Recombinant human collagens : characterization of type II collagen expressed in insect cells and production of types I-III collagen in the yeast Pichia pastoris

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  2000

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  Biology, Medicine, Materials Science, Chemistry

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  Open on Semantic Scholar

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• Heterologous protein expression in the methylotrophic yeast Pichia pastoris.

  2000cited by this paper
• Type XIII Collagen Forms Homotrimers with Three Triple Helical Collagenous Domains and Its Association into Disulfide-bonded Trimers Is Enhanced by Prolyl 4-Hydroxylase*

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• Accumulation of properly folded human type III procollagen molecules in specific intracellular membranous compartments in the yeast Pichia pastoris.

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• Expression of an engineered form of recombinant procollagen in mouse milk

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  1999cited by this paper
• Procollagen folding and assembly: the role of endoplasmic reticulum enzymes and molecular chaperones.

  1999cited by this paper
• High‐yield secretion of recombinant gelatins by Pichia pastoris

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• Sequence dependent conformational variations of collagen triple-helical structure

  1999cited by this paper
• Functional phytohemagglutinin (PHA) and Galanthus nivalis agglutinin (GNA) expressed in Pichia pastoris correct N-terminal processing and secretion of heterologous proteins expressed using the PHA-E signal peptide.

  1999cited by this paper
• Coexpression with collagen markedly increases the half-life of the recombinant human prolyl 4-hydroxylase tetramer in the yeast Pichia pastoris.

  1999cited by this paper
• Molecular Cloning and Expression of Major Structural Protein VP1 of the Human Polyomavirus JC Virus: Formation of Virus-Like Particles Useful for Immunological and Therapeutic Studies

  1999cited by this paper
• The structure in solution of the b domain of protein disulfide isomerase*

  1999cited by this paper
• Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector.

  1999cited by this paper
• Critical relationship between glycosylation of recombinant lutropin receptor ectodomain and its secretion from baculovirus-infected insect cells.

  1999cited by this paper
• Does the Triple Helical Domain of Type I Collagen Encode Molecular Recognition and Fiber Assembly while Telopeptides Serve as Catalytic Domains?

  1999cited by this paper
• Collagen Uses in Dermatology – An Update

  1999cited by this paper
• Alkali-Treated Collagen Retained the Triple Helical Conformation and the Ligand Activity for the Cell Adhesion via α2β1 Integrin

  1999cited by this paper
• Characterization of Recombinant Human Type IX Collagen

  1999cited by this paper
• Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases.

  1998cited by this paper
• A strong nitrogen source-regulated promoter for controlled expression of foreign genes in the yeast Pichia pastoris.

  1998cited by this paper
• Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling.

  1998cited by this paper
• Prolyl 4-hydroxylases and their protein disulfide isomerase subunit.

  1998cited by this paper
• A versatile set of vectors for constitutive and regulated gene expression in Pichia pastoris

  1998cited by this paper
• Inhibition of the Self-assembly of Collagen I into Fibrils with Synthetic Peptides

  1998cited by this paper
• Primary Structure, Tissue Distribution, and Chromosomal Localization of a Novel Isoform of Lysyl Hydroxylase (Lysyl Hydroxylase 3)*

  1998cited by this paper
• Cloning and characterization of a third human lysyl hydroxylase isoform.

  1998cited by this paper
• Introduction to Pichia pastoris.

  1998cited by this paper
• Protein disulfide Isomerase Acts as a Molecular Chaperone during the Assembly of Procollagen*

  1998cited by this paper
• Small vectors for expression based on dominant drug resistance with direct multicopy selection.

  1998cited by this paper
• Heritable collagen disorders: from phenotype to genotype.

  1998cited by this paper
• Stable expression of mammalian beta 1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells.

  1998cited by this paper
• Molecular recognition in procollagen chain assembly.

  1998cited by this paper
• HSP47, a collagen-specific molecular chaperone, delays the secretion of type III procollagen transfected in human embryonic kidney cell line 293: a possible role for HSP47 in collagen modification.

  1998cited by this paper
• The Novel Type II Prolyl 4-Hydroxylase Is the Main Enzyme Form in Chondrocytes and Capillary Endothelial Cells, whereas the Type I Enzyme Predominates in Most Cells*

  1998cited by this paper
• N-glycosylation of a baculovirus-expressed recombinant glycoprotein in three insect cell lines

  1998cited by this paper
• Experimental and Theoretical Analyses of the Domain Architecture of Mammalian Protein Disulphide-Isomerase

  1998cited by this paper
• Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum.

  1998cited by this paper
• Production of Recombinant Hydroxylated Human Type III Collagen Fragment in Saccharomyces cerevisiae

  1998cited by this paper
• The collagen triple-helix structure.

  1997cited by this paper
• Direct binding and activation of receptor tyrosine kinases by collagen.

  1997cited by this paper
• Basement-membrane stromal relationships: interactions between collagen fibrils and the lamina densa.

  1997cited by this paper
• The folding catalyst protein disulfide isomerase is constructed of active and inactive thioredoxin modules.

  1997cited by this paper
• Cloning of the Human Prolyl 4-Hydroxylase α Subunit Isoform α(II) and Characterization of the Type II Enzyme Tetramer

  1997cited by this paper
• Formation of recombinant human procollagen I heterotrimers in a baculovirus expression system.

  1997cited by this paper
• Human recombinant alpha1(V) collagen chain. Homotrimeric assembly and subsequent processing.

