Pharmaceutical applications of vibrational chemical imaging and chemometrics: a review.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Pharmaceutical and Biomedical Analysis

• Publication date

  2008-11-04

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jpba.2008.08.014PMID 18819769
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pattern Classification

  2021cited by this paper
• Pattern Classification

  2012cited by this paper
• Measurement of drug agglomerates in powder blending simulation samples by near infrared chemical imaging.

  2008cited by this paper
• Application of Raman microscopy and band-target entropy minimization to identify minor components in model pharmaceutical tablets.

  2008cited by this paper
• Measuring the distribution of density and tabletting force in pharmaceutical tablets by chemical imaging.

  2008cited by this paper
• Near-infrared spectral imaging for quality assurance of pharmaceutical products: Analysis of tablets to assess powder blend homogeneity

  2008cited by this paper
• Self-Modelling Curve Resolution of near Infrared Imaging Data

  2008cited by this paper
• Monitoring galenical process development by near infrared chemical imaging: one case study.

  2008cited by this paper
• Super-resolution and Raman chemical imaging: from multiple low resolution images to a high resolution image.

  2008cited by this paper
• Pharmaceutical manufacturing handbook : regulations and quality

  2008cited by this paper
• Chemical imaging of pharmaceutical granules by Raman global illumination and near-infrared mapping platforms.

  2008cited by this paper
• Content uniformity of pharmaceutical solid dosage forms by near infrared hyperspectral imaging: A feasibility study.

  2007cited by this paper
• Multivariate calibration.

  2007influential reference
• Spectral Pre-Treatments of Hyperspectral near Infrared Images: Analysis of Diffuse Reflectance Scattering

  2007cited by this paper
• Enhancing high-throughput technology and microfluidics with FTIR spectroscopic imaging

  2007cited by this paper
• An In-Depth Analysis of Raman and Near-Infrared Chemical Images of Common Pharmaceutical Tablets

  2007cited by this paper
• A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.

  2007cited by this paper
• “Insight” into Drug Quality: Comparison of Simvastatin Tablets from the US and Canada Obtained via the Internet

  2007cited by this paper
• Hyperspectral imaging – an emerging process analytical tool for food quality and safety control

  2007cited by this paper
• A Practical Algorithm to Remove Cosmic Spikes in Raman Imaging Data for Pharmaceutical Applications

  2007cited by this paper
• Practical Limits of Spatial Resolution in Diffuse Reflectance NIR Chemical Imaging

  2007cited by this paper
• Process analytical technology: chemometric analysis of Raman and near infra-red spectroscopic data for predicting physical properties of extended release matrix tablets.

  2007cited by this paper
• Effect of moisture and pressure on tablet compaction studied with FTIR spectroscopic imaging.

  2007cited by this paper
• In situ high-throughput study of drug polymorphism under controlled temperature and humidity using FT-IR spectroscopic imaging

  2007cited by this paper
• Combined Fourier-transform infrared imaging and desorption electrospray-ionization linear ion-trap mass spectrometry for analysis of counterfeit antimalarial tablets

  2007cited by this paper
• Optimisation of Magnification Levels for near Infrared Chemical Imaging of Blending of Pharmaceutical Powders

  2007cited by this paper
• Raman Chemical Imaging for Ingredient-specific Particle Size Characterization of Aqueous Suspension Nasal Spray Formulations: A Progress Report

  2007cited by this paper
• Standardization of line‐scan NIR imaging systems

  2007cited by this paper
• Applications of vibrational spectroscopy in pharmaceutical research and development

  2007cited by this paper
• Attenuated Total Reflection Fourier Transform Infrared Imaging with Variable Angles of Incidence: A Three-Dimensional Profiling of Heterogeneous Materials

  2007cited by this paper
• NIR chemical imaging to guide/support BMS-561389 tablet formulation development.

  2007cited by this paper
• Macro FTIR imaging in transmission under a controlled environment

  2006cited by this paper
• Identification of primary tumors of brain metastases by SIMCA classification of IR spectroscopic images.

  2006cited by this paper
• ATR-FTIR spectroscopic imaging with expanded field of view to study formulations and dissolution.

