Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  European Cells & Materials

• Publication date

  2012-07-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.22203/ECM.V024A09PMID 22828990
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation

  2012cited by this paper
• The expression and function of microRNAs in chondrogenesis and osteoarthritis.

  2012cited by this paper
• Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation.

  2012cited by this paper
• Inhibiting calcineurin activity under physiologic tonicity elevates anabolic but suppresses catabolic chondrocyte markers.

  2012cited by this paper
• Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells.

  2012cited by this paper
• Chondrogenesis of hMSC in affinity-bound TGF-beta scaffolds.

  2012cited by this paper
• TGF β‐1 administration during Ex vivo expansion of human articular chondrocytes in a serum‐free medium redirects the cell phenotype toward hypertrophy

  2012cited by this paper
• Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.

  2012cited by this paper
• Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes.

  2012cited by this paper
• PTHrP isoforms have differing effect on chondrogenic differentiation and hypertrophy of mesenchymal stem cells.

  2012cited by this paper
• DNA Methylation and Demethylation in Mammals*

  2011cited by this paper
• Pharmacological Modulation of Human Mesenchymal Stem Cell Chondrogenesis by a Chemically Oversulfated Polysaccharide of Marine Origin: Potential Application to Cartilage Regenerative Medicine

  2011cited by this paper
• Unique biomaterial compositions direct bone marrow stem cells into specific chondrocytic phenotypes corresponding to the various zones of articular cartilage.

  2011cited by this paper
• Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.

  2011cited by this paper
• Chondrogenesis of Rabbit Mesenchymal Stem Cells in Fibrin/Hyaluronan Composite Scaffold In Vitro

  2011cited by this paper
• MiR‐365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4

  2011cited by this paper
• Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage

  2011cited by this paper
• Wnt inhibitors enhance chondrogenesis of human mesenchymal stem cells in a long-term pellet culture

  2011cited by this paper
• MicroRNA-145 Regulates Chondrogenic Differentiation of Mesenchymal Stem Cells by Targeting Sox9

  2011cited by this paper
• Physical and functional interactions between Runx2 and HIF‐1α induce vascular endothelial growth factor gene expression

  2011influential reference
• An overview of tissue and whole organ decellularization processes.

  2011cited by this paper
• Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo.

  2011cited by this paper
• Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A.

  2011cited by this paper
• Organ engineering based on decellularized matrix scaffolds.

  2011cited by this paper
• A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

  2011cited by this paper
• Smad Signaling Determines Chondrogenic Differentiation of Bone-Marrow-Derived Mesenchymal Stem Cells: Inhibition of Smad1/5/8P Prevents Terminal Differentiation and Calcification

  2011cited by this paper
• The skeleton: a multi-functional complex organ: the growth plate chondrocyte and endochondral ossification.

  2011cited by this paper
• Calcium/calmodulin-dependent protein kinase II activity regulates the proliferative potential of growth plate chondrocytes

  2011influential reference
• Aquaporin-1: a potential membrane channel for facilitating the adaptability of rabbit nucleus pulposus cells to an extracellular matrix environment

  2011cited by this paper
• Biophysical regulation of histone acetylation in mesenchymal stem cells.

  2011influential reference
• Impact of the DNA methyltransferase inhibitor, 5-azacytidine, on chondrocytic phenotype

  2011cited by this paper
• Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy.

  2011cited by this paper
• Chondrogenic potential of bone marrow- and adipose tissue-derived adult human mesenchymal stem cells

  2010cited by this paper
• Smad Signaling determines Chondrogenic Differentiation of Bone-Marrow derived Mesenchymal Stem Cells

  2010cited by this paper
• Oxygen in stem cell biology: a critical component of the stem cell niche.

  2010cited by this paper
• HDAC4 Represses Matrix Metalloproteinase-13 Transcription in Osteoblastic Cells, and Parathyroid Hormone Controls This Repression*

  2010cited by this paper
• Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick.

  2010cited by this paper
• Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages

  2010cited by this paper
• Epigenetic regulation in chondrogenesis.

  2010cited by this paper
• Biomimetic hydrogels for chondrogenic differentiation of human mesenchymal stem cells to neocartilage.

  2010cited by this paper
• Rho kinase-dependent activation of SOX9 in chondrocytes.

  2010influential reference
• Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.

  2010cited by this paper
• Specific microRNA expression during chondrogenesis of human mesenchymal stem cells.

  2010cited by this paper
• HIF-2α - a mediator of osteoarthritis?

