Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Antimicrobial Agents and Chemotherapy

• Publication date

  1997-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1128/AAC.41.5.1115PMID 9145878PMCID PMC163859
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Studies on drug monitoring in thrice and once daily treatment with aminoglycosides

  2005cited by this paper
• Pharmacokinetics of Once-Dally Dosing of Gentamicin in Surgical Intensive Care Unitpatients with Openfractures

  1995cited by this paper
• Aminoglycoside dosing weight correction factors for patients of various body sizes

  1995cited by this paper
• Experience with a once-daily aminoglycoside program administered to 2,184 adult patients

  1995influential reference
• Pharmacokinetics of intravenously administered isepamicin in men

  1995cited by this paper
• Pharmacokinetics of once-daily dosing of gentamicin in surgical intensive care unit patients with open fractures.

  1995cited by this paper
• Monitoring serum concentrations for once-daily netilmicin dosing regimens.

  1994cited by this paper
• KINI: a one compartment intravenous pharmacokinetic analysis program.

  1994cited by this paper
• Pharmacokinetics of once-daily amikacin in elderly patients.

  1993cited by this paper
• Once versus thrice daily gentamicin in patients with serious infections.

  1993cited by this paper
• TopFit: a PC-based pharmacokinetic/pharmacodynamic data analysis program.

  1993cited by this paper
• Practicalities of once-daily aminoglycoside dosing.

  1993cited by this paper
• Pharmacokinetic and toxicological evaluation of a once-daily regimen versus conventional schedules of netilmicin and amikacin.

  1991cited by this paper
• Once-daily aminoglycoside therapy

  1991cited by this paper
• Pharmacokinetic evaluation of single daily dose amikacin.

  1991cited by this paper
• Pharmacokinetic evaluation of single daily dose amikacin.

  1991cited by this paper
• Amikacin once daily: a new dosing regimen based on drug pharmacokinetics.

  1990cited by this paper
• Once‐daily dosing decreases renal accumulation of gentamicin and netilmicin

  1989cited by this paper
• Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration.

  1987cited by this paper
• Pharmacokinetics of gentamicin after i.v. infusion or iv bolus.

  1987cited by this paper
• Good antimicrobial prescribing. Aminoglycosides.

  1982cited by this paper
• Gentamicin pharmacokinetics.

  1978cited by this paper
• Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations

  1978cited by this paper
• Prediction of blood levels after multiple doses from single-dose blood level data: data generated with two-compartment open model analyzed according to the one-compartment open model.

  1969influential reference

• Impact of repeated intranasal gentamicin irrigation on structure and function of the vestibular brainstem

  2025cites this paper
• Role of therapeutic drug monitoring in the treatment of multi-drug resistant tuberculosis

  2024cites this paper
• Population pharmacokinetic/pharmacodynamic evaluations of amikacin dosing in critically ill patients undergoing continuous venovenous hemodiafiltration.

  2023cites this paper
• A Pharmacodynamic Study of Aminoglycosides against Pathogenic E. coli through Monte Carlo Simulation

  2023cites this paper
• A novel strategy for therapeutic drug monitoring: application of biosensors to quantify antimicrobials in biological matrices.

  2023cites this paper
• Use of a common spreadsheet program to demonstrate the ability of Bayesian forecasting to estimate the pharmacokinetic parameters of antibiotics.

  2023cites this paper
• Aminoglycoside Pharmacokinetics in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

  2022influential citation
• MPC-Based Prediction of Anti-Mutant Effectiveness of Antibiotic Combinations: In Vitro Model Study with Daptomycin and Gentamicin against Staphylococcus aureus

  2021cites this paper
• Aminoglycosides in the Intensive Care Unit: What Is New in Population PK Modeling?

  2021cites this paper
• Evaluation of amoxicillin, metronidazole and gentamicin dosage regimens for use in antibiotic prophylaxis in colorectal surgery.