  2006cited by this paper
• Attenuated Total Internal Reflection Infrared Microspectroscopic Imaging Using a Large-Radius Germanium Internal Reflection Element and a Linear Array Detector

  2006cited by this paper
• Screening of compound feeds using NIR hyperspectral data

  2006cited by this paper
• High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data.

  2006cited by this paper
• An evaluation of 2D-wavelet filters for estimation of differences in textures of pharmaceutical tablets

  2006cited by this paper
• Hyperspectral NIR image regression part II: dataset preprocessing diagnostics

  2006cited by this paper
• Bayesian analysis of spectral mixture data using Markov Chain Monte Carlo Methods

  2006cited by this paper
• Hyperspectral NIR imaging for calibration and prediction: a comparison between image and spectrometer data for studying organic and biological samples.

  2006cited by this paper
• Artificial neural networks as supervised techniques for FT‐IR microspectroscopic imaging

  2006cited by this paper
• Effects of including spatial information in clustering multivariate image data

  2006cited by this paper
• Raman Mapping of Low-Content API Pharmaceutical Formulations. I. Mapping of Alprazolam in Alprazolam/Xanax Tablets

  2006cited by this paper
• Defining a Strategy for Chemical Imaging of Industrial Pharmaceutical Samples on Raman Line-Mapping and Global Illumination Instruments

  2006cited by this paper
• Characterization of chloramphenicol palmitate drug polymorphs by Raman mapping with multivariate image segmentation using a spatial directed agglomeration clustering method.

  2006cited by this paper
• Spatial resolution in infrared microspectroscopic imaging of tissues.

  2006cited by this paper
• Fuzzy Clustering of Raman Spectral Imaging Data with a Wavelet-Based Noise-Reduction Approach

  2006cited by this paper
• Drug Characterization in Low Dosage Pharmaceutical Tablets Using Raman Microscopic Mapping

  2006cited by this paper
• Chemical images: Technical approaches and issues

  2006cited by this paper
• Near-Infrared Imaging for Studying Homogeneity of Protein-Sugar Mixtures

  2006cited by this paper
• Multi- and megavariate data analysis

  2006cited by this paper
• Analyzing Raman Maps of Pharmaceutical Products by Sample—Sample Two-Dimensional Correlation

  2005cited by this paper
• Process analytical technology

  2005cited by this paper
• Automatic masking in multivariate image analysis using support vector machines

  2005cited by this paper
• Clustering multispectral images: a tutorial

  2005cited by this paper
• NIR spectrometry for counterfeit drug detection - A feasibility study

  2005cited by this paper
• Pharmaceutical applications of Mid-IR and Raman spectroscopy.

  2005cited by this paper
• Hyperspectral NIR image regression part I: calibration and correction

  2005cited by this paper
• Quality assessment of internet pharmaceutical products using traditional and non-traditional analytical techniques.

  2005cited by this paper
• Enhancement of Infrared Spectral Images for Maximizing Chemical Information by Minimizing Baseline Interferences

  2005cited by this paper
• Discriminant image resolution: a novel multivariate image analysis method utilizing a spatial classification constraint in addition to bilinear nonnegativity

  2005cited by this paper
• Spectroscopic Imaging of Compacted Pharmaceutical Tablets

  2005cited by this paper
• Two-dimensional correlation spectroscopy as a tool for analyzing vibrational images

  2005cited by this paper
• Infrared hyperspectral imaging for qualitative analysis of pharmaceutical solid forms

  2005cited by this paper
• Release of poorly soluble drugs from HPMC tablets studied by FTIR imaging and flow-through dissolution tests.

  2005cited by this paper
• Characterizing process effects on pharmaceutical solid forms using near-infrared spectroscopy and infrared imaging.

  2005cited by this paper
• Identifying and Mapping Surface Amorphous Domains

  2005cited by this paper
• Introducing multi‐dimensional ‘hybrid wavelets’ for enhanced evaluation of hyperspectral image cubes and multi‐way data sets

  2005cited by this paper
• Local rank analysis for exploratory spectroscopic image analysis. Fixed Size Image Window-Evolving Factor Analysis

  2005cited by this paper
• A new procedure for the modelling and representation of classes in multivariate images

  2005cited by this paper
• Fourier transform infrared imaging for high-throughput analysis of pharmaceutical formulations.