  2010cited by this paper
• Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

  2010influential reference
• Type II Collagen Expression Is Regulated by Tissue-specific miR-675 in Human Articular Chondrocytes*

  2010cited by this paper
• In vitro differentiation of chondrogenic ATDC5 cells is enhanced by culturing on synthetic hydrogels with various charge densities.

  2010cited by this paper
• The chondrogenic differentiation of mesenchymal stem cells on an extracellular matrix scaffold derived from porcine chondrocytes.

  2010cited by this paper
• Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis.

  2010cited by this paper
• Decellularized matrices for tissue engineering

  2010cited by this paper
• The Balance of WNT and FGF Signaling Influences Mesenchymal Stem Cell Fate During Skeletal Development

  2010cited by this paper
• The mechanism of mineralization and the role of alkaline phosphatase in health and disease.

  2010cited by this paper
• Identification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage

  2010cited by this paper
• MicroRNA-140 plays dual roles in both cartilage development and homeostasis.

  2010cited by this paper
• A Key Role for Membrane Transporter NKCC1 in Mediating Chondrocyte Volume Increase in the Mammalian Growth Plate

  2010cited by this paper
• Stem Cell Shape Regulates a Chondrogenic Versus Myogenic Fate Through Rac1 and N‐Cadherin

  2010influential reference
• Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

  2010cited by this paper
• Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells

  2010cited by this paper
• WNT5A regulates chondrocyte differentiation through differential use of the CaN/NFAT and IKK/NF-kappaB pathways.

  2010cited by this paper
• Bone Morphogenic Protein 2 Activates Protein Kinase D to Regulate Histone Deacetylase 7 Localization and Repression of Runx2*

  2009cited by this paper
• Histone deacetylase 4 promotes TGF-beta1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy.

  2009cited by this paper
• Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2 A / Histone Deacetylase 4 / MEF 2 Pathway

  2009influential reference
• Development of a new method to harvest chondroprogenitor cells from underneath cartilage defects in the knees

  2009cited by this paper
• MicroRNA‐204 Regulates Runx2 Protein Expression and Mesenchymal Progenitor Cell Differentiation

  2009cited by this paper
• Regulation of Hypoxia-Inducible Factor 2α Signaling by the Stress-Responsive Deacetylase Sirtuin 1

  2009cited by this paper
• Nonlinear Osmotic Properties of the Cell Nucleus

  2009cited by this paper
• Murine mesenchymal progenitor cells from different tissues differentiated via mesenchymal microspheres into the mesodermal direction

  2009cited by this paper
• Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation

  2009cited by this paper
• miR-199a*, a Bone Morphogenic Protein 2-responsive MicroRNA, Regulates Chondrogenesis via Direct Targeting to Smad1*

  2009cited by this paper
• Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells.

  2009cited by this paper
• Variations in the ratios of co-cultured mesenchymal stem cells and chondrocytes regulate the expression of cartilaginous and osseous phenotype in alginate constructs.

  2009cited by this paper
• Proximal events in Wnt signal transduction

  2009cited by this paper
• Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes.

  2009cited by this paper
• TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads.

  2009cited by this paper
• Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway

  2009influential reference
• Gene Expression Profile of Multipotent Mesenchymal Stromal Cells: Identification of Pathways Common to TGFβ3/BMP2-Induced Chondrogenesis

  2009cited by this paper
• Cartilage tissue engineering: towards a biomaterial-assisted mesenchymal stem cell therapy.

  2009cited by this paper
• Nano-approaches in cartilage repair.

  2009cited by this paper
• Calcium-sensing receptor and associated diseases.

  2009cited by this paper
• Laminin‐1 induces E‐cadherin expression in 3‐dimensional cultured breast cancer cells by inhibiting DNA methyltransferase 1 and reversing promoter methylation status

  2009cited by this paper
• Sox9 Inhibits Wnt Signaling by Promoting β-Catenin Phosphorylation in the Nucleus*

  2009cited by this paper
• Effect of osmolarity on glycosaminoglycan production and cell metabolism of articular chondrocyte under three-dimensional culture system.

  2008cited by this paper
• Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells.

  2008influential reference
• Morphogenetic and Regulatory Mechanisms During Developmental Chondrogenesis: New Paradigms for Cartilage Tissue Engineering

  2008influential reference
• Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator.

  2008influential reference
• MicroRNAs Regulate Osteogenesis and Chondrogenesis of Mouse Bone Marrow Stromal Cells

  2008cited by this paper
• The osmotic sensitivity of rat growth plate chondrocytes in situ; clarifying the mechanisms of hypertrophy

  2008cited by this paper
• Engineering cartilage tissue.