  2021cites this paper
• Therapeutic Drug Monitoring in Tuberculosis

  2021cites this paper
• Guideline-Discordant Preoperative Gentamicin Dosing and the Risk of Gentamicin Associated Nephrotoxicity in Urologic Surgery.

  2021cites this paper
• Hearing Loss: Environmental, Sensorineural, Drug Induced (Cisplatin, Antibiotics)

  2021cites this paper
• Application of Physiologically Based Pharmacokinetic‐Pharmacodynamic Modeling in Preterm Neonates to Guide Gentamicin Dosing Decisions and Predict Antibacterial Effect

  2021cites this paper
• Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus

  2020cites this paper
• Identification of FDA-Approved Drugs with Activity against Stationary Phase Bartonella henselae

  2019cites this paper
• Cells released from S. epidermidis biofilms present increased antibiotic tolerance to multiple antibiotics

  2019cites this paper
• Population Pharmacokinetic Modeling of Gentamicin in Pediatrics

  2019cites this paper
• Reappraisal of Contemporary Pharmacokinetic and Pharmacodynamic Principles for Informing Aminoglycoside Dosing

  2018cites this paper
• Extended Interval Tobramycin Pharmacokinetics in a Pediatric Patient With Primary Ciliary Dyskinesia Presenting With an Acute Respiratory Exacerbation.

  2018cites this paper
• The practice of once-daily aminoglycoside dosing in Canada: A national survey

  2018cites this paper
• Amikacin Dosing for MDR Tuberculosis: A Systematic Review to Establish or Revise the Current Recommended Dose for Tuberculosis Treatment.

  2018cites this paper
• A prospective study evaluating tobramycin pharmacokinetics and optimal once daily dosing in burn patients.

  2017cites this paper
• Evaluation of daptomycin combinations with cephalosporins or gentamicin against Streptococcus mitis group strains in an in vitro model of simulated endocardial vegetations (SEVs)

  2017cites this paper
• Evaluation of Amikacin Pharmacokinetics and Pharmacodynamics for Optimal Initial Dosing Regimen

  2017cites this paper
• Carvacrol is highly disruptive against coagulase-negative staphylococci in in vitro biofilms.

  2017cites this paper
• Quelle est la dose de gentamicine qui permettrait d’obtenir l’objectif de pic de concentration de 30 mg/L défini par les recommandations de l’Agence Nationale de Sécurité du Médicament et des produits de santé ?

  2016cites this paper
• Assessment of the National French recommendations regarding the dosing regimen of 8mg/kg of gentamicin in patients hospitalised in intensive care units.

  2016cites this paper
• Bactericidal activity of penicillin, ceftriaxone, gentamicin and daptomycin alone and in combination against Aerococcus urinae.

  2016cites this paper
• Study of the susceptibility to antibiotics of cells released from Staphylococcus epidermidis biofilms

  2016cites this paper
• Scaling clearance in paediatric pharmacokinetics: All models are wrong, which are useful?

  2016cites this paper
• Population pharmacokinetics of arbekacin in different infectious disease settings and evaluation of dosing regimens.

  2016cites this paper
• Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

  2016cites this paper
• Adequacy of a hospital-wide standard dose of 7mg/kg bodyweight gentamicin sufficient to achieve an adequate prophylactic maximum serum concentration (Cmax) in burn patients undergoing surgical burn wound treatment.

  2016cites this paper
• Single Daily Dose of Aminoglycosides in comparison with Multiple Daily Dose in Iraq

  2016cites this paper
• Étude de la nébulisation de deux antibiotiques en ventilation mécanique

  2016cites this paper
• Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

  2016cites this paper
• First-dose pharmacokinetics of aminoglycosides in critically ill haematological malignancy patients.

  2015cites this paper
• Once-daily aminoglycoside dosing: An update on current literature.

  2015cites this paper
• Inefficacy of vancomycin and teicoplanin in eradicating and killing Staphylococcus epidermidis biofilms in vitro.