  2005cited by this paper
• Extended Multiplicative Signal Correction as a Tool for Separation and Characterization of Physical and Chemical Information in Fourier Transform Infrared Microscopy Images of Cryo-Sections of Beef Loin

  2005cited by this paper
• Multivariate data analysis for Raman imaging of a model pharmaceutical tablet

  2005cited by this paper
• Classification of human gliomas by infrared imaging spectroscopy and chemometric image processing

  2005cited by this paper
• Extracting process-related information from pharmaceutical dosage forms using near infrared microscopy

  2004cited by this paper
• A comparison of Raman chemical images produced by univariate and multivariate data processing—a simulation with an example from pharmaceutical practice

  2004cited by this paper
• Imaging of colorectal adenocarcinoma using FT-IR microspectroscopy and cluster analysis.

  2004cited by this paper
• Validation of Macroscopic Attenuated Total Reflection-Fourier Transform Infrared Imaging to Study Dissolution of Swelling Pharmaceutical Tablets

  2004cited by this paper
• A Spectral Identity Mapper for Chemical Image Analysis

  2004cited by this paper
• Combined approach of FTIR imaging and conventional dissolution tests applied to drug release.

  2004cited by this paper
• Magic Bullet Gone Astray: Medications and the Internet

  2004cited by this paper
• Utilizing three‐dimensional wavelet transforms for accelerated evaluation of hyperspectral image cubes

  2004cited by this paper
• Spectroscopic imaging and chemometrics: a powerful combination for global and local sample analysis

  2004cited by this paper
• An innovative design of compaction cell for in situ FT-IR imaging of tablet dissolution

  2004cited by this paper
• Visualisation of the heterogeneous water sorption in a pharmaceutical formulation under controlled humidity via FT-IR imaging

  2004cited by this paper
• Principles and methodologies in self-modeling curve resolution

  2004cited by this paper
• Combination of support vector machines (SVM) and near‐infrared (NIR) imaging spectroscopy for the detection of meat and bone meal (MBM) in compound feeds

  2004cited by this paper
• Hyperspectral imaging: calibration problems and solutions

  2004cited by this paper
• Digital Imaging for Online Monitoring and Control of Industrial Snack Food Processes

  2003cited by this paper
• Raman microspectroscopy: a comparison of point, line, and wide-field imaging methodologies.

  2003cited by this paper
• The use of FT-IR imaging as an analytical tool for the characterization of drug delivery systems.

  2003cited by this paper
• Infrared Multispectral Imaging: Principles and Instrumentation

  2003cited by this paper
• Analysis of video images from a gas–liquid transfer experiment: a comparison of PCA and PARAFAC for multivariate image analysis

  2003cited by this paper
• Chemometrics applied to unravel multicomponent processes and mixtures: Revisiting latest trends in multivariate resolution

  2003cited by this paper
• The Image Processing Handbook, 4th Edition

  2003cited by this paper
• Chemometrics and intelligent laboratory systems Plastic identification by remote sensing spectroscopic NIR imaging using kernel partial least squares ( KPLS )

  2003cited by this paper
• Multivariate Curve Resolution Methods in Imaging Spectroscopy: Influence of Extraction Methods and Instrumental Perturbations

  2003cited by this paper
• Multi-way methods in image analysis : Relationships and applications

  2003cited by this paper
• Applications of attenuated total reflection infrared spectroscopic imaging to pharmaceutical formulations.

  2003cited by this paper

• Current demands for standardization of Indian medicinal plants: A critical review

  2025cites this paper
• A process analyzer assembly for real-time automated near-infrared, Raman, and proton nuclear magnetic resonance spectroscopic monitoring enhanced by heterocovariance spectroscopy and chemometry applied to a Schiff base formation

  2025cites this paper
• Synthesis, Investigation, Biological Evaluation, and Application of Coordination Compounds with Schiff Base—A Review

  2025cites this paper
• TRIPS, Human Rights, and Environmental Protection: A Legal Analysis

  2025cites this paper
• Exploring Hot Melt Extrusion from Process to Product with Methodologies and Drug-Delivery Applications: A Review.