  2008cited by this paper
• Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation

  2008cited by this paper
• Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia‐inducible factor (HIF)‐1α

  2008cited by this paper
• Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

  2008cited by this paper
• Histone Deacetylase 5 Acquires Calcium/Calmodulin-Dependent Kinase II Responsiveness by Oligomerization with Histone Deacetylase 4

  2008cited by this paper
• Beta1 integrins regulate chondrogenesis and rock signaling in adipose stem cells.

  2008cited by this paper
• Low Oxygen Expansion Improves Subsequent Chondrogenesis of Ovine Bone-Marrow-Derived Mesenchymal Stem Cells in Collagen Type I Hydrogel

  2008cited by this paper
• Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter.

  2008cited by this paper
• PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs.

  2008cited by this paper
• Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis

  2008cited by this paper
• Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

  2008cited by this paper
• Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells.

  2008cited by this paper
• Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation

  2008cited by this paper

• Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

  2026cites this paper
• A Quantitative Evaluation of the Efficacy of Endochondral Ossification-Based Grafts in Bone Defect Regeneration: An Analysis of Animal Studies.

  2025cites this paper
• In Situ Bioprinting Embryonic-Derived Stem Cells to Repair Human Ex Vivo Chondral Defects

  2025cites this paper
• Biofabrication of an in situ hypoxia-delivery scaffold for cartilage regeneration

  2025cites this paper
• Chondrogenic Differentiation of Stem Cells for Cartilage Regeneration: Advances and Future Perspectives

  2025cites this paper
• G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation

  2025cites this paper
• Substrate Stiffness Modulates Hypertrophic Chondrocyte Reversion and Chondrogenic Phenotype Restoration

  2025cites this paper
• Fructose vs. glucose: modulating stem cell growth and function through sugar supplementation

  2024cites this paper
• Angiogenesis in bone tissue engineering via ceramic scaffolds: A review of concepts and recent advancements.

  2024cites this paper
• Spatiotemporal analysis of multi-scale cell structure in spheroid culture reveals hypertrophic chondrocyte differentiation

  2024cites this paper
• Plasticity Comparison of Two Stem Cell Sources with Different Hox Gene Expression Profiles in Response to Cobalt Chloride Treatment during Chondrogenic Differentiation

  2024cites this paper
• Chondrocyte hypertrophy in the growth plate promotes stress anisotropy affecting long bone development through chondrocyte column formation.

  2024cites this paper
• Comparative Analysis of Hyaline Cartilage Characteristics and Chondrocyte Potential for Articular Cartilage Repair

  2024cites this paper
• In Vitro Induction of Hypertrophic Chondrocyte Differentiation of Naïve MSCs by Strain

  2024cites this paper
• Ca2+/Calmodulin-dependent Protein Kinase II Inhibitor KN-93 Enhances Chondrogenesis of Bone Marrow Mesenchymal Stem Cells and Delays Chondrogenic Hypertrophy

  2023cites this paper
• Suppressing Chondrocyte Hypertrophy to Build Better Cartilage

  2023cites this paper
• Challenges Facing the Translation of Embryonic Stem Cell Therapy for the Treatment of Cartilage Lesions

  2022cites this paper
• The Role of Pericytes in the Articular Environment—a Review

  2022cites this paper
• The combinatory effect of scaffold topography and culture condition: an approach to nucleus pulposus tissue engineering

  2022influential citation
• Biomimetic hydrogel blanket for conserving and recovering intrinsic cell properties

  2022influential citation
• Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies

  2022cites this paper
• LONP1 downregulation with ageing contributes to osteoarthritis via mitochondrial dysfunction.

  2022cites this paper
• Co-culture pellet of human Wharton’s jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study

  2022cites this paper
• Close-to-native bone repair via tissue-engineered endochondral ossification approaches

  2022cites this paper
• COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells

  2022influential citation
• Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.

  2022cites this paper
• Triiodothyronine does not influence in vitro chondrogenic differentiation of adipose tissue-derived stem cells from young female rat

  2022cites this paper
• Soft Hydrogel Environments that Facilitate Cell Spreading and Aggregation Preferentially Support Chondrogenesis of Adult Stem Cells.