  2015cites this paper
• Gentamicin and Renal Function: Lessons From 15 Years' Experience of a Pharmacokinetic Service for Extended Interval Dosing of Gentamicin

  2015cites this paper
• Infectious Diseases Pharmacotherapy for Children With Cystic Fibrosis.

  2015cites this paper
• Pharmacokinetics and Pharmacodynamics of Antibacterial and Antifungal Agents in Adult Patients With Thermal Injury: A Review of Current Literature

  2015cites this paper
• Clinical practice guidelines for therapeutic drug monitoring of arbekacin: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring.

  2014cites this paper
• Therapeutic Drug Monitoring in the Treatment of Tuberculosis: An Update

  2014cites this paper
• Aminoglycoside dosing in patients by kidney function and area under the curve: the Sawchuk-Zaske dosing method revisited in the era of obesity.

  2014cites this paper
• Population Pharmacokinetics of Gentamicin and Dosing Optimization for Infants

  2014cites this paper
• Therapy of intracellular Staphylococcus aureus by tigecyclin

  2013cites this paper
• Practice guidelines for therapeutic drug monitoring of voriconazole: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

  2013cites this paper
• Combination therapy for carbapenem-resistant Gram-negative bacteria

  2013cites this paper
• Combination therapy for carbapenem-resistant

  2013cites this paper
• Clinical efficacy and safety of arbekacin sulfate in patients with MRSA sepsis or pneumonia: a multi-institutional study

  2013cites this paper
• Progress in strategies for dosage regimen individualization.

  2012cites this paper
• Antibiotic Use in Home Health

  2012cites this paper
• Efficacy of Ciprofloxacin-Gentamicin Combination Therapy in Murine Bubonic Plague

  2012cites this paper
• Therapeutic Drug Monitoring in the Treatment of Tuberculosis

  2012cites this paper
• Effects of Obesity and Sex on Antimicrobial Pharmacokinetics and Acute Kidney Injury: Validation of a Preclinical Model

  2012cites this paper
• Population pharmacokinetics of amikacin in a Korean clinical population.

  2011cites this paper
• Optimizing aminoglycoside use.

  2011cites this paper
• Use of antibacterial agents in renal failure.

  2011cites this paper
• Extended-interval aminoglycoside therapy for adult patients with febrile neutropenia: a systematic review.

  2011cites this paper
• Pharmacokinetics of antibiotics in adults with major burns

  2011cites this paper
• Aminoglycoside Pharmacokinetic Parameters in Neurocritical Care Patients Undergoing Induced Hypothermia

  2010cites this paper
• THESE DE L'UNIVERSITE DE LYON Délivrée par L'UNIVERSITE CLAUDE BERNARD LYON 1

  2010cites this paper
• Evaluation of various gentamicin dosage regimens in geriatric patients: a simulation study

  2010cites this paper
• Extended‐Interval Once‐Daily Dosing of Aminoglycosides in Adult and Pediatric Patients with Cystic Fibrosis

  2010cites this paper
• The Safety Profile of Single Daily Dose of Aminoglycosides in Comparison with Multiple Daily Dose

  2009cites this paper
• Modified diet in renal disease method overestimates renal function in selected elderly patients.

  2009cites this paper
• Use of antibacterial agents in renal failure.

  2009cites this paper
• Aminoglycoside Clearance is a Good Estimate of Creatinine Clearance in Intensive Care Unit Patients

  2009cites this paper
• Modélisation pharmacocinétique-pharmacodynamique et techniques de simulation appliquées à l’évaluation de stratégies thérapeutiques en infectiologie

  2009cites this paper
• Population Pharmacokinetics of Amikacin in Indian Pediatric Patients

  2008cites this paper
• Antimicrobial breakpoints for gram-negative aerobic bacteria based on pharmacokinetic-pharmacodynamic models with Monte Carlo simulation.

