Peroxisome proliferator-activated receptor γ C161→T polymorphism and coronary artery disease

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Cardiovascular Research

• Publication date

  1999-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0008-6363(99)00256-4
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus.

  1999cited by this paper
• PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

  1998cited by this paper
• The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

  1998cited by this paper
• A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans.

  1998cited by this paper
• Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

  1998cited by this paper
• Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells.

  1998cited by this paper
• The nuclear receptor PPARγ - Bigger than fat

  1998cited by this paper
• A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

  1998cited by this paper
• Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.

  1998cited by this paper
• PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

  1998cited by this paper
• PPARgamma activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes.

  1998cited by this paper
• Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

  1998cited by this paper
• Atherosclerosis is an Inflammatory Disease

  1998cited by this paper
• Obesity associated with a mutation in a genetic regulator of adipocyte differentiation.

  1998cited by this paper
• Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

  1997cited by this paper
• Peroxisome proliferator-activated receptors, orphans with ligands and functions.

  1997cited by this paper
• Chromosomal localization and partial genomic structure of the human peroxisome proliferator activated receptor-gamma (hPPAR gamma) gene.

  1997cited by this paper
• The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene*

  1997cited by this paper
• Differential activation of adipogenesis by multiple PPAR isoforms.

  1996cited by this paper
• Polymorphisms at the 5'-end of the apolipoprotein AI gene and severity of coronary artery disease.

  1996cited by this paper
• The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation.

  1996cited by this paper
• Genes for SMA: multum in parvo.

  1995cited by this paper
• Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms.

  1995cited by this paper
• Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.

  1995cited by this paper
• The adipocyte: storage depot or node on the energy information superhighway?

  1995cited by this paper
• Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor.

  1994cited by this paper
• mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

  1994cited by this paper

• Target gene variations of PPAR isoforms may contribute to MODY heterogeneity: A preliminary comparative study with type 2 diabetes.

  2024cites this paper
• The Influence of FAM13A and PPAR-γ2 Gene Polymorphisms on the Metabolic State of Postmenopausal Women

  2023cites this paper
• G Allele of the rs1801282 Polymorphism in PPARγ Gene Confers an Increased Risk of Obesity and Hypercholesterolemia, While T Allele of the rs3856806 Polymorphism Displays a Protective Role Against Dyslipidemia: A Systematic Review and Meta-Analysis

  2022cites this paper
• PPARγ Gene Polymorphisms, Metabolic Disorders, and Coronary Artery Disease

  2022cites this paper
• The Correlation Between Peroxisome Proliferator-Activated Receptor Alpha and Gamma Polymorphisms and Acute Coronary Syndrome

  2022influential citation
• C1431T Variant of PPARγ Is Associated with Preeclampsia in Pregnant Women

  2021cites this paper
• Associations between peroxisome proliferator-activated receptor γ (PPAR-γ) polymorphisms and serum lipids: two cross-sectional studies of community-dwelling adults.

  2020cites this paper
• The Relationship between IL-1? Gene Polymorphisms and Coronary Artery Disease in Elderly Population

  2019cites this paper
• PON2 and PPARG polymorphisms as biomarkers of risk for coronary heart disease.

  2018cites this paper
• The roles of PPARs in human diseases

  2018cites this paper
• Association of PPAR Alpha Intron 7 G/C, PPAR Gamma 2 Pro12Ala, and C161T Polymorphisms with Serum Fetuin-A Concentrations

  2017cites this paper
• PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part II: PPAR-β/δ and PPAR-γ.

  2017cites this paper
• Association of combined genetic variations in PPARγ, PGC-1α, and LXRα with coronary artery disease and severity in Thai population.

  2016cites this paper
• The C161T Polymorphism in Peroxisome Proliferator-Activated Receptor ɣ2, but Not Pro12Ala, Is Associated with Diabetic Retinopathy in Type 2 Diabetes Mellitus in an Egyptian Population

  2016cites this paper
• Association between peroxisome proliferator-activated receptor-alpha, delta, and gamma polymorphisms and risk of coronary heart disease

  2016cites this paper
• Heterogeneity in Nutritional and Lipid Profiles in Children and Adolescents with Human Immunodeficiency Virus Treated with Highly Active Antiretroviral Therapy

  2015cites this paper
• Impact of the C1431T Polymorphism of the Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ) Gene on Fasted Serum Lipid Levels in Patients with Coronary Artery Disease

  2015cites this paper
• Association between Peroxisome Proliferator-activated Receptor Gamma Gene Polymorphisms and Atherosclerotic Diseases: A Meta-analysis of Case-control Studies.

