A Three-Dimensional Computer Model of Four Hypothetical Mechanisms Protecting Biofilms from Antimicrobials

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Applied and Environmental Microbiology

• Publication date

  2006-03-01

• Fields of study

  Biology, Chemistry, Computer Science, Environmental Science, Medicine

• Identifiers
  DOI 10.1128/AEM.72.3.2005-2013.2006PMID 16517649PMCID PMC1393201
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A 3D model of antimicrobial action on biofilms

  2005cited by this paper
• Modeling physiological resistance in bacterial biofilms

  2005cited by this paper
• Adaptive responses to antimicrobial agents in biofilms.

  2005cited by this paper
• Modeling Antibiotic Tolerance in Biofilms by Accounting for Nutrient Limitation

  2004cited by this paper
• Contributions of Antibiotic Penetration, Oxygen Limitation, and Low Metabolic Activity to Tolerance of Pseudomonas aeruginosa Biofilms to Ciprofloxacin and Tobramycin

  2003cited by this paper
• Role of Nutrient Limitation and Stationary-Phase Existence in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin

  2003cited by this paper
• Understanding biofilm resistance to antibacterial agents

  2003cited by this paper
• A computer investigation of chemically mediated detachment in bacterial biofilms.

  2003cited by this paper
• Penetration of Rifampin through Staphylococcus epidermidis Biofilms

  2002cited by this paper
• Mechanisms of antibiotic resistance in bacterial biofilms.

  2002cited by this paper
• Riddle of Biofilm Resistance

  2001cited by this paper
• Biofilm penetration and disinfection efficacy of alkaline hypochlorite and chlorosulfamates

  2001cited by this paper
• Mechanisms of biofilm resistance to antimicrobial agents.

  2001cited by this paper
• Biofilms and Planktonic Cells of Pseudomonas aeruginosa Have Similar Resistance to Killing by Antimicrobials

  2001cited by this paper
• Antibiotic resistance of bacteria in biofilms.

  2001cited by this paper
• A Dose-Response Study of Antibiotic Resistance inPseudomonas aeruginosa Biofilms

  2000cited by this paper
• Modeling biocide action against biofilms

  2000cited by this paper
• Modeling biofilm antimicrobial resistance.

  2000cited by this paper
• Biofilm control by antimicrobial agents

  2000cited by this paper
• A three-dimensional numerical study on the correlation of spatial structure, hydrodynamic conditions, and mass transfer and conversion in biofilms

  2000cited by this paper
• Reduced susceptibility of thin Pseudomonas aeruginosa biofilms to hydrogen peroxide and monochloramine

  2000cited by this paper
• Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin

  2000cited by this paper
• A Dose-Response Study of Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

  2000cited by this paper
• Distribution of Bacterial Growth Activity in Flow-Chamber Biofilms

  1999cited by this paper
• In vitro bactericidal activities of beta-lactamases, amikacin, and fluoroquinolones against Pseudomonas aeruginosa biofilm in artificial urine.

  1999cited by this paper
• Treatment of metals-contaminated wastewaters by use of natural zeolites

  1999cited by this paper
• Simulation of multispecies biofilm development in three dimensions

  1999cited by this paper
• Discrete-differential modelling of biofilm structure

  1999cited by this paper
• Spatial Physiological Heterogeneity inPseudomonas aeruginosa Biofilm Is Determined by Oxygen Availability

  1998cited by this paper
• Changes in the biocide susceptibility of Staphylococcus epidermidis and Escherichia coli cells associated with rapid attachment to plastic surfaces

  1998cited by this paper
• Effect of Growth Rate on Resistance ofCandida albicans Biofilms to Antifungal Agents

  1998cited by this paper
• BacSim, a simulator for individual-based modelling of bacterial colony growth.

  1998cited by this paper
• A new combined differential-discrete cellular automaton approach for biofilm modeling: application for growth in gel beads.

  1998cited by this paper
• Permeation of antimicrobial agents through Pseudomonas aeruginosa biofilms: a simple method.

  1997cited by this paper
• A unifying hypothesis for the structure of microbial biofilms based on cellular automaton models

  1997cited by this paper
• Spatial Variations in Growth Rate within Klebsiellapneumoniae Colonies and Biofilm

  1996cited by this paper
• Theoretical aspects of antibiotic diffusion into microbial biofilms

  1996cited by this paper
• Mathematical model of β-lactam penetration into a biofilm of Pseudomonas aeruginosa while undergoing simultaneous inactivation by released β-lactamases

  1996cited by this paper
• Mathematical model of beta-lactam penetration into a biofilm of Pseudomonas aeruginosa while undergoing simultaneous inactivation by released beta-lactamases.