  2008cites this paper
• Therapeutic drug monitoring of once daily tobramycin in cystic fibrosis--caution with trough concentrations.

  2007cites this paper
• ACTIVITY OF DAPTOMYCIN ALONE AND IN COMBINATION WITH RIFAMPIN AND GENTAMICIN AGAINST STAPHYLOCOCCUS AUREUS BY TIME-KILL METHODOLOGY

  2007cites this paper
• Activity of Daptomycin Alone and in Combination with Rifampin and Gentamicin against Staphylococcus aureus Assessed by Time-Kill Methodology

  2007cites this paper
• Amikacin Dosing and Monitoring in Spinal Cord Injury Patients: Variation in Clinical Practice Between Spinal Injury Units and Differences in Experts' Recommendations

  2006cites this paper
• Chemoprophylactic and bactericidal efficacy of 80 mg gentamicin in a single and once-daily dosing

  2005cites this paper
• Use of antibacterial agents in renal failure.

  2004cites this paper
• Multiple once-daily dose pharmacokinetics and renal safety of gentamicin in dogs.

  2004cites this paper
• Population pharmacokinetics of gentamicin in hospitalized patients receiving once-daily dosing.

  2004cites this paper
• Tobramycin Pharmacokinetics in Children with Febrile Neutropenia Undergoing Stem Cell Transplantation: Once‐Daily versus Thrice‐Daily Administration

  2004cites this paper
• Validation of a Simplified Netilmicin Dosage Regimen in Infants

  2004cites this paper
• Pharmacodynamics and dosing of aminoglycosides.

  2003cites this paper
• Pharmacokinetic Analysis of Once-Daily Gentamicin in Immune-Compromised Adults with Normal Renal Function

  2002cites this paper
• Evaluation of Four Once‐Daily Aminoglycoside Dosing Nomograms

  2002cites this paper
• Distribution and elimination of tobramycin administered in single or multiple daily doses in adult patients with cystic fibrosis.

  2002cites this paper
• Extended-Interval Dosing of Aminoglycoside Antibiotics in Critically Ill Patients

  2002cites this paper
• A Dose‐Ranging Study of Gentamicin Pharmacokinetics: Implications for Extended Interval Aminoglycoside Therapy

  2001cites this paper
• Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations

  2001influential citation
• Evaluation of two in vitro pharmacodynamic simulation models: microfiltration versus centrifugation-filtration.

  2001cites this paper
• Efficacy of once‐daily tobramycin monotherapy for acute pulmonary exacerbations of cystic fibrosis: A preliminary study *

  2001cites this paper
• Pharmacokinetics of Gentamicin C1, C1a, and C2 in Beagles after a Single Intravenous Dose

  2000cites this paper
• DOSE ÚNICA VERSUS DOSE FRACIONADA DIÁRIA DE GENTAMICINA: CONCENTRAÇÃO DE GENTAMICINA NA BILE E SUA RELAÇÃO COM A CONCENTRAÇÃO INIBITÓRIA MÍNIMA DAS BACTÉRIAS RESPONSÁVEIS PELAS INFECÇÕES DAS VIAS BILIARES.

  2000cites this paper
• Bactericidal Activity of Gentamicin againstEnterococcus faecalis In Vitro and In Vivo

  2000cites this paper
• Single daily dosing of aminoglycosides--A community standard?

  2000cites this paper
• Use of antibacterial agents in renal failure.

  2000cites this paper
• Population pharmacokinetics of tobramycin in hospitalized patients receiving once-daily dosing regimen.

  2000cites this paper
• In-vitro activity of combined ampicillin and ciprofloxacin against high-level gentamicin-resistant strains of Enterococcus faecium: influence of the medium on susceptibility test results.

  1998cites this paper
• Pharmacokinetic analysis of amikacin twice and single daily dosage in immunocompromised pediatric patients

  1998cites this paper