  2015cites this paper
• Effect of the PPARγ C161T Gene Variant on Serum Lipids in Ischemic Stroke Patients with and Without Type 2 Diabetes Mellitus

  2014cites this paper
• Doenjang, a Korean Fermented Soy Food, Exerts Antiobesity and Antioxidative Activities in Overweight Subjects with the PPAR-γ2 C1431T Polymorphism: 12-Week, Double-Blind Randomized Clinical Trial

  2014cites this paper
• Peroxisome Proliferator-activated Receptor Gamma: Genetic Polymorphisms Are Not Associated With Metabolic Syndrome in Taiwan

  2014cites this paper
• Association of the variants in the PPARG gene and serum lipid levels: a meta-analysis of 74 studies

  2014cites this paper
• Rare Mutations of Peroxisome Proliferator-Activated Receptor Gamma: Frequencies and Relationship with Insulin Resistance and Diabetes Risk in the Mixed Ancestry Population from South Africa

  2014cites this paper
• Associations between C1431T and Pro12Ala variants of PPARγ gene and their haplotypes with susceptibility to metabolic syndrome in an Iranian population

  2014cites this paper
• Association of peroxisome proliferator-activated receptorγ gene Pro12Ala and C161T polymorphisms with cardiovascular risk factors in maintenance hemodialysis patients

  2014cites this paper
• Genetics of antipsychotic-induced weight gain: update and current perspectives.

  2013cites this paper
• Association of peroxisome proliferator-activated receptors/retinoic acid receptors with renal diseases

  2013cites this paper
• The effect of PPARG gene polymorphisms on the risk of coronary heart disease: a meta-analysis

  2013cites this paper
• The C161T polymorphism in the peroxisome proliferator-activated receptor gamma gene (PPARγ) is associated with risk of coronary artery disease: a meta-analysis

  2013cites this paper
• Combined Effects of the C161T and Pro12Ala PPARγ2 Gene Variants with Insulin Resistance on Metabolic Syndrome: A Case–Control Study of a Central Tunisian Population

  2013cites this paper
• Different effects of PPARA, PPARG and ApoE SNPs on serum lipids in patients with coronary heart disease based on the presence of diabetes.

  2013cites this paper
• Koroner kalp hastaliğinda peroksizom proliferatör-aktive reseptör (PPAR) izoformlari

  2013cites this paper
• Peroxisome proliferator-activated receptor (PPAR) isoforms in coronary heart disease

  2013cites this paper
• Role of Peroxisome Proliferator Activated Receptor-gamma and its Ligands in Inflammatory Bowel Disease

  2012cites this paper
• The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course

  2012cites this paper
• Association of PPAR polymorphisms with cytokine levels in allergic rhinitis

  2012cites this paper
• Obesity and eating behaviour in children and adolescents: Contribution of common gene polymorphisms

  2012cites this paper
• The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease

  2012cites this paper
• Association between C1431T polymorphism in peroxisome proliferator-activated receptor-γ gene and coronary artery disease in Chinese Han population

  2012cites this paper
• Peroxisome proliferator-activated receptor gamma in osteoarthritis

  2011cites this paper
• Genetic Polymorphisms in the HTR2C and Peroxisome Proliferator-Activated Receptors Are Not Associated with Metabolic Syndrome in Patients with Schizophrenia Taking Clozapine

  2011cites this paper
• Role of PPARs and their isoforms in metabolic disorders related to insulin resistance and diabetes

  2011cites this paper
• Tagging single nucleotide polymorphisms in the PPAR-γ and RXR-α gene and type 2 diabetes risk: a case-control study of a Chinese Han population

  2011cites this paper
• Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells.

  2011cites this paper
• Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients with and without Type 2 diabetes

  2011cites this paper
• Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes.

  2011cites this paper
• Distribution of peroxisome proliferator–activated receptor–gamma polymorphisms in Chinese and Dutch patients with inflammatory bowel disease

  2010cites this paper
• Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians.

  2010cites this paper
• PPARγ gene C161T substitution alters lipid profile in Chinese patients with coronary artery disease and type 2 diabetes mellitus

  2010cites this paper
• PPAR transcriptional activator complex polymorphisms and the promise of individualized therapy for heart failure

  2010cites this paper
• Retinoid X receptor heterodimer variants and cardiovascular risk factors.

  2009cites this paper
• Molecular genetics of atherosclerosis

  2009cites this paper
• Association between two common polymorphisms of PPARgamma gene and metabolic syndrome families in a Chinese population.

  2009cites this paper
• PPARgamma promoter polymorphisms and acute coronary syndrome.

  2009cites this paper
• Peroxisome Proliferator-Activated Receptor-γ–Mediated Effects in the Vasculature

  2008cites this paper
• PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease

  2008cites this paper
• Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy

  2008cites this paper
• Association of peroxisome proliferator-activated receptorgamma gene Pro12Ala and C161T polymorphisms with metabolic syndrome.

  2008cites this paper
• Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study

  2008cites this paper
• Peroxisome Proliferator-Activated Receptor-Gamma Gene Polymorphism and Risk of Cardiovascular Disease in Patients with Diabetic Nephropathy

  2008cites this paper
• Effect of peroxisome proliferator‐activated receptors‐γ and co‐activator‐1α genetic polymorphisms on plasma adiponectin levels and susceptibility of non‐alcoholic fatty liver disease in Chinese people

  2007cites this paper
• Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome.

