Non-Coding RNAs Including miRNAs and lncRNAs in Cardiovascular Biology and Disease

It has been recognized for decades that proteins, which are encoded by our genome and produced via transcription and translation steps, are building blocks that play vital roles in almost all biological processes. Mutations identified in many protein-coding genes are linked to various human diseases. However, this “protein-centered” dogma has been challenged in recent years with the discovery that the majority of our genome is “non-coding” yet transcribed. Non-coding RNA has become the focus of “next generation” biology. Here, we review the emerging field of non-coding RNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), and their role in cardiovascular function and disease.

• Publication year

  2014

• Venue

  Cells

• Publication date

  2014-08-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3390/cells3030883PMID 25153164PMCID 4197640
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inhibition of miR-25 Improves Cardiac Contractility in the Failing Heart

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• CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation

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• Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

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• Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

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• Multifaceted roles of miR-1s in repressing the fetal gene program in the heart

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• Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.

  2014cited by this paper
• The rise of regulatory RNA

  2014cited by this paper
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• Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction

  2014cited by this paper
• Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study.

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• Circulating p53-Responsive MicroRNAs Are Predictive Indicators of Heart Failure After Acute Myocardial Infarction

  2013cited by this paper
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• lincRNAs: genomics, evolution, and mechanisms.

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  2013cited by this paper
• The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

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• microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart

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• Reprogramming of human fibroblasts toward a cardiac fate

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• Braveheart, a long noncoding RNA required for cardiovascular lineage commitment.

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• Targeted Deletion of MicroRNA-22 Promotes Stress-Induced Cardiac Dilation and Contractile Dysfunction

  2012cited by this paper
• MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

  2012influential reference
• microRNAs in cardiovascular development.

  2012cited by this paper
• Functional screening identifies miRNAs inducing cardiac regeneration

  2012cited by this paper
• Heart repair by reprogramming non-myocytes with cardiac transcription factors

  2012cited by this paper
• MicroRNAs in heart development.

  2012cited by this paper
• The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

  2012cited by this paper
• Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

  2012cited by this paper
• Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

  2012cited by this paper
• MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death.

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• The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

  2011cited by this paper
• MicroRNA-24 Regulates Vascularity After Myocardial Infarction

  2011cited by this paper
• Abstract 10466: In Vivo Reprogramming of Murine Cardiac Fibroblasts into Induced Cardiomyocytes

  2011cited by this paper
• miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

  2011cited by this paper
• β-MyHC and cardiac hypertrophy: size does matter.

  2011cited by this paper
• Pervasive roles of microRNAs in cardiovascular biology

  2011cited by this paper
• A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

  2011cited by this paper
• miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes

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• MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease

  2010cited by this paper
• Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.

  2010cited by this paper
• Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice.

  2010cited by this paper
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• Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486

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• Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.

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• miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy

  2009cited by this paper
• MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.

  2009cited by this paper
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• MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

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• miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events.

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• MicroRNA Expression Signature and the Role of MicroRNA-21 in the Early Phase of Acute Myocardial Infarction*

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• miR-1 Overexpression Enhances Ca2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56α and Causing CaMKII-Dependent Hyperphosphorylation of RyR2

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• Long-Term Cardiac-Targeted RNA Interference for the Treatment of Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy

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• MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

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• Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

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• Evidence for Cardiomyocyte Renewal in Humans

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• Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

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• Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis.

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• Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.

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• Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury

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• Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction

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• A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

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• Silencing of microRNAs in vivo with ‘antagomirs’

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  2020cites this paper
• CeRNA regulatory network-based analysis to study the roles of noncoding RNAs in the pathogenesis of intrahepatic cholangiocellular carcinoma

  2020cites this paper
• Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.

  2020cites this paper
• CCL6 aggravates hypoxia-reoxygenation-induced apoptosis in H9c2 cells through enhancing the expression of IGF2-AS.

  2020cites this paper
• Role of Non-Coding Variants in Brugada Syndrome

  2020cites this paper
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  2020cites this paper
• The Functions of LncRNA in the Heart.

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• Silencing of ATP2B1‐AS1 contributes to protection against myocardial infarction in mouse via blocking NFKBIA‐mediated NF‐κB signalling pathway

  2020cites this paper
• Geniposide alleviates hypoxia-induced injury by down-regulation of lncRNA THRIL in rat cardiomyocytes derived H9c2 cells.

  2019cites this paper
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• MicroRNA-24 attenuates vascular remodeling in diabetic rats through PI3K/Akt signaling pathway.

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• TUG1 alleviates hypoxia injury by targeting miR-124 in H9c2 cells.

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• miR-21 Contributes to Human Amniotic Membrane-Derived Mesenchymal Stem Cell Growth and Human Amniotic Membrane-Derived Mesenchymal Stem Cell-Induced Immunoregulation

  2018cites this paper
• Effect of Sodium Thiosulfate Postconditioning on Ischemia-Reperfusion Injury Induced Mitochondrial Dysfunction in Rat Heart

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• Single nucleotide polymorphisms of microRNA in cardiovascular diseases.

  2018cites this paper
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• Interplay between cardiac transcription factors and non-coding RNAs in predisposing to atrial fibrillation

  2018cites this paper
• Non-coding RNAs and exercise: pathophysiological role and clinical application in the cardiovascular system.

  2018cites this paper
• Current status and strategies of long noncoding RNA research for diabetic cardiomyopathy

  2018cites this paper
• miR‐193b availability is antagonized by LncRNA‐SNHG7 for FAIM2‐induced tumour progression in non‐small cell lung cancer

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  2018cites this paper
• Construction of a long non-coding RNA-associated ceRNA network reveals potential prognostic lncRNA biomarkers in hepatocellular carcinoma.

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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
• Genetic and Developmental Basis of Cardiovascular Malformations.

  2016cites this paper
• LncDisease: a sequence based bioinformatics tool for predicting lncRNA-disease associations

  2016cites this paper
• Evaluation of inhibition of miRNA expression induced by anti-miRNA oligonucleotides

  2016cites this paper
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  2016cites this paper
• Long noncoding RNAs in aging and age-related diseases.

  2016cites this paper
• How cardiomyocytes sense pathophysiological stresses for cardiac remodeling

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• Long non-coding RNA ANRIL regulates inflammatory responses as a novel component of NF-κB pathway

  2016cites this paper
• Circulating MicroRNA and Long Noncoding RNA as Biomarkers of Cardiovascular Diseases

  2016cites this paper
• Influence of microRNA-related polymorphisms on clinical outcomes in coronary artery disease.

  2015cites this paper