  2025cites this paper
• Plant derivative extracts'(Brahmastra) spectral characterization and their impact on Lipaphis erysimi and natural enemies in oilseed-mustard under organic farming conditions

  2025cites this paper
• A pre-training enhanced deep learning framework for robust sparse unmixing in chemical imaging.

  2025cites this paper
• Contemporary Trends in Analytical Spectroscopy and Integrating Qbd Principles for Enhanced Method Development

  2024cites this paper
• Diffusion and Exchange Kinetics of Microparticle Formulations by Spatial Fourier Transform Fluorescence Recovery after Photobleaching with Patterned Illumination.

  2024cites this paper
• Critical evaluation of hyperspectral imaging technology for detection and quantification of microplastics in soil.

  2024cites this paper
• A Quantitative Chemometric Study of Pharmaceutical Tablet Formulations Using Multi-Spectroscopic Fibre Optic Probes

  2024cites this paper
• PCA, PLS, and MCR-ALS applied to the analysis of miscibility and quantification of cupuassu butter, passion fruit oil and sacha inchi oil blended in cocoa butter

  2024cites this paper
• Suitability of Fourier transform infrared microscopy for the diagnosis of cystic echinococcosis in human tissue sections

  2024cites this paper
• Hyperspectral retinal imaging biomarkers of ocular and systemic diseases

  2024cites this paper
• High-throughput optimisations for 3D chemical imaging of pharmaceutical solid oral dosage forms.

  2024cites this paper
• Study of the photobleaching phenomenon to optimize acquisition of 3D and 4D fluorescence images. A special scenario for trilinear and quadrilinear models

  2023cites this paper
• UST-Net: A U-Shaped Transformer Network Using Shifted Windows for Hyperspectral Unmixing

  2023cites this paper
• Quantitative study of ternary polycrystalline mixtures of prulifloxacin based on Raman spectra and Raman imaging maps.

  2023cites this paper
• SIGMA: Spectral Interpretation Using Gaussian Mixtures and Autoencoder

  2023cites this paper
• Detection of Oxacillin/Cefoxitin Resistance in Staphylococcus aureus Present in Recurrent Tonsillitis

  2023influential citation
• Fast Compressive Raman Imaging of Polymorph Molecules and Excipients in Pharmaceutical Tablets.

  2022cites this paper
• Evaluation of laser direct infrared imaging for rapid analysis of pharmaceutical tablets.

  2022cites this paper
• Method development and validation of a near-infrared spectroscopic method for in-line API quantification during fluidized bed granulation.

  2022cites this paper
• Novel aspects of Raman spectroscopy in skin research

  2022cites this paper
• Microchemical Imaging of Oil Paint Composition and Degradation : State-ofthe-Art and Future

  2022cites this paper
• A feasibility study on improving the non-invasive detection accuracy of bottled Shuanghuanglian oral liquid using near infrared spectroscopy.

  2022cites this paper
• Determination of the Deep Optical Properties of Healthy and Diseased Skin Using Diffuse Reflectance Spectroscopy

  2022cites this paper
• Analysis of Over-Granulated Particles using Near-Infrared Chemical Imaging and Attenuated Total Reflectance-Infrared Techniques.

  2022cites this paper
• Hyperspectral Unmixing Based on Nonnegative Matrix Factorization: A Comprehensive Review

  2022cites this paper
• Chemometric Tools in the Analysis of Pharmaceutics Samples: a Comparison Among Several Multivariate Calibration Methods

  2022cites this paper
• Rapid detection of adulteration of olive oil with soybean oil combined with chemometrics by Fourier transform infrared, visible-near-infrared and excitation-emission matrix fluorescence spectroscopy: A comparative study.