  2007cites this paper
• [Peroxisome proliferator-activated receptor gamma (PPARgamma): molecular study in glucose homeostasis, lipid metabolism and therapeutic approach].

  2007cites this paper
• PPAR-γ in the Cardiovascular System

  2007cites this paper
• No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean subjects.

  2007cites this paper
• Peroxisome proliferator‐activated receptors and inflammation: take it to heart

  2007cites this paper
• Variations in the peroxisome proliferator-activated receptor-γ gene and melanoma risk

  2007cites this paper
• Variants of the peroxisome proliferator-activated receptor γ- and β-adrenergic receptor genes are associated with measures of compensatory eating behaviors in young children

  2007cites this paper
• PPARgamma gene C161T substitution is associated with reduced risk of coronary artery disease and decreased proinflammatory cytokine expression.

  2007cites this paper
• Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARγ gene and colorectal cancer risk in Japanese

  2006cites this paper
• Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells.

  2006cites this paper
• Oxidized Lipid-Driven Chemokine Receptor Switch, CCR2 to CX3CR1, Mediates Adhesion of Human Macrophages to Coronary Artery Smooth Muscle Cells Through a Peroxisome Proliferator-Activated Receptor γ–Dependent Pathway

  2006cites this paper
• Effects of two common polymorphisms of peroxisome proliferator-activated receptor-gamma gene on metabolic syndrome.

  2006cites this paper
• Energy balance and food intake: the role of PPARgamma gene polymorphisms.

  2006cites this paper
• Peroxisome Proliferator-Activated Receptors at the Crossroads of Obesity, Diabetes, and Cardiovascular Disease

  2006cites this paper
• The Association of Pro12Ala Polymorphism in PPAR-γ Gene with Coronary Artery Disease in Korean Subjects

  2006cites this paper
• Diabetes per se and metabolic state influence gene expression in tissue‐dependent manner of BB/OK rats

  2005cites this paper
• Peroxisome Proliferator Activated Receptors

  2005cites this paper
• The effects of C161-->T polymorphisms in exon 6 of peroxisome proliferator-activated receptor-gamma gene on bone mineral metabolism and serum osteoprotegerin levels in healthy middle-aged women.

  2005cites this paper
• The Pro12Ala and C–681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren

  2005cites this paper
• Peroxisome proliferator-activated receptor γ polymorphisms affect systemic inflammation and survival in end-stage renal disease patients starting renal replacement therapy

  2005cites this paper
• Effect of the peroxisome proliferator-activated receptor-γ C161T polymorphism on lipid profile in Brazilian patients with Type 2 diabetes mellitus

  2005cites this paper
• Genetic polymorphisms in peroxisome proliferator‐activated receptor γ are associated with Type 2 diabetes mellitus and obesity in the Korean population

  2005cites this paper
• The C161-->T polymorphism in peroxisome proliferator-activated receptor gamma, but not P12A, is associated with insulin resistance in Hispanic and non-Hispanic white women: evidence for another functional variant in peroxisome proliferator-activated receptor gamma.

  2005cites this paper
• Genetics of leptin and obesity: a HuGE review.

  2005cites this paper
• The PPAR genes, cardiovascular disease and the emergence of PPAR pharmacogenetics

  2005cites this paper
• Single nucleotide variants in the β2-adrenergic and β3-adrenergic receptor genes explained 18.3% of adolescent obesity variation

  2005cites this paper
• Peroxisome proliferator-activated receptor β/δ: a new antihypertrophic drug target?

  2005cites this paper
• Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator‐activated receptor‐gamma on colorectal cancer in an Indian population

  2005cites this paper
• Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population.

  2004cites this paper
• Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes

  2004cites this paper
• Impact of genetic variation of PPARγ in humans

  2004cites this paper
• Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology.

  2004cites this paper
• Relation of thrombomodulin gene polymorphisms to acute myocardial infarction in patients

  2004cites this paper
• The 161TT genotype in the exon 6 of the peroxisome-proliferator-activated receptor gamma gene is associated with premature acute myocardial infarction and increased lipid peroxidation in habitual heavy smokers.

  2004cites this paper
• Variations in the genes encoding the peroxisome proliferator-activated receptors α and γ in psoriasis

  2004cites this paper
• Genetic Variation in PPARG Encoding Peroxisome Proliferator-Activated Receptor γ Associated With Carotid Atherosclerosis

  2004cites this paper
• Cardiovascular Risk in Type 2 Diabetes Is Associated With Variation at the PPARG Locus: A Go-DARTS Study

  2004cites this paper
• Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?

  2003cites this paper
• Effect of Trp64Arg mutation of the β3‐adrenergic receptor gene and C161T substitution of the peroxisome proliferator activated receptor γ gene on obesity in Japanese children

  2003cites this paper