence of a 6-hydroxydopamine lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.

  1993influential reference
• Serotonin 5-HT1 and 5-HT2 receptors in adult rat brain after neonatal destruction of nigrostriatal dopamine neurons: a quantitative autoradiographic study.

  1993influential reference
• Ontogenetic SKF 38393 treatments sensitize dopamine D1 receptors in neonatal 6-OHDA-lesioned rats.

  1993influential reference
• Methamphetamine‐Induced Dopamine Overflow and Injury to Striatal Dopamine Terminals: Attenuation by Dopamine D1 or D2 Antagonists

  1993cited by this paper
• Changes of D1 and D2 receptors in adult rat neostriatum after neonatal dopamine denervation: quantitative data from ligand binding, in situ hybridization and iontophoresis.

  1993influential reference
• D1 Dopamine Receptor Binding and mRNA Levels Are Not Altered After Neonatal 6‐Hydroxydopamine Treatment: Evidence Against Dopamine‐Mediated Induction of D1 Dopamine Receptors During Postnatal Development

  1993cited by this paper
• Memory-based learning in preweanling and adult rats after infantile x-irradiation-induced hippocampal granule cell hypoplasia.

  1992cited by this paper
• Augmented sensitivity of D1-dopamine receptors in lateral but not medial striatum after 6-hydroxydopamine-induced lesions in the neonatal rat.

  1992cited by this paper
• Ultrastructural analysis of the serotonin hyperinnervation in adult rat neostriatum following neonatal dopamine denervation with 6-hydroxydopamine.

  1992cited by this paper
• Supersensitization of the oral response to SKF 38393 in neonatal 6-OHDA-lesioned rats is mediated through a serotonin system.

  1992cited by this paper
• Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.

  1992cited by this paper
• In Vivo Neurochemical Evaluation of Striatal Serotonergic Hyperinnervation in Rats Depleted of Dopamine at Infancy

  1992cited by this paper
• Supersensitized oral responses to a serotonin agonist in neonatal 6-OHDA-treated rats.

  1992cited by this paper
• Potentiation of spiperone-induced oral activity in rats after neonatal 6-hydroxydopamine.

  1991cited by this paper

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• Modelling ADHD-Like Phenotypes in Zebrafish.

  2022cites this paper
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  2021cites this paper
• Zebrafish models for attention deficit hyperactivity disorder (ADHD).

  2019cites this paper
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  2019cites this paper
• The Use of Object Recognition Task in Animal Models of Attention-Deficit Hyperactivity Disorder

  2018cites this paper
• Atomoxetine prevents working memory loss in hyperactive rats, mediating plastic changes in prefrontal cortex pyramidal neurons

  2018cites this paper
• Neurotoxin Modeling of Brain Disorders—Life-long Outcomes in Behavioral Teratology

  2016cites this paper
• Neuroteratology and Animal Modeling of Brain Disorders.

  2016cites this paper
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  2016cites this paper
• Perinatal 6-Hydroxydopamine Modeling of ADHD.

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
• Survey of Selective Neurotoxins

  2014cites this paper
• [Neurobiology of attention deficit hyperactivity disorder].

  2014cites this paper
• Neurocognitive deficits in adult ADHD : preclinical and clinical studies

  2014cites this paper
• Attention Deficit Hyperactivity Disorders: Animal Models

  2014cites this paper
• Dysfunkcja ośrodkowego układu serotoninergicznego może prowadzić do zmienionej reakcji biologicznej na leki przeciwbólowe (morfinę).

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  2011influential citation
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  2010cites this paper
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  2010cites this paper
• Animal models of attention deficit/hyperactivity disorder (ADHD): a critical review

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
• Evolution of Neurotoxins: From Research Modalities to Clinical Realities

  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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