  2022cites this paper
• Use of NIR spectroscopy and multivariate regression for prediction of pentosan content in wood pulp

  2022cites this paper
• Evaluation of the Miscibility of Novel Cocoa Butter Equivalents by Raman Mapping and Multivariate Curve Resolution–Alternating Least Squares

  2021cites this paper
• Prediction of Coating Adhesion on Laser-Cleaned Metal Surfaces of Battery Cells Using Hyperspectral Imaging and Machine Learning

  2021cites this paper
• Application of reverse engineering in the field of pharmaceutical tablets using Raman mapping and chemometrics.

  2021cites this paper
• Application of mid‐infrared microscopic imaging for the diagnosis and classification of human lymphomas

  2021cites this paper
• In Vitro and In Vivo Multispectral Photoacoustic Imaging for the Evaluation of Chromophore Concentration

  2021cites this paper
• Development of NIR spectroscopy based prediction models for nutritional profiling of pearl millet (Pennisetum glaucum (L.)) R.Br: A chemometrics approach

  2021cites this paper
• Potential of Raman Spectroscopy in Facilitating Pharmaceutical Formulations DevelopmPotential of Raman Spectroscopy in Facilitating Pharmaceutical Formulations Development - An AI perspective.

  2021cites this paper
• Forensic analysis of anabolic steroids tablets composition using attenuated total reflection Fourier transform infrared microspectroscopy (µATR‐FTIR) mapping

  2021cites this paper
• Assessment of Quality of Azithromycin, a Macrolide Antibiotic by NMR Spectroscopy

  2021cites this paper
• Multivariate Analysis of the Composition of Pharmaceutical Products Based on Terahertz Time-Domain Spectroscopy

  2021cites this paper
• Geodesic simplex based multiobjective endmember extraction for nonlinear hyperspectral mixtures

  2021cites this paper
• Detectability & quantification of low-dose glimepiride in a fixed-dose combination using Raman imaging

  2021cites this paper
• Raman Imaging as a powerful tool to elucidate chemical processes in a matrix: Medicated chewing gums with nicotine.

  2021cites this paper
• An overview of regression methods in hyperspectral and multispectral imaging

  2020cites this paper
• Molecular (Raman, NIR, and FTIR) spectroscopy and multivariate analysis in consumable products analysis1

  2020cites this paper
• Pattern recognition: An effective tool for quality assessment of herbal medicine based on chemical information

  2020cites this paper
• Chemical drug analysis

  2020cites this paper
• Non-invasive detection technologies of solid foreign matter and their applications to lyophilized pharmaceutical products: A review.

  2020cites this paper
• The use of chemometrics in combination with molecular spectroscopic and chromatographic methods for authentication of Curcuma species: a review

  2020cites this paper
• Raman chemical imaging of intact non-flat tablets in regular and high-confocal mode

  2020cites this paper
• Review of NIR spectroscopy methods for nondestructive quality analysis of oilseeds and edible oils

  2020cites this paper
• Comparison of Raman and Near-Infrared Chemical Mapping for the Analysis of Pharmaceutical Tablets

  2020cites this paper
• Multiobjective Endmember Extraction Based on Bilinear Mixture Model

  2020cites this paper
• In Vivo Spectral Distortions of Infrared Luminescent Nanothermometers Compromise Their Reliability.

  2020cites this paper
• Near‐Infrared Spectroscopy Application to the Pharmaceutical Industry

  2020cites this paper
• Morphological evaluation of low-dose midazolam granules by laser Raman microscopy.

  2020cites this paper
• Effect of plant sample preparation and measuring methods on ATR-FTIR spectra results

  2020cites this paper
• Terahertz Time of Flight Spectroscopy as a Coating Thickness Reference Method for Partial Least Squares Near Infrared Spectroscopy Models.

  2020cites this paper
• Non-Local Meets Global: An Iterative Paradigm for Hyperspectral Image Restoration

  2020cites this paper
• Applying chemometrics to study battery materials: Towards the comprehensive analysis of complex operando datasets

  2019cites this paper
• New designed special cells for Raman mapping of the disintegration process of pharmaceutical tablets

  2019cites this paper
• A comparative study of image processing thresholding algorithms on residual oxide scale detection in stainless steel production lines

  2019cites this paper
• Reduction of the influence of film thickness on diffuse reflectance spectroscopy measurement of the tongue.