  1996cited by this paper
• Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms

  1994cited by this paper
• Effects of biofilm structures on oxygen distribution and mass transport

  1994cited by this paper
• Vancomycin penetration into biofilm covering infected prostheses and effect on bacteria.

  1994cited by this paper
• Biofilm accumulation model that predicts antibiotic resistance of Pseudomonas aeruginosa biofilms

  1994cited by this paper
• Diffusion of rifampin and vancomycin through a Staphylococcus epidermidis biofilm

  1993cited by this paper
• Effect of biofilm culture upon the susceptibility of Staphylococcus epidermidis to tobramycin.

  1992cited by this paper
• Susceptibility of Pseudomonas aeruginosa and Escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate.

  1991cited by this paper
• Iodine susceptibility of pseudomonads grown attached to stainless steel surfaces.

  1990cited by this paper
• Effect of growth-rate on resistance of gram-negative biofilms to cetrimide.

  1990cited by this paper
• The penetration of antibiotics into aggregates of mucoid and non-mucoid Pseudomonas aeruginosa.

  1989cited by this paper
• Resistance of bacterial biofilms to antibiotics: a growth-rate related effect?

  1988cited by this paper
• A 3D model of antimicrobial action on biofilms

  year unknowncited by this paper
• Biofilm penetration and disinfection efficacy of alkaline hypochlorite and chlorosulfamates

  year unknowncited by this paper

• Naringenin as a Potent Natural Biofilm Inhibitor of Pseudomonas aeruginosa in Diabetic Foot Ulcers Through lasR Competitive Inhibition

  2025cites this paper
• Nanomaterial-enabled anti-biofilm strategies: new opportunities for treatment of bacterial infections.

  2025cites this paper
• Light-mediated activation of nitric oxide and antibacterial polymers for anti-biofilm applications.

  2025cites this paper
• The chronic wound milieu changes essential oils' antibiofilm activity—an in vitro and larval model study

  2024cites this paper
• Chewing Pomegranate Fruit as an Adjuvant to Fight Against Early Childhood Caries

  2024cites this paper
• Unveiling the Mechanisms for Campylobacter jejuni Biofilm Formation Using a Stochastic Mathematical Model

  2024cites this paper
• Modelling Plasmid-Mediated Horizontal Gene Transfer in Biofilms

  2024cites this paper
• Effect of hydroalcoholic extract of whole pomegranate fruit on cariogenic bacteria and its clinical effect on dental plaque formation in 8–10-year-old children

  2023cites this paper
• Biofilm.jl: A fast solver for one-dimensional biofilm chemistry and ecology

  2023cites this paper
• Enhanced antibacterial efficacy against antibiotic-resistant bacteria via nitric oxide-releasing ampicillin polymer substrates.

  2023cites this paper
• Simulation of catalase-dependent tolerance of microbial biofilm to hydrogen peroxide with a biofilm computer model

  2023cites this paper
• Chronic Wound Milieu Challenges Essential Oils’ Antibiofilm Activity

  2023cites this paper
• Prevotella: An Insight into Its Characteristics and Associated Virulence Factors.

  2022cites this paper
• Infections nosocomiales en chirurgie orthopédique

  2022cites this paper
• pH variation in medical implant biofilms: Causes, measurements, and its implications for antibiotic resistance

  2022cites this paper
• Catheter-associated urinary tract infection: an overview

  2022cites this paper
• Optimal dose of lactoferrin reduces the resilience of in vitro Staphylococcus aureus colonies

  2022cites this paper
• Environmental stressors alter the susceptibility of microorganisms to biocides in upstream oil and gas systems

  2022cites this paper
• Infecciones nosocomiales en cirugía ortopédica

  2022cites this paper
• Biofouling and Mitigation Methods: A Review

  2022cites this paper
• Quality of tap water in an urban agglomeration: 2-years’ monitoring study in Wrocław, Poland

  2021cites this paper
• Nuclear Medicine Imaging of Non-orthopedic or Cardiovascular Implantable Device Infection

  2021cites this paper
• Listeria monocytogenes Biofilms in the Food Industry: Is the Current Hygiene Program Sufficient to Combat the Persistence of the Pathogen?

  2021cites this paper
• How Do Polymer Coatings Affect the Growth and Bacterial Population of a Biofilm Formed by Total Human Salivary Bacteria?—A Study by 16S-RNA Sequencing

  2021cites this paper
• Effect of inertial acoustic cavitation on antibiotic efficacy in biofilms

  2021cites this paper
• Doxycycline functionalized polymeric nanoparticles inhibit Enterococcus faecalis biofilm formation on dentine.

