Loss of dystrophin and β-sarcoglycan significantly exacerbates the phenotype of laminin α2 chain-deficient animals.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  American Journal of Pathology

• Publication date

  2014-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.ajpath.2013.11.017PMID 24393714
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The congenital muscular dystrophies

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• Epistatic dissection of laminin-receptor interactions in dystrophic zebrafish muscle.

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• Sarcoglycanopathies.

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• Proteasome inhibition improves the muscle of laminin α2 chain-deficient mice.

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• Transgenic expression of Laminin α1 chain does not prevent muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

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• Sparing of extraocular muscle in aging and muscular dystrophies: a myogenic precursor cell hypothesis.

  2011cited by this paper
• Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies

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• Hereditary muscular dystrophies and the heart.

  2010cited by this paper
• Distinct Roles for Laminin Globular Domains in Laminin α1 Chain Mediated Rescue of Murine Laminin α2 Chain Deficiency

  2010cited by this paper
• Dystroglycan versatility in cell adhesion: a tale of multiple motifs

  2010cited by this paper
• Diagnosis and new treatments in muscular dystrophies.

  2009cited by this paper
• Diagnosis and new treatments in muscular dystrophies

  2009cited by this paper
• Inaugural Article: Basal lamina strengthens cell membrane integrity via the laminin G domain-binding motif of -dystroglycan

  2009cited by this paper
• Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice.

  2009cited by this paper
• Biology of the striated muscle dystrophin-glycoprotein complex.

  2008cited by this paper
• Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.

  2006cited by this paper
• Severe muscular dystrophy in mice that lack dystrophin and α7 integrin

  2006cited by this paper
• Laminin α1 chain mediated reduction of laminin α2 chain deficient muscular dystrophy involves integrin α7β1 and dystroglycan

  2006cited by this paper
• Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy.

  2006cited by this paper
• Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.

  2006cited by this paper
• Extraocular muscle is spared upon complete laminin alpha2 chain deficiency: comparative expression of laminin and integrin isoforms.

  2006cited by this paper
• Utrophin upregulation in Duchenne muscular dystrophy.

  2005cited by this paper
• Genetic compensation for sarcoglycan loss by integrin α7β1 in muscle

  2004cited by this paper
• Genetic compensation for sarcoglycan loss by integrin alpha7beta1 in muscle.

  2004cited by this paper
• Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient mice.

  2004cited by this paper
• Laminin α1 chain reduces muscular dystrophy in laminin α2 chain deficient mice

  2004cited by this paper
• Constitutive properties, not molecular adaptations, mediate extraocular muscle sparing in dystrophic mdx mice

  2003cited by this paper
• Disruption of DAG1 in differentiated skeletal muscle reveals a role for dystroglycan in muscle regeneration.

  2002cited by this paper
• Alternative Splice Variants of α7β1Integrin Selectively Recognize Different Laminin Isoforms*

  2002cited by this paper
• Merosin-deficient congenital muscular dystrophy, autosomal recessive (MDC1A, MIM#156225, LAMA2 gene coding for α2 chain of laminin)

  2002cited by this paper
• Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.

  2002cited by this paper
• Enhanced Expression of the α7β1 Integrin Reduces Muscular Dystrophy and Restores Viability in Dystrophic Mice

  2001cited by this paper
• An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy

  2001cited by this paper
• Force and power output of fast and slow skeletal muscles from mdx mice 6‐28 months old

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• Extraocular muscle is spared despite the absence of an intact sarcoglycan complex in gamma- or delta-sarcoglycan-deficient mice.

  2001cited by this paper
• Extraocular muscle is spared despite the absence of an intact sarcoglycan complex in γ- or δ-sarcoglycan-deficient mice

  2001cited by this paper
• Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E.

  2000cited by this paper
• Secondary reduction of alpha7B integrin in laminin alpha2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle.

  1999cited by this paper
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  1999cited by this paper
• Secondary reduction of α7B integrin in laminin α2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle

  1999cited by this paper
• Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α‐dystroglycan and several extracellular matrix proteins

  1999cited by this paper
• Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.

  1999cited by this paper
• Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

  1998cited by this paper
• γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

  1998cited by this paper
• Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice

  1998cited by this paper
• The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.

  1998cited by this paper
• Animal Models for Muscular Dystrophy Show Different Patterns of Sarcolemmal Disruption

  1997cited by this paper
• Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy.

  1997cited by this paper
• Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.

  1997cited by this paper
• Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies.

  1997cited by this paper
• Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.

  1997cited by this paper
• Laminin α2 chain‐null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)‐deficient congenital muscular dystrophy

  1997cited by this paper
• Laminin alpha2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy.

  1997cited by this paper
• Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene.

  1996cited by this paper
• Autosomal recessive limbgirdle muscular dystrophy, LGMD2F, is caused by a mutation in the δ–sarcoglycan gene

  1996cited by this paper
• Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene

  1996cited by this paper
• MyoD is required for myogenic stem cell function in adult skeletal muscle.

  1996cited by this paper
• β–sarcoglycan (A3b) mutations cause autosomal recessive muscular dystrophy with loss of the sarcoglycan complex

  1995cited by this paper
• Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy.

  1995cited by this paper
• Mutations in the laminin α2–chain gene (LAMA2) cause merosin–deficient congenital muscular dystrophy

  1995cited by this paper
• Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy.

  1995cited by this paper
• Absence of extraocular muscle pathology in Duchenne's muscular dystrophy: role for calcium homeostasis in extraocular muscle sparing

  1995cited by this paper
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  1995cited by this paper
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  1992cited by this paper
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• Epidemiology of neuromuscular disorders in the under-20 population in Bologna Province, Italy.

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  1991cited by this paper
• Membrane organization of the dystrophin-glycoprotein complex.

  1991cited by this paper
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  1989cited by this paper
• Dystrophin: the protein product of the Duchenne muscular dystrophy locus.

  1987cited by this paper
• X chromosome-linked muscular dystrophy (mdx) in the mouse.

  1984cited by this paper
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