  2019cites this paper
• Characterization of Zinc Carboxylates in an Oil Paint Test Panel

  2019cites this paper
• Characterization of acoustic emission analysis in applications for inhalation device performance assessment

  2019cites this paper
• Recent applications of infrared (IR) and Raman chemical imaging in plant materials

  2019cites this paper
• A novel multivariate curve resolution-alternating least squares (MCR-ALS) methodology for application in hyperspectral Raman imaging analysis.

  2019cites this paper
• Development of a polarized hyperspectral imaging system for investigation of absorption and scattering properties

  2019cites this paper
• A polarized hyperspectral imaging system for in vivo detection: Multiple applications in sunflower leaf analysis

  2019cites this paper
• Vertical shear alters chemical front speed in thin-layer flows

  2019cites this paper
• Manufacturing and Quality Assurance

  2019cites this paper
• Evaluation of chemometric approaches for polymorphs quantification in tablets using near‐infrared hyperspectral images

  2019cites this paper
• Fast Raman chemical imaging of tablets with non-flat surfaces.

  2019cites this paper
• Application of FTIR spectroscopy and multivariate calibration for determination of Acid Orange 7 and Sudan II in blusher products

  2019cites this paper
• Supervised classification of monomodal and multimodal hyperspectral data in vibrational microspectroscopy: A comprehensive comparison

  2019cites this paper
• OCM 2019 - Optical Characterization of Materials : Conference Proceedings

  2019cites this paper
• Brillouin Light Scattering: Development of a Near Century-Old Technique for Characterizing the Mechanical Properties of Materials

  2019cites this paper
• Identification of Plants Content by Infrared Reflection Process Using Patch Antenna

  2019cites this paper
• Calibration Transfer from Micro NIR Spectrometer to Hyperspectral Imaging: a Case Study on Predicting Soluble Solids Content of Bananito Fruit (Musa acuminata)

  2018cites this paper
• Non-Local Meets Global: An Integrated Paradigm for Hyperspectral Denoising

  2018cites this paper
• The employment of spectroscopic techniques coupled with chemometrics for authentication analysis of halal pharmaceuticals

  2018cites this paper
• Hyperspectral Imaging Using Laser Excitation for Fast Raman and Fluorescence Hyperspectral Imaging for Sorting and Quality Control Applications

  2018cites this paper
• Raman chemical imaging for spectroscopic screening and direct quantification of falsified drugs

  2018cites this paper
• A Broadly Tunable Surface Plasmon-Coupled Wavelength Filter for Visible and Near Infrared Hyperspectral Imaging

  2018cites this paper
• SERS Research Applied to Polymer Based Nanocomposites

  2018cites this paper
• Comparison of different chemometric methods to extract chemical and physical information from Raman images of homogeneous and heterogeneous semi‐solid pharmaceutical formulations

  2018cites this paper
• Advances in rapid drug detection technology

  2018cites this paper
• Characterization of pharmaceutically relevant materials at the solid state employing chemometrics methods

  2018cites this paper
• INFRARED REGION USING COMPRESSED SENSING METHODS

  2018cites this paper
• HYPER-Tools. A graphical user-friendly interface for hyperspectral image analysis

  2018cites this paper
• Multivariate Curve Resolution–Alternating Least Squares (MCR-ALS) with Raman Imaging Applied to Lunar Meteorites

  2018cites this paper
• Process Analytical Technology (PAT)

  2018cites this paper
• Chemometrics coupled to vibrational spectroscopy and spectroscopic imaging for the analysis of solid-phase pharmaceutical products: A brief review on non-destructive analytical methods

  2018cites this paper
• Clinical infrared microscopic imaging: An overview.

  2018cites this paper
• [Applications of Raman Spectroscopy on Quality Control of Hospital Formulations].

  2018cites this paper
• Engineering plants for tomorrow: how high-throughput phenotyping is contributing to the development of better crops

  2018cites this paper
• Raman imaging from microscopy to macroscopy: Quality and safety control of biological materials

  2017cites this paper
• Chemometric approaches to low-content quantification (LCQ) in solid-state mixtures using Raman mapping spectroscopy

  2017cites this paper