  1997cited by this paper
• The discoidin domain receptor tyrosine kinases are activated by collagen.

  1997cited by this paper
• Variations on the Intracellular Transport Theme: Maturing Cisternae and Trafficking Tubules

  1997cited by this paper
• Assembly of human prolyl 4‐hydroxylase and type III collagen in the yeast Pichia pastoris: formation of a stable enzyme tetramer requires coexpression with collagen and assembly of a stable collagen requires coexpression with prolyl 4‐hydroxylase

  1997influential reference
• Both the isomerase and chaperone activities of protein disulfide isomerase are required for the reactivation of reduced and denatured acidic phospholipase A2

  1997cited by this paper
• Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter.

  1997cited by this paper
• Cloning and Characterization of a Novel Human Lysyl Hydroxylase Isoform Highly Expressed in Pancreas and Muscle*

  1997cited by this paper
• Expression of Wild-Type and Modified Proα Chains of Human Type I Procollagen in Insect Cells Leads to the Formation of Stable [α1(I)]2α2(I) Collagen Heterotrimers and [α1(I)]3 Homotrimers but Not [α2(I)]3 Homotrimers*

  1997cited by this paper
• Assembly of the herpes simplex virus capsid: characterization of intermediates observed during cell-free capsid formation.

  1996cited by this paper
• Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen

  1996cited by this paper
• Collagen fibril formation.

  1996cited by this paper
• Site-directed Mutagenesis of Human Lysyl Hydroxylase Expressed in Insect Cells

  1996cited by this paper
• Hsp47: a collagen-specific molecular chaperone.

  1996cited by this paper
• Identifying and characterizing a structural domain of protein disulfide isomerase.

  1996cited by this paper
• Collagen-based biomaterials.

  1996cited by this paper
• Collagen-based devices for soft tissue repair.

  1996cited by this paper
• Type-III procollagen assembly in semi-intact cells: chain association, nucleation and triple-helix folding do not require formation of inter-chain disulphide bonds but triple-helix nucleation does require hydroxylation.

  1996cited by this paper
• Characterization of Human Type III Collagen Expressed in a Baculovirus System

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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Another look at collagen V and XI molecules.

  1995cited by this paper
• Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.

  1995cited by this paper
• Complete structural organization of the human alpha 1 (V) collagen gene (COL5A1): divergence from the conserved organization of other characterized fibrillar collagen genes.

  1995cited by this paper
• Efficient gene transfer into human hepatocytes by baculovirus vectors.

  1995cited by this paper
• Introduction to the molecular biology of baculoviruses.

  1995cited by this paper
• Recent developments of collagen-based materials for medical applications and drug delivery systems.

  1995cited by this paper
• Collagen structure and cartilage matrix integrity.

  1995cited by this paper
• Hydration structure of a collagen peptide.

  1995cited by this paper
• Protein disulfide isomerase mutant lacking its isomerase activity accelerates protein folding in the cell

  1995cited by this paper
• Nuclear magnetic resonance characterization of the N‐terminal thioredoxin‐like domain of protein disulfide isomerase

  1995cited by this paper
• New insights into the function of collagens from genetic analysis.

  1995cited by this paper
• Biosynthesis of recombinant human pro-alpha 1(III) chains in a baculovirus expression system: production of disulphide-bonded and non-disulphide-bonded species containing full-length triple helices.

  1995cited by this paper
• Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide.

  1995cited by this paper
• Structure and expression of the human lysyl hydroxylase gene (PLOD): introns 9 and 16 contain Alu sequences at the sites of recombination in Ehlers-Danlos syndrome type VI patients.

  1994cited by this paper
• Heat-shock proteins as molecular chaperones.

  1994cited by this paper
• Hsp47 and the translation-translocation machinery cooperate in the production of alpha 1(I) chains of type I procollagen.

  1994cited by this paper
• Rapid Selection Using G418 of High Copy Number Transformants of Pichia pastoris for High–level Foreign Gene Expression

  1994cited by this paper
• The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase.

  1994cited by this paper
• Calcium binding properties of rabbit liver protein disulfide isomerase.

  1994cited by this paper
• Mutations in the thioredoxin sites of protein disulfide isomerase reveal functional nonequivalence of the N- and C-terminal domains.

  1994cited by this paper
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  1994cited by this paper
• Delayed triple helix formation of mutant collagen from patients with osteogenesis imperfecta.

  1994cited by this paper
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  1994cited by this paper
• Assembly of Collagen Fibrils de Novo from Soluble Precursors: Polymerization and Copolymerization of Procollagen, pN-Collagen, and Mutated Collagens

  1994cited by this paper
• Type XII and XIV collagens mediate interactions between banded collagen fibers in vitro and may modulate extracellular matrix deformability.

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• Molecular chaperones in protein folding: the art of avoiding sticky situations.

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• The complete DNA sequence of Autographa californica nuclear polyhedrosis virus.

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• Chaperone-like activity of protein disulfide isomerase in the refolding of a protein with no disulfide bonds.

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• Protein disulfide isomerase associates with misfolded human lysozyme in vivo.

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• Synthesis of recombinant human procollagen II in a stably transfected tumour cell line (HT1080).

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• Isolation and characterization of the chains of type V/type XI collagen present in bovine vitreous.

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• The essential function of yeast protein disulfide isomerase does not reside in its isomerase activity.

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