  2022cites this paper
• Inhibition of Wnt Pathway Activity as a Treatment Approach for Human Osteoarthritis: A Systematic Review

  2022cites this paper
• Anti-Dlx5 Retards the Progression of Osteoarthritis through Inhibiting Chondrocyte Hypertrophy and Apoptosis

  2022cites this paper
• The Regulation of Growth in Developing, Homeostatic, and Regenerating Tetrapod Limbs: A Minireview

  2022cites this paper
• ALK-5 Inhibitors for Efficient Derivation of Mesenchymal Stem Cells from Human Embryonic Stem Cells

  2022cites this paper
• Anti‐adhesive effect of chondrocyte‐derived extracellular matrix surface‐modified with poly‐L‐lysine

  2021influential citation
• Systematic Comparison of Biomaterials‐Based Strategies for Osteochondral and Chondral Repair in Large Animal Models

  2021cites this paper
• Human Umbilical Cord Mesenchymal Stem Cells Over Platelet Rich Fibrin Scaffold for Mandibular Cartilage Defects Regenerative Medicine

  2021cites this paper
• Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration

  2021cites this paper
• The effect of silk–gelatin bioink and TGF-β3 on mesenchymal stromal cells in 3D bioprinted chondrogenic constructs: A proteomic study

  2021cites this paper
• Hydrostatic Pressure Regulates the Volume, Aggregation and Chondrogenic Differentiation of Bone Marrow Derived Stromal Cells

  2021cites this paper
• Molecular and Cellular Mechanisms of Osteoarthritis in Experimental Arterial Hypertension and Hyperlipidemia

  2021cites this paper
• Platelet-released growth factors protect articular chondrocytes from inflammatory condition.

  2021cites this paper
• Integrative Metabolic Pathway Analysis Reveals Novel Therapeutic Targets in Osteoarthritis*

  2020cites this paper
• Chondrobags: A high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation

  2020cites this paper
• Microencapsulation improves chondrogenesis in vitro and cartilaginous matrix stability in vivo compared to bulk encapsulation.

  2020cites this paper
• Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis

  2020cites this paper
• Protein and Cell Interaction with Bone Substitute Materials

  2020cites this paper
• Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells

  2020cites this paper
• Cartilage Repair Techniques

  2020cites this paper
• Taladegib controls early chondrocyte hypertrophy via inhibiting smoothened/Gli1 pathway.

  2020cites this paper
• Adipose tissue-derived mesenchymal stem cells and chitosan/poly (vinyl alcohol) nanofibrous scaffolds for cartilage tissue engineering

  2020cites this paper
• Investigating the role of culture conditions on hypertrophic differentiation in human cartilage endplate cells

  2020cites this paper
• Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells

  2020cites this paper
• Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes

  2020cites this paper
• Efficient manufacturing of tissue engineered cartilage in vitro by a multiplexed 3D cultured method.

  2020cites this paper
• Atelocollagen promotes chondrogenic differentiation of human adipose-derived mesenchymal stem cells

  2020cites this paper
• TGF-β1/WISP1/Integrin-α interaction mediates human chondrocytes dedifferentiation.

  2020cites this paper
• Role of substitution in bioceramics

  2020cites this paper
• Small nucleolar RNAs in chondorgenic differentiation and osteoarthritis

  2020cites this paper
• In vitro study of cartilage tissue engineering using human adipose-derived stem cells induced by platelet-rich plasma and cultured on silk fibroin scaffold

  2019cites this paper
• Endothelium-dependent molecular mechanisms of articular cartilage and subchondral bone remodeling in conditions of cardiovascular comorbidity

  2019cites this paper
• In Vitro Analysis of the Differentiation Capacity of Postmortally Isolated Human Chondrocytes Influenced by Different Growth Factors and Oxygen Levels

  2019cites this paper
• Neural cell adhesion molecule regulates chondrocyte hypertrophy in chondrogenic differentiation and experimental osteoarthritis

  2019cites this paper
• Articular fibrocartilage - Why does hyaline cartilage fail to repair?

  2019cites this paper
• Continuous Passive Motion Promotes and Maintains Chondrogenesis in Autologous Endothelial Progenitor Cell-Loaded Porous PLGA Scaffolds during Osteochondral Defect Repair in a Rabbit Model

  2019cites this paper
• Chasing Chimeras - The elusive stable chondrogenic phenotype.

  2019cites this paper
• Tissue engineered bone mimetics to study bone disorders ex vivo: Role of bioinspired materials.

  2019cites this paper
• 3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head

  2019cites this paper
• Glutamic Acid-Based Dendritic Peptides for Scaffold-free Cartilage Tissue Engineering.