  2020cites this paper
• Efecto inhibitorio de péptidos de defensa innata derivados de LL-37 en biopelícula de Staphylococcus spp.

  2020cites this paper
• Diffusion of antibiotics through a biofilm in the presence of diffusion and absorption barriers.

  2020cites this paper
• Model of ciprofloxacin subdiffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium

  2020cites this paper
• Modelling experimentally measured of ciprofloxacin antibiotic diffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium

  2020cites this paper
• Microbial Biofilms: Modern Concepts

  2020cites this paper
• Biofilms: Development and molecular interaction of microbiome in the human oral cavity

  2020cites this paper
• Microbial Composition of Oral Biofilms after Visible Light and Water-Filtered Infrared a Radiation (VIS+wIRA) in Combination with Indocyanine Green (ICG) as Photosensitizer

  2020cites this paper
• Scope and limitations on aerosol drug delivery for the treatment of infectious respiratory diseases.

  2020cites this paper
• Capsular contracture around silicone mini-implants following bacterial contamination: An in-vivo comparative experimental study between smooth, textured and polyurethane implants.

  2020cites this paper
• Questions on the role of biofilms for the adaptation of microorganisms to unfavorable environmental factors by the example of P. aeruginosa

  2020cites this paper
• In vitro antimicrobial photodynamic inactivation of multidrug-resistant Acinetobacter baumannii biofilm using Protoporphyrin IX and Methylene blue.

  2020cites this paper
• Phytocompounds vs. Dental Plaque Bacteria: In vitro Effects of Myrtle and Pomegranate Polyphenolic Extracts Against Single-Species and Multispecies Oral Biofilms

  2020cites this paper
• High Potential of Bacterial Adhesion on Block Bone Graft Materials

  2020cites this paper
• The effect of Stenotrophomonas maltophilia on Gram-negative cystic fibrosis pathogens.

  2019cites this paper
• Fabrication of silicon nanopillar arrays by electron beam lithography and reactive ion etching for advanced bacterial adhesion studies

  2019cites this paper
• Inactivation of oral biofilms using visible light and water-filtered infrared A radiation and indocyanine green.

  2019cites this paper
• Разработка фармакопейных стандартов качества на лекарственные препараты - бактериофаги

  2019cites this paper
• Challenges of biofilm control and utilization: lessons from mathematical modelling

  2019cites this paper
• Antimicrobial Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (VIS + wIRA) and Hypericum Perforatum Modifies In Situ Oral Biofilms

  2019cites this paper
• Quantitative and Compositional Study of Monospecies Biofilms of Spoilage Microorganisms in the Meat Industry and Their Interaction in the Development of Multispecies Biofilms

  2019cites this paper
• The emergence of biofilms : Computational and experimental studies

  2019cites this paper
• Simulation-Based Exploration of Quorum Sensing Triggered Resistance of Biofilms to Antibiotics

  2018cites this paper
• A 3D individual‐based model to investigate the spatially heterogeneous response of bacterial biofilms to antimicrobial agents

  2018cites this paper
• How do environment-dependent switching rates between susceptible and persister cells affect the dynamics of biofilms faced with antibiotics?

  2018cites this paper
• Bioactive Coatings and Antibacterial Approaches for Titanium Medical Implants

  2018cites this paper
• Near-Infrared Light-Activated Thermosensitive Liposomes as Efficient Agents for Photothermal and Antibiotic Synergistic Therapy of Bacterial Biofilm.

  2018cites this paper
• The action of chemical and mechanical stresses on single and dual species biofilm removal of drinking water bacteria.

  2018cites this paper
• Antimicrobial photodynamic therapy – what we know and what we don’t

  2018cites this paper
• Title 1 A 3 D individual-based model to investigate the spatially heterogeneous response of bacterial 2 biofilms to antimicrobial agents 3

  2018cites this paper
• THE FORMATION BIOFILMS OF YERSINIA PSEUDOTUBERCULOSIS IN WATER SAMPLES OF THE FAR EASTERN SEAS

  2018cites this paper
• Probiotic Lactobacillus Strains and Their Antimicrobial Peptides to Counteract Biofilm- Associated Infections- A Promising Biological Approach

  2018influential citation
• Modeling of continuous-flow bioreactors with a biofilm with the use of orthogonal collocation on finite elements

  2018cites this paper
• Periprosthetic bacterial biofilm and quorum sensing

  2018cites this paper
• Continuum and discrete approach in modeling biofilm development and structure: a review