  2019cites this paper
• Gene-Enhanced Personalized Regenerative Medicine for Bone

  2019cites this paper
• Chondrocyte enlargement is a marker of osteoarthritis severity.

  2019cites this paper
• Enterococcus faecium L-15 Cell-Free Extract Improves the Chondrogenic Differentiation of Human Dental Pulp Stem Cells

  2019cites this paper
• Rapamycin attenuates articular cartilage degeneration by inhibiting β-catenin in a murine model of osteoarthritis

  2019cites this paper
• Role of Norepinephrine in IL-1β-Induced Chondrocyte Dedifferentiation under Physioxia

  2019cites this paper
• Postnatal ex vivo rat model for longitudinal bone growth investigations

  2019cites this paper
• Independent chondrogenic potential of canine bone marrow-derived mesenchymal stem cells in monolayer expansion cultures decreases in a passage-dependent pattern

  2018influential citation
• Perfusion Enhances Hypertrophic Chondrocyte Matrix Deposition, But Not the Bone Formation

  2018cites this paper
• Extracellular matrix deposited by Wharton's jelly mesenchymal stem cells enhances cell expansion and tissue specific lineage potential.

  2018cites this paper
• Effect of Decellularized Cartilage Bovine Scaffold and Hypoxic Condition on Stem Cell Differentiation to Chondrocyte: An In Vitro Study

  2018cites this paper
• Pentosan Polysulfate Sodium Restores the Phenotype of Dedifferentiated Monolayer Canine Articular Chondrocytes Cultured in Alginate Beads

  2018cites this paper
• Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

  2018cites this paper
• MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

  2018cites this paper
• Osteoarthritic human chondrocytes proliferate in 3D co‐culture with mesenchymal stem cells in suspension bioreactors

  2018influential citation
• Enhanced chondrogenic differentiation of dental pulp-derived mesenchymal stem cells in 3D pellet culture system: effect of mimicking hypoxia

  2018cites this paper
• Nonlinear effects of caffeine on the viability, synthesis and gene expression of chondrocytes from the offspring of rats treated during pregnancy.

  2018cites this paper
• Intramembranous ossification and endochondral ossification are impaired differently between glucocorticoid-induced osteoporosis and estrogen deficiency-induced osteoporosis

  2018cites this paper
• Promoting osteogenic differentiation in pre-osteoblasts and reducing tibial fracture healing time using functional nanofibers

  2018cites this paper
• Investigating new genetic susceptibility loci in osteoarthritis

  2018cites this paper
• 3D printed microchannel networks to direct vascularisation during endochondral bone repair.

  2018cites this paper
• In vitro study on role of σB protein in avian reovirus pathogenesis

  2018cites this paper
• Hypoxia regulates RhoA and Wnt/β-catenin signaling in a context-dependent way to control re-differentiation of chondrocytes

  2017cites this paper
• The Good the Bad and the Ugly of Glycosaminoglycans in Tissue Engineering Applications

  2017cites this paper
• A study on role of triiodothyronine (T3) hormone on the improvement of articular cartilage surface architecture.

  2017cites this paper
• Effects of kartogenin on the attenuated nucleus pulposus cell degeneration of intervertebral discs induced by interleukin-1β and tumor necrosis factor-α

  2017cites this paper
• Immune dysfunctionality of replicative senescent mesenchymal stromal cells is corrected by IFNγ priming.

  2017cites this paper
• Strategies to develop endogenous stem cell‐recruiting bioactive materials for tissue repair and regeneration

  2017cites this paper
• Hypoxia for MSC expansion and differentiation : the best way for enhancing

  2017cites this paper
• Current Applications of Mesenchymal Stem Cells for Cartilage Tissue Engineering

  2017influential citation
• IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype

  2017cites this paper
• Influence of Cross-Linkers on the in Vitro Chondrogenesis of Mesenchymal Stem Cells in Hyaluronic Acid Hydrogels.

  2017cites this paper
• Disease Modifying Osteoarthritic Drug, Pentosan Polysulfate Sodium Modulates Cytokine-Induced Osteoarthritic Changes and Promotes Articular Cartilage Tissue Regeneration in vitro [an abstract of dissertation and a summary of dissertation review]

  2017influential citation
• Hypoxia for Mesenchymal Stem Cell Expansion and Differentiation: The Best Way for Enhancing TGFß-Induced Chondrogenesis and Preventing Calcifications in Alginate Beads

  2017cites this paper