  2018cites this paper
• Influence of Nutrient Availability and Quorum Sensing on the Formation of Metabolically Inactive Microcolonies Within Structurally Heterogeneous Bacterial Biofilms: An Individual-Based 3D Cellular Automata Model

  2017cites this paper
• Antimicrobial Coatings and Modifications on Medical Devices

  2017cites this paper
• Cellular Automata As An Effective Tool For Modelling Of Biofilm Morphology

  2017cites this paper
• 7 Biofilms Impact on Drinking Water Quality

  2017cites this paper
• Characterization of Surface Modified Orthopedic Implants for Their Antimicrobial Properties

  2017cites this paper
• Influence of Nutrient Availability and Quorum Sensing on the Formation of Metabolically Inactive Microcolonies Within Structurally Heterogeneous Bacterial Biofilms: An Individual-Based 3D Cellular Automata Model

  2017cites this paper
• Low Frequency Ultrasound in Chronic Rhinosinusitis with Nasal Polyposis and Recovery after Endoscopic Sinus Surgery: A Randomized Controlled Trial

  2017cites this paper
• Penetrating the Bacterial Biofilm

  2017cites this paper
• Characterization of Bacterial Adhesion and Biofilm Formation

  2017cites this paper
• Modeling and Simulation of Bacterial Biofilm Treatment with Applications to Food Science

  2017cites this paper
• Combining antibiotic loaded nanocarriers with golden nanoparticles for light-triggered release and biofilm disruption

  2017cites this paper
• Cheating the Cheaters: Spatial Dynamics in the Evolutionary Stability of Antibiotic Resistance

  2017cites this paper
• Biofilm over teeth and restorations: What do we need to know?

  2017cites this paper
• In vitro microbicidal, anti‐biofilm and cytotoxic effects of different commercial antiseptics

  2017cites this paper
• Modeling Reveals the Role of Aging and Glucose Uptake Impairment in L1A1 Listeria monocytogenes Biofilm Life Cycle

  2017cites this paper
• Chapter 3 – Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment

  2017cites this paper
• Dependence of toxicity of silver nanoparticles on Pseudomonas putida biofilm structure.

  2017cites this paper
• Continuum and discrete approach in modeling biofilm development and structure: a review

  2017cites this paper
• The Peculiar Functions of the Bacterial Extracellular Matrix.

  2017cites this paper
• BIOFILM FORMATION AT THE BACTERIAL VAGINOSIS

  2016cites this paper
• Activités anti-biofilm de Lactobacillus vis-à-vis de Klebsiella Pneumoniae

  2016cites this paper
• Incorporation of Farnesol Significantly Increases the Efficacy of Liposomal Ciprofloxacin against Pseudomonas aeruginosa Biofilms in Vitro.

  2016cites this paper
• Positively charged biopolymeric nanoparticles for the inhibition of Pseudomonas aeruginosa biofilms

  2016cites this paper
• Development of the CDWQ-E2 post-treatment water quality model

  2016cites this paper
• Análisis estructural y presencia de autofluorescencia en biopelículas formadas por micobacterias no pigmentadas de crecimiento rápido

  2016cites this paper
• The Relationship of Bacterial Biofilms and Capsular Contracture in Breast Implants.

  2016cites this paper
• Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections

  2016cites this paper
• Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms

  2016cites this paper
• Anti-biofilm Activity as a Health Issue

  2016cites this paper
• Culturing oil sands microbes as mixed species communities enhances ex situ model naphthenic acid degradation

  2015cites this paper
• Cross-diffusion in Biofilms

  2015influential citation
• Evaluation of antimicrobial strategies against biomaterial-associated infections: impact of the surrounding environmental conditions

  2015cites this paper
• Bioflocks structure from enriched lab-scale stabilization ponds used to remove high chromium concentrations

  2015cites this paper
• Strategien zur Kontrolle von Biofilmen

  2015cites this paper
• Transmission and Scanning Electron Microscopy of Contacts between Bacterial and Yeast Cells in Biofilms on Different Surfaces

  2015cites this paper
• Extracellular DNA as an essential component and therapeutic target of microbial biofilm

  2015cites this paper
• Biofilms of Pathogenic Nontuberculous Mycobacteria Targeted by New Therapeutic Approaches

  2015cites this paper
• (1→3)-α-D-Glucan hydrolases in dental biofilm prevention and control: A review.

  2015cites this paper
• A Mixed-Culture Biofilm Model with Cross-Diffusion

  2015influential citation
• Antimicrobial Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (VIS + wIRA) Alters In Situ Oral Biofilms

  2015cites this paper